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IVL-201 ,IVL ,P07476
  • Number of Interaction partner in intact: 41
  • Number of Interaction partner in biogrid: 104
  • Number of Interaction partner in hippie: 125
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie, biogrid 54 28 2 2 12
ACD-212 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 Not Cancer Driver No 1 hippie 42 257 31 31 1
ACTA2-201 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 1 hippie, biogrid 42 39 3 3 15
AGPAT1-203 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 Not Cancer Driver No 1 hippie, biogrid 27 38 5 5 0
ANKRD36B-202 ANKRD36B Q8N2N9 Ankyrin repeat domain-containing protein 36B chr2 Not Cancer Driver No 1 hippie, biogrid 0 812 0 0 0
ATP6AP2-217 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 2
BLMH-201 BLMH Q13867 Bleomycin hydrolase chr17 Not Cancer Driver No 1 hippie, biogrid 38 15 1 1 0
BPHL-203 BPHL Q86WA6 Valacyclovir hydrolase chr6 Not Cancer Driver No 1 hippie, biogrid 22 12 0 0 0
C18orf21-205 C18orf21 Q32NC0 UPF0711 protein C18orf21 chr18 Not Cancer Driver No 1 hippie, biogrid 12 113 4 4 0
CALML5-201 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 26 101 17 17 0
CASP14-201 CASP14 P31944 Caspase-14 chr19 Not Cancer Driver No 1 hippie, biogrid 42 84 10 10 0
CCNYL1-201 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 21 100 5 5 0
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CDK15-210 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 49 36 3 3 0
CERS3-209 CERS3 Q8IU89 Ceramide synthase 3 chr15 Not Cancer Driver No 1 hippie, biogrid 64 21 9 9 0
CHMP3-201 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 18 138 10 10 0
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 41 84 12 12 0
CSGALNACT1-217 CSGALNACT1 Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 64 132 22 22 3
CSTA-201 CSTA P01040 Cystatin-A chr3 Not Cancer Driver No 1 hippie 12 54 8 8 0
CTSD-201 CTSD P07339 Cathepsin D chr11 Not Cancer Driver No 1 hippie, biogrid 49 6 2 2 2
DDX19B-201 DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 Not Cancer Driver No 2 intact, hippie, biogrid 32 113 6 6 0
DHRS2-201 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 32 0 0 0 0
DKK2-201 DKK2 Q9UBU2 Dickkopf-related protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 84 71 17 17 0
DPPA4-201 DPPA4 Q7L190 Developmental pluripotency-associated protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 76 183 39 39 0
DSP-201 DSP P15924 Desmoplakin chr6 Not Cancer Driver No 1 hippie 354 1127 146 146 6
EEF1A2-201 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie, biogrid 58 121 17 17 3
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 hippie, biogrid 49 179 9 9 21
ELAC2-201 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 69 208 25 25 10
ENST00000443119 DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 Not Cancer Driver No 2 intact, hippie, biogrid 35 116 8 8 0
ERCC3-201 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 Census, Compendium Yes 1 hippie, biogrid 67 208 14 14 2
EVPL-201 EVPL Q92817 Envoplakin chr17 Not Cancer Driver No 1 hippie 225 1220 130 130 0
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FCF1-201 FCF1 Q9Y324 rRNA-processing protein FCF1 homolog chr14 Not Cancer Driver No 2 intact, hippie, biogrid 19 46 3 3 0
FMNL2-201 FMNL2 Q96PY5 Formin-like protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 99 458 49 49 0
FNDC1-201 FNDC1 Q4ZHG4 Fibronectin type III domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 236 1376 205 205 0
FNDC5-201 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 13 74 6 6 0
FRMD1-201 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 74 266 37 37 0
FSTL1-201 FSTL1 Q12841 Follistatin-related protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 36 51 5 5 0
FTH1-201 FTH1 P02794 Ferritin heavy chain chr11 Not Cancer Driver No 2 hippie, biogrid 18 57 7 7 0
GABPA-202 GABPA Q06546 GA-binding protein alpha chain chr21 Not Cancer Driver No 1 hippie, biogrid 49 104 7 7 0
GID8-201 GID8 Q9NWU2 Glucose-induced degradation protein 8 homolog chr20 Not Cancer Driver No 2 intact, hippie 23 60 5 5 0
GMCL1-201 GMCL1 Q96IK5 Germ cell-less protein-like 1 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 23 80 2 2 0
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
GUCY1A1-205 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 Not Cancer Driver No 1 hippie 147 54 8 8 0
H4C1-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 6 32 0 0 11
