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NTPCR-202 ,NTPCR ,Q9BSD7
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 48
  • Number of Interaction partner in hippie: 100
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AATK-201 AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 biogrid 82 916 59 59 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie 61 166 20 20 10
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 biogrid 233 577 79 79 12
AMBRA1-213 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 132 790 80 80 0
ANKRD55-201 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 72 340 48 48 0
ARAF-202 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 61 181 26 26 0
AUH-202 AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 29 0 0 1
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDK18-203 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 hippie 47 132 12 12 0
CDK20-201 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 1 hippie 29 32 1 1 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 216 145 9 9 130
CLEC4D-201 CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 52 18 3 3 0
CLEC4E-201 CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 42 5 2 2 0
COL1A1-201 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie, biogrid 36 1213 10 10 140
COL1A2-201 COL1A2 P08123 Collagen alpha-2(I) chain chr7 Not Cancer Driver No 1 hippie, biogrid 84 1160 50 50 81
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 98 168 18 18 3
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DLST-202 DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 33 192 23 23 1
DPP4-201 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 108 8 0 0 0
DUSP16-202 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie 55 273 26 26 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
EEF1AKMT3-201 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 16 34 1 1 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 2 hippie, biogrid 346 223 30 30 1
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EPHA4-201 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 biogrid 132 141 16 16 0
EPHA5-201 EPHA5 P54756 Ephrin type-A receptor 5 chr4 Not Cancer Driver No 1 biogrid 296 84 24 24 0
EPHA7-202 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 biogrid 226 71 10 10 0
EPHA8-201 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 biogrid 156 122 16 16 0
EPHB2-204 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 biogrid 149 120 11 11 7
EPHB6-212 EPHB6 O15197 Ephrin type-B receptor 6 chr7 Not Cancer Driver No 1 biogrid 190 246 39 39 0
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 biogrid 249 315 32 32 1
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FBXO7-201 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 49 243 24 24 1
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 biogrid 92 231 26 26 69
FGFR2-206 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 biogrid 193 229 34 34 57
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 biogrid 101 163 27 27 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 biogrid 203 259 33 33 14
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 289 1249 137 137 8
FOXO1-201 FOXO1 Q12778 Forkhead box protein O1 chr13 Census, Compendium Yes 1 hippie, biogrid 52 586 51 51 0
FURIN-201 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie, biogrid 72 283 30 30 0
GPR45-201 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 75 0 0 0 0
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
IFITM1-202 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
IFITM3-201 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 7 19 2 2 0
IFT140-203 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 Not Cancer Driver No 1 hippie 138 165 22 22 10
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
IGLC1-201 IGLC1 P0CG04 Immunoglobulin lambda constant 1 chr22 Not Cancer Driver No 1 hippie 0 0 0 0 0
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 5 301 4 4 21
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 30 72 7 7 0
INS-202 INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 7 5 1 1 19
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 biogrid 139 282 37 37 63
ISLR-201 ISLR O14498 Immunoglobulin superfamily containing leucine-rich repeat protein chr15 Not Cancer Driver No 1 hippie, biogrid 62 87 12 12 0
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MAD2L2-207 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 16 0 0 0 1
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MEPCE-201 MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 46 449 29 29 0
MERTK-201 MERTK Q12866 Tyrosine-protein kinase Mer chr2 Not Cancer Driver No 1 biogrid 134 161 25 25 3
MET-202 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 biogrid 161 62 10 10 16
MOSPD2-201 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 39 143 10 10 0
NBEAL2-205 NBEAL2 Q6ZNJ1 Neurobeachin-like protein 2 chr3 Not Cancer Driver No 1 hippie 222 515 47 47 8
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 biogrid 133 57 8 8 23
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 biogrid 214 56 15 15 3
NUP58-202 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 hippie 48 379 35 35 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 25 34 3 3 0
PAX3-204 PAX3 P23760 Paired box protein Pax-3 chr2 Census Yes 1 hippie, biogrid 95 391 80 80 25
PDGFRB-201 PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 biogrid 134 233 40 40 7
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 23 74 11 11 0
PHKG2-204 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 36 50 4 4 4
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PPEF1-204 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX Not Cancer Driver No 1 hippie 84 66 5 5 0
PPM1D-201 PPM1D O15297 Protein phosphatase 1D chr17 Census, Compendium Yes 1 hippie 32 370 17 17 0
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 54 124 13 13 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PTPN23-201 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 Not Cancer Driver No 1 hippie 96 800 51 51 2
RAMP3-201 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 99 232 31 31 3
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
ROS1-202 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 biogrid 356 197 45 45 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 45 98 7 7 1
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 20 117 12 12 0
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
RUVBL1-201 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 67 5 5 0
RUVBL2-206 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie, biogrid 52 100 11 11 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC38A1-201 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid symporter 1 chr12 Not Cancer Driver No 1 hippie 70 25 3 3 0
SMARCB1-213 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie 55 141 26 26 3
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
SSX2IP-201 SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 hippie 48 265 17 17 0
STAMBP-202 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie 42 143 15 15 6
STK38L-201 STK38L Q9Y2H1 Serine/threonine-protein kinase 38-like chr12 Not Cancer Driver No 1 hippie 31 86 6 6 0
TAF1-204 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1 hippie 278 1174 156 156 5
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 37 302 25 25 0
TFDP1-201 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 1 hippie 61 246 36 36 0
TGOLN2-201 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 39 401 33 33 0
TMPRSS2-201 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 47 25 3 3 0
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TOP3B-201 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 76 151 11 11 0
TPTE-204 TPTE P56180 Putative tyrosine-protein phosphatase TPTE chr21 Not Cancer Driver No 1 hippie 422 48 41 41 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRMT1L-201 TRMT1L Q7Z2T5 TRMT1-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 51 242 12 12 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 45 52 6 6 6
TUBG1-201 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 42 44 9 9 3
TYRO3-201 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 Not Cancer Driver No 1 biogrid 86 197 18 18 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 hippie 152 110 21 21 0
VWA8-203 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 Not Cancer Driver No 1 hippie, biogrid 153 384 24 24 0
WDR19-201 WDR19 Q8NEZ3 WD repeat-containing protein 19 chr4 Not Cancer Driver No 1 hippie 87 19 0 0 11
WDR35-202 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 Not Cancer Driver No 1 hippie 87 42 3 3 6
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
ZBTB38-201 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 95 649 49 49 0
ZNF24-201 ZNF24 P17028 Zinc finger protein 24 chr18 Not Cancer Driver No 1 hippie 25 189 13 13 0
ZNF746-201 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 68 437 43 43 0