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ELK4-202 ,ELK4 ,P28324
  • Number of Interaction partner in intact: 69
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 65
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACADVL-203 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 30 101 2 2 34
ACAP2-201 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 Not Cancer Driver No 1 intact, hippie 66 287 26 26 0
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 96 43 5 5 4
ACTBL2-201 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie 60 29 3 3 0
ACTG1-205 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 intact, hippie 67 42 11 11 15
AKAP12-204 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 intact, hippie 156 1780 156 156 0
BCLAF1-214 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 Census, Compendium Yes 1 hippie 245 900 236 236 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CAPZA1-201 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 31 42 3 3 0
CAPZB-201 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 intact, hippie 17 66 1 1 0
CCL2-201 CCL2 P13500 C-C motif chemokine 2 chr17 Not Cancer Driver No 1 intact 19 15 5 5 0
CCL3-204 CCL3 P10147 C-C motif chemokine 3 chr17 Not Cancer Driver No 1 intact 13 0 0 0 0
CLNS1A-204 CLNS1A P54105 Methylosome subunit pICln chr11 Not Cancer Driver No 1 hippie 12 170 9 9 0
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 intact, hippie 41 84 12 12 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 54 102 2 2 0
DOK4-201 DOK4 Q8TEW6 Docking protein 4 chr16 Not Cancer Driver No 1 hippie 31 45 0 0 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ELK4-202 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 hippie 35 240 22 22 0
ENST00000621281 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 38 2 2 0
ERH-203 ERH P84090 Enhancer of rudimentary homolog chr14 Not Cancer Driver No 1 intact, hippie 5 11 0 0 0
FOS-201 FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 37 247 28 28 0
GRPEL1-201 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie 13 88 5 5 0
H2AC12-201 H2AC12 Q96KK5 Histone H2A type 1-H chr6 Not Cancer Driver No 1 intact 23 55 6 6 0
H2AC14-201 H2AC14 Q99878 Histone H2A type 1-J chr6 Not Cancer Driver No 1 intact 18 56 2 2 0
H2AC20-201 H2AC20 Q16777 Histone H2A type 2-C chr1 Not Cancer Driver No 1 intact 22 56 4 4 0
H2AC25-202 H2AC25 Q7L7L0 Histone H2A type 3 chr1 Not Cancer Driver No 1 intact 12 61 5 5 0
H2AC6-202 H2AC6 Q93077 Histone H2A type 1-C chr6 Not Cancer Driver No 1 intact 24 59 12 12 0
H2AC7-201 H2AC7 P20671 Histone H2A type 1-D chr6 Not Cancer Driver No 1 intact 19 63 9 9 0
H2AJ-203 H2AJ Q9BTM1 Histone H2A.J chr12 Not Cancer Driver No 1 intact 14 54 8 8 0
H2BC12-201 H2BC12 O60814 Histone H2B type 1-K chr6 Not Cancer Driver No 1 intact 20 78 9 9 0
H2BC12L-201 H2BC12L P57053 Histone H2B type F-S chr21 Not Cancer Driver No 1 intact 0 86 0 0 0
H2BC13-201 H2BC13 Q99880 Histone H2B type 1-L chr6 Not Cancer Driver No 1 intact 25 76 14 14 0
H2BC14-201 H2BC14 Q99879 Histone H2B type 1-M chr6 Not Cancer Driver No 1 intact 28 75 19 19 0
H2BC15-203 H2BC15 Q99877 Histone H2B type 1-N chr6 Not Cancer Driver No 1 intact 19 83 9 9 0
H2BC18-201 H2BC18 Q5QNW6 Histone H2B type 2-F chr1 Not Cancer Driver No 1 intact 20 77 11 11 0
H2BC9-201 H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 30 79 10 10 0
H3-4-201 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 25 53 7 7 0
H3-5-201 H3-5 Q6NXT2 Histone H3.3C chr12 Not Cancer Driver No 1 intact 27 50 7 7 0
H3C13-201 H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 28 51 12 12 0
H3C14-201 H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 0 51 0 0 0
H3C15-201 H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 0 51 0 0 0
H4C1-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 6 32 0 0 11
H4C11-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 18 31 2 2 11
H4C12-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 27 32 1 1 11
H4C13-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 17 31 4 4 11
H4C14-201 H4C16 P62805 Histone H4 chr1 Not Cancer Driver No 1 intact 0 31 0 0 11
H4C15-201 H4C16 P62805 Histone H4 chr1 Not Cancer Driver No 1 intact 0 31 0 0 11
H4C16-204 H4C16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 15 31 2 2 12
H4C2-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 32 3 3 11
H4C3-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 24 31 2 2 11
H4C4-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 1 1 11
