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NUDC-201 ,NUDC ,Q9Y266
  • Number of Interaction partner in intact: 105
  • Number of Interaction partner in biogrid: 81
  • Number of Interaction partner in hippie: 244
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS-201 AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 intact, hippie 42 116 8 8 3
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ACD-212 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 Not Cancer Driver No 1 hippie 42 257 31 31 1
ACTR1A-201 ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 34 14 0 0 0
ACTR2-201 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 28 6 1 1 0
ADAM9-209 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 59 130 7 7 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 61 166 20 20 10
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
AMBRA1-213 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 intact, hippie 132 790 80 80 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ARMC8-210 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 42 7 0 0 0
ASCC3-204 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 biogrid 202 87 7 7 0
ATG5-204 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 33 25 6 6 1
ATN1-202 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact 111 1176 109 109 5
ATP6AP1-201 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 1 biogrid 52 0 0 0 4
ATP6V1G1-201 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 Not Cancer Driver No 1 biogrid 9 91 5 5 0
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 13 112 7 7 0
BBS1-201 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 intact, hippie 52 100 9 9 11
BBS7-201 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 Not Cancer Driver No 1 intact, hippie 69 56 4 4 4
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BOD1L1-201 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 biogrid 276 3030 276 276 0
BOP1-205 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 Not Cancer Driver No 1 hippie 15 304 14 14 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 3 intact, hippie, biogrid 57 45 3 3 0
CALCR-204 CALCR P30988 Calcitonin receptor chr7 Not Cancer Driver No 1 intact, hippie 124 22 6 6 0
CAMLG-201 CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 biogrid 23 158 13 13 0
CAST-207 CAST P20810 Calpastatin chr5 Not Cancer Driver No 1 hippie, biogrid 52 712 52 52 0
CCDC6-201 CCDC6 Q16204 Coiled-coil domain-containing protein 6 chr10 Census, Compendium Yes 1 hippie, biogrid 48 373 40 40 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDCA8-202 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 biogrid 18 171 10 10 0
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CFAP52-201 CFAP52 Q8N1V2 Cilia- and flagella-associated protein 52 chr17 Not Cancer Driver No 1 intact, hippie 85 4 0 0 1
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 216 145 9 9 130
CHAF1B-201 CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 Not Cancer Driver No 1 hippie 45 189 23 23 0
CHMP2A-201 CHMP2A O43633 Charged multivesicular body protein 2a chr19 Not Cancer Driver No 1 biogrid 17 161 12 12 0
CKAP5-210 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 biogrid 149 634 48 48 0
CMAS-201 CMAS Q8NFW8 N-acylneuraminate cytidylyltransferase chr12 Not Cancer Driver No 1 biogrid 29 89 3 3 0
COG3-201 COG3 Q96JB2 Conserved oligomeric Golgi complex subunit 3 chr13 Not Cancer Driver No 1 biogrid 50 110 4 4 0
COPS4-201 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 Not Cancer Driver No 1 biogrid 35 13 0 0 0
CORO1B-201 CORO1B Q9BR76 Coronin-1B chr11 Not Cancer Driver No 1 hippie 31 138 7 7 0
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 41 84 12 12 0
CORO2B-201 CORO2B Q9UQ03 Coronin-2B chr15 Not Cancer Driver No 1 hippie 69 37 5 5 0
CPSF1-212 CPSF1 Q10570 Cleavage and polyadenylation specificity factor subunit 1 chr8 Not Cancer Driver No 1 hippie 155 298 36 36 0
CRYAA-201 CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 intact, hippie 0 42 0 0 6
CSTB-201 CSTB P04080 Cystatin-B chr21 Not Cancer Driver No 1 hippie, biogrid 8 41 0 0 1
CTCFL-201 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 Not Cancer Driver No 1 hippie 99 269 40 40 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
DCAF11-204 DCAF11 Q8TEB1 DDB1- and CUL4-associated factor 11 chr14 Not Cancer Driver No 1 intact, hippie 65 149 18 18 0
DCAF4-202 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 1 intact, hippie 42 118 6 6 0
DCAF4L2-201 DCAF4L2 Q8NA75 DDB1- and CUL4-associated factor 4-like protein 2 chr8 Not Cancer Driver No 1 intact, hippie 223 25 13 13 0
DCPS-201 DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 32 55 5 5 1
DGKE-201 DGKE P52429 Diacylglycerol kinase epsilon chr17 Not Cancer Driver No 1 intact, hippie, biogrid 61 34 3 3 3
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 55 17 0 0 10
