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MIB2-201 ,MIB2 ,Q96AX9
  • Number of Interaction partner in intact: 8
  • Number of Interaction partner in biogrid: 25
  • Number of Interaction partner in hippie: 55
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA1-202 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 63 48 13 13 67
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 23 104 9 9 0
AZI2-212 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 Not Cancer Driver No 1 intact, hippie 24 192 10 10 0
BCL10-202 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 1 hippie 20 153 14 14 0
C6orf15-201 C6orf15 Q6UXA7 Uncharacterized protein C6orf15 chr6 Not Cancer Driver No 1 hippie, biogrid 47 274 40 40 0
CCT2-201 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 hippie, biogrid 51 46 4 4 0
CCT3-201 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 53 95 11 11 0
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie, biogrid 65 72 8 8 1
CCT7-201 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie, biogrid 45 36 3 3 0
CEP128-209 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 139 902 117 117 0
CFLAR-201 CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 Not Cancer Driver No 1 hippie 31 44 1 1 0
CHRNB4-201 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 Not Cancer Driver No 1 hippie, biogrid 74 30 6 6 0
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
DEFB125-201 DEFB125 Q8N687 Beta-defensin 125 chr20 Not Cancer Driver No 1 hippie, biogrid 29 54 10 10 0
DMTN-202 DMTN Q08495 Dematin chr8 Not Cancer Driver No 1 hippie, biogrid 45 348 39 39 0
ELANE-201 ELANE P08246 Neutrophil elastase chr19 Not Cancer Driver No 1 hippie, biogrid 31 18 1 1 65
F9-201 F9 P00740 Coagulation factor IX chrX Not Cancer Driver No 2 hippie, biogrid 90 40 14 14 105
GRIN2B-201 GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 hippie 331 428 116 116 12
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 24 78 5 5 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 5 301 4 4 21
IKZF1-201 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 2 hippie, biogrid 106 328 72 72 4
IKZF5-201 IKZF5 Q9H5V7 Zinc finger protein Pegasus chr10 Not Cancer Driver No 2 hippie, biogrid 30 283 25 25 0
IST1-203 IST1 P53990 IST1 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 25 188 15 15 0
JAG2-201 JAG2 Q9Y219 Protein jagged-2 chr14 Not Cancer Driver No 1 hippie 109 159 22 22 1
KCNH2-201 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 148 467 41 41 102
LOXL4-201 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 74 123 5 5 0
LYPD6B-204 LYPD6B Q8NI32 Ly6/PLAUR domain-containing protein 6B chr2 Not Cancer Driver No 1 hippie, biogrid 24 3 2 2 0
MACC1-202 MACC1 Q6ZN28 Metastasis-associated in colon cancer protein 1 chr7 Census Yes 1 hippie, biogrid 115 93 12 12 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 74 333 42 42 6
MAVS-202 MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 55 415 44 44 0
MIB1-201 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 intact, hippie 96 284 26 26 1
NAF1-201 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 Not Cancer Driver No 1 intact, hippie 48 388 33 33 0
NCL-201 NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 intact, hippie 32 569 20 20 0
NUP58-202 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 hippie 48 379 35 35 0
P2RY1-201 P2RY1 P47900 P2Y purinoceptor 1 chr3 Not Cancer Driver No 2 hippie, biogrid 44 16 0 0 0
PI15-201 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 66 4 1 1 0
PLPPR4-202 PLPPR4 Q7Z2D5 Phospholipid phosphatase-related protein type 4 chr1 Not Cancer Driver No 1 hippie 156 419 103 103 0
PMCH-201 PMCH P20382 Pro-MCH chr12 Not Cancer Driver No 1 hippie, biogrid 12 63 6 6 0
RIPK1-201 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 intact, hippie, biogrid 59 277 28 28 1
SRP14-201 SRP14 P37108 Signal recognition particle 14 kDa protein chr15 Not Cancer Driver No 1 hippie, biogrid 3 74 1 1 0
SRPK2-201 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie 57 344 31 31 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact, hippie 68 42 4 4 12
TMEM74-201 TMEM74 Q96NL1 Transmembrane protein 74 chr8 Not Cancer Driver No 1 hippie, biogrid 79 129 36 36 0
TNF-208 TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 22 45 2 2 0
TNRC6A-202 TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 1 hippie 203 1830 191 191 0
TNRC6C-203 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 Not Cancer Driver No 1 hippie 0 0 0 0 0
TRIP6-201 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 hippie, biogrid 48 270 14 14 0
UBE2D2-201 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 14 13 1 1 0
UBE2N-201 UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 19 24 1 1 0
UBE2U-206 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 Not Cancer Driver No 1 intact, hippie 30 66 1 1 0
XRCC5-201 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 intact, hippie 53 119 6 6 0
ZC3H7A-201 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 63 225 17 17 0