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EMC1-207 ,EMC1 ,Q8N766
  • Number of Interaction partner in intact: 46
  • Number of Interaction partner in biogrid: 105
  • Number of Interaction partner in hippie: 374
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie 54 28 2 2 12
ACADVL-203 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 hippie 30 101 2 2 34
ACLY-201 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 88 114 9 9 0
ACSL3-201 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 Census, Compendium Yes 1 hippie 55 47 3 3 0
ADPGK-202 ADPGK Q9BRR6 ADP-dependent glucokinase chr15 Not Cancer Driver No 1 hippie, biogrid 33 24 0 0 0
AFG3L2-201 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie 38 162 5 5 17
AGL-203 AGL P35573 Glycogen debranching enzyme chr1 Not Cancer Driver No 1 hippie 139 144 17 17 1
AHNAK-202 AHNAK Q09666 Neuroblast differentiation-associated protein AHNAK chr11 Not Cancer Driver No 1 hippie 608 5807 602 602 0
AHNAK2-201 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie 765 5691 757 757 0
AIMP1-211 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 hippie 24 164 13 13 0
AK2-214 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie 17 76 8 8 2
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
ALDH7A1-201 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 Not Cancer Driver No 1 hippie 41 26 0 0 8
ALDOA-206 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie 36 65 7 7 3
ANP32B-201 ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 8 117 1 1 0
ANPEP-201 ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 126 110 21 21 0
ANXA1-201 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 36 61 7 7 0
ANXA2-204 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 38 21 2 2 0
ANXA3-201 ANXA3 P12429 Annexin A3 chr4 Not Cancer Driver No 1 hippie 41 22 3 3 0
ANXA5-201 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 hippie 37 33 4 4 0
APOA2-201 APOA2 P02652 Apolipoprotein A-II chr1 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
APOC3-201 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 hippie, biogrid 10 13 2 2 1
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ARMCX3-203 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 29 77 7 7 0
ASS1-201 ASS1 P00966 Argininosuccinate synthase chr9 Not Cancer Driver No 1 hippie 50 63 8 8 66
ATAD1-204 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 Not Cancer Driver No 1 hippie 23 71 3 3 0
ATG2A-201 ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 175 891 104 104 0
ATP13A1-202 ATP13A1 Q9HD20 Endoplasmic reticulum transmembrane helix translocase chr19 Not Cancer Driver No 1 hippie 100 95 13 13 0
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie 76 115 14 14 6
ATP1B3-201 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 Not Cancer Driver No 3 hippie, biogrid 19 6 0 0 0
ATP1B4-201 ATP1B4 Q9UN42 Protein ATP1B4 chrX Not Cancer Driver No 3 intact, hippie, biogrid 67 80 15 15 0
ATP2A2-204 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie 106 78 13 13 40
ATP2B1-202 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie 103 294 30 30 9
ATP2B4-203 ATP2B4 P23634 Plasma membrane calcium-transporting ATPase 4 chr1 Not Cancer Driver No 1 hippie 113 264 20 20 0
ATP2C1-218 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 Not Cancer Driver No 1 hippie 84 44 6 6 19
ATP5F1A-202 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 48 23 3 3 2
ATP5F1B-201 ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 85 7 7 1
ATP6AP1-201 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 2 hippie, biogrid 52 0 0 0 4
ATP6AP2-217 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie 36 0 0 0 2
ATP6V0A1-202 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 1 hippie 73 86 12 12 3
ATP6V0A2-201 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 1 hippie 65 36 5 5 0
ATP6V0D1-201 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie 28 0 0 0 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 biogrid 25 180 17 17 0
BASP1-201 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie 12 227 12 12 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 27 104 13 13 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 16 16 0
BTNL3-201 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 71 50 10 10 0
BZW2-201 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 Not Cancer Driver No 1 hippie 31 59 6 6 0
CA9-201 CA9 Q16790 Carbonic anhydrase 9 chr9 Not Cancer Driver No 1 hippie 56 276 40 40 0
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie 28 245 16 16 0
CALR3-201 CALR3 Q96L12 Calreticulin-3 chr19 Not Cancer Driver No 2 hippie, biogrid 42 103 15 15 0
CALU-201 CALU O43852 Calumenin chr7 Not Cancer Driver No 2 hippie, biogrid 15 130 9 9 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 2 intact, hippie 57 334 36 36 0
CAPNS1-201 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 21 59 5 5 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 23 2 0 0 0
CCT7-201 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 45 36 3 3 0
CD109-201 CD109 Q6YHK3 CD109 antigen chr6 Not Cancer Driver No 1 hippie 151 54 9 9 0
CD274-202 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 26 54 9 9 0
