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OMA1-201 ,OMA1 ,Q96E52
  • Number of Interaction partner in intact: 75
  • Number of Interaction partner in biogrid: 53
  • Number of Interaction partner in hippie: 132
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB8-201 ABCB8 Q9NUT2 Mitochondrial potassium channel ATP-binding subunit chr7 Not Cancer Driver No 1 hippie 88 55 5 5 0
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 54 28 2 2 12
ADCK2-201 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 intact, hippie 46 9 1 1 0
ADCY8-201 ADCY8 P40145 Adenylate cyclase type 8 chr8 Not Cancer Driver No 1 hippie, biogrid 358 215 31 31 0
ADCY9-201 ADCY9 O60503 Adenylate cyclase type 9 chr16 Not Cancer Driver No 1 hippie, biogrid 137 272 32 32 0
AFG3L2-201 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 intact, hippie 38 162 5 5 17
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 61 166 20 20 10
AK2-214 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 17 76 8 8 2
AMIGO3-201 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 Not Cancer Driver No 2 hippie, biogrid 51 60 5 5 0
APOO-201 APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 2 hippie, biogrid 21 23 4 4 0
APOOL-201 APOOL Q6UXV4 MICOS complex subunit MIC27 chrX Not Cancer Driver No 1 intact, hippie 22 91 7 7 0
ATAD3A-202 ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 Not Cancer Driver No 1 intact, hippie 49 275 16 16 2
ATAD3B-206 ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 63 245 17 17 0
ATP11A-202 ATP11A P98196 Phospholipid-transporting ATPase IH chr13 Not Cancer Driver No 1 hippie, biogrid 115 77 13 13 1
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 76 115 14 14 6
ATP1B1-201 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 Not Cancer Driver No 1 hippie, biogrid 32 55 6 6 0
ATPAF1-211 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 intact, hippie 24 47 4 4 0
B4GALT5-201 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 Not Cancer Driver No 1 hippie, biogrid 32 20 0 0 0
BZW2-201 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 31 59 6 6 0
C5AR1-201 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 52 0 0 0 0
CBR1-201 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 Not Cancer Driver No 1 hippie 20 64 9 9 0
CCDC142-202 CCDC142 Q17RM4 Coiled-coil domain-containing protein 142 chr2 Not Cancer Driver No 1 hippie, biogrid 45 165 14 14 0
CHCHD3-201 CHCHD3 Q9NX63 MICOS complex subunit MIC19 chr7 Not Cancer Driver No 1 intact, hippie 21 143 14 14 0
CHCHD6-201 CHCHD6 Q9BRQ6 MICOS complex subunit MIC25 chr3 Not Cancer Driver No 1 intact, hippie 22 196 21 21 0
CKMT1A-202 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 Not Cancer Driver No 1 hippie 17 77 0 0 0
CKMT1B-207 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 Not Cancer Driver No 1 hippie 19 77 1 1 0
CLPB-201 CLPB Q9H078 Mitochondrial disaggregase chr11 Not Cancer Driver No 1 intact, hippie 54 224 22 22 20
CNPPD1-201 CNPPD1 Q9BV87 Protein CNPPD1 chr2 Not Cancer Driver No 2 hippie, biogrid 37 12 0 0 0
COA3-201 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 3 57 2 2 0
COA7-201 COA7 Q96BR5 Cytochrome c oxidase assembly factor 7 chr1 Not Cancer Driver No 1 intact, hippie 19 40 5 5 2
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie 33 0 0 0 2
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie 13 5 1 1 1
COX5A-201 COX5A P20674 Cytochrome c oxidase subunit 5A, mitochondrial chr15 Not Cancer Driver No 1 hippie 17 14 4 4 1
COX5B-201 COX5B P10606 Cytochrome c oxidase subunit 5B, mitochondrial chr2 Not Cancer Driver No 1 hippie 13 58 6 6 0
COX6C-205 COX6C P09669 Cytochrome c oxidase subunit 6C chr8 Census Yes 1 intact, hippie 9 0 0 0 0
CPOX-204 CPOX P36551 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 33 128 5 5 16
CYC1-201 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 intact, hippie 44 35 2 2 2
CYCS-201 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 intact, hippie 10 20 2 2 1
DNAH17-201 DNAH17 Q9UFH2 Dynein axonemal heavy chain 17 chr17 Not Cancer Driver No 1 hippie, biogrid 516 176 19 19 3
