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FLAD1-201 ,FLAD1 ,Q8NFF5
  • Number of Interaction partner in intact: 13
  • Number of Interaction partner in biogrid: 45
  • Number of Interaction partner in hippie: 101
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2-201 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 91 203 23 23 5
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 54 28 2 2 12
ANKRD39-201 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 Not Cancer Driver No 1 hippie, biogrid 14 38 1 1 0
ANXA7-201 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie 0 0 0 0 0
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 23 104 9 9 0
APTX-203 APTX Q7Z2E3 Aprataxin chr9 Not Cancer Driver No 1 intact, hippie 19 113 6 6 9
AUH-202 AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 29 0 0 1
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie, biogrid 83 546 51 51 10
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 5 5 2
CCL18-201 CCL18 P55774 C-C motif chemokine 18 chr17 Not Cancer Driver No 1 hippie, biogrid 9 0 0 0 0
CDC25C-201 CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 48 226 19 19 0
CDKN1A-201 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 38 121 25 25 0
CELA2A-201 CELA2A P08217 Chymotrypsin-like elastase family member 2A chr1 Not Cancer Driver No 1 hippie, biogrid 36 4 4 4 2
CLVS2-201 CLVS2 Q5SYC1 Clavesin-2 chr6 Not Cancer Driver No 1 intact, hippie 97 81 23 23 0
COPS3-201 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 36 67 7 7 0
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CRABP2-203 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 Not Cancer Driver No 1 intact, hippie 24 23 5 5 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 38 13 2 2 0
DNM2-201 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 95 271 32 32 16
DUS1L-201 DUS1L Q6P1R4 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like chr17 Not Cancer Driver No 1 hippie, biogrid 44 110 9 9 0
DUSP14-206 DUSP14 O95147 Dual specificity protein phosphatase 14 chr17 Not Cancer Driver No 1 hippie 20 15 1 1 0
DUSP9-201 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 33 109 12 12 0
EYA4-202 EYA4 O95677 Eyes absent homolog 4 chr6 Not Cancer Driver No 1 hippie 142 339 81 81 2
FLAD1-201 FLAD1 Q8NFF5 FAD synthase chr1 Not Cancer Driver No 2 intact, hippie 66 59 8 8 1
FOXD3-201 FOXD3 Q9UJU5 Forkhead box protein D3 chr1 Not Cancer Driver No 1 hippie, biogrid 22 263 12 12 0
FSCN3-201 FSCN3 Q9NQT6 Fascin-3 chr7 Not Cancer Driver No 2 hippie, biogrid 84 6 0 0 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 1 hippie 63 312 40 40 0
GEMIN4-201 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 hippie 75 24 1 1 0
GFM1-210 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 49 79 5 5 4
GOLGA6L2-202 GOLGA6L2 Q8N9W4 Golgin subfamily A member 6-like protein 2 chr15 Not Cancer Driver No 1 hippie 15 830 11 11 0
GRB7-201 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 hippie 61 134 18 18 0
HINT2-201 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 6 29 1 1 0
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 23 25 3 3 0
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 45 83 1 1 2
IMMP1L-209 IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 15 3 0 0 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
ISCA1-203 ISCA1 Q9BUE6 Iron-sulfur cluster assembly 1 homolog, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 1 11 0 0 0
KDM6B-202 KDM6B O15054 Lysine-specific demethylase 6B chr17 Not Cancer Driver No 1 hippie 151 1288 116 116 2
KLHL14-202 KLHL14 Q9P2G3 Kelch-like protein 14 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 94 81 10 10 0
L3MBTL3-201 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 1 intact, hippie 95 351 49 49 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MCUR1-201 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 66 0 0 0
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
MDP1-201 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 Not Cancer Driver No 1 hippie 18 34 5 5 0
METTL17-201 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 48 95 10 10 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MRPL58-201 MRPL58 Q14197 Large ribosomal subunit protein mL62 chr17 Not Cancer Driver No 1 hippie 26 106 11 11 0
MRPS26-201 MRPS26 Q9BYN8 Small ribosomal subunit protein mS26 chr20 Not Cancer Driver No 1 hippie, biogrid 12 102 4 4 0
MRRF-202 MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 13 118 6 6 0
MTIF3-202 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 15 180 11 11 0
MTMR14-201 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 45 150 6 6 2
NIF3L1-202 NIF3L1 Q9GZT8 NIF3-like protein 1 chr2 Not Cancer Driver No 1 hippie 38 43 1 1 0
NUDT21-201 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie 15 37 2 2 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OTP-201 OTP Q5XKR4 Homeobox protein orthopedia chr5 Not Cancer Driver No 1 hippie, biogrid 30 279 24 24 0
PDE6H-201 PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 Not Cancer Driver No 1 hippie, biogrid 16 60 15 15 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 32 49 7 7 0
PFAS-201 PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 Not Cancer Driver No 1 hippie, biogrid 128 381 33 33 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHO2-201 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 48 404 46 46 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 48 23 3 3 4
PRTFDC1-201 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 2 intact, hippie 20 3 0 0 0
PSG1-204 PSG1 P11464 Pregnancy-specific beta-1-glycoprotein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 103 78 16 16 0
PSPH-201 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 1 hippie, biogrid 31 21 2 2 3
PTP4A1-203 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 Not Cancer Driver No 1 hippie 11 2 0 0 0
PTP4A2-219 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 Not Cancer Driver No 1 hippie 13 3 0 0 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 36 141 17 17 0
RB1CC1-201 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 150 579 56 56 0
RCC1-214 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 44 146 16 16 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 2 intact, hippie 53 365 35 35 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
SCGB1C1-201 SCGB1C1 Q8TD33 Secretoglobin family 1C member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 23 17 1 1 0
SH3GLB1-201 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 82 6 6 0
SIRT4-201 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 31 4 0 0 0
SMAD4-201 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 172 195 16 16 6
SORD-201 SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie, biogrid 22 41 4 4 3
SPANXN4-202 SPANXN4 Q5MJ08 Sperm protein associated with the nucleus on the X chromosome N4 chrX Not Cancer Driver No 1 hippie, biogrid 10 99 10 10 0
ST7-201 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie, biogrid 37 64 6 6 0
TAFA3-201 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 Not Cancer Driver No 1 intact, hippie 13 6 0 0 0
TBRG4-201 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 56 61 1 1 0
TCF4-202 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 105 662 104 104 10
TK1-201 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 hippie 19 13 3 3 0
TKFC-201 TKFC Q3LXA3 Triokinase/FMN cyclase chr11 Not Cancer Driver No 1 hippie 45 93 9 9 2
TNRC6B-206 TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 1 hippie 149 1735 140 140 0
TNS2-201 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 97 800 47 47 0
TRAP1-201 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 110 6 6 0
TRIM23-201 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 Not Cancer Driver No 2 intact, hippie 65 39 2 2 0
TRUB2-201 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 73 6 6 0
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 36 51 4 4 1
TULP3-202 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 54 218 26 26 1
UBA52-202 UBA52 P62987 Ubiquitin-ribosomal protein eL40 fusion protein chr19 Not Cancer Driver No 1 hippie, biogrid 17 45 8 8 0
UBAP2-204 UBAP2 Q5T6F2 Ubiquitin-associated protein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 44 1040 43 43 0
VWA8-203 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 Not Cancer Driver No 1 hippie, biogrid 153 384 24 24 0
ZNF689-201 ZNF689 Q96CS4 Zinc finger protein 689 chr16 Not Cancer Driver No 1 hippie, biogrid 53 169 11 11 0