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DDOST-201 ,DDOST ,P39656
  • Number of Interaction partner in intact: 65
  • Number of Interaction partner in biogrid: 109
  • Number of Interaction partner in hippie: 242
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M-201 A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 203 144 20 20 0
ACADM-202 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 39 42 2 2 19
ACE2-201 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 67 68 4 4 0
ADCK2-201 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 46 9 1 1 0
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 intact, hippie 94 87 10 10 1
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact, hippie 91 142 12 12 10
AGO3-203 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 intact, hippie 93 143 18 18 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
AMFR-201 AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 Not Cancer Driver No 1 hippie 49 229 22 22 0
ANKRD55-201 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 72 340 48 48 0
ANPEP-201 ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 126 110 21 21 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 94 419 52 52 12
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ARHGAP19-202 ARHGAP19 Q14CB8 Rho GTPase-activating protein 19 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 47 179 16 16 0
ARHGAP19-SLIT1-202 ARHGAP19 Q14CB8 Rho GTPase-activating protein 19 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 47 191 16 16 0
ASB11-203 ASB11 Q8WXH4 Ankyrin repeat and SOCS box protein 11 chrX Not Cancer Driver No 1 hippie 32 7 1 1 0
ATF2-201 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 42 451 36 36 0
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 76 115 14 14 6
ATP5F1C-202 ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 27 11 0 0 0
ATP5F1D-201 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 Not Cancer Driver No 1 hippie 6 5 1 1 2
ATP5MG-201 ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 hippie 15 0 0 0 0
ATP6V1A-201 ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 65 31 0 0 4
ATP6V1B2-201 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie 38 49 3 3 1
AUP1-201 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 Not Cancer Driver No 1 hippie 29 122 9 9 0
AXL-201 AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 biogrid 131 342 51 51 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
BRCC3-204 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX Not Cancer Driver No 1 intact, hippie, biogrid 22 74 4 4 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 16 16 0
CALR3-201 CALR3 Q96L12 Calreticulin-3 chr19 Not Cancer Driver No 2 hippie, biogrid 42 103 15 15 0
CALU-201 CALU O43852 Calumenin chr7 Not Cancer Driver No 1 hippie, biogrid 15 130 9 9 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 2 intact, hippie, biogrid 57 334 36 36 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 40 34 2 2 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 216 145 9 9 130
CHD3-201 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 187 1017 92 92 17
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CLEC4D-201 CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 52 18 3 3 0
CLEC4E-201 CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 42 5 2 2 0
CLN3-243 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 hippie 42 69 5 5 8
CLN6-201 CLN6 Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 chr15 Not Cancer Driver No 1 intact, hippie 23 13 0 0 23
CLTC-201 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 132 71 5 5 1
CNR2-201 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 44 21 4 4 0
COP1-204 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 intact 81 148 5 5 0
COQ8A-201 COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 69 169 21 21 10
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 33 0 0 0 2
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 13 5 1 1 1
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie, biogrid 36 7 2 2 0
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
CTSS-201 CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 54 102 2 2 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
CUL9-201 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie 239 633 59 59 0
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 8
DDR2-201 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 Census Yes 1 biogrid 129 120 25 25 7
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX39A-201 DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 36 37 2 2 0
DDX39B-202 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie, biogrid 36 34 6 6 0
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie 17 12 0 0 0
DIABLO-207 DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 20 54 2 2 1
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 41 141 19 19 2
DNAJB12-203 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 28 227 11 11 0
DNAJB9-201 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 21 109 12 12 0
DNAJC10-201 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie, biogrid 77 37 3 3 0
DNAJC25-201 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 23 39 3 3 0
DNAJC3-202 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 40 131 13 13 0
DNAJC30-201 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 13 83 3 3 3
DPP4-201 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 108 8 0 0 0
DUSP9-201 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 33 109 12 12 0
DYRK4-211 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 86 178 25 25 0
EDEM1-201 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 44 141 5 5 0
EDEM3-201 EDEM3 Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 chr1 Not Cancer Driver No 1 hippie 76 304 29 29 0
EED-201 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 42 79 10 10 4
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EHD4-201 EHD4 Q9H223 EH domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 39 98 7 7 0
EIF6-203 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 22 17 2 2 0
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 77 61 4 4 2
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 38 29 2 2 0
