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DNAJB4-201 ,DNAJB4 ,Q9UDY4
  • Number of Interaction partner in intact: 37
  • Number of Interaction partner in biogrid: 76
  • Number of Interaction partner in hippie: 128
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD15-201 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 42 42 2 2 0
AHSA1-201 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 2 hippie, biogrid 33 147 14 14 0
AKAP10-201 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 36 306 14 14 0
ANGPTL4-201 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 47 180 23 23 0
ANK2-202 ANK2 Q01484 Ankyrin-2 chr4 Not Cancer Driver No 1 hippie, biogrid 597 2850 428 428 4
APOBEC3D-201 APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 intact, hippie, biogrid 28 3 0 0 0
ARGLU1-203 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 20 246 14 14 0
ASB4-202 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 Not Cancer Driver No 1 hippie 60 19 1 1 0
ATP5PO-201 ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 17 9 2 2 0
ATXN1-202 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 intact, hippie 111 608 91 91 0
BAG1-210 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 intact, hippie 19 197 5 5 0
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 2 hippie, biogrid 13 112 7 7 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 2 hippie, biogrid 27 63 5 5 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
C3orf38-201 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 28 50 5 5 0
CARD8-231 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 41 130 5 5 1
CBX5-201 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie, biogrid 15 116 8 8 0
CCDC138-201 CCDC138 Q96M89 Coiled-coil domain-containing protein 138 chr2 Not Cancer Driver No 1 hippie, biogrid 49 203 18 18 0
CCDC61-204 CCDC61 Q9Y6R9 Centrosomal protein CCDC61 chr19 Not Cancer Driver No 1 hippie, biogrid 20 349 8 8 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CRMP1-202 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie 102 96 12 12 0
DET1-201 DET1 Q7L5Y6 DET1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 79 42 9 9 0
DNAJB1-201 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 4 intact, hippie, biogrid 26 196 20 20 0
DNAJB5-210 DNAJB5 O75953 DnaJ homolog subfamily B member 5 chr9 Not Cancer Driver No 4 hippie, biogrid 35 147 12 12 0
DNAJB6-201 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 4 198 2 2 3
DNAJC7-203 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 intact, hippie 26 102 8 8 0
ECPAS-207 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 119 243 14 14 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EIF4H-201 EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 Not Cancer Driver No 1 hippie, biogrid 21 175 12 12 0
ENST00000381568 APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 intact, hippie, biogrid 28 3 0 0 0
ENST00000649547 DET1 Q7L5Y6 DET1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 79 42 9 9 0
ERCC8-218 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 Not Cancer Driver No 1 hippie 17 55 7 7 6
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
ETF1-201 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 hippie, biogrid 36 28 5 5 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
GLB1-201 GLB1 P16278 Beta-galactosidase chr3 Not Cancer Driver No 2 intact, hippie, biogrid 58 44 6 6 89
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 21 10 0 0 0
GRPEL1-201 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 13 88 5 5 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 19 200 7 7 0
HSPA1L-201 HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 86 141 23 23 0
HSPA2-201 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 68 286 30 30 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 2 hippie, biogrid 50 352 21 21 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie 49 282 26 26 0
HSPA6-201 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 92 237 23 23 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 3 hippie, biogrid 82 252 28 28 0
HSPA9-201 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 47 284 19 19 2
HSPH1-201 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 3 hippie, biogrid 69 323 31 31 0
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
HYOU1-218 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 98 373 36 36 0
INF2-203 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 53 639 26 26 23
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KCNC4-206 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 0 0 0 0 0
KCNE3-201 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 intact 44 61 6 6 6
KHDC1-202 KHDC1 Q4VXA5 KH homology domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 33 23 2 2 0
KLHL26-201 KLHL26 Q53HC5 Kelch-like protein 26 chr19 Not Cancer Driver No 1 hippie, biogrid 61 56 4 4 0
KLHL34-201 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 hippie, biogrid 79 77 12 12 0
L3MBTL2-201 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 72 211 25 25 0
LCMT2-201 LCMT2 O60294 tRNA wybutosine-synthesizing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 79 33 2 2 0
LOXL4-201 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 74 123 5 5 0
LTV1-201 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 31 391 20 20 0
MANSC1-202 MANSC1 Q9H8J5 MANSC domain-containing protein 1 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 38 209 14 14 0
MAP3K3-202 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 48 356 27 27 0
MAS1-202 MAS1 P04201 Proto-oncogene Mas chr6 Not Cancer Driver No 1 hippie, biogrid 36 5 2 2 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 39 298 24 24 0
METTL3-201 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 60 274 24 24 0
