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EIF3I-224 ,EIF3I ,Q13347
  • Number of Interaction partner in intact: 70
  • Number of Interaction partner in biogrid: 68
  • Number of Interaction partner in hippie: 212
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACO2-201 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie 77 172 16 16 5
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 96 43 5 5 4
ANGEL1-201 ANGEL1 Q9UNK9 Protein angel homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 67 161 20 20 0
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 37 154 11 11 0
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
ATG2A-201 ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact 175 891 104 104 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRD1-202 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 intact, hippie 117 424 47 47 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
C5orf58-206 C5orf58 C9J3I9 Putative uncharacterized protein C5orf58 chr5 Not Cancer Driver No 1 intact, hippie 7 14 0 0 0
CASP6-201 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 19 24 4 4 0
CCNA1-201 CCNA1 P78396 Cyclin-A1 chr13 Not Cancer Driver No 1 intact, hippie 77 65 18 18 0
CCND2-201 CCND2 P30279 G1/S-specific cyclin-D2 chr12 Census, Compendium Yes 1 hippie 29 30 5 5 3
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CD4-201 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 50 56 7 7 0
CD74-201 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 Census Yes 1 hippie 24 186 15 15 0
CD81-201 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 22 0 0 0 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDK11A-205 CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 Not Cancer Driver No 1 biogrid 50 488 32 32 0
CDK11B-204 CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 biogrid 66 502 29 29 0
CDK12-202 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 Census, Compendium Yes 1 biogrid 142 1203 92 92 0
CDK18-203 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 intact, hippie 47 132 12 12 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CERKL-201 CERKL Q49MI3 Ceramide kinase-like protein chr2 Not Cancer Driver No 2 intact, hippie, biogrid 98 90 28 28 1
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 216 145 9 9 130
CIC-206 CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 216 1552 207 207 0
CLEC4G-201 CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 intact, hippie 32 35 3 3 0
CPNE8-201 CPNE8 Q86YQ8 Copine-8 chr12 Not Cancer Driver No 1 hippie, biogrid 69 40 7 7 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 biogrid 47 75 6 6 4
CSNK2A2-201 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 2 hippie, biogrid 25 13 1 1 0
CSNK2A3-201 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 Not Cancer Driver No 1 biogrid 47 76 9 9 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
DCAF10-202 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 33 201 7 7 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 intact, hippie 91 302 32 32 18
DDX60-201 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 Not Cancer Driver No 1 intact, hippie 162 132 6 6 0
DHX15-201 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 intact, hippie 82 180 19 19 0
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 55 17 0 0 10
DNAJA4-202 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 31 111 5 5 0
DUX4-203 DUX4 Q9UBX2 Double homeobox protein 4 chr4 Not Cancer Driver No 1 hippie 0 407 0 0 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EIF1B-201 EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie, biogrid 10 6 0 0 0
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 hippie, biogrid 49 179 9 9 21
EIF3A-201 EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 Not Cancer Driver No 10 intact, hippie, biogrid 53 835 18 18 0
EIF3B-201 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 8 intact, hippie, biogrid 72 229 5 5 0
EIF3C-201 EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 8 intact, hippie, biogrid 3 392 1 1 0
EIF3CL-201 EIF3CL B5ME19 Eukaryotic translation initiation factor 3 subunit C-like protein chr16 Not Cancer Driver No 3 intact, hippie, biogrid 3 393 1 1 0
EIF3D-201 EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 6 intact, hippie, biogrid 51 200 20 20 0
EIF3E-201 EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 7 intact, hippie, biogrid 59 27 2 2 0
EIF3F-209 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 6 intact, hippie, biogrid 14 125 1 1 1
EIF3G-201 EIF3G O75821 Eukaryotic translation initiation factor 3 subunit G chr19 Not Cancer Driver No 8 intact, hippie, biogrid 31 235 20 20 0
EIF3H-209 EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 7 intact, hippie, biogrid 24 109 7 7 0
EIF3J-201 EIF3J O75822 Eukaryotic translation initiation factor 3 subunit J chr15 Not Cancer Driver No 4 intact, hippie, biogrid 7 166 4 4 0
EIF3K-201 EIF3K Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K chr19 Not Cancer Driver No 6 intact, hippie, biogrid 21 0 0 0 0
EIF3L-215 EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 6 intact, hippie, biogrid 45 41 1 1 0
EIF3M-208 EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 6 intact, hippie, biogrid 28 0 0 0 0
EIF4A1-201 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 2 intact, hippie, biogrid 32 35 4 4 0
EIF4A2-201 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 1 hippie, biogrid 64 27 11 11 0
EIF4B-201 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 80 588 76 76 0
EIF4E-203 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie, biogrid 18 54 4 4 0
EIF4EBP1-201 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 8 118 8 8 0
EIF4EBP2-201 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 13 119 12 12 0
EIF4ENIF1-201 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie, biogrid 86 902 75 75 0
EIF4G1-202 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 5 hippie, biogrid 157 1080 103 103 2