CD55-204 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie 30 128 11 11 1
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CENPH-201 CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie 20 85 6 6 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHCHD2-201 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 10 114 7 7 1
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie 44 412 36 36 0
CLEC4D-201 CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 52 18 3 3 0
CLEC4E-201 CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 42 5 2 2 0
COASY-201 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie 43 50 4 4 1
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 13 5 1 1 1
COX5B-201 COX5B P10606 Cytochrome c oxidase subunit 5B, mitochondrial chr2 Not Cancer Driver No 1 hippie 13 58 6 6 0
CPS1-201 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie 300 73 18 18 123
CPSF3-201 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 Not Cancer Driver No 1 hippie 55 56 8 8 1
CPT1A-201 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 Not Cancer Driver No 1 hippie 115 65 10 10 15
CSE1L-201 CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie 77 32 4 4 0
CTDNEP1-210 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 intact, hippie 12 0 0 0 0
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
CTSS-201 CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie 40 99 15 15 0
CYB5B-201 CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie 16 59 2 2 0
CYB5R1-201 CYB5R1 Q9UHQ9 NADH-cytochrome b5 reductase 1 chr1 Not Cancer Driver No 1 hippie 38 22 0 0 0
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie 28 24 2 2 8
CYC1-201 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie 44 35 2 2 2
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 20 13 3 3 1
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 intact, hippie 17 12 0 0 0
DERL2-201 DERL2 Q9GZP9 Derlin-2 chr17 Not Cancer Driver No 1 intact, hippie 13 15 0 0 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 106 520 65 65 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie 34 174 18 18 0
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 41 141 19 19 2
DNAJB12-203 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 28 227 11 11 0
DNAJB9-201 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 21 109 12 12 0
DNAJC1-202 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 50 315 38 38 0
DNAJC10-201 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie, biogrid 77 37 3 3 0
DNAJC14-205 DNAJC14 Q6Y2X3 DnaJ homolog subfamily C member 14 chr12 Not Cancer Driver No 1 hippie, biogrid 74 372 44 44 0
DNAJC16-202 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie, biogrid 51 64 2 2 0
DNAJC22-202 DNAJC22 Q8N4W6 DnaJ homolog subfamily C member 22 chr12 Not Cancer Driver No 1 hippie, biogrid 35 11 1 1 0
DNAJC25-201 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 23 39 3 3 0
DNAJC3-202 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 40 131 13 13 0
DNAJC30-201 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 13 83 3 3 3
DPP4-201 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 108 8 0 0 0
DYNC1H1-201 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie 371 495 47 47 21
ECHS1-201 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie 31 7 1 1 14
EDEM3-201 EDEM3 Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 chr1 Not Cancer Driver No 1 hippie 76 304 29 29 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 2 hippie, biogrid 77 61 4 4 2
EMC10-201 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 18 111 13 13 0
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 6 intact, hippie, biogrid 38 29 2 2 0
EMC3-201 EMC3 Q9P0I2 ER membrane protein complex subunit 3 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 17 31 2 2 0
EMC4-202 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 8 17 1 1 0
EMC6-201 EMC6 Q9BV81 ER membrane protein complex subunit 6 chr17 Not Cancer Driver No 1 hippie, biogrid 3 0 0 0 0
EMC7-201 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 22 54 4 4 0
EMC8-201 EMC8 O43402 ER membrane protein complex subunit 8 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 13 21 0 0 0
EMC9-201 EMC9 Q9Y3B6 ER membrane protein complex subunit 9 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 18 17 1 1 0
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 intact, hippie 37 21 2 2 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPHA10-202 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 1 intact, biogrid 129 226 36 36 0
EPHA7-202 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 2 intact, hippie, biogrid 226 71 10 10 0
EPHA8-201 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 intact, biogrid 156 122 16 16 0
ERLIN1-203 ERLIN1 O75477 Erlin-1 chr10 Not Cancer Driver No 1 hippie 19 46 3 3 1
ERLIN2-204 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie 29 22 2 2 0
ERMP1-202 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 Not Cancer Driver No 1 hippie 54 95 4 4 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
ETFA-203 ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie 18 34 0 0 3