H4C11-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 18 31 2 2 11
H4C12-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 27 32 1 1 11
H4C13-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 17 31 4 4 11
H4C14-201 H4C16 P62805 Histone H4 chr1 Not Cancer Driver No 1 intact 0 31 0 0 11
H4C15-201 H4C16 P62805 Histone H4 chr1 Not Cancer Driver No 1 intact 0 31 0 0 11
H4C16-204 H4C16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 15 31 2 2 12
H4C2-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 32 3 3 11
H4C3-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 24 31 2 2 11
H4C4-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 1 1 11
H4C5-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 4 4 11
H4C6-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 18 31 1 1 11
H4C8-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 13 32 2 2 11
H4C9-201 H4C16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 4 4 11
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 hippie, biogrid 378 366 163 163 15
HDAC9-212 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie, biogrid 222 631 140 140 0
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 33 290 22 22 4
HSF2-201 HSF2 Q03933 Heat shock factor protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 42 292 25 25 0
ITGA9-201 ITGA9 Q13797 Integrin alpha-9 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 93 70 5 5 0
IVL-201 IVL P07476 Involucrin chr1 Not Cancer Driver No 1 hippie 28 589 28 28 0
JADE1-201 JADE1 Q6IE81 Protein Jade-1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 74 410 34 34 0
KAT7-201 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie, biogrid 64 327 27 27 0
KLHL11-201 KLHL11 Q9NVR0 Kelch-like protein 11 chr17 Not Cancer Driver No 1 hippie, biogrid 56 85 6 6 0
KRT1-201 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 1 hippie 68 429 40 40 15
L2HGDH-202 L2HGDH Q9H9P8 L-2-hydroxyglutarate dehydrogenase, mitochondrial chr14 Not Cancer Driver No 3 intact, hippie, biogrid 33 0 0 0 7
LACC1-201 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 1 intact, hippie 40 4 0 0 1
LIAS-222 LIAS O43766 Lipoyl synthase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 32 83 8 8 1
LRRC10-201 LRRC10 Q5BKY1 Leucine-rich repeat-containing protein 10 chr12 Not Cancer Driver No 1 hippie, biogrid 42 38 8 8 0
LY86-201 LY86 O95711 Lymphocyte antigen 86 chr6 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
MBD4-201 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 34 268 11 11 1
MBNL1-201 MBNL1 Q9NR56 Muscleblind-like protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 154 14 14 0
MPI-202 MPI P34949 Mannose-6-phosphate isomerase chr15 Not Cancer Driver No 2 hippie, biogrid 26 61 8 8 13
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
NPPA-202 NPPA P01160 Natriuretic peptides A chr1 Not Cancer Driver No 2 intact, hippie, biogrid 21 72 13 13 1
NRSN1-204 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 41 18 6 6 0
NT5C1A-201 NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 Not Cancer Driver No 1 hippie, biogrid 64 95 9 9 0
NUDT3-201 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 16 38 5 5 0
OR13C3-201 OR13C3 Q8NGS6 Olfactory receptor 13C3 chr9 Not Cancer Driver No 1 hippie, biogrid 75 0 0 0 0
OR2A4-201 OR2A4 O95047 Olfactory receptor 2A4 chr6 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
P2RX6-202 P2RX6 O15547 P2X purinoceptor 6 chr22 Not Cancer Driver No 1 hippie, biogrid 22 43 1 1 0
PCP4-201 PCP4 P48539 Calmodulin regulator protein PCP4 chr21 Not Cancer Driver No 1 hippie, biogrid 14 62 14 14 0
PDE4DIP-205 PDE4DIP Q5VU43 Myomegalin chr1 Census, Compendium Yes 2 intact, hippie, biogrid 380 1640 276 276 0
PHF11-202 PHF11 Q9UIL8 PHD finger protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 22 82 9 9 0
PHF8-204 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 hippie, biogrid 104 603 58 58 1
PI4KA-201 PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 198 142 10 10 7
PIGT-202 PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 42 36 6 6 1
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 46 99 8 8 24
PKP1-202 PKP1 Q13835 Plakophilin-1 chr1 Not Cancer Driver No 1 hippie, biogrid 82 192 20 20 0
POF1B-201 POF1B Q8WVV4 Protein POF1B chrX Not Cancer Driver No 1 hippie, biogrid 121 386 82 82 1
POT1-201 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 98 31 5 5 9
POU3F3-201 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 Not Cancer Driver No 1 hippie, biogrid 39 404 27 27 3
