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NPPA-202 ,NPPA ,P01160
  • Number of Interaction partner in intact: 27
  • Number of Interaction partner in biogrid: 39
  • Number of Interaction partner in hippie: 54
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2ML1-201 A2ML1 A8K2U0 Alpha-2-macroglobulin-like protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 194 98 18 18 0
ACADVL-203 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 2 intact, hippie, biogrid 30 101 2 2 34
ACP3-201 ACP3 P15309 Prostatic acid phosphatase chr3 Not Cancer Driver No 1 intact 59 24 3 3 0
ALOX12B-204 ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 Not Cancer Driver No 2 intact, hippie, biogrid 74 16 2 2 18
ALOX15B-202 ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 78 64 12 12 0
ARG1-203 ARG1 P05089 Arginase-1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 27 83 8 8 9
CAPNS2-201 CAPNS2 Q96L46 Calpain small subunit 2 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 13 56 1 1 0
CPA4-201 CPA4 Q9UI42 Carboxypeptidase A4 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 69 59 9 9 0
CST6-201 CST6 Q15828 Cystatin-M chr11 Not Cancer Driver No 1 intact, hippie, biogrid 16 29 1 1 0
CTPS2-201 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 1 hippie, biogrid 39 65 7 7 0
CTSV-201 CTSV O60911 Cathepsin L2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 38 7 1 1 0
ECM1-202 ECM1 Q16610 Extracellular matrix protein 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 66 224 23 23 1
EPB41-201 EPB41 P11171 Protein 4.1 chr1 Not Cancer Driver No 1 hippie 69 557 48 48 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
GDPD3-202 GDPD3 Q7L5L3 Lysophospholipase D GDPD3 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 38 12 2 2 0
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 113 127 44 44 5
HSF2BP-201 HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 27 23 0 0 1
IMPA2-201 IMPA2 O14732 Inositol monophosphatase 2 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 35 21 1 1 0
IPO4-201 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie, biogrid 78 87 3 3 0
ISCA2-204 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 38 0 0 1
IVL-201 IVL P07476 Involucrin chr1 Not Cancer Driver No 2 intact, hippie, biogrid 28 589 28 28 0
JUP-203 JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 2 intact, hippie, biogrid 81 242 24 24 0
LCN2-201 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 Not Cancer Driver No 2 intact, hippie, biogrid 20 4 3 3 0
MAGEA12-202 MAGEA12 P43365 Melanoma-associated antigen 12 chrX Not Cancer Driver No 1 hippie 91 102 35 35 0
ME1-201 ME1 P48163 NADP-dependent malic enzyme chr6 Not Cancer Driver No 1 intact, hippie, biogrid 84 65 7 7 0
METAP1-201 METAP1 P53582 Methionine aminopeptidase 1 chr4 Not Cancer Driver No 2 hippie, biogrid 25 61 2 2 0
MME-201 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 156 40 17 17 4
NDUFAF5-202 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 2 hippie, biogrid 36 69 11 11 3
NDUFAF7-201 NDUFAF7 Q7L592 Protein arginine methyltransferase NDUFAF7, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 37 19 2 2 1
NME2-205 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
NPR1-202 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 Not Cancer Driver No 1 hippie 105 78 16 16 0
NPR2-201 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 Not Cancer Driver No 1 hippie 106 91 9 9 20
NPR3-201 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 Not Cancer Driver No 1 hippie 79 58 7 7 2
NR5A2-203 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 Not Cancer Driver No 1 hippie 99 155 28 28 0
NUDT8-202 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 20 70 10 10 0
OBSCN-204 OBSCN Q5VST9 Obscurin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 914 2651 286 286 0
PDF-201 PDF Q9HBH1 Peptide deformylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 2 8 0 0 0
PM20D1-201 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 Not Cancer Driver No 1 hippie, biogrid 54 43 7 7 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 2 intact, hippie, biogrid 48 23 3 3 4
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 2 hippie, biogrid 36 22 2 2 4
PMVK-201 PMVK Q15126 Phosphomevalonate kinase chr1 Not Cancer Driver No 2 intact, hippie, biogrid 29 3 0 0 0
POF1B-201 POF1B Q8WVV4 Protein POF1B chrX Not Cancer Driver No 1 intact, hippie, biogrid 121 386 82 82 1
RORB-202 RORB Q92753 Nuclear receptor ROR-beta chr9 Not Cancer Driver No 1 hippie 75 87 15 15 1
S100A9-201 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie, biogrid 16 76 8 8 0
SDR9C7-201 SDR9C7 Q8NEX9 Short-chain dehydrogenase/reductase family 9C member 7 chr12 Not Cancer Driver No 2 hippie, biogrid 37 3 0 0 2
SERPINB3-201 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 116 47 23 23 0
SERPINB4-201 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 2 hippie, biogrid 101 48 16 16 0
SMYD2-201 SMYD2 Q9NRG4 N-lysine methyltransferase SMYD2 chr1 Not Cancer Driver No 2 hippie, biogrid 27 12 0 0 0
TGM1-201 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 2 hippie, biogrid 88 230 25 25 50
TMEM63C-201 TMEM63C Q9P1W3 Calcium permeable stress-gated cation channel 1 chr14 Not Cancer Driver No 1 hippie, biogrid 84 85 10 10 0
TRPC4AP-201 TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 Not Cancer Driver No 1 hippie, biogrid 64 70 3 3 0
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 40 545 38 38 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 intact, hippie 64 581 61 61 8
UBQLN4-201 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 Not Cancer Driver No 1 intact, hippie 37 563 35 35 1
VGF-201 VGF O15240 Neurosecretory protein VGF chr7 Not Cancer Driver No 1 hippie, biogrid 20 593 20 20 0