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DCLRE1B-203 ,DCLRE1B ,Q9H816
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 41
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APOE-201 APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 intact, hippie 20 124 5 5 10
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 intact, hippie 25 183 12 12 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 intact, hippie 167 1466 127 127 34
COMT-202 COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie 16 5 0 0 0
DCLRE1B-203 DCLRE1B Q9H816 5' exonuclease Apollo chr1 Not Cancer Driver No 1 intact, hippie 44 127 12 12 1
DNM2-201 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 95 271 32 32 16
ELAVL4-203 ELAVL4 P26378 ELAV-like protein 4 chr1 Not Cancer Driver No 1 intact, hippie 85 117 21 21 0
ENST00000640655 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie 92 721 45 45 0
FAM199X-202 FAM199X Q6PEV8 Protein FAM199X chrX Not Cancer Driver No 1 intact, hippie, biogrid 47 193 25 25 0
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FNBP1L-202 FNBP1L Q5T0N5 Formin-binding protein 1-like chr1 Not Cancer Driver No 1 intact, hippie 43 371 24 24 0
FSBP-201 FSBP O95073 Fibrinogen silencer-binding protein chr8 Not Cancer Driver No 1 intact, biogrid 6 145 3 3 0
GINS2-201 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 Not Cancer Driver No 1 hippie 15 38 4 4 0
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 45 83 1 1 2
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
KANSL2-201 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 Not Cancer Driver No 1 intact, hippie 38 306 19 19 0
MRE11-201 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 61 292 28 28 1
MUS81-201 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 Not Cancer Driver No 1 hippie 47 235 25 25 0
NDRG1-201 NDRG1 Q92597 Protein NDRG1 chr8 Census Yes 1 hippie 44 141 18 18 0
NOXA1-203 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 Not Cancer Driver No 1 intact, hippie 22 216 15 15 0
POT1-201 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 98 31 5 5 9
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 intact, hippie 385 421 43 43 2
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 intact, hippie 43 134 18 18 69
PSMD4-202 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 1 intact, hippie 31 243 19 19 0
RAD50-201 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie 106 730 50 50 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RPS27L-201 RPS27L Q71UM5 Ribosomal protein eS27-like chr15 Not Cancer Driver No 1 intact, hippie, biogrid 3 22 1 1 0
S100B-201 S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 8 14 0 0 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 435 19 19 0
SLC39A10-201 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 Not Cancer Driver No 1 intact, hippie 74 417 41 41 0
SLX4-201 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 hippie 201 1586 175 175 0
SPAG5-201 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 hippie 95 636 59 59 0
SPRED1-201 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 53 195 28 28 2
TDP1-201 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 Not Cancer Driver No 1 intact, hippie 64 179 20 20 1
TERF1-202 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 2 intact, hippie 51 221 32 32 0
TERF2-201 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 3 hippie, biogrid 26 361 15 15 0
TERF2IP-201 TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 3 hippie, biogrid 20 312 12 12 0
TFR2-201 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 Not Cancer Driver No 1 hippie 70 168 15 15 3
TINF2-201 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 intact, hippie 29 190 13 13 3
TRIM54-202 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 hippie, biogrid 47 98 11 11 0
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40
ZGPAT-201 ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 1 intact, hippie, biogrid 64 347 42 42 0