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CTSS-201 ,CTSS ,P25774
  • Number of Interaction partner in intact: 3
  • Number of Interaction partner in biogrid: 115
  • Number of Interaction partner in hippie: 136
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTN1-201 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 hippie, biogrid 84 195 25 25 6
ACTN4-201 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie, biogrid 110 244 36 36 7
AIF1L-201 AIF1L Q9BQI0 Allograft inflammatory factor 1-like chr9 Not Cancer Driver No 1 hippie, biogrid 6 44 1 1 0
ANXA2-204 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 38 21 2 2 0
ARL1-201 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 10 4 0 0 0
ARPC3-201 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie, biogrid 10 26 5 5 0
B4GAT1-201 B4GAT1 O43505 Beta-1,4-glucuronyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 38 4 0 0 2
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 13 112 7 7 0
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie, biogrid 27 63 5 5 0
BGLAP-201 BGLAP P02818 Osteocalcin chr1 Not Cancer Driver No 1 hippie 6 21 0 0 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 28 245 16 16 0
CALU-201 CALU O43852 Calumenin chr7 Not Cancer Driver No 1 hippie, biogrid 15 130 9 9 0
CHID1-201 CHID1 Q9BWS9 Chitinase domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 35 4 0 0 0
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 44 412 36 36 0
CLDN3-201 CLDN3 O15551 Claudin-3 chr7 Not Cancer Driver No 1 intact, hippie 12 0 0 0 0
CLGN-201 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 56 257 24 24 0
CNPY2-201 CNPY2 Q9Y2B0 Protein canopy homolog 2 chr12 Not Cancer Driver No 1 hippie, biogrid 22 24 5 5 0
CNPY3-201 CNPY3 Q9BT09 Protein canopy homolog 3 chr6 Not Cancer Driver No 1 hippie, biogrid 18 87 9 9 0
COL14A1-201 COL14A1 Q05707 Collagen alpha-1(XIV) chain chr8 Not Cancer Driver No 1 hippie, biogrid 317 713 148 148 0
COLGALT1-201 COLGALT1 Q8NBJ5 Procollagen galactosyltransferase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 74 116 8 8 3
COQ8A-201 COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 hippie 69 169 21 21 10
CPD-201 CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie, biogrid 90 476 33 33 0
CRELD2-201 CRELD2 Q6UXH1 Protein disulfide isomerase CRELD2 chr22 Not Cancer Driver No 1 hippie, biogrid 33 34 5 5 0
CST3-201 CST3 P01034 Cystatin-C chr20 Not Cancer Driver No 1 hippie 7 31 1 1 2
CST5-201 CST5 P28325 Cystatin-D chr20 Not Cancer Driver No 1 hippie 30 6 2 2 0
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie, biogrid 36 7 2 2 0
CTSS-201 CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CTSZ-201 CTSZ Q9UBR2 Cathepsin Z chr20 Not Cancer Driver No 1 hippie, biogrid 21 10 0 0 0
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 20 13 3 3 1
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 41 141 19 19 2
DNAJB12-203 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 28 227 11 11 0
DNAJC10-201 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie, biogrid 77 37 3 3 0
DNAJC3-202 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 40 131 13 13 0
DPM1-203 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 Not Cancer Driver No 1 hippie, biogrid 24 29 1 1 3
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie, biogrid 77 61 4 4 2
ERLIN2-204 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie, biogrid 29 22 2 2 0
ERO1A-201 ERO1A Q96HE7 ERO1-like protein alpha chr14 Not Cancer Driver No 1 hippie 34 33 4 4 0
ERP29-201 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 hippie, biogrid 24 34 4 4 0
ERP44-201 ERP44 Q9BS26 Endoplasmic reticulum resident protein 44 chr9 Not Cancer Driver No 1 hippie, biogrid 33 43 3 3 0
FKBP10-201 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie, biogrid 48 134 6 6 3
GANAB-202 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie, biogrid 91 133 17 17 3
GXYLT1-202 GXYLT1 Q4G148 Glucoside xylosyltransferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 37 7 0 0 0
HAGH-202 HAGH Q16775 Hydroxyacylglutathione hydrolase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 23 42 0 0 0