EXTL2-202 EXTL2 Q9UBQ6 Exostosin-like 2 chr1 Not Cancer Driver No 1 hippie 29 0 0 0 0
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 36 171 11 11 0
FAM162A-203 FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 hippie 10 53 4 4 0
FASN-201 FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 241 310 33 33 0
FBXO2-201 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 76 0 0 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FDPS-202 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 biogrid 50 0 0 0 1
FIS1-201 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 9 6 0 0 0
FKBP10-201 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie 48 134 6 6 3
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 50 161 19 19 0
FLOT1-201 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 122 10 10 0
FOLR1-202 FOLR1 P15328 Folate receptor alpha chr11 Not Cancer Driver No 1 hippie 24 13 1 1 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 1 hippie 63 312 40 40 0
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 64 71 11 11 0
GALNT2-201 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie 70 122 18 18 2
GANAB-202 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 91 133 17 17 3
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 36 24 3 3 0
GCN1-201 GCN1 Q92616 Stalled ribosome sensor GCN1 chr12 Not Cancer Driver No 1 hippie 255 117 13 13 0
GDI2-203 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie 34 23 1 1 0
GFPT1-201 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 Not Cancer Driver No 1 hippie 59 75 5 5 12
GNAI1-228 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 1 hippie 39 11 2 2 9
GNAI3-201 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 36 12 0 0 1
GOSR2-232 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 1 hippie 16 106 10 10 2
GPI-201 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie 56 73 10 10 23
GTF2H4-201 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 Not Cancer Driver No 1 biogrid 33 30 4 4 0
GYS1-202 GYS1 P13807 Glycogen [starch] synthase, muscle chr19 Not Cancer Driver No 1 hippie 74 127 10 10 0
HDGF-201 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 25 203 21 21 0
HK1-202 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 90 76 13 13 6
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie 38 125 16 16 0
HLA-C-201 HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie 36 175 14 14 0
HM13-201 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 Not Cancer Driver No 1 hippie 30 61 3 3 0
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 23 25 3 3 0
HSPA13-201 HSPA13 P48723 Heat shock 70 kDa protein 13 chr21 Not Cancer Driver No 1 hippie, biogrid 58 48 6 6 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 50 352 21 21 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 49 282 26 26 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
ICAM1-201 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 hippie 52 253 25 25 0
ILF2-201 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 24 92 2 2 0
ILF3-218 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 57 676 39 39 0
IMPDH2-201 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie 52 6 1 1 0
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact, biogrid 139 282 37 37 63
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITGB1-201 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 73 84 8 8 0
KIDINS220-201 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie 166 684 78 78 0
KLHL22-201 KLHL22 Q53GT1 Kelch-like protein 22 chr22 Not Cancer Driver No 1 hippie, biogrid 75 50 7 7 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 771 7 2 2 22
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 88 408 46 46 0
L1CAM-205 L1CAM P32004 Neural cell adhesion molecule L1 chrX Not Cancer Driver No 1 hippie 181 443 65 65 65
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 36 94 8 8 0
LDHA-205 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 25 9 0 0 0
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie 50 223 18 18 1
LMAN2-201 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie 37 36 6 6 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 intact, hippie 50 547 34 34 117
LONP1-201 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie 75 178 16 16 10
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 78 85 10 10 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 4 17 0 0 0
MBOAT7-201 MBOAT7 Q96N66 Lysophospholipid acyltransferase 7 chr19 Not Cancer Driver No 1 hippie 48 25 1 1 0
MBTPS2-202 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 41 16 3 3 9
MDH1-201 MDH1 P40925 Malate dehydrogenase, cytoplasmic chr2 Not Cancer Driver No 1 hippie 32 18 1 1 1
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie 26 8 1 1 3
MED1-201 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 1 biogrid 81 1104 50 50 0
MED23-205 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 biogrid 109 28 3 3 1
MELTF-201 MELTF P08582 Melanotransferrin chr3 Not Cancer Driver No 1 hippie 75 23 5 5 0
MGST1-205 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie 18 0 0 0 0
MME-201 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 156 40 17 17 4
