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HSPA6-201 ,HSPA6 ,P17066
  • Number of Interaction partner in intact: 73
  • Number of Interaction partner in biogrid: 58
  • Number of Interaction partner in hippie: 237
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ABHD15-201 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 42 42 2 2 0
ABI1-207 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 intact, hippie 37 360 28 28 0
ADCK5-201 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 intact, hippie 39 5 2 2 0
AGBL4-203 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 41 72 0 0 0
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 intact, hippie 41 109 11 11 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 intact, hippie 99 158 19 19 4
ALDH3A2-201 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 30 5 1 1 25
AP2M1-201 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 40 41 7 7 1
ARAF-202 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 61 181 26 26 0
ARRB2-201 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 39 122 19 19 0
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 25 183 12 12 0
AXL-201 AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 131 342 51 51 0
BAD-201 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 10 165 10 10 0
BAG1-210 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 2 hippie, biogrid 19 197 5 5 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie, biogrid 30 572 30 30 7
BAG4-201 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 40 402 36 36 0
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie, biogrid 27 63 5 5 0
BCL3-201 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 intact, hippie 28 259 8 8 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
BRAF-220 BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 intact, hippie 755 311 30 30 35
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
C22orf15-203 C22orf15 Q8WYQ4 Uncharacterized protein C22orf15 chr22 Not Cancer Driver No 1 intact, hippie 13 60 6 6 0
C3orf38-201 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 Not Cancer Driver No 1 hippie, biogrid 28 50 5 5 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 84 513 44 44 4
CCDC117-201 CCDC117 Q8IWD4 Coiled-coil domain-containing protein 117 chr22 Not Cancer Driver No 1 hippie, biogrid 18 257 17 17 0
CCNI2-201 CCNI2 Q6ZMN8 Cyclin-I2 chr5 Not Cancer Driver No 1 hippie, biogrid 13 126 0 0 0
CDC34-201 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 19 96 7 7 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDK20-201 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 1 hippie, biogrid 29 32 1 1 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie, biogrid 40 34 2 2 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 216 145 9 9 130
CISH-201 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 Not Cancer Driver No 1 hippie 29 98 7 7 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CLTA-201 CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie, biogrid 17 194 10 10 0
CLTC-201 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 132 71 5 5 1
CLUAP1-212 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 32 203 17 17 0
COMMD6-213 COMMD6 Q7Z4G1 COMM domain-containing protein 6 chr13 Not Cancer Driver No 1 intact, hippie 8 12 2 2 0
COP1-204 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 hippie 81 148 5 5 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
CPLANE2-201 CPLANE2 Q9BU20 Ciliogenesis and planar polarity effector 2 chr1 Not Cancer Driver No 1 hippie 28 21 3 3 0
CRK-201 CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 24 197 19 19 0
CSK-201 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 intact, hippie 37 18 1 1 0
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 127 65 9 9 0
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
CYP4F12-215 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 Not Cancer Driver No 1 intact, hippie 107 18 2 2 0
DHRS13-201 DHRS13 Q6UX07 Dehydrogenase/reductase SDR family member 13 chr17 Not Cancer Driver No 1 hippie, biogrid 18 101 6 6 0
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie 29 154 13 13 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie 34 174 18 18 0
DNAJA4-202 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 1 hippie 31 111 5 5 0
DNAJB1-201 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 2 hippie, biogrid 26 196 20 20 0
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 41 141 19 19 2
DNAJB2-201 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 Not Cancer Driver No 2 hippie, biogrid 39 239 31 31 1
DNAJB4-201 DNAJB4 Q9UDY4 DnaJ homolog subfamily B member 4 chr1 Not Cancer Driver No 1 intact, hippie 31 160 16 16 0
DNAJB5-210 DNAJB5 O75953 DnaJ homolog subfamily B member 5 chr9 Not Cancer Driver No 1 hippie 35 147 12 12 0
DNAJB6-201 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie 4 198 2 2 3