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie, biogrid 38 125 16 16 0
HSD17B12-201 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 Not Cancer Driver No 1 hippie, biogrid 25 10 0 0 0
HSP90B1-201 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 56 269 17 17 0
HYOU1-218 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 98 373 36 36 0
IKBIP-202 IKBIP Q70UQ0 Inhibitor of nuclear factor kappa-B kinase-interacting protein chr12 Not Cancer Driver No 1 hippie, biogrid 31 70 7 7 0
IPO4-201 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie, biogrid 78 87 3 3 0
IRF2-201 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 60 290 52 52 0
KNG1-203 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 1 hippie 100 297 55 55 1
KRI1-201 KRI1 Q8N9T8 Protein KRI1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 69 615 62 62 0
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LRPAP1-205 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 Not Cancer Driver No 1 hippie, biogrid 29 189 16 16 0
MANF-204 MANF P55145 Mesencephalic astrocyte-derived neurotrophic factor chr3 Not Cancer Driver No 1 hippie, biogrid 11 1 0 0 0
MESD-201 MESD Q14696 LRP chaperone MESD chr15 Not Cancer Driver No 1 hippie 22 150 12 12 0
MIA3-202 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 148 1495 126 126 0
MICOS13-201 MICOS13 Q5XKP0 MICOS complex subunit MIC13 chr19 Not Cancer Driver No 1 hippie 9 3 0 0 0
MINPP1-202 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 34 46 1 1 3
MLF2-201 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 32 189 27 27 0
MMS19-209 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie, biogrid 54 11 0 0 0
MOGS-203 MOGS Q13724 Mannosyl-oligosaccharide glucosidase chr2 Not Cancer Driver No 1 hippie, biogrid 80 201 21 21 2
MRTO4-201 MRTO4 Q9UKD2 mRNA turnover protein 4 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 15 73 2 2 0
MYDGF-201 MYDGF Q969H8 Myeloid-derived growth factor chr19 Not Cancer Driver No 1 hippie 16 26 4 4 0
MYO18A-203 MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie, biogrid 181 1246 112 112 0
MYO1B-204 MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie, biogrid 103 35 3 3 0
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 hippie, biogrid 86 66 9 9 0
MYO1D-201 MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 93 61 5 5 0
MYO6-202 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie, biogrid 92 335 9 9 3
NAMPT-201 NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 Not Cancer Driver No 1 hippie, biogrid 39 27 5 5 0
NOC2L-201 NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 54 281 22 22 0
NOMO3-202 NOMO3 P69849 BOS complex subunit NOMO3 chr16 Not Cancer Driver No 1 hippie, biogrid 27 129 1 1 0
NUCB2-207 NUCB2 P80303 Nucleobindin-2 chr11 Not Cancer Driver No 1 hippie, biogrid 35 266 31 31 0
NUP188-201 NUP188 Q5SRE5 Nucleoporin NUP188 chr9 Not Cancer Driver No 1 hippie, biogrid 134 152 18 18 0
NUP210-201 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 213 157 14 14 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 intact, hippie 44 244 18 18 1
OS9-202 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 1 hippie, biogrid 62 451 43 43 0
P4HA1-204 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 47 54 3 3 0
PDIA3-201 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie, biogrid 34 98 6 6 0
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PFKL-201 PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 hippie, biogrid 68 29 2 2 0
PFKP-203 PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 Not Cancer Driver No 1 hippie, biogrid 84 43 4 4 0
PIGS-202 PIGS Q96S52 GPI transamidase component PIG-S chr17 Not Cancer Driver No 1 hippie, biogrid 45 32 3 3 2
PLCG1-202 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 129 187 15 15 0
PLD3-207 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 hippie, biogrid 51 62 6 6 0
PLOD1-201 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 12 0 0 5
PLOD3-201 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 Not Cancer Driver No 1 hippie, biogrid 80 65 6 6 1