ENST00000636766 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 hippie 0 0 0 0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPHA8-201 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 intact, biogrid 156 122 16 16 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
EXD2-214 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 47 178 12 12 0
FAF1-201 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 54 241 23 23 0
FAM20C-201 FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 21 188 1 1 8
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FANCI-202 FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 intact, hippie 103 130 15 15 2
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 92 231 26 26 69
FHIP2B-201 FHIP2B Q86V87 FHF complex subunit HOOK-interacting protein 2B chr8 Not Cancer Driver No 1 intact 46 140 10 10 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 50 161 19 19 0
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 289 1249 137 137 8
FURIN-201 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie, biogrid 72 283 30 30 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GSTK1-201 GSTK1 Q9Y2Q3 Glutathione S-transferase kappa 1 chr7 Not Cancer Driver No 1 hippie, biogrid 28 30 3 3 0
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 54 41 9 9 12
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 145 751 95 95 3
HDAC5-213 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 93 720 61 61 0
HLA-B-249 HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 49 169 18 18 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 70 489 49 49 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie, biogrid 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie, biogrid 70 255 29 29 0
HSP90B1-201 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 56 269 17 17 0
HSPA13-201 HSPA13 P48723 Heat shock 70 kDa protein 13 chr21 Not Cancer Driver No 1 hippie, biogrid 58 48 6 6 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 49 282 26 26 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IGBP1-202 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 intact, hippie 32 194 18 18 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
ILF2-201 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 24 92 2 2 0
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie, biogrid 30 72 7 7 0
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact, biogrid 139 282 37 37 63
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITFG1-201 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 50 18 3 3 0
JAGN1-202 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 16 13 3 3 5
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KLF16-201 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 12 206 7 7 0
KRTCAP2-201 KRTCAP2 Q8N6L1 Keratinocyte-associated protein 2 chr1 Not Cancer Driver No 1 hippie 5 4 0 0 0
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 36 94 8 8 0
LGALS3-201 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 9 133 0 0 0
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 46 65 13 13 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 402 91 13 13 20
LTB4R2-204 LTB4R2 Q9NPC1 Leukotriene B4 receptor 2 chr14 Not Cancer Driver No 1 intact, hippie 21 55 11 11 0
LTK-201 LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 1 intact, biogrid 63 301 17 17 0
MAGEA6-201 MAGEA6 P43360 Melanoma-associated antigen 6 chrX Not Cancer Driver No 1 hippie 56 104 15 15 0
MAGT1-204 MAGT1 Q9H0U3 Magnesium transporter protein 1 chrX Not Cancer Driver No 2 hippie, biogrid 51 0 0 0 1
MAPK15-201 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 Not Cancer Driver No 1 hippie, biogrid 66 236 32 32 0
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
METTL14-201 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 37 224 14 14 0
MGST1-205 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
MLEC-201 MLEC Q14165 Malectin chr12 Not Cancer Driver No 2 intact, hippie 30 51 3 3 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MTX1-202 MTX1 Q13505 Metaxin-1 chr1 Not Cancer Driver No 1 hippie, biogrid 14 221 5 5 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NCAPD3-212 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 145 305 35 35 1
NOP56-201 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie, biogrid 56 194 26 26 0
NPC1-201 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 113 25 0 0 135
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NRP1-206 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 112 212 25 25 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact, biogrid 214 56 15 15 3
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 49 38 2 2 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
NXT1-201 NXT1 Q9UKK6 NTF2-related export protein 1 chr20 Not Cancer Driver No 1 intact, hippie 10 0 0 0 0
OSTC-201 OSTC Q9NRP0 Oligosaccharyltransferase complex subunit OSTC chr4 Not Cancer Driver No 1 hippie 8 0 0 0 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
PAEP-208 PAEP P09466 Glycodelin chr9 Not Cancer Driver No 1 intact, hippie 16 3 0 0 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PER2-201 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 118 783 72 72 1
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 23 74 11 11 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PMAIP1-202 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
POC5-202 POC5 Q8NA72 Centrosomal protein POC5 chr5 Not Cancer Driver No 1 hippie 35 356 26 26 0
POMK-201 POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 40 30 7 7 3
PPT1-219 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 27 0 0 0 22
PRKCZ-201 PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie, biogrid 47 117 11 11 0
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 intact, hippie 43 134 18 18 69
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 425 76 5 5 37
PTP4A3-204 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 intact, hippie 27 3 0 0 0
PTPRH-202 PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 Not Cancer Driver No 1 hippie 175 479 63 63 0
PTPRN-201 PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 Not Cancer Driver No 1 intact, hippie 116 500 63 63 0
PTPRO-201 PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 155 137 28 28 0
PTPRU-201 PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 Not Cancer Driver No 1 hippie 186 325 48 48 0
