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EIF4G3-201 ,EIF4G3 ,O43432
  • Number of Interaction partner in intact: 27
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 94
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALDH3A2-201 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 30 5 1 1 25
ANGEL1-201 ANGEL1 Q9UNK9 Protein angel homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 67 161 20 20 0
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 23 104 9 9 0
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 13 112 7 7 0
BCAT1-201 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie, biogrid 53 8 2 2 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
BTNL9-201 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 53 87 3 3 0
CAMK1-201 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 Not Cancer Driver No 1 hippie 32 31 1 1 0
CAMK2A-201 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 hippie, biogrid 62 62 10 10 7
CCT8L2-201 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 196 104 41 41 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
COMTD1-201 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 12 23 0 0 0
CRYBG2-201 CRYBG2 Q8N1P7 Beta/gamma crystallin domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie 43 1092 9 9 0
CTR9-201 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 intact, hippie 109 385 29 29 0
DAZL-202 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 23 129 11 11 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 106 520 65 65 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
EEA1-201 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 1 intact, hippie 104 1174 90 90 0
EFNB1-201 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie, biogrid 35 126 10 10 14
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 hippie, biogrid 49 179 9 9 21
EIF3A-201 EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 Not Cancer Driver No 1 hippie, biogrid 53 835 18 18 0
EIF3B-201 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 2 hippie, biogrid 72 229 5 5 0
EIF3C-201 EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 hippie, biogrid 3 392 1 1 0
EIF3D-201 EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 hippie, biogrid 51 200 20 20 0
EIF3E-201 EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie, biogrid 59 27 2 2 0
EIF3F-209 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 2 hippie, biogrid 14 125 1 1 1
EIF3G-201 EIF3G O75821 Eukaryotic translation initiation factor 3 subunit G chr19 Not Cancer Driver No 1 hippie, biogrid 31 235 20 20 0
EIF3H-209 EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 2 hippie, biogrid 24 109 7 7 0
EIF3I-224 EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 hippie, biogrid 38 46 5 5 0
EIF3K-201 EIF3K Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K chr19 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
EIF3L-215 EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 hippie, biogrid 45 41 1 1 0
EIF3M-208 EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
EIF4A1-201 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 5 intact, hippie, biogrid 32 35 4 4 0
EIF4A2-201 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 3 hippie, biogrid 64 27 11 11 0
EIF4E-203 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 6 hippie, biogrid 18 54 4 4 0
EIF4EBP1-201 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 8 118 8 8 0
EIF4EBP2-201 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 13 119 12 12 0
EIF4ENIF1-201 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie, biogrid 86 902 75 75 0
EIF4G1-202 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 2 hippie, biogrid 157 1080 103 103 2
EIF4G2-201 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 Not Cancer Driver No 1 hippie, biogrid 80 382 38 38 0
EPHA1-201 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 109 211 29 29 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
EZR-202 EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 51 296 26 26 0
GRWD1-201 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 32 188 9 9 0
HAO2-201 HAO2 Q9NYQ3 2-Hydroxyacid oxidase 2 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 63 12 3 3 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HSPA1L-201 HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 86 141 23 23 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 82 252 28 28 0
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 19
HTRA2-201 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 33 127 7 7 2
IFT140-203 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 Not Cancer Driver No 1 hippie 138 165 22 22 10
IMMP1L-209 IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 15 3 0 0 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
KPTN-201 KPTN Q9Y664 KICSTOR complex protein kaptin chr19 Not Cancer Driver No 3 hippie, biogrid 34 22 2 2 0
LGR4-201 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 73 16 2 2 0
LIG4-202 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 103 63 10 10 2
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
MKNK1-229 MKNK1 Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 chr1 Not Cancer Driver No 1 hippie 40 151 17 17 0
MRFAP1L1-201 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 8 59 4 4 0
MSI1-201 MSI1 O43347 RNA-binding protein Musashi homolog 1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 134 12 12 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NBEAL2-205 NBEAL2 Q6ZNJ1 Neurobeachin-like protein 2 chr3 Not Cancer Driver No 1 intact, hippie 222 515 47 47 8
NCBP1-202 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact, hippie 66 89 7 7 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NFATC2IP-201 NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 2 hippie, biogrid 33 331 23 23 0
NTAQ1-201 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 24 27 3 3 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 25 169 19 19 0
PABPC1-201 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 2 intact, hippie, biogrid 53 317 32 32 0
PABPC4-202 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 68 255 40 40 0
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 53 58 11 11 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PNKD-203 PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 2 intact, hippie, biogrid 31 160 13 13 2
PSMC3-201 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie, biogrid 38 131 8 8 0
PUS7-202 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 49 163 15 15 1
QPRT-202 QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 Not Cancer Driver No 3 intact, hippie, biogrid 23 7 1 1 0
RBFOX2-210 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 3 intact, hippie, biogrid 31 163 18 18 0
RPS27L-201 RPS27L Q71UM5 Ribosomal protein eS27-like chr15 Not Cancer Driver No 1 hippie, biogrid 3 22 1 1 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SF3A2-201 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 15 384 10 10 0
SHARPIN-202 SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 hippie, biogrid 29 237 13 13 0
SHC1-202 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 58 400 41 41 0
SIGLECL1-207 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 44 35 12 12 0
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 36 202 12 12 21
TENT5A-201 TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 1 intact, hippie 33 0 0 0 0
TGM1-201 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 1 hippie, biogrid 88 230 25 25 50
TGM7-201 TGM7 Q96PF1 Protein-glutamine gamma-glutamyltransferase Z chr15 Not Cancer Driver No 1 hippie, biogrid 99 80 8 8 0
THRSP-201 THRSP Q92748 Thyroid hormone-inducible hepatic protein chr11 Not Cancer Driver No 1 hippie, biogrid 20 47 5 5 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
USP10-201 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 65 423 34 34 0
VAV2-201 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 Not Cancer Driver No 1 intact, hippie 85 136 15 15 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
YTHDF2-201 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 48 376 29 29 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 1 intact 10 55 0 0 0