DLG4-202 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 1 intact 74 233 34 34 0
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie 61 378 23 23 0
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 29 154 13 13 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 34 174 18 18 0
DNAJB1-201 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 4 intact, hippie, biogrid 26 196 20 20 0
DNAJB4-201 DNAJB4 Q9UDY4 DnaJ homolog subfamily B member 4 chr1 Not Cancer Driver No 2 intact, hippie 31 160 16 16 0
DUX4-203 DUX4 Q9UBX2 Double homeobox protein 4 chr4 Not Cancer Driver No 1 hippie 0 407 0 0 0
DYNC1I1-201 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 125 256 51 51 0
DYNC1I2-202 DYNC1I2 Q13409 Cytoplasmic dynein 1 intermediate chain 2 chr2 Not Cancer Driver No 1 hippie, biogrid 57 300 30 30 1
DYNC1LI1-201 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 Not Cancer Driver No 1 hippie 30 208 13 13 0
DYNC2I1-202 DYNC2I1 Q8WVS4 Cytoplasmic dynein 2 intermediate chain 1 chr7 Not Cancer Driver No 3 intact 92 525 48 48 1
DYNLRB1-202 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 Not Cancer Driver No 1 hippie 19 19 4 4 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EIF1B-201 EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie 10 6 0 0 0
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 biogrid 49 179 9 9 21
EIF3C-201 EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 biogrid 3 392 1 1 0
EIF6-203 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 22 17 2 2 0
EIPR1-201 EIPR1 Q53HC9 EARP and GARP complex-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 45 70 5 5 0
ELF3-203 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 intact, hippie 84 147 31 31 0
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 biogrid 38 29 2 2 0
EML1-201 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 113 205 25 25 2
EML4-201 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 Census, Compendium Yes 1 hippie 78 387 33 33 0
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 37 21 2 2 0
ENST00000419755 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 intact, hippie 52 132 7 7 11
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 249 315 32 32 1
ERH-203 ERH P84090 Enhancer of rudimentary homolog chr14 Not Cancer Driver No 1 biogrid 5 11 0 0 0
ETF1-201 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 hippie 36 28 5 5 0
EVC2-202 EVC2 Q86UK5 Limbin chr4 Not Cancer Driver No 1 intact, hippie 184 340 56 56 2
EXOSC4-201 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 biogrid 26 23 0 0 0
EXOSC9-201 EXOSC9 Q06265 Exosome complex component RRP45 chr4 Not Cancer Driver No 1 biogrid 30 155 11 11 1
EZH2-203 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 74 284 32 32 11
FAF1-201 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 54 241 23 23 0
FAM120C-202 FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 127 511 66 66 0
FBXL7-202 FBXL7 Q9UJT9 F-box/LRR-repeat protein 7 chr5 Not Cancer Driver No 1 intact, hippie 178 117 26 26 0
FBXO24-201 FBXO24 O75426 F-box only protein 24 chr7 Not Cancer Driver No 1 intact, hippie 88 55 9 9 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 41 20 2 2 6
FBXW2-203 FBXW2 Q9UKT8 F-box/WD repeat-containing protein 2 chr9 Not Cancer Driver No 1 intact, hippie 35 0 0 0 0
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie, biogrid 289 232 15 15 17
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 47 150 15 15 0
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 55 352 38 38 0
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie, biogrid 36 24 3 3 0
GBF1-223 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 161 670 62 62 0
GIPC1-203 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 Not Cancer Driver No 1 hippie 44 140 16 16 0
GNB2-201 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 intact 30 21 0 0 5
GNB4-201 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 intact, hippie 35 28 0 0 2
GNB5-201 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 Not Cancer Driver No 1 hippie 45 16 0 0 1
GOLT1B-201 GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 biogrid 14 0 0 0 0
GRK6-201 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 43 68 8 8 0
GTF2E1-201 GTF2E1 P29083 General transcription factor IIE subunit 1 chr3 Not Cancer Driver No 1 biogrid 48 265 31 31 0
GTF2H1-201 GTF2H1 P32780 General transcription factor IIH subunit 1 chr11 Not Cancer Driver No 1 hippie 36 139 9 9 0
GTF3C5-202 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 Not Cancer Driver No 1 intact 54 157 17 17 0
HCFC2-201 HCFC2 Q9Y5Z7 Host cell factor 2 chr12 Not Cancer Driver No 1 hippie 68 279 28 28 0
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 145 751 95 95 3
HDAC5-213 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 93 720 61 61 0
HDGF-201 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 25 203 21 21 0