H4C5-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 4 4 11
H4C6-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 18 31 1 1 11
H4C8-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 13 32 2 2 11
H4C9-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 4 4 11
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HNRNPUL1-204 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 59 535 22 22 0
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 19
ID1-202 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 Not Cancer Driver No 1 hippie 18 17 6 6 0
ID2-203 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 1 hippie 13 52 6 6 0
ID3-201 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 Census, Compendium Yes 1 hippie 10 34 3 3 0
IL18-201 IL18 Q14116 Interleukin-18 chr11 Not Cancer Driver No 1 intact 11 16 2 2 0
IL23A-201 IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 Not Cancer Driver No 1 intact 7 42 2 2 0
IL36A-201 IL36A Q9UHA7 Interleukin-36 alpha chr2 Not Cancer Driver No 1 intact 39 13 3 3 0
ITGA3-202 ITGA3 P26006 Integrin alpha-3 chr17 Not Cancer Driver No 1 intact, hippie 80 129 15 15 3
IVNS1ABP-202 IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 61 90 9 9 0
KIF11-201 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 60 390 22 22 4
LARP1-204 LARP1 Q6PKG0 La-related protein 1 chr5 Not Cancer Driver No 1 hippie 100 815 75 75 0
LIMA1-201 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 64 688 60 60 0
LUC7L3-208 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 intact, hippie 24 323 13 13 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPK11-201 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie 22 64 2 2 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MAPK7-204 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 hippie 56 490 31 31 0
MAPK8-206 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 52 94 9 9 0
MRPL16-201 MRPL16 Q9NX20 Large ribosomal subunit protein uL16m chr11 Not Cancer Driver No 1 intact, hippie 24 57 7 7 0
MRPL4-201 MRPL4 Q9BYD3 Large ribosomal subunit protein uL4m chr19 Not Cancer Driver No 1 intact, hippie 19 107 9 9 0
MTMR14-201 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 45 150 6 6 2
MYCBP-201 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 55 4 4 0
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 86 66 9 9 0
OTUD4-201 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 94 789 74 74 0
PABPC4-202 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 intact, hippie 68 255 40 40 0
PPBP-201 PPBP P02775 Platelet basic protein chr4 Not Cancer Driver No 1 intact 20 21 6 6 0
PPM1B-201 PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie 53 243 26 26 0
PRMT5-202 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 62 72 3 3 0
PRPF31-201 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 37 213 9 9 2
PRPS1-204 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie 28 0 0 0 16
PRPS2-202 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie 42 4 1 1 0
PRPSAP1-206 PRPSAP1 Q14558 Phosphoribosyl pyrophosphate synthase-associated protein 1 chr17 Not Cancer Driver No 1 hippie 36 50 4 4 0
PRPSAP2-201 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 Not Cancer Driver No 1 hippie 39 20 3 3 0
RIOK1-202 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 intact, hippie 52 303 30 30 0
ROCK1-201 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 Not Cancer Driver No 1 hippie 116 780 61 61 0
SERPINH1-201 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 intact, hippie 45 53 5 5 1
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SNRPD1-201 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 intact, hippie 4 80 0 0 0
SNRPD2-201 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 intact, hippie 16 67 8 8 0
SRF-201 SRF P11831 Serum response factor chr6 Not Cancer Driver No 2 intact, hippie 30 443 29 29 0
SRSF7-201 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 intact, hippie 20 175 8 8 0
TCF25-201 TCF25 Q9BQ70 Ribosome quality control complex subunit TCF25 chr16 Not Cancer Driver No 1 hippie 59 281 29 29 0
THRAP3-201 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie 78 957 81 81 0
TNFSF4-201 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 Not Cancer Driver No 1 intact 17 1 0 0 0
TRA2B-204 TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 intact, hippie 24 244 20 20 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 intact, hippie 25 42 2 2 0
YBX3-201 YBX3 P16989 Y-box-binding protein 3 chr12 Not Cancer Driver No 1 intact, hippie 34 362 33 33 0