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DARS2-212 ,DARS2 ,Q6PI48
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 113
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2-201 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 91 203 23 23 5
ABHD10-201 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 29 7 2 2 0
ACAA2-201 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 32 52 1 1 0
ACBD3-201 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 1 hippie 21 350 12 12 0
ACSM5-201 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 133 87 24 24 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 3 hippie, biogrid 61 166 20 20 10
AIMP2-201 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 30 61 5 5 0
AK4-201 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 24 2 2 0
ALDH18A1-202 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 Not Cancer Driver No 1 hippie 68 86 8 8 13
AMACR-201 AMACR Q9UHK6 Alpha-methylacyl-CoA racemase chr5 Not Cancer Driver No 1 hippie, biogrid 46 38 8 8 3
AOC3-201 AOC3 Q16853 Membrane primary amine oxidase chr17 Not Cancer Driver No 1 hippie 89 102 13 13 0
ARHGEF26-202 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 Not Cancer Driver No 1 hippie, biogrid 100 481 54 54 0
AUH-202 AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 29 0 0 1
AXL-201 AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 biogrid 131 342 51 51 0
BBS1-201 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 hippie 52 100 9 9 11
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BPNT1-201 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 32 9 0 0 0
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 5 5 2
C20orf96-201 C20orf96 Q9NUD7 Uncharacterized protein C20orf96 chr20 Not Cancer Driver No 1 hippie, biogrid 27 149 14 14 0
CBR4-201 CBR4 Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase chr4 Not Cancer Driver No 1 hippie, biogrid 13 4 0 0 0
CDIPT-201 CDIPT O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase chr16 Not Cancer Driver No 1 hippie 18 0 0 0 0
COL8A2-202 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 Not Cancer Driver No 1 hippie 12 561 4 4 4
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 38 13 2 2 0
CYB561-201 CYB561 P49447 Transmembrane ascorbate-dependent reductase CYB561 chr17 Not Cancer Driver No 1 hippie 22 6 0 0 1
DCP2-201 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 hippie 40 167 21 21 0
DNAJA3-201 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 44 152 19 19 0
DNAJC2-203 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 40 426 30 30 0
DPYSL5-201 DPYSL5 Q9BPU6 Dihydropyrimidinase-related protein 5 chr2 Not Cancer Driver No 1 hippie 115 116 20 20 2
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
ENST00000419755 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 hippie 52 132 7 7 11
EPHA8-201 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 hippie 156 122 16 16 0
ETFBKMT-201 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 Not Cancer Driver No 1 hippie 14 0 0 0 0
EXD2-214 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 47 178 12 12 0
FAHD1-203 FAHD1 Q6P587 Acylpyruvase FAHD1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 7 12 0 0 0
FBXO15-201 FBXO15 Q8NCQ5 F-box only protein 15 chr18 Not Cancer Driver No 1 hippie 63 0 0 0 0
FEM1A-201 FEM1A Q9BSK4 Protein fem-1 homolog A chr19 Not Cancer Driver No 1 hippie, biogrid 42 162 13 13 0
FETUB-201 FETUB Q9UGM5 Fetuin-B chr3 Not Cancer Driver No 1 hippie 56 124 28 28 0
FNTA-201 FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 Not Cancer Driver No 1 hippie, biogrid 29 92 9 9 0
FOXB1-201 FOXB1 Q99853 Forkhead box protein B1 chr15 Not Cancer Driver No 1 hippie 25 114 4 4 0
FOXH1-201 FOXH1 O75593 Forkhead box protein H1 chr8 Not Cancer Driver No 1 hippie 38 217 19 19 0
FOXI2-201 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 hippie 28 166 20 20 0
FOXL1-201 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 hippie 41 213 18 18 0
FOXL2-201 FOXL2 P58012 Forkhead box protein L2 chr3 Census, Compendium Yes 1 hippie 33 258 16 16 22
FSCN1-201 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 hippie 44 81 5 5 0
GAPDHS-201 GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 Not Cancer Driver No 2 hippie, biogrid 52 111 12 12 0
GCAT-201 GCAT O75600 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 46 2 0 0 0
GLYATL1-212 GLYATL1 Q969I3 Glycine N-acyltransferase-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 77 30 19 19 0
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 23 25 3 3 0
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 45 83 1 1 2