MLF1-201 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 1 hippie, biogrid 29 244 27 27 0
MLF2-201 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 2 hippie, biogrid 32 189 27 27 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MRGPRX4-201 MRGPRX4 Q96LA9 Mas-related G-protein coupled receptor member X4 chr11 Not Cancer Driver No 1 hippie, biogrid 63 10 0 0 0
MS4A15-202 MS4A15 Q8N5U1 Membrane-spanning 4-domains subfamily A member 15 chr11 Not Cancer Driver No 1 hippie, biogrid 30 27 4 4 0
NBR1-206 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 88 562 41 41 0
NLRP8-201 NLRP8 Q86W28 NACHT, LRR and PYD domains-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 272 51 14 14 0
NPAS1-208 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 47 311 21 21 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
NRBP1-203 NRBP1 Q9UHY1 Nuclear receptor-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 44 190 19 19 0
NUDC-201 NUDC Q9Y266 Nuclear migration protein nudC chr1 Not Cancer Driver No 2 intact, hippie 29 237 23 23 0
OPRM1-202 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie 71 59 17 17 0
OR6T1-201 OR6T1 Q8NGN1 Olfactory receptor 6T1 chr11 Not Cancer Driver No 1 hippie, biogrid 102 0 0 0 0
P2RX6-202 P2RX6 O15547 P2X purinoceptor 6 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 22 43 1 1 0
PABPN1-201 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 Not Cancer Driver No 1 intact, hippie 24 241 15 15 0
PELI3-201 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 Not Cancer Driver No 1 hippie, biogrid 38 216 21 21 0
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 23 74 11 11 0
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 biogrid 71 98 5 5 0
PLD5-208 PLD5 Q8N7P1 Inactive phospholipase D5 chr1 Not Cancer Driver No 1 biogrid 124 62 14 14 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
POLR1D-201 POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 intact, hippie 15 88 12 12 7
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PSPC1-201 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 hippie, biogrid 73 368 61 61 0
PYCR3-207 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 Not Cancer Driver No 1 hippie 15 11 0 0 0
RAD21-201 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 84 421 56 56 3
RANBP3-202 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 Not Cancer Driver No 1 hippie 52 470 42 42 0
RCN2-203 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 27 125 7 7 0
RPS25-202 RPS25 P62851 Small ribosomal subunit protein eS25 chr11 Not Cancer Driver No 1 hippie, biogrid 12 60 7 7 0
RUVBL2-206 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 52 100 11 11 0
SHARPIN-202 SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 intact, hippie 29 237 13 13 0
SHMT2-201 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 45 58 4 4 1
SIM2-201 SIM2 Q14190 Single-minded homolog 2 chr21 Not Cancer Driver No 1 hippie, biogrid 48 262 9 9 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 80 113 15 15 5
ST13-201 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 hippie, biogrid 27 298 21 21 0
STIP1-201 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 2 hippie, biogrid 54 270 28 28 0
STYK1-201 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact, biogrid 67 35 7 7 0
SYNM-202 SYNM O15061 Synemin chr15 Not Cancer Driver No 4 hippie, biogrid 110 1259 91 91 0
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 intact, hippie 37 302 25 25 0
TAX1BP1-202 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 43 429 29 29 0
TBC1D22A-201 TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 Not Cancer Driver No 3 intact, hippie, biogrid 57 220 20 20 0
TBL1X-208 TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX Not Cancer Driver No 1 intact, hippie 63 181 23 23 0
TBL1Y-203 TBL1Y Q9BQ87 F-box-like/WD repeat-containing protein TBL1Y chrY Not Cancer Driver No 2 intact, hippie, biogrid 26 138 6 6 0
TBPL2-201 TBPL2 Q6SJ96 TATA box-binding protein-like 2 chr14 Not Cancer Driver No 1 hippie 32 161 19 19 0
TGS1-201 TGS1 Q96RS0 Trimethylguanosine synthase chr8 Not Cancer Driver No 1 hippie 76 488 41 41 0
TIGAR-201 TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 Not Cancer Driver No 1 hippie 33 39 8 8 0
TLE2-201 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 62 283 23 23 0
TMEM231-201 TMEM231 Q9H6L2 Transmembrane protein 231 chr16 Not Cancer Driver No 1 hippie, biogrid 11 16 0 0 2
TPT1-212 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 hippie 14 43 5 5 0
TPTE2-211 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 hippie, biogrid 131 34 9 9 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TSR1-201 TSR1 Q2NL82 Pre-rRNA-processing protein TSR1 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 46 334 23 23 0
TTLL1-201 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 Not Cancer Driver No 3 hippie, biogrid 45 49 8 8 0
TTLL12-201 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 Not Cancer Driver No 4 intact, hippie, biogrid 48 101 5 5 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 45 52 6 6 6
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 51 54 6 6 10
WDR41-201 WDR41 Q9HAD4 WD repeat-containing protein 41 chr5 Not Cancer Driver No 1 hippie, biogrid 34 23 2 2 0
WDR72-201 WDR72 Q3MJ13 WD repeat-containing protein 72 chr15 Not Cancer Driver No 1 hippie, biogrid 178 107 19 19 0
WIPI2-201 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 38 68 5 5 1
WRAP73-201 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 34 5 0 0 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie 19 81 7 7 0
ZBTB18-206 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 62 236 18 18 0
ZBTB38-201 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 95 649 49 49 0