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LHX8-201 ,LHX8 ,Q68G74
  • Number of Interaction partner in intact: 40
  • Number of Interaction partner in biogrid: 3
  • Number of Interaction partner in hippie: 61
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2-203 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 intact, hippie 46 377 30 30 0
ARID2-201 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 Census, Compendium Yes 1 hippie 205 1144 111 111 0
ATF2-201 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 42 451 36 36 0
ATF6B-210 ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 Not Cancer Driver No 1 intact, hippie 58 557 46 46 0
AXIN1-201 AXIN1 O15169 Axin-1 chr16 Census, Compendium Yes 1 intact, hippie 91 623 69 69 4
BANP-201 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 intact, hippie 44 315 27 27 0
BCL9-201 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 Census, Compendium Yes 1 hippie 164 1431 164 164 0
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
CCHCR1-201 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie 70 565 57 57 0
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 intact, hippie 65 72 8 8 1
CRK-201 CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 24 197 19 19 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 intact, hippie 47 75 6 6 4
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 intact 61 378 23 23 0
DPF1-201 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 Not Cancer Driver No 1 hippie 27 85 7 7 0
ECH1-201 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 28 23 2 2 0
EFS-201 EFS O43281 Embryonal Fyn-associated substrate chr14 Not Cancer Driver No 1 hippie 52 416 36 36 0
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 134 241 18 18 32
FIGLA-201 FIGLA Q6QHK4 Factor in the germline alpha chr2 Not Cancer Driver No 2 intact, hippie, biogrid 20 155 15 15 0
FOSL2-201 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 1 intact, hippie 39 323 39 39 0
FOXN1-203 FOXN1 O15353 Forkhead box protein N1 chr17 Not Cancer Driver No 1 intact, hippie 83 485 62 62 2
GINS4-201 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 Not Cancer Driver No 1 hippie 25 77 10 10 0
GLE1-201 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 intact, hippie 49 300 25 25 3
GRIN2C-201 GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 78 278 3 3 0
GRN-201 GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 64 29 4 4 1
GRPEL1-201 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie 13 88 5 5 0
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
ISL2-201 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 Not Cancer Driver No 1 intact, hippie 20 168 10 10 0
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 187 634 82 82 1
KLF3-201 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 2 intact, hippie 43 243 31 31 0
KMT2D-201 KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 intact, hippie 313 4394 276 276 18
KRT85-201 KRT85 P78386 Keratin, type II cuticular Hb5 chr12 Not Cancer Driver No 1 hippie 78 29 2 2 1
LDB1-204 LDB1 Q86U70 LIM domain-binding protein 1 chr10 Compendium Yes 2 intact, hippie 49 178 26 26 0
LDB2-201 LDB2 O43679 LIM domain-binding protein 2 chr4 Not Cancer Driver No 1 intact, hippie 99 145 42 42 0
LHX6-203 LHX6 Q9UPM6 LIM/homeobox protein Lhx6 chr9 Not Cancer Driver No 1 intact, hippie 27 134 6 6 0
LMO4-202 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 29 11 1 1 0
MBD2-201 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 intact 10 384 10 10 0
NEDD9-202 NEDD9 Q14511 Enhancer of filamentation 1 chr6 Not Cancer Driver No 1 intact, hippie 80 520 55 55 0
NUTM1-201 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 intact, hippie 156 975 137 137 0
PBRM1-201 PBRM1 Q86U86 Protein polybromo-1 chr3 Census, Compendium Yes 1 hippie 162 704 61 61 0
PCGF1-201 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 1 hippie 22 8 1 1 0
PEX1-201 PEX1 O43933 Peroxisomal ATPase PEX1 chr7 Not Cancer Driver No 1 hippie 98 304 22 22 17
PHB1-201 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 21 4 1 1 0
PHF10-201 PHF10 Q8WUB8 PHD finger protein 10 chr6 Not Cancer Driver No 1 hippie 27 298 21 21 0
PLCG2-206 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 183 144 18 18 1
PRPF31-201 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 37 213 9 9 2
PYGO1-201 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 40 364 36 36 0
PYGO2-202 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 Not Cancer Driver No 1 intact, hippie 44 341 39 39 0
RNF11-201 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 11 78 6 6 0
SCYL3-203 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 intact, hippie 56 250 18 18 0
SMARCA2-203 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 178 1015 100 100 36
SMARCD2-203 SMARCD2 Q92925 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 chr17 Not Cancer Driver No 1 hippie 42 251 15 15 0
SPRED1-201 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 53 195 28 28 2
SSBP2-201 SSBP2 P81877 Single-stranded DNA-binding protein 2 chr5 Not Cancer Driver No 1 hippie 25 296 22 22 0
SSBP3-216 SSBP3 Q9BWW4 Single-stranded DNA-binding protein 3 chr1 Not Cancer Driver No 1 intact, hippie 31 321 23 23 0
SSBP4-201 SSBP4 Q9BWG4 Single-stranded DNA-binding protein 4 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 29 318 20 20 0
SUV39H1-202 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 intact, hippie 43 15 1 1 0
TBC1D1-201 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 Not Cancer Driver No 1 intact, hippie 90 459 36 36 0
TBC1D22B-201 TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 1 intact, hippie 43 206 23 23 0
TFAM-204 TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie 19 110 11 11 1
TLE1-203 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 intact, hippie 86 385 39 39 0
TSC1-201 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 intact 94 735 53 53 11
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 40 545 38 38 0
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40
ZBTB24-201 ZBTB24 O43167 Zinc finger and BTB domain-containing protein 24 chr6 Not Cancer Driver No 1 hippie 48 384 31 31 1
ZNF609-201 ZNF609 O15014 Zinc finger protein 609 chr15 Not Cancer Driver No 1 intact, hippie 107 1338 100 100 0