Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTA2-201 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 42 | 39 | 3 | 3 | 15 |
| ACTB-217 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 96 | 43 | 5 | 5 | 4 |
| ACTBL2-201 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 60 | 29 | 3 | 3 | 0 |
| ACTC1-201 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 48 | 14 | 14 | 11 |
| ATN1-202 | ATN1 | P54259 | Atrophin-1 | chr12 | Not Cancer Driver | No | 1 | intact | 111 | 1176 | 109 | 109 | 5 |
| BACE2-202 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 23 | 1 | 1 | 0 |
| C5orf22-201 | C5orf22 | Q49AR2 | UPF0489 protein C5orf22 | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 89 | 7 | 7 | 0 |
| CASK-203 | CASK | O14936 | Peripheral plasma membrane protein CASK | chrX | Not Cancer Driver | No | 1 | intact, hippie | 80 | 285 | 27 | 27 | 4 |
| CDC45-201 | CDC45 | O75419 | Cell division control protein 45 homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 66 | 12 | 12 | 5 |
| CIAO1-203 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 20 | 2 | 2 | 0 |
| CMTM6-201 | CMTM6 | Q9NX76 | CKLF-like MARVEL transmembrane domain-containing protein 6 | chr3 | Not Cancer Driver | No | 1 | hippie | 8 | 30 | 1 | 1 | 0 |
| CNKSR1-202 | CNKSR1 | Q969H4 | Connector enhancer of kinase suppressor of ras 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 96 | 408 | 54 | 54 | 0 |
| CRYAA-201 | CRYAA | P02489 | Alpha-crystallin A chain | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 0 | 42 | 0 | 0 | 6 |
| CTNNA1-201 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | Census | Yes | 1 | hippie | 90 | 268 | 25 | 25 | 4 |
| DCAF7-205 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 0 | 0 | 0 | 0 |
| DICER1-201 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | Census, Compendium | Yes | 1 | hippie | 183 | 363 | 31 | 31 | 4 |
| DLG1-269 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 89 | 460 | 48 | 48 | 0 |
| DLG4-202 | DLG4 | P78352 | Disks large homolog 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 74 | 233 | 34 | 34 | 0 |
| DNAJC10-201 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | Not Cancer Driver | No | 1 | hippie | 77 | 37 | 3 | 3 | 0 |
| DYNC1H1-201 | DYNC1H1 | Q14204 | Cytoplasmic dynein 1 heavy chain 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 371 | 495 | 47 | 47 | 21 |
| ECI1-201 | ECI1 | P42126 | Enoyl-CoA delta isomerase 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 25 | 14 | 0 | 0 | 0 |
| EFHD1-201 | EFHD1 | Q9BUP0 | EF-hand domain-containing protein D1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 95 | 6 | 6 | 0 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 721 | 45 | 45 | 0 |
| ENST00000690765 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 0 | 0 | 0 | 0 |
| ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 376 | 324 | 95 | 95 | 2 |
| FAAP100-201 | FAAP100 | Q0VG06 | Fanconi anemia core complex-associated protein 100 | chr17 | Not Cancer Driver | No | 1 | hippie | 72 | 209 | 16 | 16 | 0 |
| FBN2-201 | FBN2 | P35556 | Fibrillin-2 | chr5 | Compendium | Yes | 1 | hippie | 476 | 137 | 21 | 21 | 27 |
| FBXO3-201 | FBXO3 | Q9UK99 | F-box only protein 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 51 | 2 | 2 | 0 |
| FGFR3-205 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | Census, Compendium | Yes | 1 | intact, hippie | 134 | 241 | 18 | 18 | 32 |
| FHL2-211 | FHL2 | Q14192 | Four and a half LIM domains protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 17 | 0 | 0 | 0 | 0 |
| FHL3-201 | FHL3 | Q13643 | Four and a half LIM domains protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| FN1-203 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | intact, hippie | 289 | 1249 | 137 | 137 | 8 |
| FNDC3B-202 | FNDC3B | Q53EP0 | Fibronectin type III domain-containing protein 3B | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 434 | 37 | 37 | 0 |
| GOPC-202 | GOPC | Q9HD26 | Golgi-associated PDZ and coiled-coil motif-containing protein | chr6 | Census | Yes | 1 | hippie | 40 | 263 | 27 | 27 | 0 |
| GRIN2C-201 | GRIN2C | Q14957 | Glutamate receptor ionotropic, NMDA 2C | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 78 | 278 | 3 | 3 | 0 |
| GSN-204 | GSN | P06396 | Gelsolin | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 318 | 18 | 18 | 1 |
| HOXA1-202 | HOXA1 | P49639 | Homeobox protein Hox-A1 | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 261 | 44 | 44 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 129 | 16 | 2 | 2 | 10 |
| HSPA4L-201 | HSPA4L | O95757 | Heat shock 70 kDa protein 4L | chr4 | Not Cancer Driver | No | 1 | hippie | 57 | 268 | 19 | 19 | 0 |
