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DDR2-201 ,DDR2 ,Q16832
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 110
  • Number of Interaction partner in hippie: 25
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD3-202 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 biogrid 52 21 1 1 0
ABCE1-201 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 biogrid 50 36 4 4 0
ACOX3-201 ACOX3 O15254 Peroxisomal acyl-coenzyme A oxidase 3 chr4 Not Cancer Driver No 1 biogrid 79 26 5 5 0
AGFG1-201 AGFG1 P52594 Arf-GAP domain and FG repeat-containing protein 1 chr2 Not Cancer Driver No 1 biogrid 39 398 31 31 0
AHSG-202 AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 1 biogrid 61 132 33 33 0
ALDH3A2-201 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 biogrid 30 5 1 1 25
AP2M1-201 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 biogrid 40 41 7 7 1
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ASAP1-202 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 biogrid 132 587 79 79 0
ATAD3A-202 ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 Not Cancer Driver No 1 biogrid 49 275 16 16 2
ATAD3B-206 ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 biogrid 63 245 17 17 0
BAZ1B-201 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 Not Cancer Driver No 1 biogrid 104 841 61 61 0
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 biogrid 112 607 57 57 0
CBLB-201 CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 126 565 77 77 0
CDC25B-201 CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 biogrid 61 329 33 33 0
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 2 hippie, biogrid 43 214 29 29 0
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CDH2-201 CDH2 P19022 Cadherin-2 chr18 Not Cancer Driver No 2 hippie, biogrid 182 464 107 107 7
CHORDC1-201 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 2 hippie, biogrid 37 119 12 12 0
CKB-201 CKB P12277 Creatine kinase B-type chr14 Not Cancer Driver No 1 biogrid 23 102 3 3 0
CLU-201 CLU P10909 Clusterin chr8 Not Cancer Driver No 2 biogrid 43 157 18 18 0
COL11A2-201 COL11A2 P13942 Collagen alpha-2(XI) chain chr6 Not Cancer Driver No 1 hippie 99 1471 77 77 7
COL1A1-201 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie 36 1213 10 10 140
COL3A1-201 COL3A1 P02461 Collagen alpha-1(III) chain chr2 Census Yes 1 hippie 49 1183 6 6 86
CPD-201 CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 biogrid 90 476 33 33 0
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 biogrid 90 268 25 25 4
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 biogrid 363 288 291 291 11
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 98 168 18 18 3
CYP7B1-201 CYP7B1 O75881 Cytochrome P450 7B1 chr8 Not Cancer Driver No 1 biogrid 103 0 0 0 10
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 biogrid 20 13 3 3 1
DDR1-225 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 2 hippie, biogrid 98 253 41 41 0
DHX9-201 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 biogrid 125 332 30 30 0
DMPK-201 DMPK Q09013 Myotonin-protein kinase chr19 Not Cancer Driver No 1 biogrid 42 220 12 12 0
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 biogrid 41 141 19 19 2
DNAJC3-202 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 biogrid 40 131 13 13 0
DNAJC9-201 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 biogrid 17 126 8 8 0
DPM1-203 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 Not Cancer Driver No 1 biogrid 24 29 1 1 3
DSC1-202 DSC1 Q08554 Desmocollin-1 chr18 Not Cancer Driver No 1 biogrid 161 268 53 53 0
DSC3-201 DSC3 Q14574 Desmocollin-3 chr18 Not Cancer Driver No 1 biogrid 158 214 45 45 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
EPCAM-201 EPCAM P16422 Epithelial cell adhesion molecule chr2 Not Cancer Driver No 1 biogrid 27 26 1 1 1
FAM120A-201 FAM120A Q9NZB2 Constitutive coactivator of PPAR-gamma-like protein 1 chr9 Not Cancer Driver No 1 biogrid 85 517 40 40 0
FKBP4-201 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 biogrid 39 134 11 11 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 biogrid 50 161 19 19 0
FLG-201 FLG P20930 Filaggrin chr1 Not Cancer Driver No 1 biogrid 1351 4059 1373 1373 0
FOXK1-201 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 2 biogrid 68 514 46 46 0
FOXK2-201 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 biogrid 65 550 55 55 0
GLUD1-201 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 Not Cancer Driver No 1 biogrid 34 109 9 9 10
GOLT1B-201 GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 hippie 14 0 0 0 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 biogrid 21 10 0 0 0
HADHA-201 HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 biogrid 52 19 0 0 5
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 biogrid 54 41 9 9 12
HAVCR1-203 HAVCR1 Q96D42 Hepatitis A virus cellular receptor 1 chr5 Not Cancer Driver No 1 hippie 21 150 0 0 0
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 biogrid 517 971 113 113 1
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 biogrid 38 125 16 16 0
HNRNPUL2-201 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 biogrid 56 419 29 29 0
HNRNPUL2-BSCL2-201 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 biogrid 56 421 29 29 0
HSD17B10-201 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 biogrid 18 15 3 3 11
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 hippie, biogrid 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 hippie, biogrid 70 255 29 29 0
HYOU1-218 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 biogrid 98 373 36 36 0