EIF4G3-201 EIF4G3 O43432 Eukaryotic translation initiation factor 4 gamma 3 chr1 Not Cancer Driver No 1 hippie, biogrid 157 1018 96 96 0
EIF5-201 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 49 185 15 15 0
EIF6-203 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 22 17 2 2 0
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPB41L1-202 EPB41L1 Q9H4G0 Band 4.1-like protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 125 579 93 93 1
ERCC6-201 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 142 837 82 82 9
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
ESRRA-201 ESRRA P11474 Steroid hormone receptor ERR1 chr11 Compendium Yes 1 hippie 27 101 9 9 0
ESRRG-209 ESRRG P62508 Estrogen-related receptor gamma chr1 Not Cancer Driver No 1 hippie 112 77 20 20 0
EXOSC6-201 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 Not Cancer Driver No 1 hippie 2 103 0 0 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 55 352 38 38 0
GAN-203 GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 48 33 3 3 20
GH1-201 GH1 P01241 Somatotropin chr17 Not Cancer Driver No 1 intact, hippie 41 24 7 7 14
GLI1-201 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 156 1018 138 138 0
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 2 intact, hippie, biogrid 517 971 113 113 1
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HLA-B-249 HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 49 169 18 18 0
HNF4G-201 HNF4G Q14541 Hepatocyte nuclear factor 4-gamma chr8 Not Cancer Driver No 1 hippie 99 96 26 26 0
HSD17B10-201 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 18 15 3 3 11
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 261 668 51 51 2
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
ICAM1-201 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 hippie 52 253 25 25 0
IFT172-201 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 Not Cancer Driver No 1 intact, hippie 154 96 4 4 8
IGSF8-201 IGSF8 Q969P0 Immunoglobulin superfamily member 8 chr1 Not Cancer Driver No 1 hippie 79 208 28 28 0
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 30 72 7 7 0
ITFG1-201 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 50 18 3 3 0
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 intact 44 61 6 6 6
KCTD12-201 KCTD12 Q96CX2 BTB/POZ domain-containing protein KCTD12 chr13 Not Cancer Driver No 1 hippie 12 149 5 5 0
KIF11-201 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 60 390 22 22 4
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KLF16-201 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 12 206 7 7 0
KLF8-204 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 intact, hippie 44 271 32 32 0
L1TD1-201 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 2 intact, hippie 91 543 72 72 0
LAMB1-201 LAMB1 P07942 Laminin subunit beta-1 chr7 Not Cancer Driver No 1 hippie 198 423 42 42 0
LAMC1-201 LAMC1 P11047 Laminin subunit gamma-1 chr1 Not Cancer Driver No 1 hippie 183 563 72 72 0
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 29 55 4 4 1
LIG4-202 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 103 63 10 10 2
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LYAR-201 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 34 250 19 19 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
METTL18-202 METTL18 O95568 Histidine protein methyltransferase 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 26 126 7 7 0
METTL3-201 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 60 274 24 24 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYL9-201 MYL9 P24844 Myosin regulatory light polypeptide 9 chr20 Not Cancer Driver No 1 hippie, biogrid 26 82 14 14 0
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 86 66 9 9 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NDUFB5-201 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 23 9 1 1 0
NES-201 NES P48681 Nestin chr1 Not Cancer Driver No 1 intact, hippie 203 1485 189 189 0
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 62 345 30 30 0
NFX1-203 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 89 492 28 28 0
NIPSNAP2-201 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 Not Cancer Driver No 1 hippie 24 6 1 1 0
NMRAL1-201 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 28 14 2 2 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
NR1H3-211 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 Not Cancer Driver No 1 hippie 44 147 13 13 0
NR1I2-202 NR1I2 O75469 Nuclear receptor subfamily 1 group I member 2 chr3 Not Cancer Driver No 1 hippie 45 82 9 9 0
NR1I3-204 NR1I3 Q14994 Nuclear receptor subfamily 1 group I member 3 chr1 Not Cancer Driver No 1 hippie 46 23 2 2 0
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NR3C2-203 NR3C2 P08235 Mineralocorticoid receptor chr4 Not Cancer Driver No 1 hippie 120 487 63 63 14
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDCD2-201 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 10 40 5 5 0
NUMA1-205 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 Census, Compendium Yes 1 hippie, biogrid 169 1869 147 147 0
ODF2-220 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 intact 99 609 72 72 0
OXSR1-201 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 1 hippie 51 208 22 22 0
PAK2-201 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 61 242 31 31 1
PAN2-221 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 104 78 8 8 0
PAXIP1-201 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 41 462 1 1 0
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PDC-201 PDC P20941 Phosducin chr1 Not Cancer Driver No 1 hippie 21 91 11 11 0
PDCD4-201 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 Not Cancer Driver No 1 hippie, biogrid 49 188 25 25 0
PDCL-201 PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 1 hippie 27 147 10 10 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 129 925 106 106 0
POLR1C-210 POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 28 1 1 12
