Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 106 | 609 | 53 | 53 | 2 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 99 | 158 | 19 | 19 | 4 |
| ALB-201 | ALB | P02768 | Albumin | chr4 | Compendium | Yes | 1 | hippie | 127 | 6 | 0 | 0 | 2 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 23 | 104 | 9 | 9 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 94 | 419 | 52 | 52 | 12 |
| ARF1-201 | ARF1 | P84077 | ADP-ribosylation factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 4 | 2 | 2 | 2 |
| ASRGL1-202 | ASRGL1 | Q7L266 | Isoaspartyl peptidase/L-asparaginase | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 35 | 75 | 12 | 12 | 0 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | Census, Compendium | Yes | 1 | hippie | 358 | 226 | 29 | 29 | 41 |
| BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | Census, Compendium | Yes | 1 | intact, hippie | 21 | 73 | 5 | 5 | 0 |
| BECN1-213 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 36 | 190 | 15 | 15 | 0 |
| C1orf109-207 | AIRIM | Q9NX04 | AFG2-interacting ribosome maturation factor | chr1 | Not Cancer Driver | No | 1 | intact | 12 | 0 | 0 | 0 | 0 |
| CAPN7-201 | CAPN7 | Q9Y6W3 | Calpain-7 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 92 | 9 | 9 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | Census | Yes | 1 | hippie | 19 | 64 | 1 | 1 | 0 |
| CBLC-203 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | Census | Yes | 1 | hippie | 43 | 126 | 12 | 12 | 0 |
| CCNDBP1-201 | CCNDBP1 | O95273 | Cyclin-D1-binding protein 1 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 22 | 63 | 5 | 5 | 0 |
| CD160-202 | CD160 | O95971 | CD160 antigen | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 16 | 2 | 0 | 0 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 547 | 50 | 50 | 0 |
| CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 26 | 1 | 0 | 0 | 0 |
| CDK4-201 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 38 | 52 | 3 | 3 | 2 |
| CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | hippie | 38 | 121 | 25 | 25 | 0 |
| CDKN2A-201 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 151 | 83 | 81 | 81 | 30 |
| CDKN2B-201 | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | Not Cancer Driver | No | 1 | hippie | 14 | 67 | 2 | 2 | 0 |
| CHEK1-204 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | Not Cancer Driver | No | 2 | intact, hippie | 42 | 86 | 13 | 13 | 0 |
| CHEK2-206 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie | 72 | 157 | 19 | 19 | 11 |
| COP1-204 | COP1 | Q8NHY2 | E3 ubiquitin-protein ligase COP1 | chr1 | Not Cancer Driver | No | 1 | hippie | 81 | 148 | 5 | 5 | 0 |
| CSNK1A1-202 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 34 | 46 | 2 | 2 | 0 |
| CSNK1A1L-201 | CSNK1A1L | Q8N752 | Casein kinase I isoform alpha-like | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 46 | 2 | 2 | 0 |
| DAXX-202 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 79 | 549 | 57 | 57 | 0 |
| E2F1-201 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 39 | 273 | 17 | 17 | 0 |
| EIF2AK4-201 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 113 | 496 | 34 | 34 | 2 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 721 | 45 | 45 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 203 | 1792 | 84 | 84 | 1 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | Compendium | Yes | 1 | hippie | 147 | 188 | 33 | 33 | 3 |
| EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 74 | 284 | 32 | 32 | 11 |
| FAM193A-201 | FAM193A | P78312 | Protein FAM193A | chr4 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 125 | 921 | 88 | 88 | 0 |
| FGFR4-201 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | hippie | 101 | 163 | 27 | 27 | 0 |
| GLIS2-202 | GLIS2 | Q9BZE0 | Zinc finger protein GLIS2 | chr16 | Not Cancer Driver | No | 1 | hippie | 27 | 300 | 15 | 15 | 0 |
| HBB-201 | HBB | P68871 | Hemoglobin subunit beta | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 7 | 1 | 1 | 5 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | Compendium | Yes | 1 | hippie | 196 | 43 | 16 | 16 | 0 |