INPPL1-201 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 1 biogrid 146 567 66 66 4
JPH1-201 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 biogrid 102 422 67 67 0
KPRP-201 KPRP Q5T749 Keratinocyte proline-rich protein chr1 Not Cancer Driver No 1 biogrid 162 196 52 52 0
KTN1-205 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 biogrid 93 969 66 66 0
LGALS3BP-201 LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 biogrid 49 9 0 0 0
MAGT1-204 MAGT1 Q9H0U3 Magnesium transporter protein 1 chrX Not Cancer Driver No 1 biogrid 51 0 0 0 1
MAP7D1-204 MAP7D1 Q3KQU3 MAP7 domain-containing protein 1 chr1 Not Cancer Driver No 1 biogrid 62 823 58 58 0
MSMO1-201 MSMO1 Q15800 Methylsterol monooxygenase 1 chr4 Not Cancer Driver No 1 biogrid 26 4 0 0 2
MTHFD1-220 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 biogrid 78 129 11 11 6
NDUFA4-201 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 biogrid 8 4 0 0 0
NEK4-201 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 55 495 40 40 0
NEURL4-202 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 biogrid 145 753 83 83 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 biogrid 214 56 15 15 3
OSBPL8-201 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 Not Cancer Driver No 1 biogrid 79 402 31 31 0
P4HA1-204 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 biogrid 47 54 3 3 0
PCDH7-201 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 biogrid 133 553 64 64 0
PEAK1-213 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 1 biogrid 175 1233 119 119 0
PFKL-201 PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 biogrid 68 29 2 2 0
PIK3CB-214 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 1 biogrid 112 42 3 3 0
PLD1-201 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 biogrid 126 133 21 21 1
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 biogrid 71 98 5 5 0
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 biogrid 385 421 43 43 2
PTP4A3-204 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 biogrid 27 3 0 0 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 biogrid 36 141 17 17 0
RAB11FIP5-201 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 biogrid 52 533 44 44 0
RAB21-201 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 Not Cancer Driver No 1 biogrid 15 59 4 4 0
RAB8A-201 RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 biogrid 30 26 3 3 0
RAB9A-202 RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 biogrid 7 21 0 0 0
RBM28-201 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 biogrid 71 513 51 51 1
RFC3-201 RFC3 P40938 Replication factor C subunit 3 chr13 Not Cancer Driver No 1 biogrid 22 13 1 1 0
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 50 20 1 1 0
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 biogrid 48 26 3 3 0
SEC23A-201 SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 biogrid 66 73 5 5 1
SEC23B-211 SEC23B Q15437 Protein transport protein Sec23B chr20 Not Cancer Driver No 1 biogrid 72 82 4 4 7
SEC24A-202 SEC24A O95486 Protein transport protein Sec24A chr5 Not Cancer Driver No 1 biogrid 71 409 38 38 0
SEC24B-201 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 1 biogrid 102 526 41 41 0
SEC61A1-201 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 Not Cancer Driver No 1 biogrid 39 0 0 0 3
SERPINH1-201 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 biogrid 45 53 5 5 1
SGPL1-202 SGPL1 O95470 Sphingosine-1-phosphate lyase 1 chr10 Not Cancer Driver No 1 biogrid 46 19 3 3 2
SHC1-202 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 58 400 41 41 0
SLC25A1-201 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 biogrid 17 34 1 1 15
SLC25A13-201 SLC25A13 Q9UJS0 Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial chr7 Not Cancer Driver No 1 biogrid 73 23 2 2 1
SLC25A5-201 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 biogrid 26 0 0 0 0
SLC2A1-203 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 biogrid 43 13 2 2 44
SPRR2E-201 SPRR2E P22531 Small proline-rich protein 2E chr1 Not Cancer Driver No 1 biogrid 0 0 0 0 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 biogrid 20 0 0 0 6
STIM1-201 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 biogrid 55 386 35 35 12
STT3B-201 STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 biogrid 48 136 8 8 0
STX12-201 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 1 biogrid 13 156 6 6 0
TECR-201 TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 biogrid 33 0 0 0 1
TFRC-201 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 biogrid 66 80 4 4 1
TIMM44-201 TIMM44 O43615 Mitochondrial import inner membrane translocase subunit TIM44 chr19 Not Cancer Driver No 1 biogrid 38 175 17 17 0
TK1-201 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 biogrid 19 13 3 3 0
TST-201 TST Q16762 Thiosulfate sulfurtransferase chr22 Not Cancer Driver No 1 biogrid 22 56 5 5 0
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 biogrid 20 184 11 11 0
VAPB-204 VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 1 biogrid 10 138 7 7 3
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VMP1-201 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 39 68 7 7 0
WDR6-220 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 biogrid 128 105 9 9 0
ZFYVE9-201 ZFYVE9 O95405 Zinc finger FYVE domain-containing protein 9 chr1 Not Cancer Driver No 1 biogrid 123 670 68 68 0
ZNF146-201 ZNF146 Q15072 Zinc finger protein OZF chr19 Not Cancer Driver No 1 biogrid 25 44 2 2 0
ZNF260-202 ZNF260 Q3ZCT1 Zinc finger protein 260 chr19 Not Cancer Driver No 1 biogrid 41 91 7 7 0