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NRDC-201 ,NRDC ,O43847
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 111
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ACP6-205 ACP6 Q9NPH0 Lysophosphatidic acid phosphatase type 6 chr1 Not Cancer Driver No 1 hippie 38 40 3 3 0
ADCK2-201 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 hippie 46 9 1 1 0
ANKEF1-202 ANKEF1 Q9NU02 Ankyrin repeat and EF-hand domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 87 130 13 13 0
APOOL-201 APOOL Q6UXV4 MICOS complex subunit MIC27 chrX Not Cancer Driver No 1 hippie 22 91 7 7 0
ATM-229 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 intact, hippie 358 226 29 29 41
ATP5F1A-202 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 intact, hippie 48 23 3 3 2
AURKAIP1-202 AURKAIP1 Q9NWT8 Small ribosomal subunit protein mS38 chr1 Not Cancer Driver No 1 hippie 17 104 8 8 0
BAIAP2-202 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 60 332 43 43 0
BATF3-201 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 Not Cancer Driver No 1 intact, hippie 12 129 12 12 0
BOLA1-202 BOLA1 Q9Y3E2 BolA-like protein 1 chr1 Not Cancer Driver No 1 hippie 24 71 10 10 0
BOLA3-202 BOLA3 Q53S33 BolA-like protein 3 chr2 Not Cancer Driver No 1 hippie 7 27 0 0 2
BRD1-202 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 117 424 47 47 0
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 intact, hippie 57 45 3 3 0
CALCA-201 CALCA P01258 Calcitonin chr11 Not Cancer Driver No 1 hippie 29 80 20 20 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 31 213 13 13 0
CDRT15-201 CDRT15 Q96T59 CMT1A duplicated region transcript 15 protein chr17 Not Cancer Driver No 1 intact, hippie 18 98 6 6 0
CHCHD1-201 CHCHD1 Q96BP2 Small ribosomal subunit protein mS37 chr10 Not Cancer Driver No 1 hippie 8 67 6 6 0
CHCHD2-201 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 intact, hippie 10 114 7 7 1
CISD3-204 CISD3 P0C7P0 CDGSH iron-sulfur domain-containing protein 3, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 5 31 0 0 0
COBLL1-225 COBLL1 Q53SF7 Cordon-bleu protein-like 1 chr2 Not Cancer Driver No 1 hippie 118 956 104 104 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
COQ10A-201 COQ10A Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial chr12 Not Cancer Driver No 1 hippie 16 28 0 0 0
COQ6-201 COQ6 Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 41 21 2 2 3
COQ7-201 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 16 5 0 0 1
COQ9-201 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie 25 111 5 5 0
DEF8-201 DEF8 Q6ZN54 Differentially expressed in FDCP 8 homolog chr16 Not Cancer Driver No 1 intact, hippie 43 124 18 18 0
DHRS4-201 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 Not Cancer Driver No 1 hippie 21 38 4 4 0
DNAJC7-203 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie 26 102 8 8 0
DUSP5-201 DUSP5 Q16690 Dual specificity protein phosphatase 5 chr10 Not Cancer Driver No 1 hippie 46 36 3 3 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ELAC2-201 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 Not Cancer Driver No 1 hippie 69 208 25 25 10
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
ERMAP-203 ERMAP Q96PL5 Erythroid membrane-associated protein chr1 Not Cancer Driver No 1 hippie 40 48 3 3 0
ERP44-201 ERP44 Q9BS26 Endoplasmic reticulum resident protein 44 chr9 Not Cancer Driver No 1 intact, hippie 33 43 3 3 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
FMC1-201 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 intact, hippie 8 30 1 1 0
FMR1NB-201 FMR1NB Q8N0W7 FMR1 neighbor protein chrX Not Cancer Driver No 2 intact, hippie 60 90 24 24 0
HBEGF-201 HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 Not Cancer Driver No 1 hippie 11 63 2 2 0
HDAC3-201 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 42 61 5 5 0
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 19
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 45 83 1 1 2
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
IQGAP1-201 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie 137 351 25 25 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KIF7-201 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 intact, hippie 110 848 74 74 5
KLRK1-201 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 Not Cancer Driver No 1 hippie 35 0 0 0 0
KPNA3-201 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 hippie 47 108 7 7 5
LGALS3BP-201 LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 intact, hippie 49 9 0 0 0
LMO1-201 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie 13 0 0 0 0
LPIN2-204 LPIN2 Q92539 Phosphatidate phosphatase LPIN2 chr18 Not Cancer Driver No 1 hippie 93 455 51 51 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
LUC7L-201 LUC7L Q9NQ29 Putative RNA-binding protein Luc7-like 1 chr16 Not Cancer Driver No 2 intact, hippie 12 254 7 7 0
LYRM4-201 LYRM4 Q9HD34 LYR motif-containing protein 4 chr6 Not Cancer Driver No 1 hippie 7 11 1 1 1
