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EGLN1-201 ,EGLN1 ,Q9GZT9
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 22
  • Number of Interaction partner in hippie: 61
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AATK-201 AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact, biogrid 82 916 59 59 0
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 99 158 19 19 4
AKT2-206 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 57 84 9 9 2
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact, biogrid 233 577 79 79 12
APOBEC3C-201 APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 Not Cancer Driver No 1 hippie, biogrid 20 2 0 0 0
ARNT-202 ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 61 511 47 47 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie, biogrid 20 192 18 18 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 57 334 36 36 0
CBFA2T3-201 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 1 hippie 68 504 60 60 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CITED1-211 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX Not Cancer Driver No 1 hippie, biogrid 16 167 15 15 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 98 168 18 18 3
EEF1AKMT1-202 EEF1AKMT1 Q8WVE0 EEF1A lysine methyltransferase 1 chr13 Not Cancer Driver No 1 hippie 15 22 1 1 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 biogrid 346 223 30 30 1
EGLN1-201 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie 22 206 4 4 2
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EPAS1-201 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 3 intact, hippie 109 451 54 54 4
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 biogrid 249 315 32 32 1
ERP29-201 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact, hippie 24 34 4 4 0
EZR-202 EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 51 296 26 26 0
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, biogrid 134 241 18 18 32
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact, biogrid 101 163 27 27 0
FKBP4-201 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie 39 134 11 11 0
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 47 150 15 15 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 2 hippie, biogrid 50 161 19 19 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 biogrid 203 259 33 33 14
GPLD1-201 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 Not Cancer Driver No 1 hippie 117 37 7 7 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
HIF3A-205 HIF3A Q9Y2N7 Hypoxia-inducible factor 3-alpha chr19 Not Cancer Driver No 1 hippie 113 364 74 74 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 70 255 29 29 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 5 301 4 4 21
ING4-202 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 Not Cancer Driver No 1 hippie 22 108 12 12 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KEAP1-201 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 217 57 7 7 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie 771 7 2 2 22
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 76 95 12 12 1
LIMD1-201 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 47 430 29 29 0
MAGEA11-202 MAGEA11 P43364 Melanoma-associated antigen 11 chrX Not Cancer Driver No 1 hippie 94 218 39 39 0
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 1 intact, hippie 59 153 18 18 2
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact, biogrid 214 56 15 15 3
OS9-202 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 1 intact, hippie 62 451 43 43 0
OSR1-201 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 Not Cancer Driver No 1 hippie 40 67 11 11 0
PEX19-201 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 26 267 23 23 0
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 53 58 11 11 0
PLD1-201 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 hippie 126 133 21 21 1
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 71 98 5 5 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
POLR2A-210 POLR2A P24928 DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 138 847 36 36 2
POLR2C-201 POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 26 108 9 9 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 2 hippie, biogrid 8 52 2 2 0
RFPL4B-201 RFPL4B Q6ZWI9 Ret finger protein-like 4B chr6 Not Cancer Driver No 1 hippie, biogrid 53 0 0 0 0
RHOBTB3-201 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 Not Cancer Driver No 1 hippie 46 34 1 1 0
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RUNX3-201 RUNX3 Q13761 Runt-related transcription factor 3 chr1 Not Cancer Driver No 1 hippie 47 331 37 37 0
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 23 17 1 1 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 65 532 49 49 0
SIAH2-201 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 34 68 2 2 0
SNUPN-201 SNUPN O95149 Snurportin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 31 137 12 12 0
SPRY2-202 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie 32 170 19 19 1
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 68 42 4 4 12
TET2-203 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 150 1671 139 139 1
TET3-202 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 Not Cancer Driver No 1 hippie 160 1277 117 117 6
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 50 39 2 2 4
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 85 117 15 15 84
ZNF281-203 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 intact, hippie 62 710 44 44 0
ZNG1A-202 ZNG1A Q9BRT8 Zinc-regulated GTPase metalloprotein activator 1A chr9 Not Cancer Driver No 1 intact 20 59 4 4 0