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EPRS1-201 ,EPRS1 ,P07814
  • Number of Interaction partner in intact: 62
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 0
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 intact 94 87 10 10 1
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact 91 142 12 12 10
AIMP1-211 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 intact 24 164 13 13 0
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact 13 112 7 7 0
CACNA1C-220 CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 Not Cancer Driver No 1 intact 350 708 123 123 25
CDK5-204 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 intact 38 5 0 0 0
CEP63-216 CEP63 Q96MT8 Centrosomal protein of 63 kDa chr3 Not Cancer Driver No 1 intact 77 508 50 50 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact 216 145 9 9 130
COQ2-206 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact 16 25 0 0 17
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact 127 65 9 9 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact 98 168 18 18 3
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact 55 17 0 0 10
DLST-202 DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact 33 192 23 23 1
DTX4-201 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 Not Cancer Driver No 1 intact 59 326 39 39 0
EEF1D-246 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 intact 30 153 20 20 0
EPRS1-201 EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 151 373 38 38 1
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact 69 92 10 10 1
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact 134 241 18 18 32
H2BC21-201 H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 30 77 13 13 0
H3-4-201 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 25 53 7 7 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 2 intact 23 25 3 3 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact 44 258 15 15 0
HUNK-201 HUNK P57058 Hormonally up-regulated neu tumor-associated kinase chr21 Not Cancer Driver No 1 intact 93 327 46 46 0
IARS1-203 IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 Not Cancer Driver No 4 intact 99 28 2 2 4
IKBKB-216 IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 intact 83 211 22 22 1
IKBKE-203 IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact 90 76 10 10 0
KARS1-201 KARS1 Q15046 Lysine--tRNA ligase chr16 Not Cancer Driver No 3 intact 67 160 11 11 12
LARS1-201 LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 90 97 7 7 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 2 intact 402 91 13 13 20
MAP3K14-201 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 intact 0 543 0 0 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact 74 333 42 42 6
MAPK13-201 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact 34 50 11 11 0
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact 104 593 69 69 0
MST1R-201 MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 intact 147 183 24 24 1
NCAPH2-205 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 1 intact 48 338 26 26 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact 119 117 40 40 0
NELFCD-214 NELFCD Q8IXH7 Negative elongation factor C/D chr20 Not Cancer Driver No 1 intact 50 52 3 3 0
NFKB2-211 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact 61 513 34 34 0
NFKBIB-201 NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 1 intact 31 224 24 24 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact 25 249 19 19 0
PDCD11-201 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 1 intact 167 487 49 49 0
PKN2-203 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 Not Cancer Driver No 1 intact 76 415 29 29 0
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact 129 925 106 106 0
QARS1-201 QARS1 P47897 Glutamine--tRNA ligase chr3 Not Cancer Driver No 1 intact 65 106 10 10 4
RARS1-201 RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 2 intact 54 42 3 3 2
RELA-202 RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 intact 53 401 32 32 0
RELB-201 RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 intact 45 348 27 27 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact 64 420 31 31 0
RIPK3-201 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact 47 295 27 27 0
RMC1-201 RMC1 Q96DM3 Regulator of MON1-CCZ1 complex chr18 Not Cancer Driver No 1 intact 51 12 0 0 0
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 intact 23 17 1 1 0
SDHA-201 SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact 87 72 9 9 7
SMARCB1-213 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact 55 141 26 26 3
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SOAT1-201 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact 55 51 1 1 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact 62 233 23 23 0
TFE3-201 TFE3 P19532 Transcription factor E3 chrX Census Yes 1 intact 44 526 41 41 9
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact 152 110 21 21 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact 25 36 4 4 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact 19 81 7 7 0