PPP2R2B-203 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie, biogrid 66 76 11 11 1
PRMT5-202 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact 62 72 3 3 0
PRXL2A-205 PRXL2A Q9BRX8 Peroxiredoxin-like 2A chr10 Not Cancer Driver No 1 hippie 24 0 0 0 0
PTDSS1-202 PTDSS1 P48651 Phosphatidylserine synthase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 56 44 4 4 3
RANBP3-202 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 52 470 42 42 0
RBM24-202 RBM24 Q9BX46 RNA-binding protein 24 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 24 20 3 3 0
RHBDD1-202 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 29 69 8 8 0
RIPPLY3-201 RIPPLY3 P57055 Protein ripply3 chr21 Not Cancer Driver No 1 hippie, biogrid 42 192 42 42 0
RNF115-202 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 Not Cancer Driver No 1 hippie, biogrid 23 136 11 11 0
RNF25-201 RNF25 Q96BH1 E3 ubiquitin-protein ligase RNF25 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 45 289 34 34 0
SARAF-201 SARAF Q96BY9 Store-operated calcium entry-associated regulatory factor chr8 Not Cancer Driver No 1 hippie, biogrid 23 75 8 8 0
SERPINB3-201 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie, biogrid 116 47 23 23 0
SERPINB5-201 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie, biogrid 42 50 4 4 0
SFN-201 SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie, biogrid 16 75 3 3 0
SH2D3A-201 SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 52 308 30 30 0
SINHCAF-201 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 Not Cancer Driver No 1 intact, hippie 16 108 10 10 0
SLC25A6-201 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
SLC35F2-204 SLC35F2 Q8IXU6 Solute carrier family 35 member F2 chr11 Not Cancer Driver No 1 hippie, biogrid 37 12 0 0 0
SLC37A4-201 SLC37A4 O43826 Glucose-6-phosphate exchanger SLC37A4 chr11 Not Cancer Driver No 1 hippie, biogrid 26 17 1 1 28
SPRR3-201 SPRR3 Q9UBC9 Small proline-rich protein 3 chr1 Not Cancer Driver No 1 hippie 36 171 36 36 0
SRRT-213 SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 Not Cancer Driver No 1 hippie, biogrid 96 596 68 68 0
SSBP2-201 SSBP2 P81877 Single-stranded DNA-binding protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 25 296 22 22 0
SSUH2-216 SSUH2 Q9Y2M2 Protein SSUH2 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 46 77 6 6 1
ST6GALNAC6-205 ST6GALNAC6 Q969X2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 chr9 Not Cancer Driver No 1 hippie, biogrid 29 87 7 7 0
ST7-201 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie, biogrid 37 64 6 6 0
STK11-201 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 hippie, biogrid 63 135 12 12 9
STX17-201 STX17 P56962 Syntaxin-17 chr9 Not Cancer Driver No 1 hippie, biogrid 24 81 6 6 0
SUSD3-202 SUSD3 Q96L08 Sushi domain-containing protein 3 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 29 124 12 12 0
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 intact, hippie 37 302 25 25 0
TBC1D22B-201 TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 2 intact, hippie, biogrid 43 206 23 23 0
TEFM-205 TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 19 26 3 3 0
TSPAN6-201 TSPAN6 O43657 Tetraspanin-6 chrX Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
UCHL5-206 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 Not Cancer Driver No 1 hippie 23 41 2 2 0
UGT1A10-201 UGT1A10 Q9HAW8 UDP-glucuronosyltransferase 1A10 chr2 Not Cancer Driver No 3 hippie, biogrid 92 11 0 0 0
UPK1A-201 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 intact 25 42 2 2 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
ZC3HC1-202 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 44 252 19 19 0
ZDHHC19-201 ZDHHC19 Q8WVZ1 Palmitoyltransferase ZDHHC19 chr3 Not Cancer Driver No 1 hippie, biogrid 40 35 9 9 0
ZDHHC6-202 ZDHHC6 Q9H6R6 Palmitoyltransferase ZDHHC6 chr10 Not Cancer Driver No 1 hippie, biogrid 38 11 3 3 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0
ZIC1-201 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 172 246 102 102 1
ZNF550-208 ZNF550 Q7Z398 Zinc finger protein 550 chr19 Not Cancer Driver No 1 hippie, biogrid 31 109 9 9 0
ZSCAN12-203 ZSCAN12 O43309 Zinc finger and SCAN domain-containing protein 12 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 33 262 19 19 0
ZSCAN20-204 ZSCAN20 P17040 Zinc finger and SCAN domain-containing protein 20 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 128 538 63 63 0