DNAJB7-201 DNAJB7 Q7Z6W7 DnaJ homolog subfamily B member 7 chr22 Not Cancer Driver No 1 hippie 32 138 17 17 0
DNAJB8-201 DNAJB8 Q8NHS0 DnaJ homolog subfamily B member 8 chr3 Not Cancer Driver No 1 hippie 51 94 21 21 0
DNAJC13-201 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 hippie, biogrid 190 142 13 13 0
DNAJC7-203 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 26 102 8 8 0
DUSP6-201 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 Not Cancer Driver No 1 hippie 33 39 3 3 4
DYRK2-202 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 hippie 60 294 33 33 0
E2F3-201 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 intact, hippie 27 253 11 11 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EIF4B-201 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 80 588 76 76 0
ELK1-203 ELK1 P19419 ETS domain-containing protein Elk-1 chrX Not Cancer Driver No 1 intact, hippie 39 329 26 26 0
ENST00000476049 KRT222 Q8N1A0 Keratin-like protein KRT222 chr17 Not Cancer Driver No 1 intact, hippie 35 132 12 12 0
ENST00000593731 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 1 hippie 83 418 40 40 3
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 69 92 10 10 1
F12-201 F12 P00748 Coagulation factor XII chr5 Not Cancer Driver No 1 hippie, biogrid 51 104 9 9 12
FAF1-201 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 54 241 23 23 0
FAM83F-201 FAM83F Q8NEG4 Protein FAM83F chr22 Not Cancer Driver No 1 hippie, biogrid 50 257 20 20 0
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FBXO38-202 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 94 441 33 33 1
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 92 231 26 26 69
FLNA-202 FLNA P21333 Filamin-A chrX Census Yes 1 hippie 314 1460 162 162 29
FUNDC1-201 FUNDC1 Q8IVP5 FUN14 domain-containing protein 1 chrX Not Cancer Driver No 1 hippie 9 24 0 0 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GAB2-202 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 63 540 53 53 0
GABARAP-201 GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 7 12 0 0 0
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GABARAPL2-201 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 4 2 1 1 0
GAL-201 GAL P22466 Galanin peptides chr11 Not Cancer Driver No 1 hippie, biogrid 14 36 2 2 1
GAN-203 GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 48 33 3 3 20
GNB2-201 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 hippie, biogrid 30 21 0 0 5
GRB10-205 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 Not Cancer Driver No 1 intact, hippie 67 222 30 30 0
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 intact, hippie 89 124 22 22 0
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 30 135 5 5 0
HDAC6-201 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 122 409 35 35 0
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HNRNPD-201 HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 intact, hippie 28 206 12 12 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 44 258 15 15 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 3 hippie, biogrid 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 3 hippie, biogrid 19 200 7 7 0
HSPA1L-201 HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 86 141 23 23 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie, biogrid 50 352 21 21 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 49 282 26 26 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie 82 252 28 28 0
HSPBP1-202 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 26 130 6 6 0
HTRA3-201 HTRA3 P83110 Serine protease HTRA3 chr4 Not Cancer Driver No 1 intact, hippie 47 57 4 4 0
IFT27-205 IFT27 Q9BW83 Intraflagellar transport protein 27 homolog chr22 Not Cancer Driver No 1 hippie 14 0 0 0 1
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 5 301 4 4 21
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie, biogrid 30 72 7 7 0
INPPL1-201 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 1 hippie 146 567 66 66 4
INSIG2-201 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 Not Cancer Driver No 1 hippie 27 11 3 3 0
IQCB1-201 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 Not Cancer Driver No 1 hippie 46 89 6 6 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KIAA1191-201 KIAA1191 Q96A73 Putative monooxygenase p33MONOX chr5 Not Cancer Driver No 1 hippie, biogrid 18 288 15 15 0
KLHL34-201 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 intact, hippie, biogrid 79 77 12 12 0
KNSTRN-201 KNSTRN Q9Y448 Small kinetochore-associated protein chr15 Census Yes 1 hippie 53 248 47 47 0
KRT222-202 KRT222 Q8N1A0 Keratin-like protein KRT222 chr17 Not Cancer Driver No 1 intact, hippie 35 132 12 12 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 76 95 12 12 1
LIME1-201 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 Not Cancer Driver No 1 hippie, biogrid 20 193 14 14 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LRRC28-201 LRRC28 Q86X40 Leucine-rich repeat-containing protein 28 chr15 Not Cancer Driver No 1 hippie, biogrid 39 0 0 0 0