| HIPK2-202 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 124 | 686 | 76 | 76 | 0 |
| HNRNPL-201 | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 61 | 283 | 23 | 23 | 0 |
| HSP90AA1-201 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 44 | 258 | 15 | 15 | 0 |
| HSP90AB1-203 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 70 | 255 | 29 | 29 | 0 |
| KPNA3-201 | KPNA3 | O00505 | Importin subunit alpha-4 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 108 | 7 | 7 | 5 |
| LATS2-201 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie | 101 | 690 | 57 | 57 | 0 |
| LRSAM1-201 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | Not Cancer Driver | No | 1 | hippie | 71 | 240 | 24 | 24 | 1 |
| MAGEA1-201 | MAGEA1 | P43355 | Melanoma-associated antigen 1 | chrX | Not Cancer Driver | No | 1 | hippie | 48 | 71 | 12 | 12 | 0 |
| MAGEB1-202 | MAGEB1 | P43366 | Melanoma-associated antigen B1 | chrX | Not Cancer Driver | No | 1 | hippie | 72 | 173 | 20 | 20 | 0 |
| MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | Not Cancer Driver | No | 1 | hippie | 26 | 85 | 6 | 6 | 0 |
| MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 11 | intact, hippie, biogrid | 39 | 298 | 24 | 24 | 0 |
| MDM4-203 | MDM4 | O15151 | Protein Mdm4 | chr1 | Census, Compendium | Yes | 2 | intact, hippie | 33 | 203 | 15 | 15 | 1 |
| MKRN3-201 | MKRN3 | Q13064 | Probable E3 ubiquitin-protein ligase makorin-3 | chr15 | Not Cancer Driver | No | 3 | intact, hippie | 168 | 201 | 88 | 88 | 4 |
| MNAT1-201 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 64 | 2 | 2 | 0 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | Not Cancer Driver | No | 1 | hippie | 61 | 292 | 28 | 28 | 1 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | Census, Compendium | Yes | 1 | hippie | 298 | 298 | 28 | 28 | 15 |
| NAA10-208 | NAA10 | P41227 | N-alpha-acetyltransferase 10 | chrX | Not Cancer Driver | No | 1 | hippie | 29 | 117 | 16 | 16 | 3 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | Census | Yes | 1 | hippie | 63 | 420 | 45 | 45 | 1 |
| NF2-202 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 49 | 252 | 18 | 18 | 16 |
| PELI1-201 | PELI1 | Q96FA3 | E3 ubiquitin-protein ligase pellino homolog 1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 169 | 9 | 9 | 0 |
| PPARD-203 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 51 | 70 | 5 | 5 | 0 |
| PPP1CA-203 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 6 | 6 | 0 |
| PPP1CB-202 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | hippie | 33 | 25 | 4 | 4 | 4 |
| PPP1CC-201 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | Not Cancer Driver | No | 1 | hippie | 19 | 23 | 3 | 3 | 0 |
| PRKAA1-204 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 124 | 13 | 13 | 0 |
| PSMC5-201 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 64 | 5 | 5 | 0 |
| PSMD2-201 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 71 | 136 | 11 | 11 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 106 | 730 | 50 | 50 | 0 |
| RAD54B-202 | RAD54B | Q9Y620 | DNA repair and recombination protein RAD54B | chr8 | Not Cancer Driver | No | 1 | hippie | 73 | 122 | 9 | 9 | 0 |
| RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 89 | 282 | 26 | 26 | 21 |
| RCHY1-201 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 18 | 23 | 0 | 0 | 0 |
| RNF115-202 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 136 | 11 | 11 | 0 |
| RNF2-202 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 26 | 203 | 15 | 15 | 1 |
| RPL11-206 | RPL11 | P62913 | Large ribosomal subunit protein uL5 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 12 | 1 | 1 | 1 |
| RPL15-201 | RPL15 | P61313 | Large ribosomal subunit protein eL15 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 84 | 7 | 7 | 0 |
| RPL37-201 | RPL37 | P61927 | Large ribosomal subunit protein eL37 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 83 | 6 | 6 | 0 |
| RPS15-209 | RPS15 | P62841 | Small ribosomal subunit protein uS19 | chr19 | Not Cancer Driver | No | 1 | hippie | 10 | 59 | 6 | 6 | 0 |
| RPS20-201 | RPS20 | P60866 | Small ribosomal subunit protein uS10 | chr8 | Not Cancer Driver | No | 1 | hippie | 12 | 54 | 5 | 5 | 0 |
