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FBXO28-201 ,FBXO28 ,Q9NVF7
  • Number of Interaction partner in intact: 50
  • Number of Interaction partner in biogrid: 62
  • Number of Interaction partner in hippie: 91
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGGF1-201 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 Not Cancer Driver No 1 hippie 68 583 60 60 1
ANGPT2-201 ANGPT2 O15123 Angiopoietin-2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 44 96 7 7 1
ANGPTL3-201 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 35 154 19 19 0
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 3 hippie, biogrid 106 224 28 28 0
ARHGEF7-206 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 67 302 30 30 0
BLOC1S6-201 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 Not Cancer Driver No 1 hippie, biogrid 10 111 10 10 0
BRAP-202 BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 intact, hippie 54 193 16 16 0
CAPZB-201 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 17 66 1 1 0
CAVIN1-201 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 Not Cancer Driver No 2 intact, hippie 48 281 34 34 0
CCBE1-201 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 73 227 49 49 5
CCDC89-201 CCDC89 Q8N998 Coiled-coil domain-containing protein 89 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 47 190 19 19 0
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 44 412 36 36 0
CLEC11A-201 CLEC11A Q9Y240 C-type lectin domain family 11 member A chr19 Not Cancer Driver No 3 intact, hippie, biogrid 22 184 18 18 0
CLEC4F-201 CLEC4F Q8N1N0 C-type lectin domain family 4 member F chr2 Not Cancer Driver No 1 hippie, biogrid 103 250 44 44 0
CLEC4G-201 CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 hippie, biogrid 32 35 3 3 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 47 75 6 6 4
CTNNA3-203 CTNNA3 Q9UI47 Catenin alpha-3 chr10 Not Cancer Driver No 1 intact, hippie 225 187 37 37 1
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 127 65 9 9 0
DCTN2-209 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 34 254 23 23 0
EGFL8-219 EGFL8 Q99944 Epidermal growth factor-like protein 8 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 32 56 8 8 0
EMILIN1-201 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 89 671 50 50 1
EMILIN3-201 EMILIN3 Q9NT22 EMILIN-3 chr20 Not Cancer Driver No 1 intact, hippie 76 339 33 33 0
EML1-201 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 113 205 25 25 2
EML4-201 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 Census, Compendium Yes 2 hippie, biogrid 78 387 33 33 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
EXOC7-202 EXOC7 Q9UPT5 Exocyst complex component 7 chr17 Not Cancer Driver No 1 intact, hippie 79 209 22 22 0
FAM81A-201 FAM81A Q8TBF8 Protein FAM81A chr15 Not Cancer Driver No 1 hippie, biogrid 36 157 9 9 0
FBXO28-201 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 1 intact, hippie 28 230 15 15 1
FGFR1OP2-201 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 1 hippie, biogrid 18 188 15 15 0
GCC1-201 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 83 511 48 48 0
GIT1-201 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 48 434 26 26 0
GIT2-202 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 2 hippie, biogrid 59 494 36 36 0
GK-206 GK P32189 Glycerol kinase chrX Not Cancer Driver No 1 intact, hippie 50 15 2 2 3
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 3 intact, hippie 84 859 71 71 0
GOLGA6L9-202 GOLGA6L9 A6NEM1 Golgin subfamily A member 6-like protein 9 chr15 Not Cancer Driver No 1 intact, hippie 0 355 0 0 0
GOPC-202 GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 2 intact, hippie, biogrid 40 263 27 27 0
HOMER1-202 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 32 243 28 28 0
HOMER3-202 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 14 254 7 7 0
HSF4-215 HSF4 Q9ULV5 Heat shock factor protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 29 327 17 17 4
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 70 255 29 29 0
IKBIP-202 IKBIP Q70UQ0 Inhibitor of nuclear factor kappa-B kinase-interacting protein chr12 Not Cancer Driver No 2 intact, hippie, biogrid 31 70 7 7 0
ITM2B-204 ITM2B Q9Y287 Integral membrane protein 2B chr13 Not Cancer Driver No 1 intact 15 12 0 0 1
KPNA1-201 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie, biogrid 48 122 16 16 0
KRT80-202 KRT80 Q6KB66 Keratin, type II cytoskeletal 80 chr12 Not Cancer Driver No 1 hippie, biogrid 39 150 13 13 0