LRRC8E-201 LRRC8E Q6NSJ5 Volume-regulated anion channel subunit LRRC8E chr19 Not Cancer Driver No 1 hippie, biogrid 59 35 0 0 0
MAP1LC3A-201 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 19 24 1 1 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 4 17 0 0 0
MAP2K3-202 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 74 76 19 19 0
MAP2K5-201 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 intact, hippie 26 85 6 6 0
MAP3K1-201 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 Census, Compendium Yes 1 hippie 137 829 43 43 1
MAP3K14-201 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 2 intact, hippie 0 543 0 0 0
MAP3K3-202 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 48 356 27 27 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MCM5-201 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 68 110 15 15 1
MEPCE-201 MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 46 449 29 29 0
MLF2-201 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie 32 189 27 27 0
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie, biogrid 24 45 3 3 0
MOCS3-201 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 52 15 4 4 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYO1D-201 MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 93 61 5 5 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NDRG2-250 NDRG2 Q9UN36 Protein NDRG2 chr14 Not Cancer Driver No 1 hippie, biogrid 43 112 7 7 0
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NEK4-201 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 55 495 40 40 0
NEK8-201 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 intact, hippie 75 167 29 29 3
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 2 intact, hippie 62 345 30 30 0
NFKB2-211 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 61 513 34 34 0
NFX1-203 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 89 492 28 28 0
NOS2-201 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie 147 201 26 26 0
NPHP4-201 NPHP4 O75161 Nephrocystin-4 chr1 Not Cancer Driver No 1 intact, hippie 137 474 44 44 17
NR1I3-204 NR1I3 Q14994 Nuclear receptor subfamily 1 group I member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 46 23 2 2 0
NTNG1-205 NTNG1 Q9Y2I2 Netrin-G1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 124 1 0 0 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
OASL-201 OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 Not Cancer Driver No 1 intact, hippie 58 8 2 2 0
ODF3L1-201 ODF3L1 Q8IXM7 Outer dense fiber protein 3-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 28 122 17 17 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 intact, hippie 36 300 19 19 2
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 148 1147 128 128 2
PDPK1-202 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie 23 121 9 9 0
PELI3-201 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 Not Cancer Driver No 1 hippie, biogrid 38 216 21 21 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PIK3R2-201 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 1 hippie 83 418 40 40 3
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 46 99 8 8 24
PNPLA5-201 PNPLA5 Q7Z6Z6 Patatin-like phospholipase domain-containing protein 5 chr22 Not Cancer Driver No 1 hippie, biogrid 54 33 5 5 0
POC1A-201 POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 2 hippie, biogrid 33 88 6 6 1
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 60 44 3 3 3
PPIB-201 PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 intact, hippie 16 16 0 0 1
PPP5C-201 PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 58 73 10 10 0
PRAP1-201 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 Not Cancer Driver No 1 intact, hippie 10 125 10 10 0
PRDM16-201 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 196 834 117 117 1
PRKCG-201 PRKCG P05129 Protein kinase C gamma type chr19 Not Cancer Driver No 1 intact, hippie 141 152 36 36 4
PRKCI-201 PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 79 120 12 12 0
PRKCZ-201 PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie 47 117 11 11 0
PRODH-203 PRODH O43272 Proline dehydrogenase 1, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie, biogrid 45 64 6 6 17
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PSMB2-201 PSMB2 P49721 Proteasome subunit beta type-2 chr1 Not Cancer Driver No 1 hippie 18 0 0 0 0
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 425 76 5 5 37
PTK6-202 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 31 12 0 0 0
PTMA-201 PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 3 113 3 3 0
PTPN12-201 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 Not Cancer Driver No 1 intact, hippie 68 518 40 40 0
PXN-201 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 intact, hippie 41 342 14 14 0
