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KIF2C-202 ,KIF2C ,Q99661
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 126
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR3B-201 ACTR3B Q9P1U1 Actin-related protein 3B chr7 Not Cancer Driver No 1 hippie, biogrid 41 5 0 0 0
ADAM9-209 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie 59 130 7 7 0
ANAPC4-201 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 Not Cancer Driver No 1 hippie 48 54 0 0 0
ANKS3-201 ANKS3 Q6ZW76 Ankyrin repeat and SAM domain-containing protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 50 293 20 20 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 37 154 11 11 0
ATP6V0C-201 ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 25 180 17 17 0
AURKB-214 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 31 63 4 4 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BCCIP-201 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 1 hippie 23 99 13 13 0
BMP1-202 BMP1 P13497 Bone morphogenetic protein 1 chr8 Not Cancer Driver No 2 hippie, biogrid 93 154 23 23 3
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BRPF1-215 BRPF1 P55201 Peregrin chr3 Not Cancer Driver No 1 hippie 108 754 68 68 2
CALML3-201 CALML3 P27482 Calmodulin-like protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 27 106 26 26 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 60 621 46 46 0
CDCA8-202 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 hippie 18 171 10 10 0
CENPB-201 CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 1 hippie 33 374 16 16 0
CENPH-201 CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie 20 85 6 6 0
CEP170-202 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 Not Cancer Driver No 1 hippie 181 1432 171 171 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CSNK2B-203 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 18 19 0 0 3
DCTN1-226 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 hippie, biogrid 129 818 84 84 9
DDHD1-210 DDHD1 Q8NEL9 Phospholipase DDHD1 chr14 Not Cancer Driver No 1 hippie, biogrid 88 395 33 33 0
DHFR2-201 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 13 20 0 0 0
DNM3-201 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 3 hippie, biogrid 112 257 21 21 0
DUSP3-201 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ELAC2-201 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 69 208 25 25 10
ESPL1-201 ESPL1 Q14674 Separin chr12 Not Cancer Driver No 1 hippie 172 383 27 27 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FADD-201 FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 24 45 9 9 1
FBXO11-202 FBXO11 Q86XK2 F-box only protein 11 chr2 Census, Compendium Yes 1 hippie, biogrid 85 242 17 17 8
FBXO5-201 FBXO5 Q9UKT4 F-box only protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 29 114 10 10 0
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 289 1249 137 137 8
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
GTF2F1-201 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 Not Cancer Driver No 1 hippie 47 427 35 35 0
HABP4-201 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 21 415 21 21 0
HAX1-201 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 219 23 23 2
HORMAD2-201 HORMAD2 Q8N7B1 HORMA domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 18 29 1 1 0
HSPA14-201 HSPA14 Q0VDF9 Heat shock 70 kDa protein 14 chr10 Not Cancer Driver No 1 hippie, biogrid 34 22 0 0 0
INSYN1-203 INSYN1 Q2T9L4 Inhibitory synaptic factor 1 chr15 Not Cancer Driver No 1 hippie 35 256 34 34 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF18B-204 KIF18B Q86Y91 Kinesin-like protein KIF18B chr17 Not Cancer Driver No 1 hippie 74 592 51 51 0
KIF2A-202 KIF2A O00139 Kinesin-like protein KIF2A chr5 Not Cancer Driver No 2 hippie, biogrid 47 336 22 22 2
KIF2B-201 KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 276 189 99 99 0
KIF2C-202 KIF2C Q99661 Kinesin-like protein KIF2C chr1 Not Cancer Driver No 1 hippie 82 338 48 48 0
KLHL40-201 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 82 44 6 6 13
KRT38-201 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie, biogrid 70 54 16 16 0
KRT79-201 KRT79 Q5XKE5 Keratin, type II cytoskeletal 79 chr12 Not Cancer Driver No 1 hippie 71 232 35 35 0
KXD1-201 KXD1 Q9BQD3 KxDL motif-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 17 105 12 12 0
LSM14A-201 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie, biogrid 51 408 47 47 0
MAPRE1-201 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 17 109 5 5 0
MAPRE3-201 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 2 hippie, biogrid 24 120 11 11 0
MBD1-201 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 1 hippie 77 323 30 30 0
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 8 46 2 2 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MRFAP1L1-201 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 8 59 4 4 0
MRPL52-202 MRPL52 Q86TS9 Large ribosomal subunit protein mL52 chr14 Not Cancer Driver No 1 hippie 7 75 5 5 0
MTREX-201 MTREX P42285 Exosome RNA helicase MTR4 chr5 Not Cancer Driver No 1 hippie 85 160 11 11 0
MTUS2-206 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 308 1216 290 290 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYO18A-203 MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie, biogrid 181 1246 112 112 0
