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FBXO42-201 ,FBXO42 ,Q6P3S6
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 14
  • Number of Interaction partner in hippie: 30
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
CCDC6-201 CCDC6 Q16204 Coiled-coil domain-containing protein 6 chr10 Census, Compendium Yes 2 hippie, biogrid 48 373 40 40 0
COPS6-201 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie 23 30 4 4 0
CST1-201 CST1 P01037 Cystatin-SN chr20 Not Cancer Driver No 1 intact, hippie, biogrid 27 0 0 0 0
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 127 65 9 9 0
DDX1-201 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 hippie 59 91 10 10 0
DNM2-201 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 95 271 32 32 16
GJA10-201 GJA10 Q969M2 Gap junction alpha-10 protein chr6 Not Cancer Driver No 1 hippie, biogrid 94 210 28 28 0
GSK3A-201 GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 3 intact, hippie, biogrid 33 180 5 5 0
HDLBP-201 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie 143 555 61 61 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
ITCH-201 ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 75 335 33 33 0
KLK6-201 KLK6 Q92876 Kallikrein-6 chr19 Not Cancer Driver No 2 hippie, biogrid 56 28 9 9 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 74 333 42 42 6
NDUFV1-201 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie 45 57 3 3 3
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
PPP4C-201 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 0
PPP4R1-203 PPP4R1 Q8TF05 Serine/threonine-protein phosphatase 4 regulatory subunit 1 chr18 Not Cancer Driver No 1 hippie, biogrid 68 305 11 11 0
RAB28-202 RAB28 P51157 Ras-related protein Rab-28 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 27 27 5 5 0
RBPJ-206 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 3 intact, hippie, biogrid 32 151 10 10 2
RBX1-201 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 2 hippie, biogrid 9 18 1 1 0
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 50 20 1 1 0
ROCK2-202 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 110 734 61 61 0
SKP1-202 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 4 intact, hippie, biogrid 20 96 19 19 0
SMURF1-201 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 60 257 19 19 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 hippie 62 233 23 23 0
TAB2-208 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 Not Cancer Driver No 1 hippie 61 573 51 51 2
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TPP1-201 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 Not Cancer Driver No 1 hippie 56 92 7 7 34
TTC9C-202 TTC9C Q8N5M4 Tetratricopeptide repeat protein 9C chr11 Not Cancer Driver No 1 hippie, biogrid 13 81 3 3 0
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40