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DIRAS3-202 ,DIRAS3 ,O95661
  • Number of Interaction partner in intact: 13
  • Number of Interaction partner in biogrid: 232
  • Number of Interaction partner in hippie: 256
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCC1-202 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 123 18 18 1
ADCY9-201 ADCY9 O60503 Adenylate cyclase type 9 chr16 Not Cancer Driver No 1 hippie, biogrid 137 272 32 32 0
ADD3-202 ADD3 Q9UEY8 Gamma-adducin chr10 Not Cancer Driver No 1 hippie, biogrid 66 381 33 33 1
ADGRL2-210 ADGRL2 O95490 Adhesion G protein-coupled receptor L2 chr1 Not Cancer Driver No 1 hippie 259 452 79 79 0
AFG3L2-201 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 38 162 5 5 17
ALCAM-201 ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 1 hippie, biogrid 66 97 12 12 0
ANK3-201 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 652 3069 442 442 0
ANKRD26-201 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 hippie, biogrid 156 1279 115 115 0
APC-201 APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 intact, hippie 295 2412 248 248 22
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 22 4 2 2 2
ARHGAP1-201 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 29 91 6 6 0
ARHGAP21-202 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie, biogrid 168 1613 140 140 0
ATG14-201 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 Not Cancer Driver No 1 hippie 43 209 23 23 0
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 76 115 14 14 6
ATP2B1-202 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 103 294 30 30 9
ATP5F1B-201 ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 85 7 7 1
ATP7A-201 ATP7A Q04656 Copper-transporting ATPase 1 chrX Not Cancer Driver No 1 hippie, biogrid 152 171 36 36 48
ATPAF1-211 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 24 47 4 4 0
BAG4-201 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 intact, hippie 40 402 36 36 0
BASP1-201 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 12 227 12 12 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 36 190 15 15 0
BRMS1-201 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 Not Cancer Driver No 1 intact, hippie 28 115 15 15 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 16 16 0
C2CD4C-201 C2CD4C Q8TF44 C2 calcium-dependent domain-containing protein 4C chr19 Not Cancer Driver No 1 hippie, biogrid 7 318 6 6 0
CACHD1-206 CACHD1 Q5VU97 VWFA and cache domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 124 206 25 25 0
CACYBP-201 CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 22 92 10 10 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
CBARP-207 CBARP Q8N350 Voltage-dependent calcium channel beta subunit-associated regulatory protein chr19 Not Cancer Driver No 1 hippie 34 665 29 29 0
CBX6-202 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 1 hippie, biogrid 43 336 41 41 0
CCDC88A-207 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 hippie, biogrid 145 1481 114 114 0
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie, biogrid 43 214 29 29 0
CDC42BPA-201 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 hippie, biogrid 143 718 55 55 0
CDC42EP1-201 CDC42EP1 Q00587 Cdc42 effector protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 23 371 18 18 0
CDCA3-207 CDCA3 Q99618 Cell division cycle-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 20 268 20 20 0
CEMIP2-202 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 Not Cancer Driver No 1 hippie 154 230 19 19 0
CEP89-201 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie, biogrid 67 542 44 44 0
CHEK2-206 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 72 157 19 19 11
CNNM3-201 CNNM3 Q8NE01 Metal transporter CNNM3 chr2 Not Cancer Driver No 1 hippie, biogrid 36 101 5 5 0
CNP-202 CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 Not Cancer Driver No 1 hippie, biogrid 21 71 1 1 0
CPD-201 CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie, biogrid 90 476 33 33 0
CPNE8-201 CPNE8 Q86YQ8 Copine-8 chr12 Not Cancer Driver No 1 hippie, biogrid 69 40 7 7 0
CTNND1-205 CTNND1 O60716 Catenin delta-1 chr11 Census Yes 1 hippie, biogrid 108 571 63 63 0
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
DCAF10-202 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 33 201 7 7 0
DEPDC1B-201 DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 1 hippie, biogrid 54 52 3 3 0
DLG1-269 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 89 460 48 48 0
DLG5-201 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie, biogrid 184 1119 107 107 0
DSC2-202 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 hippie, biogrid 146 257 42 42 5
DSG2-201 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie, biogrid 126 479 52 52 5
DST-241 DST Q03001 Dystonin chr6 Not Cancer Driver No 1 hippie, biogrid 512 3227 171 171 0
