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ESRRG-209 ,ESRRG ,P62508
  • Number of Interaction partner in intact: 38
  • Number of Interaction partner in biogrid: 11
  • Number of Interaction partner in hippie: 79
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOT4-201 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 Not Cancer Driver No 1 hippie, biogrid 42 13 1 1 0
ADCY4-202 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 Not Cancer Driver No 1 intact, hippie 100 94 18 18 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARHGEF15-201 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 Not Cancer Driver No 1 hippie 119 538 81 81 0
ATM-229 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 intact, hippie 358 226 29 29 41
BPHL-203 BPHL Q86WA6 Valacyclovir hydrolase chr6 Not Cancer Driver No 1 intact, hippie 22 12 0 0 0
C22orf23-203 C22orf23 Q9BZE7 UPF0193 protein EVG1 chr22 Not Cancer Driver No 1 intact, hippie 26 181 22 22 0
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CAMK2G-207 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 Not Cancer Driver No 1 intact, hippie 43 182 6 6 1
CCDC33-212 CCDC33 Q8N5R6 Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 1 hippie 100 621 57 57 0
CCL8-201 CCL8 P80075 C-C motif chemokine 8 chr17 Not Cancer Driver No 1 intact 12 0 0 0 0
CREBZF-204 CREBZF Q9NS37 CREB/ATF bZIP transcription factor chr11 Not Cancer Driver No 1 hippie 32 279 27 27 0
DAXX-202 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 hippie 79 549 57 57 0
DDX3Y-201 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY Not Cancer Driver No 1 hippie, biogrid 27 289 16 16 0
DEUP1-201 DEUP1 Q05D60 Deuterosome assembly protein 1 chr11 Not Cancer Driver No 1 hippie 70 396 44 44 0
DNMT3L-204 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 1 hippie 65 10 0 0 0
DPF2-205 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 49 179 21 21 5
DUT-201 DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 Not Cancer Driver No 1 hippie 12 128 6 6 1
EBP-205 EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 hippie 22 9 0 0 7
EFHC2-202 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX Not Cancer Driver No 1 intact, hippie 65 50 7 7 0
EIF3I-224 EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 hippie 38 46 5 5 0
ENST00000640655 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie, biogrid 92 721 45 45 0
ESRRA-201 ESRRA P11474 Steroid hormone receptor ERR1 chr11 Compendium Yes 2 hippie, biogrid 27 101 9 9 0
ESRRB-208 ESRRB O95718 Steroid hormone receptor ERR2 chr14 Not Cancer Driver No 2 hippie, biogrid 71 41 7 7 4
ESRRG-209 ESRRG P62508 Estrogen-related receptor gamma chr1 Not Cancer Driver No 3 intact, hippie 112 77 20 20 0
EXOSC7-201 EXOSC7 Q15024 Exosome complex component RRP42 chr3 Not Cancer Driver No 1 hippie 30 8 1 1 0
FAM107A-201 FAM107A O95990 Actin-associated protein FAM107A chr3 Not Cancer Driver No 1 intact, hippie 19 140 18 18 0
FAM9A-201 FAM9A Q8IZU1 Protein FAM9A chrX Not Cancer Driver No 1 intact, hippie 35 333 35 35 0
FASTK-201 FASTK Q14296 Fas-activated serine/threonine kinase chr7 Not Cancer Driver No 1 intact, hippie 56 143 13 13 0
HGS-201 HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 83 535 62 62 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
IFNA5-201 IFNA5 P01569 Interferon alpha-5 chr9 Not Cancer Driver No 1 intact 27 1 0 0 0
IL12B-201 IL12B P29460 Interleukin-12 subunit beta chr5 Not Cancer Driver No 1 intact 37 42 1 1 0
IL17A-201 IL17A Q16552 Interleukin-17A chr6 Not Cancer Driver No 1 intact 45 56 16 16 0
IL31-201 IL31 Q6EBC2 Interleukin-31 chr12 Not Cancer Driver No 1 intact 14 26 2 2 0
ISCA1-203 ISCA1 Q9BUE6 Iron-sulfur cluster assembly 1 homolog, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 1 11 0 0 0
KIFC3-201 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 intact, hippie 60 488 34 34 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
