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NDUFS2-224 ,NDUFS2 ,O75306
  • Number of Interaction partner in intact: 57
  • Number of Interaction partner in biogrid: 151
  • Number of Interaction partner in hippie: 258
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2-201 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 91 203 23 23 5
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 2 intact, hippie, biogrid 54 28 2 2 12
ADRB2-201 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 36 35 4 4 0
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 hippie 91 142 12 12 10
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 61 166 20 20 10
AKTIP-202 AKTIP Q9H8T0 AKT-interacting protein chr16 Not Cancer Driver No 1 hippie 14 96 5 5 0
ALDOA-206 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 intact 36 65 7 7 3
AMBRA1-213 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 132 790 80 80 0
ANKRD34C-201 ANKRD34C P0C6C1 Ankyrin repeat domain-containing protein 34C chr15 Not Cancer Driver No 1 hippie, biogrid 18 408 15 15 0
APOO-201 APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 21 23 4 4 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARMC8-210 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 42 7 0 0 0
ATP5F1B-201 ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 85 7 7 1
ATP5F1C-202 ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 27 11 0 0 0
ATP5PB-202 ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 Not Cancer Driver No 1 hippie 25 2 0 0 0
ATP6V1A-201 ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 65 31 0 0 4
AUH-202 AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 29 0 0 1
AURKAIP1-202 AURKAIP1 Q9NWT8 Small ribosomal subunit protein mS38 chr1 Not Cancer Driver No 1 hippie 17 104 8 8 0
BCKDHA-201 BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 17 17 11
BCL2L14-203 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 20 40 4 4 0
BFAR-201 BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 Not Cancer Driver No 1 hippie 50 30 1 1 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
C15orf48-202 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 9 10 1 1 0
C17orf80-205 C17orf80 Q9BSJ5 Uncharacterized protein C17orf80 chr17 Not Cancer Driver No 1 hippie, biogrid 44 458 37 37 0
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 5 5 2
C8orf82-202 C8orf82 Q6P1X6 UPF0598 protein C8orf82 chr8 Not Cancer Driver No 1 hippie, biogrid 9 11 0 0 0
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 28 245 16 16 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 57 334 36 36 0
CCDC90B-214 CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 23 77 4 4 0
CENPU-201 CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 intact, hippie 23 302 19 19 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CGRRF1-201 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 1 hippie 20 34 4 4 0
CHCHD1-201 CHCHD1 Q96BP2 Small ribosomal subunit protein mS37 chr10 Not Cancer Driver No 1 hippie, biogrid 8 67 6 6 0
CISD3-204 CISD3 P0C7P0 CDGSH iron-sulfur domain-containing protein 3, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie, biogrid 5 31 0 0 0
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 15 83 7 7 3
COA3-201 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 3 57 2 2 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
COQ10A-201 COQ10A Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial chr12 Not Cancer Driver No 1 hippie 16 28 0 0 0
COQ7-201 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 16 5 0 0 1
COQ9-201 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 25 111 5 5 0
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 41 84 12 12 0
COX14-203 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 2
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 13 5 1 1 1
COX6B1-204 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 14 23 5 5 1
COX6C-205 COX6C P09669 Cytochrome c oxidase subunit 6C chr8 Census Yes 1 hippie, biogrid 9 0 0 0 0
COX7A2-209 COX7A2 P14406 Cytochrome c oxidase subunit 7A2, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 1 14 0 0 0
COX7A2L-201 COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
COX7C-201 COX7C P15954 Cytochrome c oxidase subunit 7C, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 5 0 0 0 0
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CPSF7-202 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie, biogrid 39 398 37 37 0
CRYZ-201 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 38 13 2 2 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CYC1-201 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 44 35 2 2 2
DDX28-201 DDX28 Q9NUL7 Probable ATP-dependent RNA helicase DDX28 chr16 Not Cancer Driver No 1 hippie, biogrid 31 127 4 4 0
DHRS4-201 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 Not Cancer Driver No 2 hippie, biogrid 21 38 4 4 0
DHX30-205 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie, biogrid 107 260 29 29 5
DLAT-201 DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 50 297 35 35 0
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 55 17 0 0 10
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 61 378 23 23 0
DNAJA3-201 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 44 152 19 19 0
DNAJC15-201 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 15 25 2 2 0
