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MPZL1-201 ,MPZL1 ,O95297
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 108
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABTB2-201 ABTB2 Q8N961 Ankyrin repeat and BTB/POZ domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 76 215 17 17 0
ACTBL2-201 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 60 29 3 3 0
ALDH1A2-201 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 72 56 12 12 3
AMIGO1-202 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 37 85 5 5 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
BAIAP2-202 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 60 332 43 43 0
BTNL9-201 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 53 87 3 3 0
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
C6orf136-203 C6orf136 Q5SQH8 Uncharacterized protein C6orf136 chr6 Not Cancer Driver No 1 hippie, biogrid 24 119 5 5 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CD81-201 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 22 0 0 0 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHRNA4-201 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 112 188 26 26 1
CLEC4A-201 CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 Not Cancer Driver No 1 hippie, biogrid 24 22 4 4 0
CLGN-201 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 56 257 24 24 0
CPA2-201 CPA2 P48052 Carboxypeptidase A2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 47 26 1 1 0
CPA5-206 CPA5 Q8WXQ8 Carboxypeptidase A5 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 51 40 1 1 0
CRKL-201 CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 intact, hippie 24 160 17 17 0
CRLF2-202 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX Census Yes 1 hippie, biogrid 37 62 0 0 0
CTDSPL-201 CTDSPL O15194 CTD small phosphatase-like protein chr3 Not Cancer Driver No 1 intact, hippie 26 60 2 2 0
CTLA4-204 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 1
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
CYP2S1-201 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 59 46 8 8 0
DIRAS3-202 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 27 21 2 2 0
DOK7-201 DOK7 Q18PE1 Protein Dok-7 chr4 Not Cancer Driver No 1 hippie 34 294 14 14 17
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ENST00000649896 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 1 hippie, biogrid 45 121 15 15 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EVA1B-202 EVA1B Q9NVM1 Protein eva-1 homolog B chr1 Not Cancer Driver No 1 hippie, biogrid 16 118 9 9 0
EXOSC4-201 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 intact, hippie 26 23 0 0 0
FBXO7-201 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 49 243 24 24 1
FCGRT-201 FCGRT P55899 IgG receptor FcRn large subunit p51 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 48 65 9 9 0
FHL3-201 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie 28 0 0 0 0
FTO-206 FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 Not Cancer Driver No 1 intact, hippie, biogrid 50 54 10 10 3
FZD4-201 FZD4 Q9ULV1 Frizzled-4 chr11 Not Cancer Driver No 1 hippie, biogrid 40 33 5 5 17
GGT7-201 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 69 170 14 14 0
GPRC5D-201 GPRC5D Q9NZD1 G-protein coupled receptor family C group 5 member D chr12 Not Cancer Driver No 1 hippie, biogrid 23 32 0 0 0
GYPA-213 GYPA P02724 Glycophorin-A chr4 Not Cancer Driver No 1 hippie, biogrid 28 90 23 23 0
HCCS-202 HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 3 hippie, biogrid 46 117 24 24 1
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 30 135 5 5 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie, biogrid 129 16 2 2 10
HSD17B1-202 HSD17B1 P14061 17-beta-hydroxysteroid dehydrogenase type 1 chr17 Not Cancer Driver No 1 hippie, biogrid 33 58 4 4 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie, biogrid 82 252 28 28 0
IFIH1-206 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 83 288 27 27 9
IPPK-201 IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 Not Cancer Driver No 2 intact, hippie, biogrid 32 43 0 0 0
KCNJ2-201 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 85 49 7 7 12
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 intact 44 61 6 6 6
KIF7-201 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 intact, hippie 110 848 74 74 5
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 771 7 2 2 22
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 36 94 8 8 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LGALS3-201 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 9 133 0 0 0
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 3 hippie, biogrid 46 65 13 13 0
LIPF-201 LIPF P07098 Gastric triacylglycerol lipase chr10 Not Cancer Driver No 3 intact, hippie, biogrid 52 0 0 0 0
LY6G5B-207 LY6G5B Q8NDX9 Lymphocyte antigen 6 complex locus protein G5b chr6 Not Cancer Driver No 1 hippie, biogrid 2 2 0 0 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 8 46 2 2 0
MFF-204 MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 intact, hippie 41 267 32 32 0
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie, biogrid 24 45 3 3 0
MYO5C-201 MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 138 395 31 31 0
NHLRC3-202 NHLRC3 Q5JS37 NHL repeat-containing protein 3 chr13 Not Cancer Driver No 1 hippie, biogrid 26 7 0 0 0
NOXRED1-201 NOXRED1 Q6NXP6 NADP-dependent oxidoreductase domain-containing protein 1 chr14 Not Cancer Driver No 3 hippie, biogrid 36 4 1 1 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NUP98-203 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 161 1012 78 78 0
PACC1-201 PACC1 Q9H813 Proton-activated chloride channel chr1 Not Cancer Driver No 1 intact 37 32 2 2 0
PICK1-201 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie, biogrid 36 49 1 1 0
PLAC9-201 PLAC9 Q5JTB6 Placenta-specific protein 9 chr10 Not Cancer Driver No 1 hippie, biogrid 8 46 5 5 0
POLA2-201 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 1 hippie, biogrid 49 102 15 15 0
PRPH2-201 PRPH2 P23942 Peripherin-2 chr6 Not Cancer Driver No 1 hippie, biogrid 42 35 2 2 36
PTPN11-201 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 4 intact, hippie, biogrid 92 260 27 27 44
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 50 20 1 1 0
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 16 10 0 0 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 32 12 3 3 0
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
SAAL1-202 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 1 hippie, biogrid 36 75 8 8 0
SFTPC-213 SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 2 hippie, biogrid 15 22 2 2 5
SIGLECL1-207 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 44 35 12 12 0
SLC39A4-202 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 58 116 9 9 9
SPACA1-201 SPACA1 Q9HBV2 Sperm acrosome membrane-associated protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 55 79 7 7 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 93 152 16 16 15
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 21 165 9 9 0
TECR-201 TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 1
TGFA-201 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMEM17-201 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 15 14 1 1 0
TMEM30B-202 TMEM30B Q3MIR4 Cell cycle control protein 50B chr14 Not Cancer Driver No 2 hippie, biogrid 13 17 0 0 0
TMEM65-201 TMEM65 Q6PI78 Transmembrane protein 65 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 14 50 0 0 0
TMPRSS11B-201 TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 77 5 0 0 0
TNPO2-202 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 77 76 9 9 10
TOLLIP-202 TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 25 82 9 9 0
TRIM55-202 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 100 278 59 59 0
TRIM63-201 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 26 71 6 6 0
TRPC4AP-201 TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 Not Cancer Driver No 1 intact, hippie, biogrid 64 70 3 3 0
TSPAN31-201 TSPAN31 Q12999 Tetraspanin-31 chr12 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
VAC14-201 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 76 117 17 17 3
VIPR1-201 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 27 10 0 0 0
ZNG1A-202 ZNG1A Q9BRT8 Zinc-regulated GTPase metalloprotein activator 1A chr9 Not Cancer Driver No 1 intact 20 59 4 4 0