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RB1CC1-201 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 150 579 56 56 0
RDH13-203 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 Not Cancer Driver No 1 hippie, biogrid 33 48 4 4 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RFXANK-201 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 intact, hippie, biogrid 13 122 4 4 1
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 32 12 3 3 0
RND2-202 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 17 54 4 4 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 Not Cancer Driver No 1 biogrid 32 43 2 2 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 biogrid 164 304 58 58 5
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 2 intact, hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 4 hippie, biogrid 48 26 3 3 0
SAP18-207 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie, biogrid 14 100 9 9 0
SBK2-202 SBK2 P0C263 Serine/threonine-protein kinase SBK2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 23 73 1 1 0
SCAMP3-201 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 35 130 21 21 0
SEC61A1-201 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 0 0 0 3
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SEC63-201 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 67 267 25 25 0
SLC15A3-201 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 47 44 1 1 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC25A3-215 SLC25A3 Q00325 Solute carrier family 25 member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 31 32 4 4 1
SLC25A5-201 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 hippie 26 0 0 0 0
SLC2A1-203 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 43 13 2 2 44
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SMYD3-214 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 Not Cancer Driver No 1 intact, hippie 48 2 0 0 0
SRSF11-201 SRSF11 Q05519 Serine/arginine-rich splicing factor 11 chr1 Not Cancer Driver No 1 hippie 25 362 19 19 0
SSR1-201 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 17 115 5 5 0
SSR3-201 SSR3 Q9UNL2 Translocon-associated protein subunit gamma chr3 Not Cancer Driver No 2 hippie, biogrid 20 18 5 5 0
SSR4-203 SSR4 P51571 Translocon-associated protein subunit delta chrX Not Cancer Driver No 2 hippie, biogrid 11 0 0 0 0
ST14-201 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 hippie, biogrid 86 47 5 5 1
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
STING1-201 STING1 Q86WV6 Stimulator of interferon genes protein chr5 Not Cancer Driver No 1 intact 39 66 12 12 4
STT3A-201 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 2 intact, hippie, biogrid 60 27 1 1 4
STT3B-201 STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 2 hippie, biogrid 48 136 8 8 0
STYXL1-203 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 Not Cancer Driver No 1 hippie 43 18 2 2 0
SUZ12-201 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 55 483 32 32 3
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
SYVN1-203 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 25 284 0 0 0
TCTN1-225 TCTN1 Q2MV58 Tectonic-1 chr12 Not Cancer Driver No 1 intact, hippie 56 47 6 6 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 62 23 2 2 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TECR-201 TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 1
TEX101-201 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 39 2 0 0 0
TGOLN2-201 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 39 401 33 33 0
TMBIM4-202 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 Not Cancer Driver No 1 hippie, biogrid 25 3 0 0 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMEM258-204 TMEM258 P61165 Transmembrane protein 258 chr11 Not Cancer Driver No 1 hippie 9 0 0 0 0
TMEM41B-204 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 16 48 2 2 0
TMPRSS11B-201 TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 77 5 0 0 0
TMPRSS2-201 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 47 25 3 3 0
TMPRSS4-201 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 41 34 1 1 0
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 38 111 14 14 9
TNFRSF1B-201 TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 40 231 21 21 0
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 11 83 5 5 0
TOMM40-203 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 15 98 0 0 0
TOMM5-201 TOMM5 Q8N4H5 Mitochondrial import receptor subunit TOM5 homolog chr9 Not Cancer Driver No 1 hippie, biogrid 2 0 0 0 0
TRIM13-202 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 Not Cancer Driver No 1 hippie 41 1 0 0 0
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 36 51 4 4 1
TYRO3-201 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 Not Cancer Driver No 1 intact, biogrid 86 197 18 18 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 64 581 61 61 8
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UGT2B7-201 UGT2B7 P16662 UDP-glucuronosyltransferase 2B7 chr4 Not Cancer Driver No 1 intact 89 6 0 0 0
UNC93B1-201 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 2 intact, hippie 42 127 3 3 0
UQCRB-201 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 1 hippie, biogrid 8 2 0 0 0
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 31 48 5 5 1
UQCRQ-203 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 8 12 1 1 1
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie, biogrid 20 184 11 11 0
VAPB-204 VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 2 hippie, biogrid 10 138 7 7 3
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 25 36 4 4 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 4 hippie, biogrid 22 9 1 1 0
VDAC3-201 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 2 hippie, biogrid 20 0 0 0 0
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 intact, hippie 67 316 45 45 1
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
XAB2-201 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 Not Cancer Driver No 1 intact, hippie 91 127 16 16 0
ZBTB2-201 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 64 216 29 29 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 36 929 33 33 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 46 23 0 0 3
ZNF598-202 ZNF598 Q86UK7 E3 ubiquitin-protein ligase ZNF598 chr16 Not Cancer Driver No 1 hippie 68 567 47 47 0