MMGT1-201 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 3 intact, hippie, biogrid 15 17 4 4 0
MMP15-201 MMP15 P51511 Matrix metalloproteinase-15 chr16 Not Cancer Driver No 1 hippie 63 206 19 19 0
MRPL23-205 MRPL23 Q16540 Large ribosomal subunit protein uL23m chr11 Not Cancer Driver No 1 hippie 20 68 9 9 0
MRPL37-202 MRPL37 Q9BZE1 Large ribosomal subunit protein mL37 chr1 Not Cancer Driver No 1 hippie 33 36 3 3 0
MRPL48-201 MRPL48 Q96GC5 Large ribosomal subunit protein mL48 chr11 Not Cancer Driver No 1 hippie 10 15 0 0 0
MSLN-201 MSLN Q13421 Mesothelin chr16 Not Cancer Driver No 1 hippie 57 129 15 15 0
MYOF-202 MYOF Q9NZM1 Myoferlin chr10 Not Cancer Driver No 1 hippie 180 403 35 35 0
NASP-201 NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 hippie 61 618 53 53 0
NDFIP1-201 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 17 45 3 3 0
NDUFA9-201 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie 37 8 0 0 2
NDUFB5-201 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie 23 9 1 1 0
NDUFB9-201 NDUFB9 Q9Y6M9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 chr8 Not Cancer Driver No 1 hippie 20 34 4 4 1
NDUFS1-201 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie 58 40 3 3 2
NDUFS2-224 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie 44 51 4 4 4
NDUFV1-201 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie 45 57 3 3 3
NNT-202 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie 96 47 5 5 11
NOMO1-201 NOMO1 Q15155 BOS complex subunit NOMO1 chr16 Not Cancer Driver No 1 hippie, biogrid 98 128 12 12 0
NOP56-201 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie, biogrid 56 194 26 26 0
NPC1-201 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 113 25 0 0 135
NPEPPS-201 NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 Compendium Yes 1 hippie 69 45 2 2 0
NSDHL-201 NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX Not Cancer Driver No 1 hippie 46 39 5 5 3
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUP210-201 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie 213 157 14 14 0
OGDH-201 OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie 120 106 18 18 0
OGDHL-201 OGDHL Q9ULD0 2-oxoglutarate dehydrogenase-like, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 221 129 34 34 0
OMA1-201 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 hippie 39 35 3 3 0
OR4N2-203 OR4N2 Q8NGD1 Olfactory receptor 4N2 chr14 Not Cancer Driver No 1 hippie, biogrid 179 0 0 0 0
OTULINL-201 OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 34 21 0 0 0
OXA1L-212 OXA1L Q15070 Mitochondrial inner membrane protein OXA1L chr14 Not Cancer Driver No 1 hippie 28 81 5 5 0
P2RX4-202 P2RX4 Q99571 P2X purinoceptor 4 chr12 Not Cancer Driver No 2 hippie, biogrid 20 0 0 0 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 41 80 13 13 1
PAICS-207 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie 16 35 1 1 0
PCK2-201 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 Not Cancer Driver No 1 hippie 65 139 9 9 0
PDE2A-201 PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 Not Cancer Driver No 1 hippie 82 99 5 5 0
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PGAM1-201 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie 12 70 4 4 0
PGM1-202 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie 38 31 2 2 12
PIGK-202 PIGK Q92643 GPI-anchor transamidase chr1 Not Cancer Driver No 1 hippie 43 37 7 7 5
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 53 58 11 11 0
PLD3-207 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 51 62 6 6 0
PLD4-201 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 Not Cancer Driver No 1 biogrid 34 75 7 7 0
PLD6-201 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 1 biogrid 20 24 3 3 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLGRKT-201 PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 11 0 0 0 0
PLOD1-201 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie 61 12 0 0 5
PLOD2-202 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 Not Cancer Driver No 1 hippie 84 17 2 2 3
PON2-201 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 25 13 0 0 0
POR-218 POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie 49 94 4 4 9
POTEF-202 POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 1 hippie, biogrid 174 456 63 63 0
PPP1R12A-203 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 hippie 76 822 63 63 0
PRDX3-201 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie 17 23 2 2 2
PRDX6-201 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie 32 13 3 3 0
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 385 421 43 43 2
PRPF6-201 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie 99 380 45 45 1
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 intact, hippie 43 134 18 18 69
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 35 64 5 5 0
PSMD1-201 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 77 201 14 14 0
PTGES2-202 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie 25 30 1 1 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 36 141 17 17 0
PTPRO-201 PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 155 137 28 28 0
