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FDPS-202 ,FDPS ,P14324
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 76
  • Number of Interaction partner in hippie: 84
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCE1-201 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 50 36 4 4 0
ABHD16A-201 ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 Not Cancer Driver No 1 hippie 53 53 11 11 2
ACAA2-201 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 32 52 1 1 0
AGMAT-201 AGMAT Q9BSE5 Guanidino acid hydrolase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 40 106 8 8 0
AIFM3-207 AIFM3 Q96NN9 Apoptosis-inducing factor 3 chr22 Not Cancer Driver No 1 hippie, biogrid 64 66 12 12 0
ALAS1-205 ALAS1 P13196 5-aminolevulinate synthase, non-specific, mitochondrial chr3 Not Cancer Driver No 2 hippie, biogrid 39 178 9 9 0
ARIH1-201 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 1 biogrid 27 119 1 1 2
ATP6AP1-201 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 1 biogrid 52 0 0 0 4
ATP6V1G1-201 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 Not Cancer Driver No 1 biogrid 9 91 5 5 0
ATPAF2-206 ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 chr17 Not Cancer Driver No 2 hippie, biogrid 20 66 3 3 1
ATXN1-202 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 111 608 91 91 0
BASP1-201 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 12 227 12 12 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie 27 104 13 13 0
BCL2L14-203 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 20 40 4 4 0
BDP1-201 BDP1 A6H8Y1 Transcription factor TFIIIB component B'' homolog chr5 Not Cancer Driver No 1 biogrid 203 2498 193 193 0
BNIP1-202 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 Not Cancer Driver No 1 biogrid 31 57 7 7 0
BOD1L1-201 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 biogrid 276 3030 276 276 0
CCNK-201 CCNK O75909 Cyclin-K chr14 Not Cancer Driver No 1 biogrid 27 347 9 9 1
CDC27-201 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 70 289 26 26 0
CDK12-202 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 Census, Compendium Yes 1 biogrid 142 1203 92 92 0
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CLIC4-201 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 23 49 4 4 0
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 15 83 7 7 3
CREB3-201 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 25 169 7 7 0
CTH-202 CTH P32929 Cystathionine gamma-lyase chr1 Not Cancer Driver No 1 hippie, biogrid 31 50 3 3 2
DDR1-225 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 98 253 41 41 0
DPH2-201 DPH2 Q9BQC3 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 59 177 23 23 1
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF3H-209 EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 biogrid 24 109 7 7 0
EIF4ENIF1-201 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 86 902 75 75 0
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 biogrid 77 61 4 4 2
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 biogrid 38 29 2 2 0
EMC4-202 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 biogrid 8 17 1 1 0
EMC6-201 EMC6 Q9BV81 ER membrane protein complex subunit 6 chr17 Not Cancer Driver No 1 biogrid 3 0 0 0 0
EMC7-201 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 1 biogrid 22 54 4 4 0
EPHX2-207 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 Not Cancer Driver No 1 hippie, biogrid 56 26 2 2 0
FDPS-202 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 2 intact, hippie, biogrid 50 0 0 0 1
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 92 231 26 26 69
G6PD-202 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 1 hippie, biogrid 64 28 3 3 51
GLDC-201 GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 Not Cancer Driver No 2 hippie, biogrid 105 112 6 6 22
GPX1-202 GPX1 P07203 Glutathione peroxidase 1 chr3 Not Cancer Driver No 1 hippie, biogrid 22 12 3 3 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 21 10 0 0 0
HIBADH-201 HIBADH P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 7 0 0 0
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 24 78 5 5 0
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 290 22 22 4
HNRNPA1L2-201 HNRNPA1L2 Q32P51 Heterogeneous nuclear ribonucleoprotein A1-like 2 chr13 Not Cancer Driver No 1 hippie, biogrid 11 235 6 6 0
HNRNPA3-201 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie, biogrid 20 285 13 13 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 82 252 28 28 0
HUS1-201 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 19 17 1 1 0
IDH1-201 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 Census, Compendium Yes 1 hippie 522 37 2 2 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie, biogrid 143 265 30 30 6
IMPDH2-201 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 52 6 1 1 0
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 88 408 46 46 0
LILRB3-206 LILRB3 O75022 Leukocyte immunoglobulin-like receptor subfamily B member 3 chr19 Not Cancer Driver No 1 hippie 54 296 39 39 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MBTPS2-202 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 41 16 3 3 9