POFUT1-202 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 Not Cancer Driver No 1 hippie, biogrid 37 17 0 0 0
PON2-201 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 25 13 0 0 0
PRDX4-202 PRDX4 Q13162 Peroxiredoxin-4 chrX Not Cancer Driver No 1 hippie, biogrid 31 29 2 2 0
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie, biogrid 385 421 43 43 2
RALY-201 RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie, biogrid 46 187 22 22 0
RBM11-201 RBM11 P57052 Splicing regulator RBM11 chr21 Not Cancer Driver No 1 hippie, biogrid 47 125 23 23 0
RCN1-201 RCN1 Q15293 Reticulocalbin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 22 158 13 13 0
RNF5-203 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 Not Cancer Driver No 1 hippie, biogrid 12 69 1 1 0
RPF2-203 RPF2 Q9H7B2 Ribosome production factor 2 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 23 94 7 7 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
SDF2-201 SDF2 Q99470 Stromal cell-derived factor 2 chr17 Not Cancer Driver No 1 hippie, biogrid 19 93 12 12 0
SDF2L1-201 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 12 130 7 7 0
SEC16A-210 SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie, biogrid 196 1931 161 161 0
SEC61A1-201 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 0 0 0 3
SEL1L-201 SEL1L Q9UBV2 Protein sel-1 homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 64 188 10 10 0
SELENOF-201 SELENOF O60613 Selenoprotein F chr1 Not Cancer Driver No 1 hippie 5 0 0 0 0
SERPINB3-201 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie 116 47 23 23 0
SERPINB4-201 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 1 hippie 101 48 16 16 0
SERPINH1-201 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie, biogrid 45 53 5 5 1
SLC25A11-201 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 hippie, biogrid 31 16 1 1 3
SLC25A13-201 SLC25A13 Q9UJS0 Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 73 23 2 2 1
SLPI-201 SLPI P03973 Antileukoproteinase chr20 Not Cancer Driver No 1 hippie 12 0 0 0 0
SPTAN1-202 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 236 983 84 84 0
SRPRB-206 SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 hippie, biogrid 22 23 3 3 0
STT3A-201 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie, biogrid 60 27 1 1 4
STT3B-201 STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 hippie, biogrid 48 136 8 8 0
SUN1-203 SUN1 O94901 SUN domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 81 247 26 26 0
TMED10-201 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 19 15 2 2 0
TMTC3-201 TMTC3 Q6ZXV5 Protein O-mannosyl-transferase TMTC3 chr12 Not Cancer Driver No 1 hippie, biogrid 90 82 4 4 2
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 11 83 5 5 0
TOR1AIP1-212 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 53 400 33 33 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie, biogrid 2742 282 1364 1364 60
TPM4-218 TPM4 P67936 Tropomyosin alpha-4 chain chr19 Census Yes 1 hippie, biogrid 21 216 21 21 0
TTC17-201 TTC17 Q96AE7 Tetratricopeptide repeat protein 17 chr11 Not Cancer Driver No 1 hippie, biogrid 121 277 37 37 0
TUBG1-201 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie, biogrid 42 44 9 9 3
TWF1-201 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 25 52 1 1 0
TXNDC12-201 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 Not Cancer Driver No 1 hippie, biogrid 13 44 3 3 0
UBR4-204 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 Not Cancer Driver No 1 hippie, biogrid 433 1069 97 97 0
UGGT1-201 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 113 162 14 14 0
UGGT2-203 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 Not Cancer Driver No 1 hippie, biogrid 136 65 5 5 0
WDR1-202 WDR1 O75083 WD repeat-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 52 30 4 4 2
XPO5-201 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie, biogrid 85 64 6 6 0
XPOT-201 XPOT O43592 Exportin-T chr12 Not Cancer Driver No 1 hippie, biogrid 83 0 0 0 0
YTHDF3-205 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 57 409 39 39 0