DTNA-205 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie, biogrid 107 412 58 58 0
ECPAS-207 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 119 243 14 14 0
EFNB1-201 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie, biogrid 35 126 10 10 14
EFNB2-202 EFNB2 P52799 Ephrin-B2 chr13 Not Cancer Driver No 1 hippie, biogrid 37 99 11 11 0
EFR3A-201 EFR3A Q14156 Protein EFR3 homolog A chr8 Not Cancer Driver No 1 hippie, biogrid 84 77 6 6 0
EFR3B-204 EFR3B Q9Y2G0 Protein EFR3 homolog B chr2 Not Cancer Driver No 1 hippie, biogrid 30 104 3 3 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 346 223 30 30 1
ELMOD3-203 ELMOD3 Q96FG2 ELMO domain-containing protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 29 58 4 4 2
ENST00000498285 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 3 60 1 1 3
EPB41L1-202 EPB41L1 Q9H4G0 Band 4.1-like protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 125 579 93 93 1
EPB41L2-201 EPB41L2 O43491 Band 4.1-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 125 709 91 91 0
EPB41L4A-201 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie, biogrid 77 380 41 41 0
EPB41L5-201 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 68 315 32 32 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie, biogrid 147 188 33 33 3
EPHA7-202 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 hippie, biogrid 226 71 10 10 0
EPN2-201 EPN2 O95208 Epsin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 58 544 48 48 0
ESYT2-202 ESYT2 A0FGR8 Extended synaptotagmin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 70 313 21 21 0
F11R-202 F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie, biogrid 42 72 12 12 0
FAM135A-205 FAM135A Q9P2D6 Protein FAM135A chr6 Not Cancer Driver No 1 hippie, biogrid 118 571 37 37 0
FAM83B-201 FAM83B Q5T0W9 Protein FAM83B chr6 Not Cancer Driver No 1 hippie, biogrid 239 691 172 172 0
FAM91A1-201 FAM91A1 Q658Y4 Protein FAM91A1 chr8 Not Cancer Driver No 1 hippie, biogrid 86 109 3 3 0
FARP1-201 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 105 314 44 44 0
FCHO2-202 FCHO2 Q0JRZ9 F-BAR domain only protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 45 375 22 22 0
FERMT2-201 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie, biogrid 44 102 8 8 0
FEZ2-204 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 11 248 6 6 0
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact, hippie 101 163 27 27 0
FKBP4-201 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 39 134 11 11 0
FLOT2-202 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 52 20 2 2 0
FLVCR1-201 FLVCR1 Q9Y5Y0 Heme transporter FLVCR1 chr1 Not Cancer Driver No 1 hippie, biogrid 38 117 5 5 5
FMN2-201 FMN2 Q9NZ56 Formin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 222 1327 218 218 0
FRS2-206 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 1 hippie, biogrid 54 417 46 46 0
GAB1-201 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 54 570 46 46 1
GLMN-201 GLMN Q92990 Glomulin chr1 Not Cancer Driver No 1 hippie, biogrid 40 37 6 6 0
GOLGA3-202 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 181 1283 156 156 0
GOLGA4-202 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 145 1663 105 105 0
GOPC-202 GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie, biogrid 40 263 27 27 0
GPRIN3-202 GPRIN3 Q6ZVF9 G protein-regulated inducer of neurite outgrowth 3 chr4 Not Cancer Driver No 1 hippie, biogrid 112 757 109 109 0
HECTD1-201 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie, biogrid 210 992 85 85 0
HERC1-201 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie, biogrid 350 1353 102 102 1
HGS-201 HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie, biogrid 83 535 62 62 0
HIP1-201 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie, biogrid 118 514 60 60 0
HIP1R-201 HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 Not Cancer Driver No 1 hippie, biogrid 73 527 30 30 0
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie, biogrid 38 125 16 16 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie, biogrid 263 2091 107 107 20
IGF2R-201 IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 233 257 13 13 0
ILDR2-201 ILDR2 Q71H61 Immunoglobulin-like domain-containing receptor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 94 356 43 43 0
IPO5-230 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 1 hippie, biogrid 82 52 2 2 0
IPO7-201 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 108 202 25 25 0
IPO8-201 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 hippie, biogrid 93 111 10 10 3
IRS4-202 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie, biogrid 98 801 80 80 0
ITGA2-201 ITGA2 P17301 Integrin alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 116 26 0 0 0
ITGA6-206 ITGA6 P23229 Integrin alpha-6 chr2 Not Cancer Driver No 1 hippie, biogrid 88 226 20 20 0