PTRH2-201 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 7 19 1 1 1
PYGB-201 PYGB P11216 Glycogen phosphorylase, brain form chr20 Not Cancer Driver No 1 hippie 78 29 5 5 0
PYGL-201 PYGL P06737 Glycogen phosphorylase, liver form chr14 Not Cancer Driver No 1 hippie 82 23 1 1 2
RAB14-201 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie 10 41 3 3 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 15 58 3 3 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie 20 67 9 9 0
RAB7A-201 RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 2 hippie, biogrid 19 11 0 0 4
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RALA-201 RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 29 34 3 3 4
RALB-201 RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 1 hippie 29 35 4 4 0
RANBP1-201 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 hippie 13 137 11 11 0
RANBP2-201 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 1 hippie 295 1392 125 125 3
RANGAP1-201 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 1 hippie 40 160 12 12 0
RB1CC1-201 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 150 579 56 56 0
RER1-209 RER1 O15258 Protein RER1 chr1 Not Cancer Driver No 1 hippie 12 15 1 1 0
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 intact, biogrid 176 108 11 11 91
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 16 10 0 0 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 32 12 3 3 0
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RHOT2-201 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 40 81 4 4 0
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RND1-201 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 35 9 1 1 0
RND2-202 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 17 54 4 4 0
RND3-201 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 23 70 7 7 0
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 Not Cancer Driver No 1 biogrid 32 43 2 2 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 biogrid 164 304 58 58 5
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 48 26 3 3 0
RSL1D1-204 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 34 276 18 18 0
RTN4-202 RTN4 Q9NQC3 Reticulon-4 chr2 Not Cancer Driver No 1 hippie 81 868 50 50 0
S100A11-201 S100A11 P31949 Protein S100-A11 chr1 Not Cancer Driver No 1 hippie 9 14 2 2 0
SCARB2-201 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 46 13 3 3 1
SCFD1-203 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 46 117 9 9 0
SCGB1C1-201 SCGB1C1 Q8TD33 Secretoglobin family 1C member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
SCGB1D1-201 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
SDHA-201 SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 hippie 87 72 9 9 7
SDHB-201 SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 hippie 30 17 1 1 21
SEC11A-201 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 Not Cancer Driver No 1 hippie 15 0 0 0 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SEC63-201 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 67 267 25 25 0
SF3A1-201 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 65 632 53 53 0
SF3B1-201 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie 205 479 54 54 0
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie 21 29 0 0 0
SFXN3-201 SFXN3 Q9BWM7 Sideroflexin-3 chr10 Not Cancer Driver No 1 hippie 29 0 0 0 0
SLC12A3-203 SLC12A3 P55017 Solute carrier family 12 member 3 chr16 Not Cancer Driver No 1 hippie 109 125 14 14 99
SLC25A11-201 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 hippie 31 16 1 1 3
SLC25A12-202 SLC25A12 O75746 Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial chr2 Not Cancer Driver No 1 hippie 77 21 4 4 2
SLC25A13-201 SLC25A13 Q9UJS0 Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial chr7 Not Cancer Driver No 1 hippie 73 23 2 2 1
SLC25A24-203 SLC25A24 Q6NUK1 Mitochondrial adenyl nucleotide antiporter SLC25A24 chr1 Not Cancer Driver No 1 hippie 28 21 1 1 1
SLC25A4-201 SLC25A4 P12235 ADP/ATP translocase 1 chr4 Not Cancer Driver No 1 hippie 18 0 0 0 9
SLC25A46-201 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 28 98 2 2 4
SLC25A5-201 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 hippie 26 0 0 0 0
SLC25A6-201 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie 29 0 0 0 0
SLC4A7-201 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie 105 405 37 37 0
SMC3-201 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie 116 605 49 49 0
SNAP23-201 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie 12 180 10 10 0
SNIP1-201 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 biogrid 45 286 32 32 1
SOAT1-201 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 hippie 55 51 1 1 0
SPCS1-201 SPCS1 Q9Y6A9 Signal peptidase complex subunit 1 chr3 Not Cancer Driver No 1 hippie 9 82 4 4 0
SPCS2-201 SPCS2 Q15005 Signal peptidase complex subunit 2 chr11 Not Cancer Driver No 1 hippie 11 0 0 0 0
SPPL3-201 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 Not Cancer Driver No 1 hippie, biogrid 39 23 0 0 0
ST14-201 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 hippie, biogrid 86 47 5 5 1
ST7-201 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 37 64 6 6 0
