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COPA-201 ,COPA ,P53621
  • Number of Interaction partner in intact: 65
  • Number of Interaction partner in biogrid: 76
  • Number of Interaction partner in hippie: 250
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ABCC6-201 ABCC6 O95255 ATP-binding cassette sub-family C member 6 chr16 Not Cancer Driver No 1 hippie 149 133 17 17 78
ACBD5-201 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 49 335 34 34 0
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 intact, hippie 94 87 10 10 1
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact, hippie 91 142 12 12 10
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
AIM2-202 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 54 79 17 17 0
AKT3-217 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 intact, hippie 71 131 19 19 3
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact, biogrid 233 577 79 79 12
ANAPC2-201 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 94 419 52 52 12
ARAF-202 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 61 181 26 26 0
ARCN1-201 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 3 hippie, biogrid 39 194 22 22 0
ARFGAP1-203 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 Not Cancer Driver No 1 hippie 46 265 31 31 0
ATG101-201 ATG101 Q9BSB4 Autophagy-related protein 101 chr12 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 25 183 12 12 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 biogrid 25 180 17 17 0
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 27 63 5 5 0
BAP1-202 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 Census, Compendium Yes 1 hippie 116 419 42 42 4
BET1L-203 BET1L Q9NYM9 BET1-like protein chr11 Not Cancer Driver No 1 hippie 7 8 0 0 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BRAF-220 BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 hippie 755 311 30 30 35
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 31 213 13 13 0
CCDC107-206 CCDC107 Q8WV48 Coiled-coil domain-containing protein 107 chr9 Not Cancer Driver No 1 hippie, biogrid 9 218 9 9 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CCDC97-201 CCDC97 Q96F63 Coiled-coil domain-containing protein 97 chr19 Not Cancer Driver No 1 hippie, biogrid 42 251 26 26 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CCT3-201 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie 53 95 11 11 0
CD74-201 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 Census Yes 1 hippie 24 186 15 15 0
CD8A-201 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 Not Cancer Driver No 1 hippie 27 28 2 2 1
CDC34-201 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 19 96 7 7 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CEP128-209 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 139 902 117 117 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 216 145 9 9 130
CHMP4B-201 CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 21 201 20 20 2
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
COPA-201 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 hippie 119 158 15 15 4
COPB1-202 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 3 hippie, biogrid 74 95 6 6 1
COPB2-201 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 3 hippie, biogrid 70 114 18 18 0
COPE-201 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 5 intact, hippie, biogrid 20 45 2 2 0
COPG1-201 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 Not Cancer Driver No 5 intact, hippie, biogrid 84 107 11 11 0
COPG2-202 COPG2 Q9UBF2 Coatomer subunit gamma-2 chr7 Not Cancer Driver No 2 hippie, biogrid 21 59 1 1 0
COPZ1-201 COPZ1 P61923 Coatomer subunit zeta-1 chr12 Not Cancer Driver No 4 hippie, biogrid 14 0 0 0 0
COPZ2-210 COPZ2 Q9P299 Coatomer subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 14 39 0 0 0
CRY2-211 CRY2 Q49AN0 Cryptochrome-2 chr11 Not Cancer Driver No 1 hippie 54 100 8 8 0
CTBP2-205 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 36 94 4 4 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 54 102 2 2 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
CUL9-201 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie 239 633 59 59 0
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
DCPS-201 DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 32 55 5 5 1
DDA1-201 DDA1 Q9BW61 DET1- and DDB1-associated protein 1 chr19 Not Cancer Driver No 1 intact, hippie 6 70 6 6 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX20-201 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 Not Cancer Driver No 1 hippie 59 301 20 20 0
DEPDC1B-201 DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 1 hippie, biogrid 54 52 3 3 0
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 17 12 0 0 0
DHX38-201 DHX38 Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 chr16 Not Cancer Driver No 1 hippie 104 625 58 58 1
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 55 17 0 0 10
DSN1-203 DSN1 Q9H410 Kinetochore-associated protein DSN1 homolog chr20 Not Cancer Driver No 1 intact, hippie 40 191 24 24 0
DUT-201 DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 Not Cancer Driver No 1 biogrid 12 128 6 6 1
DUX4-203 DUX4 Q9UBX2 Double homeobox protein 4 chr4 Not Cancer Driver No 1 hippie 0 407 0 0 0
EBAG9-201 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 27 175 25 25 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EDEM3-201 EDEM3 Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 chr1 Not Cancer Driver No 1 hippie 76 304 29 29 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EIF3C-201 EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 biogrid 3 392 1 1 0
ELOVL5-201 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 33 25 2 2 2
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 29 160 18 18 3
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPHA8-201 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 intact, biogrid 156 122 16 16 0
ERGIC2-201 ERGIC2 Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 3 3 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FAM20C-201 FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 21 188 1 1 8
FAM210A-208 FAM210A Q96ND0 Protein FAM210A chr18 Not Cancer Driver No 1 hippie 21 99 10 10 0
FBP1-201 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 24 19 0 0 4