ITGB1-201 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie, biogrid 73 84 8 8 0
JUP-203 JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie, biogrid 81 242 24 24 0
KCNB2-201 KCNB2 Q92953 Potassium voltage-gated channel subfamily B member 2 chr8 Not Cancer Driver No 1 hippie, biogrid 323 503 181 181 0
KIAA1549-201 KIAA1549 Q9HCM3 UPF0606 protein KIAA1549 chr7 Census Yes 1 hippie, biogrid 213 1135 136 136 0
KIDINS220-201 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie, biogrid 166 684 78 78 0
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 hippie, biogrid 187 634 82 82 1
KIRREL1-201 KIRREL1 Q96J84 Kin of IRRE-like protein 1 chr1 Not Cancer Driver No 1 hippie 112 273 44 44 1
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie 771 7 2 2 22
LEMD3-201 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 1 hippie, biogrid 46 511 19 19 0
LLGL1-201 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie, biogrid 78 266 9 9 0
LMNB1-201 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 407 27 27 4
LNPEP-201 LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie, biogrid 80 103 5 5 0
LRBA-201 LRBA P50851 Lipopolysaccharide-responsive and beige-like anchor protein chr4 Not Cancer Driver No 1 hippie, biogrid 242 711 53 53 1
LRRC49-201 LRRC49 Q8IUZ0 Leucine-rich repeat-containing protein 49 chr15 Not Cancer Driver No 1 hippie, biogrid 82 124 15 15 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LSR-214 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie, biogrid 71 330 37 37 0
LTV1-201 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 31 391 20 20 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie, biogrid 63 511 51 51 0
MAGED2-206 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie, biogrid 72 328 38 38 1
MAP3K21-203 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 1 hippie 146 665 92 92 0
MAP3K9-205 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 Not Cancer Driver No 1 hippie, biogrid 134 685 85 85 0
MAP4K4-202 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 60 648 29 29 0
MAP4K5-210 MAP4K5 Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 chr14 Not Cancer Driver No 1 hippie, biogrid 54 237 19 19 0
MARK2-204 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 84 445 52 52 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 64 376 38 38 1
MARVELD2-201 MARVELD2 Q8N4S9 MARVEL domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 56 250 29 29 0
MCAM-201 MCAM P43121 Cell surface glycoprotein MUC18 chr11 Not Cancer Driver No 1 hippie, biogrid 63 310 29 29 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie, biogrid 39 298 24 24 0
MEOX2-201 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 59 275 53 53 0
MPP1-202 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX Not Cancer Driver No 1 hippie, biogrid 58 194 29 29 0
MPP7-209 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 1 hippie, biogrid 105 199 60 60 0
MPZL1-201 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 33 56 6 6 0
MTIF2-201 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 71 114 7 7 0
NAP1L1-226 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 2 hippie, biogrid 31 207 18 18 0
NAP1L4-201 NAP1L4 Q99733 Nucleosome assembly protein 1-like 4 chr11 Not Cancer Driver No 1 hippie, biogrid 18 194 7 7 0
NBEA-203 NBEA Q8NFP9 Neurobeachin chr13 Census, Compendium Yes 1 hippie, biogrid 397 719 102 102 4
NBR1-206 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 88 562 41 41 0
NECTIN2-201 NECTIN2 Q92692 Nectin-2 chr19 Not Cancer Driver No 1 hippie 44 296 18 18 0
NISCH-201 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 127 421 33 33 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie, biogrid 312 690 71 71 3
NOTCH2-201 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 191 631 61 61 1
NSFL1C-201 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie, biogrid 33 267 22 22 0
NUDCD3-202 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 22 199 12 12 0
NUMB-213 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie, biogrid 50 489 42 42 0
NUMBL-201 NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 34 468 20 20 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie, biogrid 41 80 13 13 1
PACSIN2-201 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 39 303 19 19 0
PAK4-203 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie, biogrid 46 344 27 27 0
PALB2-201 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 Census Yes 1 intact, hippie 95 772 56 56 1
PALM-202 PALM O75781 Paralemmin-1 chr19 Not Cancer Driver No 1 hippie, biogrid 40 384 40 40 0
PALM2AKAP2-206 PALM2 Q8IXS6 Paralemmin-2 chr9 Not Cancer Driver No 1 hippie, biogrid 49 334 43 43 0
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 148 1147 128 128 2
PCDH7-201 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 hippie, biogrid 133 553 64 64 0
