Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1-207 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 1 | hippie | 37 | 360 | 28 | 28 | 0 |
| ACE2-201 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 68 | 4 | 4 | 0 |
| ACO2-201 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 172 | 16 | 16 | 5 |
| ACOT13-201 | ACOT13 | Q9NPJ3 | Acyl-coenzyme A thioesterase 13 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 23 | 1 | 1 | 0 |
| AGR2-203 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 20 | 1 | 1 | 1 |
| AK5-203 | AK5 | Q9Y6K8 | Adenylate kinase isoenzyme 5 | chr1 | Not Cancer Driver | No | 1 | biogrid | 94 | 161 | 39 | 39 | 0 |
| ATG5-204 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 33 | 25 | 6 | 6 | 1 |
| BACE1-201 | BACE1 | P56817 | Beta-secretase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 34 | 53 | 2 | 2 | 0 |
| BRD4-213 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 143 | 1184 | 132 | 132 | 0 |
| BSG-201 | BSG | P35613 | Basigin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 123 | 16 | 16 | 0 |
| CAPN1-201 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 32 | 0 | 0 | 1 |
| CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 2 | 0 | 0 | 0 |
| CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| CDK15-210 | CDK15 | Q96Q40 | Cyclin-dependent kinase 15 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 36 | 3 | 3 | 0 |
| CFTR-201 | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 216 | 145 | 9 | 9 | 130 |
| CIDEB-203 | CIDEB | Q9UHD4 | Lipid transferase CIDEB | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 23 | 1 | 1 | 0 |
| CIT-201 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 196 | 1020 | 116 | 116 | 3 |
| CLIC1-208 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 27 | 4 | 4 | 0 |
| CLIC4-201 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 49 | 4 | 4 | 0 |
| DDAH1-201 | DDAH1 | O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 45 | 1 | 1 | 0 |
| ECE2-201 | ECE2 | P0DPD6 | Endothelin-converting enzyme 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 150 | 22 | 22 | 0 |
| ECHS1-201 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 7 | 1 | 1 | 14 |
| EIF1B-201 | EIF1B | O60739 | Eukaryotic translation initiation factor 1b | chr3 | Not Cancer Driver | No | 1 | hippie | 10 | 6 | 0 | 0 | 0 |
| EIF6-203 | EIF6 | P56537 | Eukaryotic translation initiation factor 6 | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 17 | 2 | 2 | 0 |
| ELAVL1-201 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 54 | 43 | 5 | 5 | 0 |
| ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 203 | 1792 | 84 | 84 | 1 |
| ETFA-203 | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 34 | 0 | 0 | 3 |
| FAHD2A-201 | FAHD2A | Q96GK7 | Fumarylacetoacetate hydrolase domain-containing protein 2A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 8 | 1 | 1 | 0 |
| FDX1-201 | FDX1 | P10109 | Adrenodoxin, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 61 | 1 | 1 | 0 |
| FEN1-201 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | Census | Yes | 1 | hippie, biogrid | 29 | 111 | 13 | 13 | 0 |
| FH-201 | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 54 | 76 | 4 | 4 | 13 |
| FURIN-201 | FURIN | P09958 | Furin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 283 | 30 | 30 | 0 |
| GCSH-201 | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 26 | 0 | 0 | 0 |
| GLOD4-201 | GLOD4 | Q9HC38 | Glyoxalase domain-containing protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 45 | 2 | 2 | 0 |
| GLRX5-201 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 23 | 0 | 0 | 2 |
| GOT1-201 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 35 | 5 | 5 | 0 |
| GPC1-201 | GPC1 | P35052 | Glypican-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 44 | 168 | 10 | 10 | 0 |
| GPI-201 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 73 | 10 | 10 | 23 |
| GRHPR-201 | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 36 | 3 | 3 | 0 |
| GRPEL1-201 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 88 | 5 | 5 | 0 |
| GSTP1-202 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
| HDHD3-202 | HDHD3 | Q9BSH5 | Haloacid dehalogenase-like hydrolase domain-containing protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 0 | 0 | 0 | 0 |
| HINT2-201 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 29 | 1 | 1 | 0 |
| HSCB-201 | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | hippie | 23 | 25 | 3 | 3 | 0 |