MAD1L1-201 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 82 526 55 55 0
METTL25-201 METTL25 Q8N6Q8 Probable methyltransferase-like protein 25 chr12 Not Cancer Driver No 1 intact, hippie 52 152 14 14 0
MOB1A-201 MOB1A Q9H8S9 MOB kinase activator 1A chr2 Not Cancer Driver No 1 hippie 12 11 0 0 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MSH2-201 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 hippie 55 37 1 1 63
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NCOR1-201 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 265 2348 258 258 0
NCOR2-202 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 1 hippie 167 2369 167 167 0
NDUFA4-201 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie 8 4 0 0 0
NDUFS3-201 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 22 26 2 2 2
NFE2L2-201 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 1 intact 235 402 59 59 4
NLGN3-201 NLGN3 Q9NZ94 Neuroligin-3 chrX Not Cancer Driver No 1 intact, hippie 121 257 41 41 2
NME4-201 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 Not Cancer Driver No 1 hippie 10 43 5 5 0
NRDC-201 NRDC O43847 Nardilysin chr1 Not Cancer Driver No 1 hippie 117 253 22 22 0
NSUN2-201 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 1 hippie 73 222 13 13 1
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 25 169 19 19 0
OPA3-201 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 intact, hippie 3 44 0 0 2
OXCT1-201 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 Not Cancer Driver No 1 hippie 49 39 3 3 11
P3H1-202 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 Not Cancer Driver No 1 hippie 61 178 11 11 0
PCDHB15-201 PCDHB15 Q9Y5E8 Protocadherin beta-15 chr5 Not Cancer Driver No 1 intact, hippie 156 202 41 41 0
PDGFRA-201 PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 intact, hippie 213 173 36 36 2
PDIA6-201 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 hippie 41 82 8 8 0
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 32 49 7 7 0
PDYN-201 PDYN P01213 Proenkephalin-B chr20 Not Cancer Driver No 1 hippie 105 111 54 54 7
PFDN1-201 PFDN1 O60925 Prefoldin subunit 1 chr5 Not Cancer Driver No 1 hippie 6 42 3 3 0
PFDN5-202 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 1 hippie 16 3 0 0 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PNKP-201 PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 Not Cancer Driver No 1 hippie 46 177 21 21 4
POMC-203 POMC P01189 Pro-opiomelanocortin chr2 Not Cancer Driver No 1 hippie 28 200 23 23 0
PPP1R12A-203 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 hippie 76 822 63 63 0
PPP2CA-203 PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 32 12 1 1 7
PPP2R2A-202 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 36 68 6 6 0
PPP3CA-203 PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 1 hippie 63 140 24 24 7
PRM2-201 PRM2 P04554 Protamine-2 chr16 Not Cancer Driver No 1 hippie 7 102 7 7 0
PUS1-202 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 Not Cancer Driver No 1 hippie 39 157 10 10 1
RCC1L-201 RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 Not Cancer Driver No 1 hippie 13 87 6 6 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RPL10-202 RPL10 P27635 Large ribosomal subunit protein uL16 chrX Census, Compendium Yes 1 hippie 41 9 2 2 4
RPL36AL-201 RPL36AL Q969Q0 Ribosomal protein eL42-like chr14 Not Cancer Driver No 1 hippie 7 64 4 4 0
RPS25-202 RPS25 P62851 Small ribosomal subunit protein eS25 chr11 Not Cancer Driver No 1 hippie 12 60 7 7 0
SEPTIN1-201 SEPTIN1 Q8WYJ6 Septin-1 chr16 Not Cancer Driver No 1 intact 38 99 6 6 0
SETSIP-201 SETSIP P0DME0 Protein SETSIP chr1 Not Cancer Driver No 1 hippie 0 225 0 0 0
SLX4-201 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 201 1586 175 175 0
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
STK3-201 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie 48 241 22 22 0
TBL1X-208 TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX Not Cancer Driver No 1 hippie 63 181 23 23 0
TMEM184A-201 TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 1 intact, hippie 45 76 12 12 0
TNFSF12-201 TNFSF12 O43508 Tumor necrosis factor ligand superfamily member 12 chr17 Not Cancer Driver No 1 hippie 6 109 3 3 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie 2742 282 1364 1364 60
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 40 124 11 11 0
TRUB2-201 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie 28 73 6 6 0
TSN-201 TSN Q15631 Translin chr2 Not Cancer Driver No 1 hippie 21 0 0 0 0
UACA-201 UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 Not Cancer Driver No 1 hippie 110 867 67 67 0
UIMC1-212 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie 38 610 31 31 0
XPO5-201 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 85 64 6 6 0
ZNF707-201 ZNF707 Q96C28 Zinc finger protein 707 chr8 Not Cancer Driver No 2 intact, hippie 44 138 21 21 0
ZRANB1-201 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 65 158 16 16 0