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KLHL20-201 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 Not Cancer Driver No 1 hippie, biogrid 64 144 12 12 0
LAMP3-201 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 2 hippie, biogrid 57 223 34 34 0
LCN1-202 LCN1 P31025 Lipocalin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 27 69 13 13 0
LDHAL6B-201 LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 37 17 1 1 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
MALSU1-202 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 17 34 1 1 0
MCUR1-201 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 66 0 0 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MRM2-201 MRM2 Q9UI43 rRNA methyltransferase 2, mitochondrial chr7 Not Cancer Driver No 1 hippie 33 15 1 1 1
MRPL12-201 MRPL12 P52815 Large ribosomal subunit protein bL12m chr17 Not Cancer Driver No 2 hippie, biogrid 16 22 4 4 1
MRPL21-201 MRPL21 Q7Z2W9 Large ribosomal subunit protein bL21m chr11 Not Cancer Driver No 1 hippie, biogrid 20 20 0 0 0
MRPS2-201 MRPS2 Q9Y399 Small ribosomal subunit protein uS2m chr9 Not Cancer Driver No 1 hippie, biogrid 26 57 4 4 3
MRPS24-201 MRPS24 Q96EL2 Small ribosomal subunit protein uS3m chr7 Not Cancer Driver No 1 hippie, biogrid 16 2 0 0 0
MRPS30-202 MRPS30 Q9NP92 Large ribosomal subunit protein mL65 chr5 Not Cancer Driver No 1 hippie, biogrid 42 53 7 7 0
MTG2-201 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 2 hippie, biogrid 43 48 7 7 0
MTIF2-201 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 114 7 7 0
MTRF1L-203 MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 17 185 5 5 0
MYL10-201 MYL10 Q9BUA6 Myosin regulatory light chain 10 chr7 Not Cancer Driver No 1 hippie, biogrid 30 50 4 4 0
NARS2-201 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 48 22 2 2 3
NDUFS7-201 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 30 31 2 2 1
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NIPSNAP3A-201 NIPSNAP3A Q9UFN0 Protein NipSnap homolog 3A chr9 Not Cancer Driver No 1 hippie, biogrid 18 15 4 4 0
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 25 169 19 19 0
OPTN-202 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 47 475 40 40 6
OXCT2-201 OXCT2 Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 38 56 3 3 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 32 49 7 7 0
PLAUR-203 PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 Not Cancer Driver No 1 hippie, biogrid 38 18 4 4 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLP2-202 PLP2 Q04941 Proteolipid protein 2 chrX Not Cancer Driver No 1 hippie 32 10 2 2 0
POR-218 POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie, biogrid 49 94 4 4 9
QRSL1-202 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 44 63 2 2 2
RASL10B-201 RASL10B Q96S79 Ras-like protein family member 10B chr17 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 20 117 12 12 0
SHC2-201 SHC2 P98077 SHC-transforming protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 50 367 37 37 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC25A10-202 SLC25A10 Q9UBX3 Mitochondrial dicarboxylate carrier chr17 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 6
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SYVN1-203 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 25 284 0 0 0
TERF2-201 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 26 361 15 15 0
THSD7B-201 THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 hippie 562 95 20 20 0
TMEM239-201 TMEM239 Q8WW34 Transmembrane protein 239 chr20 Not Cancer Driver No 1 hippie 0 27 0 0 0
TRAP1-201 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 110 6 6 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRIM43-201 TRIM43 Q96BQ3 Tripartite motif-containing protein 43 chr2 Not Cancer Driver No 1 hippie, biogrid 35 28 5 5 0
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 hippie 40 124 11 11 0
TRMU-223 TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 Not Cancer Driver No 1 hippie, biogrid 27 30 8 8 2
TSPAN33-201 TSPAN33 Q86UF1 Tetraspanin-33 chr7 Not Cancer Driver No 1 hippie 19 0 0 0 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UNC50-201 UNC50 Q53HI1 Protein unc-50 homolog chr2 Not Cancer Driver No 1 hippie 15 0 0 0 0
UQCRFS1-201 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 27 47 1 1 1
YARS2-201 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 47 63 8 8 2
YBEY-206 YBEY P58557 Endoribonuclease YbeY chr21 Not Cancer Driver No 2 hippie, biogrid 13 9 1 1 0
ZUP1-202 ZUP1 Q96AP4 Zinc finger-containing ubiquitin peptidase 1 chr6 Not Cancer Driver No 1 hippie 48 204 13 13 0