LDHD-201 LDHD Q86WU2 Probable D-lactate dehydrogenase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 47 48 7 7 2
LRRCC1-201 LRRCC1 Q9C099 Leucine-rich repeat and coiled-coil domain-containing protein 1 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 103 415 42 42 0
LSMEM1-201 LSMEM1 Q8N8F7 Leucine-rich single-pass membrane protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 10 17 0 0 0
LURAP1L-201 LURAP1L Q8IV03 Leucine rich adaptor protein 1-like chr9 Not Cancer Driver No 3 intact, hippie, biogrid 24 143 13 13 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 78 85 10 10 0
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MCUR1-201 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 66 0 0 0
NCKIPSD-201 NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 Census Yes 2 intact, hippie, biogrid 53 260 23 23 0
NEDD1-201 NEDD1 Q8NHV4 Protein NEDD1 chr12 Not Cancer Driver No 3 hippie, biogrid 65 282 29 29 0
NLRP3-201 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 1 intact, hippie 287 65 30 30 34
NUP50-201 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 43 335 30 30 0
NUP58-202 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 intact, hippie 48 379 35 35 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 36 300 19 19 2
PAK2-201 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 3 hippie, biogrid 61 242 31 31 1
PFDN4-201 PFDN4 Q9NQP4 Prefoldin subunit 4 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 13 41 3 3 0
PLEKHF2-201 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 18 36 0 0 0
PMF1-202 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 7 76 1 1 0
PMF1-BGLAP-203 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 7 100 1 1 0
POC1B-201 POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 2 intact, hippie, biogrid 44 86 6 6 1
PPP4R3A-206 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 Not Cancer Driver No 1 intact, hippie 59 255 20 20 0
PSMB1-201 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie, biogrid 20 15 2 2 0
PSMC3-201 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 4 intact, hippie, biogrid 38 131 8 8 0
RAB11FIP4-211 RAB11FIP4 Q86YS3 Rab11 family-interacting protein 4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 57 437 44 44 0
RASEF-202 RASEF Q8IZ41 Ras and EF-hand domain-containing protein chr9 Not Cancer Driver No 1 hippie, biogrid 74 373 37 37 0
RHOU-201 RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 28 63 6 6 0
SDCBP2-202 SDCBP2 Q9H190 Syntenin-2 chr20 Not Cancer Driver No 1 hippie 36 69 8 8 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 2 intact, hippie, biogrid 65 532 49 49 0
SKP1-202 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 8 intact, hippie, biogrid 20 96 19 19 0
SOX13-203 SOX13 Q9UN79 Transcription factor SOX-13 chr1 Not Cancer Driver No 1 hippie, biogrid 67 566 59 59 0
SPAG5-201 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 intact, hippie 95 636 59 59 0
STX1B-201 STX1B P61266 Syntaxin-1B chr16 Not Cancer Driver No 1 hippie 30 156 18 18 2
STXBP4-201 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 58 212 20 20 0
SUN1-203 SUN1 O94901 SUN domain-containing protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 81 247 26 26 0
SYNGAP1-229 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 Not Cancer Driver No 1 hippie, biogrid 113 833 66 66 4
TAX1BP3-201 TAX1BP3 O14907 Tax1-binding protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 12 52 5 5 0
TCP10L-201 TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 23 216 23 23 0
TMCC3-201 TMCC3 Q9ULS5 Transmembrane and coiled-coil domain protein 3 chr12 Not Cancer Driver No 2 hippie, biogrid 67 255 42 42 0
TMED9-201 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 12 22 2 2 0
TMEM266-201 TMEM266 Q2M3C6 Transmembrane protein 266 chr15 Not Cancer Driver No 1 intact, hippie 62 242 25 25 0
TOP2A-201 TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 115 509 46 46 0
TRAF1-201 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 38 63 4 4 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 4 intact, hippie, biogrid 51 4 1 1 0
TRAF5-201 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 2 hippie, biogrid 46 59 4 4 0
TRAF7-201 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 Census Yes 2 intact, hippie, biogrid 65 121 13 13 4
TTC9C-202 TTC9C Q8N5M4 Tetratricopeptide repeat protein 9C chr11 Not Cancer Driver No 1 hippie, biogrid 13 81 3 3 0
ZNF7-216 ZNF7 P17097 Zinc finger protein 7 chr8 Not Cancer Driver No 1 hippie, biogrid 50 159 10 10 0
ZWINT-203 ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie, biogrid 49 170 36 36 0