NDEL1-201 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 Not Cancer Driver No 1 hippie 23 203 13 13 0
NFATC2-202 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 144 726 124 124 0
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NTAQ1-201 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 24 27 3 3 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
PAPLN-212 PAPLN O95428 Papilin chr14 Not Cancer Driver No 2 intact, hippie, biogrid 116 578 52 52 0
PAXIP1-201 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 41 462 1 1 0
PCBP2-204 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 28 200 15 15 0
PCGF5-201 PCGF5 Q86SE9 Polycomb group RING finger protein 5 chr10 Not Cancer Driver No 1 hippie 23 52 3 3 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
POP1-202 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 Not Cancer Driver No 1 hippie 122 497 61 61 3
PRPF38B-203 PRPF38B Q5VTL8 Pre-mRNA-splicing factor 38B chr1 Not Cancer Driver No 1 hippie, biogrid 21 387 6 6 0
PRRC2A-202 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie, biogrid 111 2119 107 107 0
PTPN3-202 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 Not Cancer Driver No 1 hippie 105 214 24 24 0
RBM26-203 RBM26 Q5T8P6 RNA-binding protein 26 chr13 Not Cancer Driver No 1 hippie, biogrid 68 835 64 64 0
RBMX2-201 RBMX2 Q9Y388 RNA-binding motif protein, X-linked 2 chrX Not Cancer Driver No 1 hippie, biogrid 24 217 18 18 0
RBMXL1-204 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 Not Cancer Driver No 1 hippie, biogrid 47 372 47 47 0
RBPJ-206 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 32 151 10 10 2
RELL2-201 RELL2 Q8NC24 RELT-like protein 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 30 260 29 29 0
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RPL5-202 RPL5 P46777 Large ribosomal subunit protein uL18 chr1 Census Yes 1 hippie 39 96 10 10 2
RPL7-201 RPL7 P18124 Large ribosomal subunit protein uL30 chr8 Not Cancer Driver No 1 hippie 11 40 0 0 0
RPS25-202 RPS25 P62851 Small ribosomal subunit protein eS25 chr11 Not Cancer Driver No 1 hippie 12 60 7 7 0
RRP12-202 RRP12 Q5JTH9 RRP12-like protein chr10 Not Cancer Driver No 1 hippie 127 340 49 49 0
RRP36-201 RRP36 Q96EU6 Ribosomal RNA processing protein 36 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 18 219 16 16 0
SAR1B-201 SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 Not Cancer Driver No 1 hippie, biogrid 13 4 0 0 5
SDF4-202 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie 38 195 27 27 0
SEMG1-201 SEMG1 P04279 Semenogelin-1 chr20 Not Cancer Driver No 1 hippie, biogrid 80 448 79 79 0
SEMG2-201 SEMG2 Q02383 Semenogelin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 121 567 120 120 0
SGF29-201 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 2 intact, hippie 25 132 12 12 0
SGMS2-210 SGMS2 Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 chr4 Not Cancer Driver No 1 hippie 20 49 4 4 0
SGO1-201 SGO1 Q5FBB7 Shugoshin 1 chr3 Not Cancer Driver No 1 hippie 45 361 29 29 1
SGO2-201 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 hippie 111 1029 91 91 0
SMC4-202 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 136 539 40 40 0
SNRNP27-201 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 1 hippie, biogrid 5 155 5 5 0
SNW1-201 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 59 487 53 53 0
SRGAP3-202 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie 166 551 87 87 0
STK3-201 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie, biogrid 48 241 22 22 0
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie, biogrid 49 233 20 20 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 37 302 25 25 0
TBC1D7-204 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 Not Cancer Driver No 1 hippie 30 1 0 0 0
TCP10L-201 TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 23 216 23 23 0
TEX10-201 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 hippie 74 103 10 10 0
TJP1-201 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie, biogrid 143 1350 113 113 0
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 2 intact, hippie, biogrid 38 111 14 14 9
TNFRSF1B-201 TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 hippie, biogrid 40 231 21 21 0
TRIM36-201 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 hippie, biogrid 81 89 15 15 1
TYW3-201 TYW3 Q6IPR3 tRNA wybutosine-synthesizing protein 3 homolog chr1 Not Cancer Driver No 2 intact, hippie, biogrid 27 57 8 8 0
UBE2A-202 UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie, biogrid 23 67 11 11 2
UTP11-201 UTP11 Q9Y3A2 Probable U3 small nucleolar RNA-associated protein 11 chr1 Not Cancer Driver No 1 hippie 21 104 5 5 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 hippie 152 110 21 21 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 85 117 15 15 84
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WDR18-202 WDR18 Q9BV38 WD repeat-containing protein 18 chr19 Not Cancer Driver No 1 hippie 31 60 3 3 0
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WDR62-201 WDR62 O43379 WD repeat-containing protein 62 chr19 Not Cancer Driver No 1 hippie 136 801 71 71 5
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
ZNF566-205 ZNF566 Q969W8 Zinc finger protein 566 chr19 Not Cancer Driver No 1 hippie 59 53 7 7 0
ZNF668-201 ZNF668 Q96K58 Zinc finger protein 668 chr16 Not Cancer Driver No 1 hippie 71 313 35 35 0