| RPS27A-201 | RPS27A | P62979 | Ubiquitin-ribosomal protein eS31 fusion protein | chr2 | Not Cancer Driver | No | 1 | intact | 13 | 47 | 2 | 2 | 0 |
| S100A1-201 | S100A1 | P23297 | Protein S100-A1 | chr1 | Not Cancer Driver | No | 1 | hippie | 10 | 9 | 0 | 0 | 0 |
| S100A2-202 | S100A2 | P29034 | Protein S100-A2 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 6 | 0 | 0 | 0 |
| S100A5-201 | S100A5 | P33763 | Protein S100-A5 | chr1 | Not Cancer Driver | No | 1 | hippie | 7 | 7 | 1 | 1 | 0 |
| S100B-201 | S100B | P04271 | Protein S100-B | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 14 | 0 | 0 | 0 |
| SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 16 | 75 | 3 | 3 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 80 | 113 | 15 | 15 | 5 |
| SMAD4-201 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | Census, Compendium | Yes | 1 | hippie | 172 | 195 | 16 | 16 | 6 |
| SMARCA2-203 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 178 | 1015 | 100 | 100 | 36 |
| SPATA46-201 | SPATA46 | Q5T0L3 | Spermatogenesis-associated protein 46 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 21 | 68 | 6 | 6 | 0 |
| SUMO1-203 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
| TOP2A-201 | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | Compendium | Yes | 1 | hippie | 115 | 509 | 46 | 46 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 14 | intact, hippie, biogrid | 2742 | 282 | 1364 | 1364 | 60 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | Census, Compendium | Yes | 1 | hippie | 198 | 398 | 120 | 120 | 21 |
| TP73-208 | TP73 | O15350 | Tumor protein p73 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 67 | 446 | 45 | 45 | 0 |
| TRIM46-201 | TRIM46 | Q7Z4K8 | Tripartite motif-containing protein 46 | chr1 | Not Cancer Driver | No | 1 | hippie | 85 | 174 | 25 | 25 | 0 |
| TRIM55-202 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 278 | 59 | 59 | 0 |
| UBA1-201 | UBA1 | P22314 | Ubiquitin-like modifier-activating enzyme 1 | chrX | Not Cancer Driver | No | 1 | hippie | 82 | 166 | 14 | 14 | 4 |
| UBC-201 | UBC | P0CG48 | Polyubiquitin-C | chr12 | Not Cancer Driver | No | 1 | intact | 80 | 320 | 42 | 42 | 0 |
| UBE2D1-201 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | Not Cancer Driver | No | 1 | hippie | 9 | 14 | 0 | 0 | 0 |
| UBE2D2-201 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | Compendium | Yes | 1 | hippie | 14 | 13 | 1 | 1 | 0 |
| UBE2D3-210 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | Not Cancer Driver | No | 1 | hippie | 15 | 13 | 3 | 3 | 0 |
| USP2-201 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 214 | 28 | 28 | 0 |
| USP22-201 | USP22 | Q9UPT9 | Ubiquitin carboxyl-terminal hydrolase 22 | chr17 | Not Cancer Driver | No | 1 | hippie | 42 | 50 | 1 | 1 | 0 |
| USP7-201 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 2 | intact, hippie | 135 | 215 | 34 | 34 | 7 |
| VPS26C-201 | VPS26C | O14972 | Vacuolar protein sorting-associated protein 26C | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 4 | 0 | 0 | 0 |
| WDR5-201 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie | 18 | 37 | 1 | 1 | 0 |
| YWHAB-201 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 110 | 3 | 3 | 0 |
| YWHAE-201 | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 4 | intact, hippie | 24 | 41 | 1 | 1 | 0 |
| YWHAG-201 | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 2 | intact, hippie | 21 | 78 | 4 | 4 | 3 |
| YWHAH-201 | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 55 | 0 | 0 | 0 |
| YWHAQ-201 | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 41 | 2 | 2 | 0 |
| YWHAZ-207 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 19 | 81 | 7 | 7 | 0 |
| ZKSCAN3-201 | ZKSCAN3 | Q9BRR0 | Zinc finger protein with KRAB and SCAN domains 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 50 | 270 | 24 | 24 | 0 |
| ZKSCAN4-201 | ZKSCAN4 | Q969J2 | Zinc finger protein with KRAB and SCAN domains 4 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 29 | 304 | 17 | 17 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|