| KSR1-219 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 408 | 46 | 46 | 0 |
| LACTB2-201 | LACTB2 | Q53H82 | Endoribonuclease LACTB2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 21 | 0 | 0 | 0 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 402 | 91 | 13 | 13 | 20 |
| MAP1LC3B-201 | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 4 | 17 | 0 | 0 | 0 |
| MCC-201 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | hippie | 104 | 593 | 69 | 69 | 0 |
| MOK-201 | MOK | Q9UQ07 | MAPK/MAK/MRK overlapping kinase | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 136 | 5 | 5 | 0 |
| MOV10-203 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 90 | 103 | 6 | 6 | 0 |
| MPST-201 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 72 | 9 | 9 | 0 |
| NDUFAB1-201 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| NIT2-201 | NIT2 | Q9NQR4 | Omega-amidase NIT2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| NR2C2-206 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 187 | 13 | 13 | 0 |
| NRP1-206 | NRP1 | O14786 | Neuropilin-1 | chr10 | Compendium | Yes | 1 | hippie, biogrid | 112 | 212 | 25 | 25 | 0 |
| NXF1-201 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 85 | 163 | 28 | 28 | 0 |
| OXCT1-201 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 39 | 3 | 3 | 11 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 30 | 0 | 0 | 6 |
| PDHA1-205 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 43 | 4 | 4 | 19 |
| PDP1-201 | PDP1 | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 96 | 7 | 7 | 0 |
| PGM1-202 | PGM1 | P36871 | Phosphoglucomutase-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 31 | 2 | 2 | 12 |
| PLEKHA4-201 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 115 | 690 | 110 | 110 | 0 |
| POLDIP2-201 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 95 | 8 | 8 | 0 |
| PRKAB1-201 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 21 | 125 | 11 | 11 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | Census | Yes | 1 | hippie | 164 | 190 | 31 | 31 | 2 |
| RAC1-201 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 61 | 2 | 0 | 0 | 6 |
| RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 92 | 46 | 12 | 12 | 2 |
| RHOB-201 | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie | 50 | 20 | 1 | 1 | 0 |
| RHOD-201 | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 10 | 0 | 0 | 0 |
| RHOF-201 | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 15 | 11 | 0 | 0 | 0 |
| RHOH-201 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 32 | 12 | 3 | 3 | 0 |
| RHOJ-201 | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 0 |
| RHOU-201 | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 63 | 6 | 6 | 0 |
| RND2-202 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 17 | 54 | 4 | 4 | 0 |
| RWDD2B-207 | RWDD2B | P57060 | RWD domain-containing protein 2B | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 41 | 0 | 0 | 0 |
| SGTB-201 | SGTB | Q96EQ0 | Small glutamine-rich tetratricopeptide repeat-containing protein beta | chr5 | Not Cancer Driver | No | 1 | hippie | 19 | 114 | 8 | 8 | 0 |
| SH3GL3-202 | SH3GL3 | Q99963 | Endophilin-A3 | chr15 | Not Cancer Driver | No | 1 | hippie | 66 | 84 | 19 | 19 | 0 |
| SPR-201 | SPR | P35270 | Sepiapterin reductase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 19 | 4 | 4 | 2 |
| STX17-201 | STX17 | P56962 | Syntaxin-17 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 81 | 6 | 6 | 0 |
| STXBP1-201 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 112 | 13 | 13 | 19 |
| SUCLG1-201 | SUCLG1 | P53597 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 57 | 9 | 9 | 3 |
| SUCLG2-201 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 12 | 2 | 2 | 0 |
| TATDN1-201 | TATDN1 | Q6P1N9 | Deoxyribonuclease TATDN1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| THEM4-201 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 14 | 0 | 0 | 0 |
| TNIK-204 | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | Not Cancer Driver | No | 1 | hippie | 126 | 782 | 86 | 86 | 0 |
| TRIM25-201 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 226 | 11 | 11 | 0 |
| TTC19-201 | TTC19 | Q6DKK2 | Tetratricopeptide repeat protein 19, mitochondrial | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 20 | 76 | 1 | 1 | 0 |
| YWHAZ-207 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 19 | 81 | 7 | 7 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|