MCFD2-201 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 9 9 4
MED23-205 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 biogrid 109 28 3 3 1
MED9-201 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 1 biogrid 13 127 12 12 0
MMAB-210 MMAB Q96EY8 Corrinoid adenosyltransferase MMAB chr12 Not Cancer Driver No 1 hippie, biogrid 26 69 9 9 5
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NDUFAF5-202 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 2 hippie, biogrid 36 69 11 11 3
NIP7-201 NIP7 Q9Y221 60S ribosome subunit biogenesis protein NIP7 homolog chr16 Not Cancer Driver No 1 biogrid 12 1 0 0 0
NME1-203 NME1 P15531 Nucleoside diphosphate kinase A chr17 Not Cancer Driver No 1 hippie 9 10 0 0 0
NME2-205 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
NMRAL1-201 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 28 14 2 2 0
NPEPPS-201 NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 Compendium Yes 1 hippie, biogrid 69 45 2 2 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 25 34 3 3 0
PABPC1-201 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie, biogrid 53 317 32 32 0
PCYOX1-204 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 Not Cancer Driver No 2 hippie, biogrid 37 9 1 1 0
PDSS1-201 PDSS1 Q5T2R2 All trans-polyprenyl-diphosphate synthase PDSS1 chr10 Not Cancer Driver No 2 hippie, biogrid 37 52 7 7 1
PDSS2-202 PDSS2 Q86YH6 All trans-polyprenyl-diphosphate synthase PDSS2 chr6 Not Cancer Driver No 2 hippie, biogrid 27 7 0 0 1
PLAA-201 PLAA Q9Y263 Phospholipase A-2-activating protein chr9 Not Cancer Driver No 1 hippie, biogrid 56 152 11 11 2
PLS3-202 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie 63 75 5 5 0
PMVK-201 PMVK Q15126 Phosphomevalonate kinase chr1 Not Cancer Driver No 1 biogrid 29 3 0 0 0
PPME1-201 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie 28 146 8 8 0
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 biogrid 169 0 0 0 4
PRNP-201 PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 28 117 8 8 19
PSME4-202 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 Not Cancer Driver No 2 hippie, biogrid 156 134 11 11 0
PYGM-201 PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie, biogrid 114 39 3 3 17
RINT1-201 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 biogrid 58 55 2 2 2
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RNF19B-203 RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 1 hippie 45 344 20 20 0
RPL31-201 RPL31 P62899 Large ribosomal subunit protein eL31 chr2 Not Cancer Driver No 1 hippie 13 69 10 10 0
RRM1-201 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 Not Cancer Driver No 1 biogrid 54 41 5 5 0
SEC31A-205 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 hippie, biogrid 103 520 44 44 0
SEPHS1-201 SEPHS1 P49903 Selenide, water dikinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 29 6 6 0
SLC30A2-201 SLC30A2 Q9BRI3 Proton-coupled zinc antiporter SLC30A2 chr1 Not Cancer Driver No 1 hippie 48 47 5 5 2
SORD-201 SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie 22 41 4 4 3
SPARC-201 SPARC P09486 SPARC chr5 Not Cancer Driver No 1 hippie, biogrid 39 70 2 2 2
SSMEM1-201 SSMEM1 Q8WWF3 Serine-rich single-pass membrane protein 1 chr7 Not Cancer Driver No 1 hippie 36 183 25 25 0
STAMBP-202 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie 42 143 15 15 6
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
TAF1A-202 TAF1A Q15573 TATA box-binding protein-associated factor RNA polymerase I subunit A chr1 Not Cancer Driver No 1 biogrid 32 29 2 2 0
TAF2-201 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 biogrid 83 242 21 21 1
TAGLN-202 TAGLN Q01995 Transgelin chr11 Not Cancer Driver No 1 hippie 12 94 8 8 0
TALDO1-201 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 1 hippie 34 31 3 3 1
TCOF1-207 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 biogrid 107 1462 109 109 1
TEX101-201 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 39 2 0 0 0
TIMELESS-203 TIMELESS Q9UNS1 Protein timeless homolog chr12 Not Cancer Driver No 1 biogrid 127 371 44 44 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRNAU1AP-201 TRNAU1AP Q9NX07 tRNA selenocysteine 1-associated protein 1 chr1 Not Cancer Driver No 1 biogrid 19 32 2 2 0
TRRAP-202 TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 biogrid 431 402 47 47 8
TSG101-201 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 hippie 31 160 15 15 0
TTC19-201 TTC19 Q6DKK2 Tetratricopeptide repeat protein 19, mitochondrial chr17 Not Cancer Driver No 2 hippie, biogrid 20 76 1 1 0
TTC38-201 TTC38 Q5R3I4 Tetratricopeptide repeat protein 38 chr22 Not Cancer Driver No 1 hippie, biogrid 46 37 3 3 0
UBA2-201 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 biogrid 62 221 22 22 4
USE1-201 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 biogrid 27 102 19 19 0
VPS29-206 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 biogrid 15 0 0 0 0
WDR7-201 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 biogrid 164 292 28 28 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 biogrid 25 42 2 2 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 2 hippie, biogrid 84 33 5 5 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 2 hippie, biogrid 46 23 0 0 3