DNAJC19-201 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 Not Cancer Driver No 1 hippie, biogrid 14 27 3 3 0
DNAJC28-202 DNAJC28 Q9NX36 DnaJ homolog subfamily C member 28 chr21 Not Cancer Driver No 1 hippie, biogrid 37 139 7 7 0
DNAJC30-201 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 2 hippie, biogrid 13 83 3 3 3
ECI2-202 ECI2 O75521 Enoyl-CoA delta isomerase 2 chr6 Not Cancer Driver No 1 hippie 44 70 5 5 0
ECSIT-202 ECSIT Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 50 146 25 25 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EGR2-201 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 Compendium Yes 1 hippie 58 352 38 38 10
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 77 61 4 4 2
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 38 29 2 2 0
ENST00000598884 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 14 104 10 10 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
EXD2-214 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 47 178 12 12 0
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 36 171 11 11 0
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FASTKD2-202 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 49 30 2 2 0
FASTKD3-201 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 83 6 1 1 0
FASTKD5-201 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 58 94 3 3 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FHIP1B-202 FHIP1B Q8N612 FHF complex subunit HOOK-interacting protein 1B chr11 Not Cancer Driver No 1 intact 97 420 42 42 0
FHIP2B-201 FHIP2B Q86V87 FHF complex subunit HOOK-interacting protein 2B chr8 Not Cancer Driver No 1 intact 46 140 10 10 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GFM1-210 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 49 79 5 5 4
GFM2-201 GFM2 Q969S9 Ribosome-releasing factor 2, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 61 100 6 6 2
GOLT1B-201 GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 intact, hippie 14 0 0 0 0
GPR45-201 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 75 0 0 0 0
GRSF1-201 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 2 hippie, biogrid 33 147 15 15 0
HADHA-201 HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 0 0 5
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 54 41 9 9 12
HINT2-201 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 6 29 1 1 0
HMOX2-208 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 intact, hippie 17 74 5 5 0
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 2 intact, hippie, biogrid 23 25 3 3 0
HSP90B1-201 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 56 269 17 17 0
HSPA1L-201 HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 86 141 23 23 0
HSPA9-201 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 47 284 19 19 2
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 45 83 1 1 2
HTRA2-201 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 33 127 7 7 2
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
IMMP1L-209 IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 15 3 0 0 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
IMMT-204 IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 75 402 39 39 0
IRF2-201 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 intact, hippie 60 290 52 52 0
ITFG1-201 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 50 18 3 3 0
ITM2B-204 ITM2B Q9Y287 Integral membrane protein 2B chr13 Not Cancer Driver No 1 intact 15 12 0 0 1
KCND3-201 KCND3 Q9UK17 Potassium voltage-gated channel subfamily D member 3 chr1 Not Cancer Driver No 1 hippie 127 203 30 30 5
KDF1-201 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 43 279 35 35 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
LACTB-201 LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 29 123 2 2 0
LMAN2-201 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie, biogrid 37 36 6 6 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LONP1-201 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 75 178 16 16 10
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 99 18 0 0 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAD2L2-207 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 16 0 0 0 1
MAIP1-202 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 23 12 0 0 0
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 104 593 69 69 0
MCU-202 MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 13 0 0 0
MCUB-201 MCUB Q9NWR8 Calcium uniporter regulatory subunit MCUb, mitochondrial chr4 Not Cancer Driver No 1 hippie 22 24 0 0 0
MCUR1-201 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 66 0 0 0
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
METTL15-204 METTL15 A6NJ78 12S rRNA N4-methylcytidine (m4C) methyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 35 92 11 11 0
METTL17-201 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 48 95 10 10 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MKLN1-201 MKLN1 Q9UL63 Muskelin chr7 Not Cancer Driver No 2 intact, hippie 51 91 9 9 0
MMS19-209 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 54 11 0 0 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MRPL11-201 MRPL11 Q9Y3B7 Large ribosomal subunit protein uL11m chr11 Not Cancer Driver No 1 hippie, biogrid 20 12 2 2 0
MRPL58-201 MRPL58 Q14197 Large ribosomal subunit protein mL62 chr17 Not Cancer Driver No 1 intact, hippie 26 106 11 11 0