HLA-B-249 HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 49 169 18 18 0
HLA-C-201 HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie 36 175 14 14 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact, hippie 44 258 15 15 0
HUS1-201 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 19 17 1 1 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IFT122-203 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie 108 54 5 5 5
IFT140-203 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 Not Cancer Driver No 1 intact, hippie 138 165 22 22 10
IFT172-201 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 Not Cancer Driver No 2 intact, hippie 154 96 4 4 8
IFT80-201 IFT80 Q9P2H3 Intraflagellar transport protein 80 homolog chr3 Not Cancer Driver No 2 intact, hippie 84 21 1 1 2
IGBP1-202 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 32 194 18 18 0
INS-202 INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 7 5 1 1 19
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KATNB1-201 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 Not Cancer Driver No 1 intact, hippie 55 183 20 20 3
KATNIP-201 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 182 990 108 108 0
KDM6B-202 KDM6B O15054 Lysine-specific demethylase 6B chr17 Not Cancer Driver No 1 hippie 151 1288 116 116 2
KIF21B-203 KIF21B O75037 Kinesin-like protein KIF21B chr1 Not Cancer Driver No 1 intact, hippie 242 781 124 124 0
KLF16-201 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 12 206 7 7 0
KLHDC1-201 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 Not Cancer Driver No 1 intact, hippie 27 37 5 5 0
KLHDC8A-201 KLHDC8A Q8IYD2 Kelch domain-containing protein 8A chr1 Not Cancer Driver No 1 intact, hippie 46 3 2 2 0
KLHL26-201 KLHL26 Q53HC5 Kelch-like protein 26 chr19 Not Cancer Driver No 1 intact, hippie 61 56 4 4 0
KLHL34-201 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 intact, hippie 79 77 12 12 0
KLHL38-202 KLHL38 Q2WGJ6 Kelch-like protein 38 chr8 Not Cancer Driver No 1 intact, hippie 91 3 2 2 0
KLHL6-201 KLHL6 Q8WZ60 Kelch-like protein 6 chr3 Compendium Yes 1 intact, hippie 99 25 5 5 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 intact, hippie 39 353 28 28 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 76 95 12 12 1
LEO1-201 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 57 611 53 53 0
LLGL1-201 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie 78 266 9 9 0
LLGL2-203 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 hippie 98 266 15 15 0
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
LRWD1-201 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 Not Cancer Driver No 1 intact, hippie 46 133 9 9 0
LXN-201 LXN Q9BS40 Latexin chr3 Not Cancer Driver No 1 hippie 11 92 5 5 0
MAD1L1-201 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie, biogrid 82 526 55 55 0
MAEL-202 MAEL Q96JY0 Protein maelstrom homolog chr1 Not Cancer Driver No 1 intact, hippie 95 116 26 26 0
MAGEL2-201 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 Not Cancer Driver No 1 hippie 157 1010 104 104 0
MAP3K3-202 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 48 356 27 27 0
MAP4K1-210 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 91 277 37 37 0
MAPK13-201 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 34 50 11 11 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MBTPS2-202 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 41 16 3 3 9
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
MFN2-201 MFN2 O95140 Mitofusin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 60 82 7 7 19
MINK1-202 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 86 742 42 42 0
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 1 intact, hippie 59 153 18 18 2
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 intact, hippie 24 45 3 3 0
MOS-201 MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 1 intact, hippie 69 16 2 2 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MTCH2-201 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 0
MTMR7-201 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 Not Cancer Driver No 1 hippie 75 161 18 18 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NAGK-201 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 Not Cancer Driver No 1 hippie 35 5 1 1 0
NAT10-201 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 intact, hippie 75 142 9 9 0
NCBP1-202 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 biogrid 66 89 7 7 0
NEK8-201 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 intact, hippie 75 167 29 29 3
NFATC2-202 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 144 726 124 124 0
NHLRC1-201 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 Not Cancer Driver No 1 intact, hippie 52 18 3 3 22
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
NPHP4-201 NPHP4 O75161 Nephrocystin-4 chr1 Not Cancer Driver No 1 intact, hippie 137 474 44 44 17
