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MARK1-201 ,MARK1 ,Q9P0L2
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 39
  • Number of Interaction partner in hippie: 52
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 biogrid 94 87 10 10 1
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 biogrid 91 142 12 12 10
AGO3-203 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 biogrid 93 143 18 18 0
AGO4-201 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 1 biogrid 83 183 22 22 0
APBA1-201 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 117 558 78 78 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 94 419 52 52 12
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
CCDC102B-201 CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie 98 337 71 71 0
CDH19-201 CDH19 Q9H159 Cadherin-19 chr18 Not Cancer Driver No 2 hippie, biogrid 157 176 35 35 0
CEP85L-203 CEP85L Q5SZL2 Centrosomal protein of 85 kDa-like chr6 Not Cancer Driver No 1 hippie, biogrid 66 549 51 51 2
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
DAPK1-202 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 149 116 12 12 0
DDX60L-216 DDX60L Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like chr4 Not Cancer Driver No 1 biogrid 165 85 7 7 0
DHRS12-211 DHRS12 A0PJE2 Dehydrogenase/reductase SDR family member 12 chr13 Not Cancer Driver No 1 biogrid 19 102 10 10 0
DTNA-205 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 biogrid 107 412 58 58 0
DTNB-208 DTNB O60941 Dystrobrevin beta chr2 Not Cancer Driver No 1 biogrid 58 339 35 35 0
DYNLT1-203 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
FUCA1-201 FUCA1 P04066 Tissue alpha-L-fucosidase chr1 Not Cancer Driver No 1 biogrid 30 13 1 1 3
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GJA5-202 GJA5 P36382 Gap junction alpha-5 protein chr1 Not Cancer Driver No 1 hippie 52 92 12 12 5
GPSM3-206 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 Not Cancer Driver No 1 hippie, biogrid 14 160 14 14 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
INCA1-205 INCA1 Q0VD86 Protein INCA1 chr17 Not Cancer Driver No 1 intact, hippie 14 196 11 11 0
KCNJ2-201 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 85 49 7 7 12
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 771 7 2 2 22
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie 122 790 74 74 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MAP2-218 MAP2 P11137 Microtubule-associated protein 2 chr2 Compendium Yes 1 hippie 294 1734 277 277 0
MAP4-202 MAP4 P27816 Microtubule-associated protein 4 chr3 Not Cancer Driver No 1 hippie 83 1140 80 80 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 2 intact, hippie 100 750 99 99 17
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MARK1-201 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 Not Cancer Driver No 1 hippie 129 454 81 81 0
MARK2-204 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 84 445 52 52 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 biogrid 64 376 38 38 1
MST1-202 MST1 P26927 Hepatocyte growth factor-like protein chr3 Not Cancer Driver No 1 hippie 57 171 9 9 0
NEK4-201 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 55 495 40 40 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 272 10 0 0 12
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PNMA2-204 PNMA2 Q9UL42 Paraneoplastic antigen Ma2 chr8 Not Cancer Driver No 1 hippie, biogrid 36 45 2 2 0
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 19 23 3 3 0
PPP6R2-201 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 Not Cancer Driver No 1 biogrid 76 496 48 48 0
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 54 124 13 13 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
SCRIB-201 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 intact, hippie 169 1071 117 117 2
SF3A2-201 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 intact, hippie 15 384 10 10 0
SFN-201 SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 2 hippie, biogrid 16 75 3 3 0
SH3PXD2A-203 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 biogrid 111 802 86 86 0
SNTB1-202 SNTB1 Q13884 Beta-1-syntrophin chr8 Not Cancer Driver No 1 biogrid 59 190 17 17 0
SNTB2-201 SNTB2 Q13425 Beta-2-syntrophin chr16 Not Cancer Driver No 1 biogrid 17 163 1 1 0
STIM1-201 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 biogrid 55 386 35 35 12
STK11-201 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 2 intact, hippie 63 135 12 12 9
TAOK1-201 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 Not Cancer Driver No 1 hippie 94 602 48 48 7
TCL1B-201 TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 Not Cancer Driver No 1 hippie 31 11 1 1 0
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TPX2-201 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 Not Cancer Driver No 1 biogrid 66 700 61 61 0
TRIM11-201 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 Not Cancer Driver No 1 hippie 46 132 16 16 0
USP21-203 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 86 230 44 44 0
UTRN-204 UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 biogrid 352 1287 137 137 0
YAF2-203 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 intact, hippie 22 169 22 22 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 4 intact, hippie, biogrid 19 110 3 3 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 2 intact, hippie, biogrid 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 4 intact, hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 4 intact, hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 5 intact, hippie, biogrid 19 81 7 7 0