STOM-201 STOM P27105 Stomatin chr9 Not Cancer Driver No 1 hippie 18 44 2 2 0
STOML2-201 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 Not Cancer Driver No 1 hippie 27 117 6 6 0
STT3A-201 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie 60 27 1 1 4
STT3B-201 STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 hippie 48 136 8 8 0
SUB1-201 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie 8 108 4 4 0
SUPT5H-204 SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 115 574 58 58 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TAGLN2-203 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie 18 83 8 8 0
TCIRG1-201 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 Compendium Yes 1 hippie 53 103 4 4 5
TCTN1-225 TCTN1 Q2MV58 Tectonic-1 chr12 Not Cancer Driver No 1 intact, hippie 56 47 6 6 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 62 23 2 2 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 40 169 12 12 0
TFRC-201 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 66 80 4 4 1
TIMM44-201 TIMM44 O43615 Mitochondrial import inner membrane translocase subunit TIM44 chr19 Not Cancer Driver No 1 hippie 38 175 17 17 0
TKT-207 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie 44 86 5 5 1
TLN1-201 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie 211 1110 90 90 0
TMBIM4-202 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 Not Cancer Driver No 1 hippie 25 3 0 0 0
TMED10-201 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 19 15 2 2 0
TMED2-201 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 16 25 2 2 0
TMED4-203 TMED4 Q7Z7H5 Transmembrane emp24 domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie 14 34 1 1 0
TMED5-202 TMED5 Q9Y3A6 Transmembrane emp24 domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 14 1 0 0 0
TMED9-201 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 12 22 2 2 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMEM120B-204 TMEM120B A0PK00 Transmembrane protein 120B chr12 Not Cancer Driver No 1 hippie, biogrid 24 6 1 1 0
TMEM17-201 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 15 14 1 1 0
TMEM216-203 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 7 0 0 0 5
TMEM237-203 TMEM237 Q96Q45 Transmembrane protein 237 chr2 Not Cancer Driver No 1 intact, hippie 28 178 14 14 0
TMEM43-201 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 hippie 42 57 8 8 3
TMEM67-205 TMEM67 Q5HYA8 Meckelin chr8 Not Cancer Driver No 1 intact, hippie 85 11 0 0 45
TMPRSS11B-201 TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 77 5 0 0 0
TMPRSS13-202 TMPRSS13 Q9BYE2 Transmembrane protease serine 13 chr11 Not Cancer Driver No 1 hippie, biogrid 56 205 28 28 0
TMPRSS2-201 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 47 25 3 3 0
TMTC3-201 TMTC3 Q6ZXV5 Protein O-mannosyl-transferase TMTC3 chr12 Not Cancer Driver No 1 hippie 90 82 4 4 2
TNIK-204 TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 126 782 86 86 0
TOMM70-201 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 Not Cancer Driver No 1 hippie 47 141 7 7 0
TOR1AIP1-212 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 53 400 33 33 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TPI1-202 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie 27 15 0 0 7
TPR-201 TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 215 1994 184 184 0
TPTE-204 TPTE P56180 Putative tyrosine-protein phosphatase TPTE chr21 Not Cancer Driver No 1 intact, hippie 422 48 41 41 0
TRDN-201 TRDN Q13061 Triadin chr6 Not Cancer Driver No 1 hippie, biogrid 59 646 55 55 1
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TSC22D1-203 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 83 1028 74 74 0
UBAC2-203 UBAC2 Q8NBM4 Ubiquitin-associated domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie 27 57 9 9 0
UGGT1-201 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 hippie 113 162 14 14 0
UNC93B1-201 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 42 127 3 3 0
UQCRC1-201 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie 41 55 3 3 2
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie 31 48 5 5 1
UQCRFS1-201 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie 27 47 1 1 1
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie, biogrid 20 184 11 11 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie 25 36 4 4 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 intact, hippie 22 9 1 1 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 55 99 7 7 1
VSTM1-201 VSTM1 Q6UX27 V-set and transmembrane domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 54 126 31 31 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
XPO5-201 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 85 64 6 6 0
YME1L1-201 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 hippie 80 136 10 10 1
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 intact 19 110 3 3 0
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 1 intact 10 55 0 0 0
ZACN-201 ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 Not Cancer Driver No 3 hippie, biogrid 33 48 3 3 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie 46 23 0 0 3