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 2 intact, hippie 64 169 30 30 18
RANBP9-201 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 42 414 15 15 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RC3H2-202 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 99 704 62 62 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 53 365 35 35 0
RELA-202 RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 53 401 32 32 0
RELB-201 RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 intact, hippie 45 348 27 27 0
RFFL-202 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 Not Cancer Driver No 1 hippie, biogrid 39 151 17 17 0
RFPL2-206 RFPL2 O75678 Ret finger protein-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 57 73 11 11 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RIOK1-202 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 52 303 30 30 0
RIPK2-201 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 intact, hippie 43 143 14 14 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 99 232 31 31 3
RNF185-202 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 Not Cancer Driver No 1 hippie 18 82 10 10 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 45 98 7 7 1
RPAP3-201 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 34 334 20 20 0
RPS6KA1-204 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 71 178 22 22 0
RPS6KA3-201 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 1 hippie 72 146 10 10 13
RPS6KB2-201 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 34 195 8 8 0
SCFD1-203 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 117 9 9 0
SGTB-201 SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 19 114 8 8 0
SHC1-202 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 58 400 41 41 0
SKI-201 SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 41 434 27 27 8
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SNIP1-201 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 45 286 32 32 1
SOCS1-201 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 intact, hippie 20 66 3 3 2
SPDL1-201 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie 59 343 34 34 0
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 49 233 20 20 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 29 113 11 11 11
STYX-201 STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 Not Cancer Driver No 1 intact 13 30 2 2 0
SUPT6H-201 SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 146 761 56 56 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact, hippie 62 233 23 23 0
TEDC1-204 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 Not Cancer Driver No 1 hippie 16 162 4 4 0
TERF1-202 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 51 221 32 32 0
TET2-203 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 150 1671 139 139 1
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 40 169 12 12 0
TLR9-201 TLR9 Q9NR96 Toll-like receptor 9 chr3 Not Cancer Driver No 1 hippie 107 35 3 3 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMPO-202 TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 50 414 32 32 0
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 38 111 14 14 9
TNFRSF1B-201 TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 40 231 21 21 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TPT1-212 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 14 43 5 5 0
TRABD-202 TRABD Q9H4I3 TraB domain-containing protein chr22 Not Cancer Driver No 1 hippie, biogrid 29 67 4 4 0
TRAF3IP1-201 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 46 512 33 33 3
TRIM21-201 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 63 49 8 8 0
TSSK1B-201 TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 75 117 29 29 0
TTC30B-201 IFT70B Q8N4P2 Intraflagellar transport protein 70B chr2 Not Cancer Driver No 1 intact 50 74 9 9 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 45 52 6 6 6
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 51 54 6 6 10
UBASH3A-202 UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 1 hippie 87 27 7 7 0
UBL4A-202 UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 17 16 4 4 0
VASH1-201 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 33 215 14 14 0
VILL-202 VILL O15195 Villin-like protein chr3 Not Cancer Driver No 1 intact, hippie, biogrid 81 224 22 22 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VRK3-201 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 Not Cancer Driver No 1 hippie 52 182 12 12 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
ZBTB18-206 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 62 236 18 18 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 36 929 33 33 0
ZFYVE21-202 ZFYVE21 Q9BQ24 Zinc finger FYVE domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie 22 19 0 0 0
ZNF488-201 ZNF488 Q96MN9 Zinc finger protein 488 chr10 Not Cancer Driver No 1 hippie, biogrid 70 245 53 53 0