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUBP2-201 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 28 14 1 1 0
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 49 38 2 2 0
NUP43-201 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 1 biogrid 40 104 7 7 0
NUP85-201 NUP85 Q9BW27 Nuclear pore complex protein Nup85 chr17 Not Cancer Driver No 1 hippie 45 32 1 1 2
NWD1-205 NWD1 Q149M9 NACHT domain- and WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 219 89 10 10 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OFD1-201 OFD1 O75665 Centriole and centriolar satellite protein OFD1 chrX Not Cancer Driver No 1 hippie 77 476 25 25 5
OGT-202 OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 111 90 9 9 2
OPA1-204 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 biogrid 86 131 14 14 58
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
OTUD4-201 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 94 789 74 74 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
PAFAH1B1-202 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 2 hippie, biogrid 37 83 11 11 7
PAK2-201 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 61 242 31 31 1
PAPOLA-201 PAPOLA P51003 Poly(A) polymerase alpha chr14 Not Cancer Driver No 1 hippie 70 293 26 26 0
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PEX7-201 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 Not Cancer Driver No 1 intact, hippie 29 0 0 0 2
PGD-201 PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 biogrid 50 19 2 2 0
PHLPP1-201 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 1 intact, hippie 104 746 21 21 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PIWIL1-201 PIWIL1 Q96J94 Piwi-like protein 1 chr12 Not Cancer Driver No 1 intact, hippie 143 172 25 25 3
PIWIL4-201 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 Not Cancer Driver No 1 intact, hippie 78 89 9 9 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 129 925 106 106 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
POC1A-201 POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 3 hippie, biogrid 33 88 6 6 1
POC1B-201 POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 4 intact, hippie, biogrid 44 86 6 6 1
POLD1-201 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 118 210 17 17 2
POLR2K-201 POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 biogrid 8 11 1 1 0
POT1-201 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 98 31 5 5 9
PPME1-201 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 28 146 8 8 0
PPP5C-201 PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 58 73 10 10 0
PPP6C-201 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 hippie 51 0 0 0 0
PPP6R2-201 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 Not Cancer Driver No 1 hippie, biogrid 76 496 48 48 0
PRDM1-203 PRDM1 O75626 PR domain zinc finger protein 1 chr6 Census, Compendium Yes 1 intact 122 339 56 56 0
PREB-201 PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 Not Cancer Driver No 1 hippie 36 91 7 7 0
PRKAB1-201 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 21 125 11 11 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PRPF19-201 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 intact, hippie 43 110 12 12 0
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie, biogrid 202 226 24 24 6
PSMB6-201 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 biogrid 16 22 1 1 0
PUF60-208 PUF60 Q9UHX1 Poly(U)-binding-splicing factor PUF60 chr8 Not Cancer Driver No 1 hippie 38 214 12 12 1
RABGGTA-201 RABGGTA Q92696 Geranylgeranyl transferase type-2 subunit alpha chr14 Not Cancer Driver No 1 intact 57 37 1 1 0
RAG1-201 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 Not Cancer Driver No 1 intact, hippie 161 209 34 34 35
RBM39-201 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 53 228 16 16 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 64 420 31 31 0
RND2-202 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 17 54 4 4 0
RPGR-201 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX Not Cancer Driver No 1 intact, hippie 59 643 29 29 20
RPS17-209 RPS17 P08708 Small ribosomal subunit protein eS17 chr15 Not Cancer Driver No 1 intact, hippie 0 40 0 0 0
RPS6KB2-201 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 34 195 8 8 0
RRP9-201 RRP9 O43818 U3 small nucleolar RNA-interacting protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 41 146 6 6 0
SCAP-201 SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 Not Cancer Driver No 1 intact, hippie 108 331 27 27 0
SCYL1-201 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 biogrid 58 312 23 23 0
SIM2-201 SIM2 Q14190 Single-minded homolog 2 chr21 Not Cancer Driver No 1 intact, hippie 48 262 9 9 0
SLC35A1-201 SLC35A1 P78382 CMP-sialic acid transporter chr6 Not Cancer Driver No 1 biogrid 15 0 0 0 3
SLC39A9-202 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 1 biogrid 25 44 1 1 0