MRPS12-201 MRPS12 O15235 Small ribosomal subunit protein uS12m chr19 Not Cancer Driver No 1 hippie, biogrid 14 59 8 8 0
MRPS21-202 MRPS21 P82921 Small ribosomal subunit protein bS21m chr1 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
MRPS26-201 MRPS26 Q9BYN8 Small ribosomal subunit protein mS26 chr20 Not Cancer Driver No 1 hippie, biogrid 12 102 4 4 0
MRRF-202 MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 13 118 6 6 0
MTCH1-202 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 21 102 1 1 0
MTCH2-201 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 2 hippie, biogrid 27 11 0 0 0
MTERF3-201 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 35 62 4 4 0
MTFMT-201 MTFMT Q96DP5 Methionyl-tRNA formyltransferase, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 29 56 3 3 3
MTG1-201 MTG1 Q9BT17 Mitochondrial ribosome-associated GTPase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 29 16 2 2 0
MTG2-201 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 43 48 7 7 0
MTIF2-201 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 114 7 7 0
MTIF3-202 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 15 180 11 11 0
MTRF1-203 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 33 72 4 4 0
MTRF1L-203 MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 17 185 5 5 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYL12A-201 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 hippie, biogrid 14 70 9 9 0
NDUFA1-201 NDUFA1 O15239 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 chrX Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 2
NDUFA10-201 NDUFA10 O95299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 32 19 0 0 1
NDUFA11-201 NDUFA11 Q86Y39 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 chr19 Not Cancer Driver No 1 intact, hippie 2 0 0 0 0
NDUFA12-201 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 14 31 5 5 0
NDUFA13-204 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 27 24 6 6 1
NDUFA2-201 NDUFA2 O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 chr5 Not Cancer Driver No 2 intact, hippie 8 0 0 0 0
NDUFA4-201 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 8 4 0 0 0
NDUFA6-202 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 Not Cancer Driver No 1 hippie 3 14 0 0 1
NDUFA7-201 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 14 104 10 10 0
NDUFA8-201 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 20 33 1 1 2
NDUFA9-201 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 3 hippie, biogrid 37 8 0 0 2
NDUFAB1-201 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact 16 0 0 0 0
NDUFAF3-202 NDUFAF3 Q9BU61 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 chr3 Not Cancer Driver No 2 intact, hippie 17 33 3 3 3
NDUFAF4-201 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 8 47 3 3 2
NDUFAF5-202 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 1 hippie 36 69 11 11 3
NDUFAF7-201 NDUFAF7 Q7L592 Protein arginine methyltransferase NDUFAF7, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 37 19 2 2 1
NDUFAF8-201 NDUFAF8 A1L188 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 chr17 Not Cancer Driver No 1 hippie 0 0 0 0 0
NDUFB11-202 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 20 51 6 6 1
NDUFB3-201 NDUFB3 O43676 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 chr2 Not Cancer Driver No 1 hippie, biogrid 11 17 0 0 1
NDUFB5-201 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 23 9 1 1 0
NDUFS1-201 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 3 hippie, biogrid 58 40 3 3 2
NDUFS3-201 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 10 intact, hippie, biogrid 22 26 2 2 2
NDUFS4-201 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 18 93 12 12 1
NDUFS5-202 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 11 31 3 3 0
NDUFS6-201 NDUFS6 O75380 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial chr5 Not Cancer Driver No 3 hippie, biogrid 12 8 0 0 1
NDUFS7-201 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 2 hippie, biogrid 30 31 2 2 1
NDUFS8-201 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 Not Cancer Driver No 2 hippie, biogrid 22 37 3 3 3
NDUFV1-201 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 3 hippie, biogrid 45 57 3 3 3
NDUFV2-201 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 4 hippie, biogrid 30 70 10 10 0
NDUFV3-201 NDUFV3 P56181 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 4 95 4 4 0
NGRN-202 NGRN Q9NPE2 Neugrin chr15 Not Cancer Driver No 1 hippie, biogrid 16 216 14 14 0
NIT1-203 NIT1 Q86X76 Deaminated glutathione amidase chr1 Not Cancer Driver No 1 hippie 31 18 2 2 0
NPLOC4-201 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 58 48 6 6 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NT5C3A-209 NT5C3A Q9H0P0 Cytosolic 5'-nucleotidase 3A chr7 Compendium Yes 1 intact, hippie 26 0 0 0 8
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 25 169 19 19 0
OGDH-201 OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie, biogrid 120 106 18 18 0
OMA1-201 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 39 35 3 3 0
OPA3-201 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 3 44 0 0 2
OSMR-201 OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 Not Cancer Driver No 1 hippie 115 145 15 15 5
OTC-201 OTC P00480 Ornithine transcarbamylase, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 53 24 3 3 92
