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LYPLAL1-202 ,LYPLAL1 ,Q5VWZ2
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 35
  • Number of Interaction partner in hippie: 53
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2-201 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 91 203 23 23 5
AK1-206 AK1 P00568 Adenylate kinase isoenzyme 1 chr9 Not Cancer Driver No 1 hippie, biogrid 13 55 1 1 4
ALDH4A1-202 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 48 47 8 8 1
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 20 192 18 18 0
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 5 5 2
CCDC90B-214 CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 23 77 4 4 0
CD300E-201 CD300E Q496F6 CMRF35-like molecule 2 chr17 Not Cancer Driver No 1 hippie, biogrid 34 38 10 10 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 38 13 2 2 0
CT55-201 CT55 Q8WUE5 Cancer/testis antigen 55 chrX Not Cancer Driver No 1 intact, hippie 30 40 2 2 0
CTDSP1-201 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 30 46 1 1 0
DSTN-201 DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie, biogrid 9 0 0 0 0
ENG-202 ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 47 114 11 11 29
FABP3-201 FABP3 P05413 Fatty acid-binding protein, heart chr1 Not Cancer Driver No 1 hippie, biogrid 13 3 0 0 0
GFM1-210 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 49 79 5 5 4
GRSF1-201 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie 33 147 15 15 0
HINT1-201 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 7 6 0 0 7
HINT2-201 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 6 29 1 1 0
HMGCL-203 HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 8 2 2 17
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 45 83 1 1 2
IDH2-201 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 51 61 0 0 4
INHBA-201 INHBA P08476 Inhibin beta A chain chr7 Not Cancer Driver No 1 hippie, biogrid 121 154 54 54 0
LONP1-201 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 75 178 16 16 10
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 99 18 0 0 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 4 17 0 0 0
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MSRB2-201 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 11 66 6 6 0
MTIF2-201 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 114 7 7 0
NBR1-206 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie 88 562 41 41 0
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 32 49 7 7 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 36 22 2 2 4
PRTN3-201 PRTN3 P24158 Myeloblastin chr19 Not Cancer Driver No 1 hippie, biogrid 17 46 1 1 0
PTRHD1-201 PTRHD1 Q6GMV3 Putative peptidyl-tRNA hydrolase PTRHD1 chr2 Not Cancer Driver No 1 hippie, biogrid 10 22 2 2 0
RAMP3-201 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
SCLT1-201 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 72 401 49 49 0
SH3BGRL-201 SH3BGRL O75368 Adapter SH3BGRL chrX Not Cancer Driver No 1 hippie, biogrid 17 51 7 7 0
SH3BGRL3-201 SH3BGRL3 Q9H299 SH3 domain-binding glutamic acid-rich-like protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 7 34 3 3 0
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 6
SUMF2-208 SUMF2 Q8NBJ7 Inactive C-alpha-formylglycine-generating enzyme 2 chr7 Not Cancer Driver No 1 hippie, biogrid 23 105 8 8 0
TAX1BP1-202 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 43 429 29 29 0
TBRG4-201 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 56 61 1 1 0
TRAP1-201 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 110 6 6 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 40 124 11 11 0
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
TST-201 TST Q16762 Thiosulfate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 22 56 5 5 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0