Filter in search result
MCL1-202 ,MCL1 ,Q07820
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 47
  • Number of Interaction partner in hippie: 116
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 96 43 5 5 4
ADAM32-201 ADAM32 Q8TC27 Disintegrin and metalloproteinase domain-containing protein 32 chr8 Not Cancer Driver No 1 hippie, biogrid 92 88 10 10 0
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 hippie 91 142 12 12 10
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 23 104 9 9 0
ARG1-203 ARG1 P05089 Arginase-1 chr6 Not Cancer Driver No 1 hippie, biogrid 27 83 8 8 9
ATG12-208 ATG12 O94817 Ubiquitin-like protein ATG12 chr5 Not Cancer Driver No 1 hippie 13 61 6 6 0
ATG2A-201 ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 hippie 175 891 104 104 0
ATPAF1-211 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 hippie 24 47 4 4 0
BAD-201 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 10 165 10 10 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BAG4-201 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 hippie 40 402 36 36 0
BAG6-237 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie, biogrid 73 856 59 59 0
BAK1-201 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 Not Cancer Driver No 4 hippie, biogrid 25 58 5 5 0
BAX-202 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 4 hippie, biogrid 24 39 2 2 0
BBC3-204 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 Not Cancer Driver No 4 hippie, biogrid 16 253 16 16 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 1 hippie 21 73 5 5 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 3 hippie, biogrid 22 55 2 2 0
BCL2L11-204 BCL2L11 O43521 Bcl-2-like protein 11 chr2 Not Cancer Driver No 4 hippie, biogrid 37 131 16 16 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 36 190 15 15 0
BID-211 BID P55957 BH3-interacting domain death agonist chr22 Not Cancer Driver No 2 hippie, biogrid 17 75 5 5 0
BIK-201 BIK Q13323 Bcl-2-interacting killer chr22 Not Cancer Driver No 1 hippie 10 21 3 3 0
BMF-201 BMF Q96LC9 Bcl-2-modifying factor chr15 Not Cancer Driver No 1 hippie 16 94 7 7 0
BOK-201 BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 Not Cancer Driver No 1 hippie 5 0 0 0 0
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 57 45 3 3 0
C5AR2-201 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 Not Cancer Driver No 2 hippie, biogrid 41 11 1 1 0
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie 28 245 16 16 0
CASP3-201 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 19 64 1 1 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 23 2 0 0 0
CDC20-201 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 36 198 12 12 0
CHRM4-202 CHRM4 P08173 Muscarinic acetylcholine receptor M4 chr11 Not Cancer Driver No 1 hippie 57 143 21 21 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie 13 5 1 1 1
CPT2-201 CPT2 P23786 Carnitine O-palmitoyltransferase 2, mitochondrial chr1 Not Cancer Driver No 2 hippie, biogrid 39 71 4 4 21
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 127 65 9 9 0
DAD1-201 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 Not Cancer Driver No 1 hippie 6 0 0 0 0
DBI-202 DBI P07108 Acyl-CoA-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 10 27 6 6 0
DOT1L-201 DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 Compendium Yes 1 biogrid 135 990 81 81 0
DUSP22-201 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 hippie 76 0 0 0 0
DYNLL1-201 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
DYNLL2-201 DYNLL2 Q96FJ2 Dynein light chain 2, cytoplasmic chr17 Not Cancer Driver No 1 hippie, biogrid 5 0 0 0 0
ECM1-202 ECM1 Q16610 Extracellular matrix protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 66 224 23 23 1
EDEM1-201 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 44 141 5 5 0
EDEM2-202 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 Not Cancer Driver No 2 hippie, biogrid 54 55 3 3 0
EDNRA-209 EDNRA P25101 Endothelin-1 receptor chr4 Not Cancer Driver No 3 hippie, biogrid 52 21 5 5 2
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 249 315 32 32 1
FBXO4-201 FBXO4 Q9UKT5 F-box only protein 4 chr5 Not Cancer Driver No 1 hippie 38 68 6 6 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 289 232 15 15 17
FLG-201 FLG P20930 Filaggrin chr1 Not Cancer Driver No 2 hippie, biogrid 1351 4059 1373 1373 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 36 24 3 3 0
GBP5-201 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 80 170 18 18 0
GSK3A-201 GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 33 180 5 5 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 34 148 6 6 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie, biogrid 129 16 2 2 10
HRK-201 HRK O00198 Activator of apoptosis harakiri chr12 Not Cancer Driver No 1 hippie 1 13 0 0 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 19 200 7 7 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 50 352 21 21 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 82 252 28 28 0