OTULINL-201 OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 34 21 0 0 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
PARL-202 PARL Q9H300 Presenilin-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 38 28 5 5 0
PCCB-201 PCCB P05166 Propionyl-CoA carboxylase beta chain, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 41 64 8 8 24
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 19 22 2 2 1
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 40 43 4 4 19
PDHB-201 PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 20 4 0 0 2
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 32 49 7 7 0
PHB1-201 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 21 4 1 1 0
PHB2-203 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 26 4 4 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 129 925 106 106 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 48 23 3 3 4
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 36 22 2 2 4
POU5F1-201 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 27 186 8 8 0
PPT1-219 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 27 0 0 0 22
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PTPMT1-202 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 Not Cancer Driver No 1 intact, hippie 12 0 0 0 0
RAB5IF-203 RAB5IF Q9BUV8 GEL complex subunit OPTI chr20 Not Cancer Driver No 1 hippie 1 13 0 0 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 61 2 0 0 6
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RMND1-202 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 34 85 7 7 1
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RPUSD3-201 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 Not Cancer Driver No 1 hippie, biogrid 26 81 5 5 0
RPUSD4-201 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 44 98 15 15 0
SCCPDH-201 SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 50 26 1 1 0
SCO1-201 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 27 79 6 6 1
SDHA-201 SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 hippie, biogrid 87 72 9 9 7
SDHC-202 SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 Census Yes 1 hippie, biogrid 10 0 0 0 0
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 21 29 0 0 0
SHMT2-201 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 45 58 4 4 1
SIRT4-201 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 31 4 0 0 0
SLC25A51-201 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 19 21 0 0 0
SLIRP-209 SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 2 41 0 0 0
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SPATA20-202 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie 70 164 16 16 0
SPPL2B-209 SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 0 101 0 0 0
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 intact, hippie 41 271 24 24 30
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 6
SURF1-201 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 14 82 5 5 9
SYVN1-203 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 25 284 0 0 0
TACO1-201 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 20 111 2 2 0
TBRG4-201 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 56 61 1 1 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TEFM-205 TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 19 26 3 3 0
TFAM-204 TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 2 hippie, biogrid 19 110 11 11 1
TIMM29-201 TIMM29 Q9BSF4 Mitochondrial import inner membrane translocase subunit Tim29 chr19 Not Cancer Driver No 1 hippie 9 4 1 1 0
TIMMDC1-208 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 2 hippie, biogrid 37 51 4 4 0
TMEM70-201 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 17 24 1 1 1
TNFRSF10A-201 TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 39 175 14 14 0
TNFRSF14-201 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 intact, hippie 26 54 4 4 0
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 11 83 5 5 0
TOMM40-203 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 15 98 0 0 0
TOMM5-201 TOMM5 Q8N4H5 Mitochondrial import receptor subunit TOM5 homolog chr9 Not Cancer Driver No 1 hippie, biogrid 2 0 0 0 0
TRAP1-201 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 110 6 6 0
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 40 124 11 11 0
TRUB2-201 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 73 6 6 0
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 36 51 4 4 1
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 64 581 61 61 8
UNC93B1-201 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 42 127 3 3 0
UQCRC1-201 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 41 55 3 3 2
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 31 48 5 5 1
UQCRQ-203 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 8 12 1 1 1
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 intact, hippie 20 184 11 11 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 25 36 4 4 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 22 9 1 1 0
VDAC3-201 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
VWA8-203 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 Not Cancer Driver No 1 hippie, biogrid 153 384 24 24 0
ZNF598-202 ZNF598 Q86UK7 E3 ubiquitin-protein ligase ZNF598 chr16 Not Cancer Driver No 1 hippie 68 567 47 47 0
ZNF782-204 ZNF782 Q6ZMW2 Zinc finger protein 782 chr9 Not Cancer Driver No 1 hippie, biogrid 57 295 21 21 0