PPARD-203 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie 51 70 5 5 0
PRRC2B-206 PRRC2B Q5JSZ5 Protein PRRC2B chr9 Not Cancer Driver No 3 intact, hippie, biogrid 211 2209 211 211 0
PSMC4-201 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 1 hippie 38 21 2 2 0
PYHIN1-203 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 139 293 81 81 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 20 67 9 9 0
RAD21-201 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 84 421 56 56 3
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact 64 169 30 30 18
RAN-212 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie, biogrid 18 14 0 0 0
RARB-214 RARB P10826 Retinoic acid receptor beta chr3 Not Cancer Driver No 1 hippie 60 148 17 17 3
RARG-203 RARG P13631 Retinoic acid receptor gamma chr12 Not Cancer Driver No 1 hippie 69 164 24 24 0
RBM39-201 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 53 228 16 16 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 64 420 31 31 0
RIOK2-201 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 52 255 26 26 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 Not Cancer Driver No 1 hippie 43 181 11 11 4
RORB-202 RORB Q92753 Nuclear receptor ROR-beta chr9 Not Cancer Driver No 1 hippie 75 87 15 15 1
RORC-201 RORC P51449 Nuclear receptor ROR-gamma chr1 Not Cancer Driver No 1 hippie 81 187 31 31 1
RPL10-202 RPL10 P27635 Large ribosomal subunit protein uL16 chrX Census, Compendium Yes 1 intact, hippie 41 9 2 2 4
RPL37A-210 RPL37A P61513 Large ribosomal subunit protein eL43 chr2 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
RPS13-202 RPS13 P62277 Small ribosomal subunit protein uS15 chr11 Not Cancer Driver No 1 hippie, biogrid 14 18 4 4 0
SETD2-202 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 Census, Compendium Yes 1 hippie, biogrid 233 1949 144 144 4
SFN-201 SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 16 75 3 3 0
SGK1-201 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 1 intact, hippie 43 86 13 13 0
SHANK3-201 SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains protein 3 chr22 Not Cancer Driver No 1 intact 98 1257 68 68 3
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SKA3-202 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 Not Cancer Driver No 1 hippie 35 232 22 22 0
SLC3A2-203 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 44 171 7 7 0
SNW1-201 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 59 487 53 53 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 14 94 9 9 57
SRRM1-201 SRRM1 Q8IYB3 Serine/arginine repetitive matrix protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 8 795 2 2 0
SRRM2-201 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 81 2749 81 81 0
SRSF6-201 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 29 259 12 12 0
SRSF7-201 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 hippie, biogrid 20 175 8 8 0
STX18-201 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 1 hippie, biogrid 23 176 12 12 0
SUB1-201 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie, biogrid 8 108 4 4 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 6 86 4 4 0
SUMO4-201 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 6 69 4 4 0
TADA2A-205 TADA2A O75478 Transcriptional adapter 2-alpha chr17 Not Cancer Driver No 1 hippie 39 70 4 4 0
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 36 202 12 12 21
TES-201 TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 28 100 6 6 0
TFE3-201 TFE3 P19532 Transcription factor E3 chrX Census Yes 1 intact, hippie 44 526 41 41 9
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 30 44 3 3 8
TGFBR2-201 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 hippie 93 61 15 15 21
THRB-216 THRB P10828 Thyroid hormone receptor beta chr3 Not Cancer Driver No 1 hippie 61 112 20 20 27
TMED2-201 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 16 25 2 2 0
TNFRSF14-201 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 intact, hippie 26 54 4 4 0
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TNNI1-202 TNNI1 P19237 Troponin I, slow skeletal muscle chr1 Not Cancer Driver No 1 hippie 26 72 4 4 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TPT1-212 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 14 43 5 5 0
TRA2B-204 TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 hippie, biogrid 24 244 20 20 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 51 62 5 5 0
TRIP12-201 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 154 847 82 82 4
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 25 32 4 4 0
UBR5-207 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie, biogrid 260 1299 135 135 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
USP3-202 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 48 45 3 3 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VDR-206 VDR P11473 Vitamin D3 receptor chr12 Not Cancer Driver No 1 hippie 36 102 7 7 14
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 67 316 45 45 1
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WIPI2-201 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 38 68 5 5 1
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
YBX1-201 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 31 312 31 31 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 intact 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact 21 78 4 4 3
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 intact 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 intact, hippie 19 81 7 7 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 36 929 33 33 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZKSCAN4-201 ZKSCAN4 Q969J2 Zinc finger protein with KRAB and SCAN domains 4 chr6 Not Cancer Driver No 1 intact 29 304 17 17 0
ZNF598-202 ZNF598 Q86UK7 E3 ubiquitin-protein ligase ZNF598 chr16 Not Cancer Driver No 1 hippie 68 567 47 47 0
ZNF746-201 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 68 437 43 43 0