PCNX3-201 PCNX3 Q9H6A9 Pecanex-like protein 3 chr11 Not Cancer Driver No 1 hippie 151 845 61 61 0
PEAK1-213 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 1 hippie, biogrid 175 1233 119 119 0
PEX19-201 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 26 267 23 23 0
PICALM-202 PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 Census Yes 1 hippie, biogrid 64 320 31 31 0
PIK3C3-201 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 Not Cancer Driver No 1 hippie 101 192 28 28 0
PKP2-201 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 139 435 77 77 8
PKP4-202 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie, biogrid 129 760 92 92 0
PLCH1-202 PLCH1 Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 chr3 Not Cancer Driver No 1 hippie, biogrid 295 774 144 144 0
PLEKHA1-203 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 48 192 28 28 0
PLEKHA5-201 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie, biogrid 115 870 89 89 0
PPFIA1-201 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie, biogrid 118 865 96 96 0
PPFIBP1-202 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie, biogrid 72 557 42 42 0
PPM1D-201 PPM1D O15297 Protein phosphatase 1D chr17 Census, Compendium Yes 1 hippie 32 370 17 17 0
PPM1G-201 PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie, biogrid 35 359 28 28 0
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie, biogrid 19 23 3 3 0
PSD3-202 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 86 650 56 56 0
PSMC1-201 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 hippie, biogrid 29 165 8 8 0
PSMC3-201 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie, biogrid 38 131 8 8 0
PSMD1-201 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie, biogrid 77 201 14 14 0
PSMD2-201 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 hippie, biogrid 71 136 11 11 0
PSMD4-202 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 1 hippie, biogrid 31 243 19 19 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 intact, hippie 36 141 17 17 0
PTPN13-202 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie, biogrid 213 1235 110 110 0
PTPRG-203 PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 hippie, biogrid 153 466 44 44 0
RAB23-202 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 Not Cancer Driver No 1 hippie, biogrid 17 61 6 6 2
RAB7A-201 RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 19 11 0 0 4
RALGAPA1-203 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 Not Cancer Driver No 1 hippie, biogrid 150 649 53 53 1
RAP1GDS1-205 RAP1GDS1 P52306 Rap1 GTPase-GDP dissociation stimulator 1 chr4 Census, Compendium Yes 1 hippie, biogrid 69 13 0 0 0
RASAL2-203 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 1 hippie, biogrid 134 607 69 69 0
RBM11-201 RBM11 P57052 Splicing regulator RBM11 chr21 Not Cancer Driver No 1 hippie, biogrid 47 125 23 23 0
RELL1-202 RELL1 Q8IUW5 RELT-like protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 202 7 7 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie, biogrid 92 46 12 12 2
RICTOR-202 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie, biogrid 144 365 34 34 0
RNF19B-203 RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 3 hippie, biogrid 45 344 20 20 0
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie, biogrid 164 304 58 58 5
SCAMP1-207 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 24 118 11 11 0
SCAMP3-201 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 35 130 21 21 0
SCARB1-203 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 6 0 0 0
SCRIB-201 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie, biogrid 169 1071 117 117 2
SCYL2-201 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 77 326 26 26 0
SEMA4C-201 SEMA4C Q9C0C4 Semaphorin-4C chr2 Not Cancer Driver No 1 hippie, biogrid 81 149 15 15 0
SLC12A2-201 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 97 297 13 13 8
SLC12A4-201 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 Not Cancer Driver No 1 hippie, biogrid 100 172 10 10 0
SLC12A7-201 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 Not Cancer Driver No 1 hippie, biogrid 126 202 23 23 0
SLC19A1-201 SLC19A1 P41440 Reduced folate transporter chr21 Not Cancer Driver No 1 hippie, biogrid 54 145 5 5 0
SLC1A5-203 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie, biogrid 42 61 7 7 0
SLC29A1-206 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 38 27 3 3 0
SLC30A1-201 SLC30A1 Q9Y6M5 Proton-coupled zinc antiporter SLC30A1 chr1 Not Cancer Driver No 3 hippie, biogrid 44 144 9 9 0
SLC38A1-201 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid symporter 1 chr12 Not Cancer Driver No 1 hippie, biogrid 70 25 3 3 0
SLC38A2-201 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid symporter 2 chr12 Not Cancer Driver No 1 hippie, biogrid 42 9 1 1 0