MEOX2-201 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 59 275 53 53 0
MFHAS1-201 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 Not Cancer Driver No 1 intact, hippie 72 98 8 8 0
MRE11-201 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 61 292 28 28 1
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 27 106 8 8 0
NBN-201 NBN O60934 Nibrin chr8 Census Yes 1 hippie, biogrid 63 420 45 45 1
NCOA1-202 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 Census, Compendium Yes 1 hippie 135 1217 107 107 0
NR0B1-202 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX Not Cancer Driver No 4 intact, hippie 74 97 15 15 16
NR0B2-201 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 Not Cancer Driver No 3 intact, hippie 30 10 2 2 0
NRIP1-201 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 Not Cancer Driver No 1 hippie 102 1001 91 91 0
NUP160-212 NUP160 Q12769 Nuclear pore complex protein Nup160 chr11 Not Cancer Driver No 1 intact, hippie 103 48 1 1 0
PAX6-203 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 51 338 37 37 35
PNRC1-201 PNRC1 Q12796 Proline-rich nuclear receptor coactivator 1 chr6 Not Cancer Driver No 1 hippie 26 312 25 25 0
PNRC2-201 PNRC2 Q9NPJ4 Proline-rich nuclear receptor coactivator 2 chr1 Not Cancer Driver No 2 intact, hippie 1 122 1 1 0
POMC-203 POMC P01189 Pro-opiomelanocortin chr2 Not Cancer Driver No 1 intact, hippie 28 200 23 23 0
PPARGC1A-201 PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 Not Cancer Driver No 1 hippie 91 613 85 85 0
PPARGC1B-201 PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 Not Cancer Driver No 3 intact, hippie, biogrid 96 849 77 77 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PROX1-201 PROX1 Q92786 Prospero homeobox protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 151 539 116 116 0
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 3 intact, hippie 35 64 5 5 0
RAD50-201 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie, biogrid 106 730 50 50 0
RBIS-213 RBIS Q8N0T1 Ribosomal biogenesis factor chr8 Not Cancer Driver No 1 intact 4 70 2 2 0
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 53 365 35 35 0
RINT1-201 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 58 55 2 2 2
SAE1-201 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 Not Cancer Driver No 1 hippie 26 90 4 4 0
SHTN1-202 SHTN1 A0MZ66 Shootin-1 chr10 Census Yes 2 intact, hippie 52 471 42 42 0
SNIP1-201 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 45 286 32 32 1
SP1-201 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 67 601 53 53 0
SRA1-201 SRA1 Q9HD15 Steroid receptor RNA activator 1 chr5 Not Cancer Driver No 1 hippie 14 174 11 11 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
SRPK1-204 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie 52 329 21 21 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 6 86 4 4 0
TLE1-203 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 hippie 86 385 39 39 0
TNNI1-202 TNNI1 P19237 Troponin I, slow skeletal muscle chr1 Not Cancer Driver No 1 hippie 26 72 4 4 0
TNNI2-204 TNNI2 P48788 Troponin I, fast skeletal muscle chr11 Not Cancer Driver No 1 intact, hippie 36 171 35 35 1
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie, biogrid 2742 282 1364 1364 60
TRERF1-204 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 Not Cancer Driver No 1 intact, hippie 179 956 134 134 0
TULP3-202 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 intact, hippie 54 218 26 26 1
UBA2-201 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie 62 221 22 22 4
UBE2I-203 UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 intact, hippie 16 16 3 3 0
UBL7-202 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 Not Cancer Driver No 1 hippie 25 192 18 18 0
VAX1-202 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 Not Cancer Driver No 1 intact, hippie 34 234 23 23 1
ZNF438-205 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 94 614 71 71 0