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LEPR-202 ,LEPR ,P48357
  • Number of Interaction partner in intact: 6
  • Number of Interaction partner in biogrid: 12
  • Number of Interaction partner in hippie: 39
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGO4-201 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 1 hippie, biogrid 83 183 22 22 0
ANKLE2-201 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 105 524 62 62 2
APOD-201 APOD P05090 Apolipoprotein D chr3 Not Cancer Driver No 1 hippie 23 13 1 1 0
AS3MT-201 AS3MT Q9HBK9 Arsenite methyltransferase chr10 Not Cancer Driver No 1 hippie, biogrid 22 5 0 0 0
ATP6V0D1-201 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
BTNL8-202 BTNL8 Q6UX41 Butyrophilin-like protein 8 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 99 86 17 17 0
CDCP1-201 CDCP1 Q9H5V8 CUB domain-containing protein 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 93 161 22 22 0
CLU-201 CLU P10909 Clusterin chr8 Not Cancer Driver No 1 hippie 43 157 18 18 0
CSNK2B-203 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 18 19 0 0 3
DGKZ-205 DGKZ Q13574 Diacylglycerol kinase zeta chr11 Not Cancer Driver No 1 hippie 65 411 30 30 0
FBXO2-201 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 76 0 0 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
GHSR-201 GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 Not Cancer Driver No 1 hippie 60 4 0 0 2
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 21 10 0 0 0
HCRTR1-203 HCRTR1 O43613 Orexin/Hypocretin receptor type 1 chr1 Not Cancer Driver No 1 hippie 40 28 0 0 0
JAK2-201 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 81 59 4 4 4
JAK3-201 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 131 63 4 4 7
LEP-201 LEP P41159 Leptin chr7 Not Cancer Driver No 2 hippie, biogrid 20 0 0 0 2
LEPR-202 LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 2 intact, hippie 178 57 10 10 0
LEPROT-201 LEPROT O15243 Leptin receptor gene-related protein chr1 Not Cancer Driver No 1 hippie 12 0 0 0 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 hippie 119 117 40 40 0
PIN1-201 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie, biogrid 13 116 11 11 0
PTPN11-201 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 92 260 27 27 44
PTPRC-209 PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 hippie 257 462 91 91 0
PTPRJ-201 PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 Not Cancer Driver No 1 hippie 130 403 39 39 0
RNF41-201 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie 36 33 2 2 0
SCGB1D1-201 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 15 0 0 0 0
SERPINI2-201 SERPINI2 O75830 Serpin I2 chr3 Not Cancer Driver No 1 hippie, biogrid 87 22 9 9 0
SLURP1-201 SLURP1 P55000 Secreted Ly-6/uPAR-related protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 8
SNX1-208 SNX1 Q13596 Sorting nexin-1 chr15 Not Cancer Driver No 1 hippie 46 216 17 17 0
SNX2-201 SNX2 O60749 Sorting nexin-2 chr5 Not Cancer Driver No 1 hippie 34 218 9 9 0
SNX4-201 SNX4 O95219 Sorting nexin-4 chr3 Not Cancer Driver No 1 hippie 19 101 4 4 0
SNX6-201 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie 22 86 4 4 0
SOCS3-201 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 24 111 11 11 0
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 93 152 16 16 15
TAFA2-201 TAFA2 Q8N3H0 Chemokine-like protein TAFA-2 chr12 Not Cancer Driver No 1 hippie 43 4 1 1 0
TAFA4-201 TAFA4 Q96LR4 Chemokine-like protein TAFA-4 chr3 Not Cancer Driver No 1 intact, hippie 30 4 0 0 0
UBC-201 UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 intact 80 320 42 42 0
USP8-201 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 1 hippie 82 603 49 49 0
XRN1-201 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 hippie 167 578 50 50 0