FBXO25-204 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 23 21 0 0 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 289 232 15 15 17
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 2 intact, hippie, biogrid 92 231 26 26 69
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 67 52 6 6 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 50 161 19 19 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 biogrid 203 259 33 33 14
FOXB1-201 FOXB1 Q99853 Forkhead box protein B1 chr15 Not Cancer Driver No 1 intact, hippie 25 114 4 4 0
FOXL1-201 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 intact, hippie 41 213 18 18 0
FOXQ1-201 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 Not Cancer Driver No 1 intact, hippie 22 248 5 5 0
FOXR1-201 FOXR1 Q6PIV2 Forkhead box protein R1 chr11 Census Yes 1 intact, hippie 32 153 20 20 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact 55 352 38 38 0
GCN1-201 GCN1 Q92616 Stalled ribosome sensor GCN1 chr12 Not Cancer Driver No 1 hippie 255 117 13 13 0
GEMIN2-202 GEMIN2 O14893 Gem-associated protein 2 chr14 Not Cancer Driver No 1 hippie 17 97 4 4 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GRWD1-201 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 32 188 9 9 0
HDAC2-205 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 34 145 11 11 0
HECTD1-201 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie 210 992 85 85 0
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 2 intact, hippie 517 971 113 113 1
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 82 252 28 28 0
HUNK-201 HUNK P57058 Hormonally up-regulated neu tumor-associated kinase chr21 Not Cancer Driver No 1 intact 93 327 46 46 0
IFI16-201 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 102 422 61 61 0
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 5 301 4 4 21
INSIG1-201 INSIG1 O15503 Insulin-induced gene 1 protein chr7 Not Cancer Driver No 1 hippie 25 43 1 1 0
INSIG2-201 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 Not Cancer Driver No 1 hippie 27 11 3 3 0
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
ITM2B-204 ITM2B Q9Y287 Integral membrane protein 2B chr13 Not Cancer Driver No 1 intact 15 12 0 0 1
ITSN1-206 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie, biogrid 109 798 50 50 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KCNJ10-210 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 Not Cancer Driver No 1 hippie, biogrid 59 28 6 6 8
KDF1-201 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 43 279 35 35 0
KHDRBS1-202 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 42 362 37 37 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 46 65 13 13 0
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 2 hippie, biogrid 50 223 18 18 1
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LNPK-201 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 48 256 34 34 0
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 90 261 33 33 0
LRRC31-202 LRRC31 Q6UY01 Leucine-rich repeat-containing protein 31 chr3 Not Cancer Driver No 1 hippie 78 81 8 8 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MATR3-201 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 81 613 61 61 3
MECOM-217 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 225 751 120 120 3
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 1 intact, hippie 59 153 18 18 2
MLH1-201 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 Census Yes 1 hippie 65 208 13 13 77
MNDA-201 MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 Not Cancer Driver No 1 intact, hippie, biogrid 142 173 63 63 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MTF1-201 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 Not Cancer Driver No 1 hippie 80 554 56 56 0
MTNR1B-201 MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 2 intact, hippie 80 8 1 1 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NCF1-201 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 intact, hippie 31 181 11 11 1
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NGEF-201 NGEF Q8N5V2 Ephexin-1 chr2 Not Cancer Driver No 1 hippie, biogrid 92 298 24 24 0
NPHP1-203 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 83 260 24 24 1
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 2 intact, hippie, biogrid 133 57 8 8 23
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact, biogrid 214 56 15 15 3
NUBP1-201 NUBP1 P53384 Cytosolic Fe-S cluster assembly factor NUBP1 chr16 Not Cancer Driver No 1 biogrid 25 63 5 5 0
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 2 intact, hippie 49 38 2 2 0
NUP155-201 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 128 221 17 17 1
NUP50-201 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 hippie, biogrid 43 335 30 30 0
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OFD1-201 OFD1 O75665 Centriole and centriolar satellite protein OFD1 chrX Not Cancer Driver No 1 hippie 77 476 25 25 5
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
PANX1-201 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 45 5 5 2
PDGFRB-201 PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 134 233 40 40 7
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PIK3R1-211 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 122 271 50 50 2
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
POLR2C-201 POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 26 108 9 9 0
POMK-201 POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 40 30 7 7 3
POU5F1-201 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 27 186 8 8 0
PPM1G-201 PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie 35 359 28 28 0
PPP2R2A-202 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 biogrid 36 68 6 6 0
PPP6C-201 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 hippie 51 0 0 0 0
PRDM16-201 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 196 834 117 117 1
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PSKH2-201 PSKH2 Q96QS6 Serine/threonine-protein kinase H2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 77 88 17 17 0
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 425 76 5 5 37
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 36 141 17 17 0
PYHIN1-203 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 139 293 81 81 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 64 420 31 31 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 99 232 31 31 3