SLC39A10-201 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 Not Cancer Driver No 1 hippie, biogrid 74 417 41 41 0
SLC39A14-204 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 Not Cancer Driver No 1 hippie, biogrid 27 42 3 3 4
SLC39A6-201 SLC39A6 Q13433 Zinc transporter ZIP6 chr18 Not Cancer Driver No 1 hippie, biogrid 63 362 28 28 0
SLC3A2-203 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 44 171 7 7 0
SLC4A7-201 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie, biogrid 105 405 37 37 0
SLC6A15-201 SLC6A15 Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 chr12 Not Cancer Driver No 1 hippie, biogrid 119 70 13 13 0
SLC6A6-210 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 Not Cancer Driver No 1 hippie, biogrid 61 22 1 1 2
SLC6A8-201 SLC6A8 P48029 Sodium- and chloride-dependent creatine transporter 1 chrX Not Cancer Driver No 1 hippie, biogrid 36 25 1 1 12
SLC7A1-201 SLC7A1 P30825 High affinity cationic amino acid transporter 1 chr13 Not Cancer Driver No 1 hippie, biogrid 73 17 3 3 0
SLC7A2-204 SLC7A2 P52569 Cationic amino acid transporter 2 chr8 Not Cancer Driver No 1 hippie, biogrid 74 37 5 5 0
SLC7A5-201 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 Not Cancer Driver No 1 hippie, biogrid 48 35 0 0 0
SLC9A1-201 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 Not Cancer Driver No 1 hippie, biogrid 57 252 17 17 1
SNAP23-201 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie, biogrid 12 180 10 10 0
SNX6-201 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie, biogrid 22 86 4 4 0
SPECC1-204 SPECC1 Q5M775 Cytospin-B chr17 Census Yes 1 hippie, biogrid 111 838 91 91 0
SPTAN1-202 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 236 983 84 84 0
SPTBN1-202 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 218 877 86 86 16
SPTBN2-208 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 Not Cancer Driver No 1 hippie, biogrid 233 879 90 90 2
STAM2-201 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie, biogrid 49 292 25 25 0
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 93 152 16 16 15
STEAP3-201 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 Not Cancer Driver No 1 hippie, biogrid 72 30 4 4 0
TBC1D10B-201 TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 Not Cancer Driver No 1 hippie, biogrid 36 498 20 20 0
TBC1D8-201 TBC1D8 O95759 TBC1 domain family member 8 chr2 Not Cancer Driver No 1 hippie, biogrid 109 223 19 19 0
TC2N-203 TC2N Q8N9U0 Tandem C2 domains nuclear protein chr14 Not Cancer Driver No 1 hippie, biogrid 64 119 18 18 0
TFRC-201 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 66 80 4 4 1
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 intact, hippie 30 44 3 3 8
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 1 hippie, biogrid 263 813 147 147 0
TMEM51-201 TMEM51 Q9NW97 Transmembrane protein 51 chr1 Not Cancer Driver No 1 hippie, biogrid 38 187 30 30 0
TMEM87A-202 TMEM87A Q8NBN3 Transmembrane protein 87A chr15 Not Cancer Driver No 1 hippie, biogrid 46 71 6 6 0
TOR1AIP1-212 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 53 400 33 33 0
TPD52L2-202 TPD52L2 O43399 Tumor protein D54 chr20 Not Cancer Driver No 1 hippie, biogrid 17 180 16 16 0
TPGS1-201 TPGS1 Q6ZTW0 Tubulin polyglutamylase complex subunit 1 chr19 Not Cancer Driver No 1 hippie, biogrid 2 64 0 0 0
TRPM7-210 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 Not Cancer Driver No 1 hippie, biogrid 133 456 37 37 1
TUBAL3-201 TUBAL3 A6NHL2 Tubulin alpha chain-like 3 chr10 Not Cancer Driver No 1 hippie, biogrid 59 25 2 2 0
TUBB2B-201 TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie, biogrid 33 68 4 4 10
TXNL1-201 TXNL1 O43396 Thioredoxin-like protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 19 90 3 3 0
UBXN4-201 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 53 303 32 32 0
USP6NL-205 USP6NL Q92738 USP6 N-terminal-like protein chr10 Not Cancer Driver No 1 hippie, biogrid 79 469 56 56 0
VAMP2-201 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 3 47 0 0 3
VAMP3-201 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 8 17 1 1 0
VANGL1-202 VANGL1 Q8TAA9 Vang-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 55 142 9 9 3
VANGL2-201 VANGL2 Q9ULK5 Vang-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 79 150 13 13 3
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 74 186 14 14 12
VPS45-214 VPS45 Q9NRW7 Vacuolar protein sorting-associated protein 45 chr1 Not Cancer Driver No 1 hippie, biogrid 47 58 3 3 2
WDR6-220 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 128 105 9 9 0
XPR1-202 XPR1 Q9UBH6 Solute carrier family 53 member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 76 70 10 10 7
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 48 63 9 9 0
YKT6-201 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 1 hippie, biogrid 11 21 1 1 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie, biogrid 66 463 46 46 0