DNAJC11-202 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 intact, hippie 45 123 8 8 0
ECSIT-202 ECSIT Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial chr19 Not Cancer Driver No 1 hippie 50 146 25 25 0
EDEM1-201 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 44 141 5 5 0
EDEM2-202 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 54 55 3 3 0
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 77 61 4 4 2
ENDOG-201 ENDOG Q14249 Endonuclease G, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 7 61 0 0 0
ERP44-201 ERP44 Q9BS26 Endoplasmic reticulum resident protein 44 chr9 Not Cancer Driver No 1 intact, hippie 33 43 3 3 0
FAM136A-201 FAM136A Q96C01 Protein FAM136A chr2 Not Cancer Driver No 1 intact, hippie 11 13 1 1 0
FAM162A-203 FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 intact, hippie 10 53 4 4 0
FAM8A1-201 FAM8A1 Q9UBU6 Protein FAM8A1 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 23 196 11 11 0
FANCC-201 FANCC Q00597 Fanconi anemia group C protein chr9 Census, Compendium Yes 1 hippie, biogrid 38 13 0 0 3
GCGR-201 GCGR P47871 Glucagon receptor chr17 Not Cancer Driver No 1 hippie, biogrid 12 56 2 2 4
GPD2-207 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 66 67 5 5 0
GXYLT1-202 GXYLT1 Q4G148 Glucoside xylosyltransferase 1 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 37 7 0 0 0
HAX1-201 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 intact, hippie 30 219 23 23 2
HCCS-202 HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 1 hippie 46 117 24 24 1
IARS2-201 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 95 145 17 17 0
IFNA8-201 IFNA8 P32881 Interferon alpha-8 chr9 Not Cancer Driver No 3 hippie, biogrid 33 0 0 0 0
IFNGR2-201 IFNGR2 P38484 Interferon gamma receptor 2 chr21 Not Cancer Driver No 1 hippie, biogrid 22 18 1 1 5
IMMP1L-209 IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 15 3 0 0 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
IMMT-204 IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 75 402 39 39 0
IRGC-201 IRGC Q6NXR0 Interferon-inducible GTPase 5 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 89 159 33 33 0
KCNK18-201 KCNK18 Q7Z418 Potassium channel subfamily K member 18 chr10 Not Cancer Driver No 1 hippie, biogrid 79 7 0 0 0
KLRC1-202 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 Not Cancer Driver No 1 hippie, biogrid 33 50 6 6 0
KRT81-201 KRT81 Q14533 Keratin, type II cuticular Hb1 chr12 Not Cancer Driver No 1 hippie, biogrid 34 18 3 3 3
KRT86-202 KRT86 O43790 Keratin, type II cuticular Hb6 chr12 Not Cancer Driver No 1 biogrid 39 28 1 1 5
KRTAP19-7-201 KRTAP19-7 Q3SYF9 Keratin-associated protein 19-7 chr21 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
KRTAP6-1-201 KRTAP6-1 Q3LI64 Keratin-associated protein 6-1 chr21 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 0
LACTB-201 LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 29 123 2 2 0
LETM1-201 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 Not Cancer Driver No 1 hippie 52 289 19 19 4
MCM3-205 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 1 intact, hippie 58 310 28 28 0
MICU1-201 MICU1 Q9BPX6 Calcium uptake protein 1, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 35 97 9 9 0
MICU2-201 MICU2 Q8IYU8 Calcium uptake protein 2, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie 35 10 1 1 0
MIX23-201 MIX23 Q4VC31 Protein MIX23 chr3 Not Cancer Driver No 1 intact 12 15 0 0 0
MT-ND4-201 MT-ND4 P03905 NADH-ubiquinone oxidoreductase chain 4 chrM Not Cancer Driver No 1 intact 0 0 0 0 3
MTX1-202 MTX1 Q13505 Metaxin-1 chr1 Not Cancer Driver No 1 intact, hippie 14 221 5 5 0
MTX2-201 MTX2 O75431 Metaxin-2 chr2 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
NCR3LG1-201 NCR3LG1 Q68D85 Natural cytotoxicity triggering receptor 3 ligand 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 2 70 1 1 0
NDUFA12-201 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 14 31 5 5 0
NDUFA8-201 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 intact, hippie 20 33 1 1 2
NDUFAF4-201 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 intact, hippie 8 47 3 3 2