RNF126-201 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 Not Cancer Driver No 1 hippie 28 184 19 19 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
ROS1-202 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 intact, biogrid 356 197 45 45 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 45 98 7 7 1
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 20 117 12 12 0
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
RPL10-202 RPL10 P27635 Large ribosomal subunit protein uL16 chrX Census, Compendium Yes 1 biogrid 41 9 2 2 4
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RRP1B-201 RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 61 517 40 40 0
RUNX1-202 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 intact 62 361 46 46 2
SACM1L-201 SACM1L Q9NTJ5 Phosphatidylinositol-3-phosphatase SAC1 chr3 Not Cancer Driver No 1 intact, hippie 33 0 0 0 0
SCYL1-201 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 hippie 58 312 23 23 0
SCYL3-203 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 56 250 18 18 0
SDHA-201 SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact, hippie, biogrid 87 72 9 9 7
SEC23A-201 SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 hippie, biogrid 66 73 5 5 1
SEC24C-202 SEC24C P53992 Protein transport protein Sec24C chr10 Not Cancer Driver No 1 hippie, biogrid 100 403 31 31 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 6 60 5 5 0
SF3B1-201 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie, biogrid 205 479 54 54 0
SF3B3-201 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 hippie, biogrid 103 146 16 16 0
SHMT2-201 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 45 58 4 4 1
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SLC15A3-201 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 47 44 1 1 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC25A11-201 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 intact, hippie, biogrid 31 16 1 1 3
SMARCAL1-201 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 98 340 37 37 10
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 41 98 8 8 0
SNRNP70-206 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 28 417 27 27 0
SNW1-201 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 59 487 53 53 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 14 94 9 9 57
SORT1-201 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 intact, hippie 54 110 0 0 0
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 32 312 32 32 0
SPART-202 SPART Q8N0X7 Spartin chr13 Not Cancer Driver No 1 intact, hippie 77 397 49 49 1
SPDL1-201 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie 59 343 34 34 0
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
SRSF3-202 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie, biogrid 8 125 4 4 0
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 93 152 16 16 15
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
STIM1-201 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 55 386 35 35 12
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 49 233 20 20 0
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
STX8-201 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 1 hippie 16 99 5 5 0
STYK1-201 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact, biogrid 67 35 7 7 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUZ12-201 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 55 483 32 32 3
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TCP1-201 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie 34 55 7 7 0
TES-201 TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 28 100 6 6 0
TEX101-201 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 39 2 0 0 0
TGOLN2-201 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 39 401 33 33 0
TMED10-201 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie 19 15 2 2 0
TMED2-201 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 16 25 2 2 0
TMED9-201 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 intact, hippie 12 22 2 2 0
TMEM17-201 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 15 14 1 1 0
TMEM237-203 TMEM237 Q96Q45 Transmembrane protein 237 chr2 Not Cancer Driver No 1 intact, hippie 28 178 14 14 0
TMEM41B-204 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 16 48 2 2 0
TMPO-202 TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 50 414 32 32 0
TNF-208 TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 22 45 2 2 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
TRIP10-201 TRIP10 Q15642 Cdc42-interacting protein 4 chr19 Not Cancer Driver No 1 hippie, biogrid 52 462 45 45 0
TXNIP-204 TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 46 77 10 10 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 25 32 4 4 0
UBXN6-201 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie 50 135 21 21 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UNC93B1-201 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 42 127 3 3 0
UNK-205 UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 60 513 33 33 0
USP11-201 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 104 211 21 21 0
USP14-201 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 38 86 4 4 0
USP49-206 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 56 190 15 15 0
VAMP5-201 VAMP5 O95183 Vesicle-associated membrane protein 5 chr2 Not Cancer Driver No 1 intact, hippie 13 19 1 1 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WBP1-201 WBP1 Q96G27 WW domain-binding protein 1 chr2 Not Cancer Driver No 1 hippie 17 122 9 9 0
WBP2-201 WBP2 Q969T9 WW domain-binding protein 2 chr17 Not Cancer Driver No 1 hippie 23 104 5 5 1
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
XRCC3-211 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 1 intact, hippie 21 35 2 2 1
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 24 41 1 1 0
ZBTB2-201 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 64 216 29 29 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0
ZNF2-203 ZNF2 Q9BSG1 Zinc finger protein 2 chr2 Not Cancer Driver No 1 intact 44 162 12 12 0
ZNF598-202 ZNF598 Q86UK7 E3 ubiquitin-protein ligase ZNF598 chr16 Not Cancer Driver No 1 hippie 68 567 47 47 0
ZNF746-201 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 68 437 43 43 0