SNW1-201 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 59 487 53 53 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 14 94 9 9 57
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
SUZ12-201 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 55 483 32 32 3
SWSAP1-201 SWSAP1 Q6NVH7 ATPase SWSAP1 chr19 Not Cancer Driver No 1 intact 15 106 7 7 0
SYMPK-201 SYMPK Q92797 Symplekin chr19 Not Cancer Driver No 1 hippie 126 399 34 34 0
TBL1Y-203 TBL1Y Q9BQ87 F-box-like/WD repeat-containing protein TBL1Y chrY Not Cancer Driver No 1 intact, hippie 26 138 6 6 0
TBL3-205 TBL3 Q12788 Transducin beta-like protein 3 chr16 Not Cancer Driver No 1 hippie 64 48 4 4 0
TFDP3-201 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX Not Cancer Driver No 1 intact, hippie 65 186 33 33 0
THOC6-202 THOC6 Q86W42 THO complex subunit 6 homolog chr16 Not Cancer Driver No 1 intact, hippie 34 16 3 3 1
TIMM9-202 TIMM9 Q9Y5J7 Mitochondrial import inner membrane translocase subunit Tim9 chr14 Not Cancer Driver No 1 hippie, biogrid 5 8 0 0 0
TIMP2-201 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 Not Cancer Driver No 1 intact, hippie 25 6 1 1 0
TINF2-201 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 hippie 29 190 13 13 3
TLE2-201 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 1 hippie 62 283 23 23 0
TLE6-201 TLE6 Q9H808 Transducin-like enhancer protein 6 chr19 Not Cancer Driver No 1 intact, hippie 67 228 27 27 1
TLN1-201 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie 211 1110 90 90 0
TNFRSF10D-201 TNFRSF10D Q9UBN6 Tumor necrosis factor receptor superfamily member 10D chr8 Not Cancer Driver No 1 hippie 36 200 18 18 0
TNIK-204 TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 126 782 86 86 0
TP53BP1-201 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 159 1638 131 131 0
TRIM17-204 TRIM17 Q9Y577 E3 ubiquitin-protein ligase TRIM17 chr1 Not Cancer Driver No 1 hippie 53 129 16 16 0
TRIM24-201 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie, biogrid 90 537 45 45 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRMT1-202 TRMT1 Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase chr19 Not Cancer Driver No 1 hippie, biogrid 68 200 21 21 0
TSSK1B-201 TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 75 117 29 29 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie, biogrid 45 52 6 6 6
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 50 39 2 2 4
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 29 63 5 5 5
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 25 32 4 4 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UGP2-201 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 Not Cancer Driver No 1 hippie 41 55 5 5 1
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie 25 36 4 4 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 85 117 15 15 84
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VPS26A-201 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 hippie 21 45 3 3 0
VPS29-206 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie 15 0 0 0 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 55 99 7 7 1
WDFY2-201 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 38 20 2 2 0
WDR31-202 WDR31 Q8NA23 WD repeat-containing protein 31 chr9 Not Cancer Driver No 1 intact, hippie 41 5 1 1 0
WDR35-202 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 Not Cancer Driver No 2 intact, hippie 87 42 3 3 6
WDR36-203 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 1 intact, hippie 82 89 5 5 2
WDR7-201 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 biogrid 164 292 28 28 0
WDR81-202 WDR81 Q562E7 WD repeat-containing protein 81 chr17 Not Cancer Driver No 1 intact, hippie 120 725 40 40 1
WDR88-201 WDR88 Q6ZMY6 WD repeat-containing protein 88 chr19 Not Cancer Driver No 1 hippie 62 73 10 10 0
WDR90-201 WDR90 Q96KV7 WD repeat-containing protein 90 chr16 Not Cancer Driver No 1 intact, hippie 127 252 23 23 0
WDR91-201 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 Not Cancer Driver No 1 intact, hippie 72 207 24 24 0
WDTC1-201 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 Not Cancer Driver No 1 intact, hippie 66 154 19 19 0
WIPI2-201 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 38 68 5 5 1
WRAP73-201 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 34 5 0 0 0
WSB2-201 WSB2 Q9NYS7 WD repeat and SOCS box-containing protein 2 chr12 Not Cancer Driver No 1 hippie 38 37 7 7 0
XRN2-201 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 biogrid 91 428 48 48 0
YAF2-203 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie 22 169 22 22 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
YTHDC1-201 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 biogrid 52 597 36 36 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZYX-201 ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 49 385 29 29 0