| HSPBP1-202 | HSPBP1 | Q9NZL4 | Hsp70-binding protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 130 | 6 | 6 | 0 |
| HTT-201 | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 261 | 668 | 51 | 51 | 2 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | Not Cancer Driver | No | 1 | hippie | 143 | 265 | 30 | 30 | 6 |
| KRTAP3-2-201 | KRTAP3-2 | Q9BYR7 | Keratin-associated protein 3-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 0 | 0 | 0 | 0 |
| LIN7C-201 | LIN7C | Q9NUP9 | Protein lin-7 homolog C | chr11 | Not Cancer Driver | No | 1 | hippie | 17 | 102 | 8 | 8 | 0 |
| LRP1-201 | LRP1 | Q07954 | Prolow-density lipoprotein receptor-related protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 512 | 319 | 38 | 38 | 1 |
| MAPK1-201 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | Census, Compendium | Yes | 1 | hippie | 52 | 2 | 0 | 0 | 6 |
| MAPK10-319 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | Not Cancer Driver | No | 1 | hippie | 72 | 107 | 15 | 15 | 0 |
| MAPK11-201 | MAPK11 | Q15759 | Mitogen-activated protein kinase 11 | chr22 | Not Cancer Driver | No | 1 | hippie | 22 | 64 | 2 | 2 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 0 | 0 | 0 |
| MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 32 | 49 | 3 | 3 | 0 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | Not Cancer Driver | No | 1 | hippie | 52 | 94 | 9 | 9 | 0 |
| MAPK9-207 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | Not Cancer Driver | No | 1 | hippie | 37 | 90 | 3 | 3 | 0 |
| MPDZ-202 | MPDZ | O75970 | Multiple PDZ domain protein | chr9 | Not Cancer Driver | No | 1 | hippie | 207 | 861 | 88 | 88 | 0 |
| MPP7-209 | MPP7 | Q5T2T1 | MAGUK p55 subfamily member 7 | chr10 | Not Cancer Driver | No | 1 | hippie | 105 | 199 | 60 | 60 | 0 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | Not Cancer Driver | No | 1 | hippie | 61 | 292 | 28 | 28 | 1 |
| NUP205-201 | NUP205 | Q92621 | Nuclear pore complex protein Nup205 | chr7 | Not Cancer Driver | No | 1 | hippie | 181 | 101 | 8 | 8 | 1 |
| OTUD4-201 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 94 | 789 | 74 | 74 | 0 |
| PNMA2-204 | PNMA2 | Q9UL42 | Paraneoplastic antigen Ma2 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 45 | 2 | 2 | 0 |
| PPP2CA-203 | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | Not Cancer Driver | No | 1 | hippie | 32 | 12 | 1 | 1 | 7 |
| PPP2R1A-201 | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 1 | hippie | 169 | 0 | 0 | 0 | 4 |
| PPP2R2A-202 | PPP2R2A | P63151 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 68 | 6 | 6 | 0 |
| PPP2R2D-201 | PPP2R2D | Q66LE6 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform | chr10 | Not Cancer Driver | No | 1 | hippie | 32 | 66 | 6 | 6 | 0 |
| PPP6R3-203 | PPP6R3 | Q5H9R7 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 77 | 389 | 37 | 37 | 0 |
| PRUNE1-201 | PRUNE1 | Q86TP1 | Exopolyphosphatase PRUNE1 | chr1 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 11 | 11 | 4 |
| PTK7-202 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | Not Cancer Driver | No | 1 | hippie | 113 | 359 | 43 | 43 | 0 |
| PTPN2-201 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 39 | 120 | 10 | 10 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 106 | 730 | 50 | 50 | 0 |
| ROR2-201 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | Not Cancer Driver | No | 1 | hippie | 164 | 304 | 58 | 58 | 5 |
| RPS11-201 | RPS11 | P62280 | Small ribosomal subunit protein uS17 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 6 | 0 | 0 | 0 |
| SAMHD1-221 | SAMHD1 | Q9Y3Z3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | chr20 | Not Cancer Driver | No | 1 | hippie | 80 | 91 | 9 | 9 | 12 |
| SNX2-201 | SNX2 | O60749 | Sorting nexin-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 218 | 9 | 9 | 0 |
| SORL1-201 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | Not Cancer Driver | No | 1 | hippie | 298 | 87 | 8 | 8 | 0 |
| SPRR3-201 | SPRR3 | Q9UBC9 | Small proline-rich protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 36 | 171 | 36 | 36 | 0 |
| TCOF1-207 | TCOF1 | Q13428 | Treacle protein | chr5 | Not Cancer Driver | No | 1 | hippie | 107 | 1462 | 109 | 109 | 1 |
| TXNDC9-201 | TXNDC9 | O14530 | Thioredoxin domain-containing protein 9 | chr2 | Not Cancer Driver | No | 1 | hippie | 11 | 40 | 2 | 2 | 0 |
| UBQLN1-202 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 545 | 38 | 38 | 0 |
| UTRN-204 | UTRN | P46939 | Utrophin | chr6 | Not Cancer Driver | No | 1 | hippie | 352 | 1287 | 137 | 137 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|