HSPA9-201 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 47 284 19 19 2
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 45 83 1 1 2
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 2 hippie, biogrid 263 2091 107 107 20
IER3-201 IER3 P46695 Radiation-inducible immediate-early gene IEX-1 chr6 Not Cancer Driver No 1 hippie 4 106 3 3 0
KCNF1-201 KCNF1 Q9H3M0 Potassium voltage-gated channel subfamily F member 1 chr2 Not Cancer Driver No 1 hippie 86 73 9 9 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 771 7 2 2 22
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 78 85 10 10 0
MAGEA8-201 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 hippie, biogrid 51 112 16 16 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPK10-319 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 Not Cancer Driver No 1 hippie 72 107 15 15 0
MCL1-202 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 Not Cancer Driver No 1 hippie 27 204 19 19 0
MLLT11-201 MLLT11 Q13015 Protein AF1q chr1 Census Yes 1 hippie, biogrid 7 18 3 3 0
NIPAL1-201 NIPAL1 Q6NVV3 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NSFL1C-201 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie, biogrid 33 267 22 22 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OTUD1-201 OTUD1 Q5VV17 OTU domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 6 283 1 1 0
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 19 22 2 2 1
PDK2-203 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 Not Cancer Driver No 1 biogrid 32 35 1 1 0
PEBP1-201 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 17 77 11 11 0
PIN1-201 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 13 116 11 11 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 46 99 8 8 24
PMAIP1-202 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 2 hippie, biogrid 2 23 1 1 0
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 4 hippie, biogrid 54 124 13 13 0
PRKAB1-201 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 3 hippie, biogrid 21 125 11 11 0
PRKAB2-201 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 3 hippie, biogrid 20 111 8 8 0
PRKAG1-206 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 2 hippie, biogrid 27 25 2 2 0
PRKAR1A-216 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 biogrid 26 66 5 5 15
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
RANBP6-201 RANBP6 O60518 Ran-binding protein 6 chr9 Not Cancer Driver No 2 hippie, biogrid 99 46 3 3 0
RBM10-203 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie, biogrid 86 777 72 72 0
RTL10-201 RTL10 Q7L3V2 Protein Bop chr22 Not Cancer Driver No 1 hippie 35 200 17 17 0
SERPINB7-202 SERPINB7 O75635 Serpin B7 chr18 Not Cancer Driver No 2 hippie, biogrid 74 30 7 7 0
SKP1-202 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 1 hippie 20 96 19 19 0
SLC5A6-201 SLC5A6 Q9Y289 Sodium-dependent multivitamin transporter chr2 Not Cancer Driver No 1 hippie, biogrid 69 28 0 0 4
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
STARD9-201 STARD9 Q9P2P6 StAR-related lipid transfer protein 9 chr15 Not Cancer Driver No 3 hippie, biogrid 33 3412 23 23 0
STX8-201 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 1 hippie 16 99 5 5 0
TMPRSS5-201 TMPRSS5 Q9H3S3 Transmembrane protease serine 5 chr11 Not Cancer Driver No 1 hippie, biogrid 27 33 1 1 0
TNKS-201 TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 Not Cancer Driver No 1 hippie 102 483 26 26 0
TNKS2-201 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 Not Cancer Driver No 1 hippie 99 255 20 20 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TPT1-212 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 hippie 14 43 5 5 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TRIM11-201 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 Not Cancer Driver No 3 hippie, biogrid 46 132 16 16 0
TXLNG-201 TXLNG Q9NUQ3 Gamma-taxilin chrX Not Cancer Driver No 1 hippie, biogrid 33 376 25 25 0
UBXN6-201 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie 50 135 21 21 0
UHRF2-201 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 67 254 16 16 0
UNK-205 UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 60 513 33 33 0
USP13-201 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 Not Cancer Driver No 1 hippie 96 224 34 34 0
USP17L2-201 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 Not Cancer Driver No 1 hippie 82 208 48 48 0
USP9X-202 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie 243 405 33 33 1
VCPIP1-201 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 Not Cancer Driver No 1 hippie, biogrid 103 543 45 45 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie 25 36 4 4 0
YBEY-206 YBEY P58557 Endoribonuclease YbeY chr21 Not Cancer Driver No 1 hippie, biogrid 13 9 1 1 0
ZAR1L-202 ZAR1L A6NP61 Protein ZAR1-like chr13 Not Cancer Driver No 1 hippie, biogrid 13 180 7 7 0