NDUFB10-201 NDUFB10 O96000 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 chr16 Not Cancer Driver No 1 intact, hippie 16 34 0 0 1
NDUFB11-202 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 20 51 6 6 1
NDUFB5-201 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 23 9 1 1 0
NDUFB9-201 NDUFB9 Q9Y6M9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 chr8 Not Cancer Driver No 1 hippie 20 34 4 4 1
NDUFS1-201 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 58 40 3 3 2
NDUFS2-224 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 44 51 4 4 4
NDUFV2-201 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie 30 70 10 10 0
NDUFV3-201 NDUFV3 P56181 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial chr21 Not Cancer Driver No 1 hippie 4 95 4 4 0
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 25 169 19 19 0
OCIAD2-205 OCIAD2 Q56VL3 OCIA domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 19 27 5 5 0
OPA1-204 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie 86 131 14 14 58
OPRL1-201 OPRL1 P41146 Nociceptin receptor chr20 Not Cancer Driver No 1 hippie, biogrid 70 0 0 0 0
P2RX1-201 P2RX1 P51575 P2X purinoceptor 1 chr17 Not Cancer Driver No 2 hippie, biogrid 42 14 0 0 0
PARL-202 PARL Q9H300 Presenilin-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 38 28 5 5 0
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 606 60 60 0
PLGRKT-201 PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 11 0 0 0 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RNH1-201 RNH1 P13489 Ribonuclease inhibitor chr11 Not Cancer Driver No 1 intact, hippie 32 0 0 0 0
SAAL1-202 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 1 hippie, biogrid 36 75 8 8 0
SAMM50-201 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 intact, hippie 32 35 0 0 0
SCN3B-201 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 45 16 2 2 3
SCO1-201 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 27 79 6 6 1
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 21 29 0 0 0
SIDT2-202 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 75 23 3 3 0
SIL1-202 SIL1 Q9H173 Nucleotide exchange factor SIL1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 32 126 10 10 0
SLC15A1-202 SLC15A1 P46059 Solute carrier family 15 member 1 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 83 26 1 1 0
SLC25A12-202 SLC25A12 O75746 Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 77 21 4 4 2
SLC25A24-203 SLC25A24 Q6NUK1 Mitochondrial adenyl nucleotide antiporter SLC25A24 chr1 Not Cancer Driver No 1 intact, hippie 28 21 1 1 1
SLC25A25-201 SLC25A25 Q6KCM7 Mitochondrial adenyl nucleotide antiporter SLC25A25 chr9 Not Cancer Driver No 1 intact 25 5 1 1 0
SLC25A51-201 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 19 21 0 0 0
SLC26A4-207 SLC26A4 O43511 Pendrin chr7 Not Cancer Driver No 1 hippie, biogrid 90 10 0 0 73
SLC30A9-201 SLC30A9 Q6PML9 Proton-coupled zinc antiporter SLC30A9, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 55 61 5 5 0
SLC39A4-202 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 58 116 9 9 9
SLC4A8-203 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 127 276 32 32 0
SLC5A4-201 SLC5A4 Q9NY91 Probable glucose sensor protein SLC5A4 chr22 Not Cancer Driver No 1 hippie, biogrid 83 50 5 5 0
SMIM12-206 SMIM12 Q96EX1 Small integral membrane protein 12 chr1 Not Cancer Driver No 1 intact, hippie 3 28 1 1 0
SYCE3-202 SYCE3 A1L190 Synaptonemal complex central element protein 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 3 41 1 1 0
TBC1D25-201 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX Not Cancer Driver No 1 intact, hippie, biogrid 83 258 25 25 0
TIMM13-201 TIMM13 Q9Y5L4 Mitochondrial import inner membrane translocase subunit Tim13 chr19 Not Cancer Driver No 1 intact, hippie 6 20 2 2 0
TIMM8A-201 TIMM8A O60220 Mitochondrial import inner membrane translocase subunit Tim8 A chrX Not Cancer Driver No 1 hippie 13 22 1 1 1
TIMMDC1-208 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 1 hippie 37 51 4 4 0
TMEM126B-201 TMEM126B Q8IUX1 Complex I assembly factor TMEM126B, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 14 18 2 2 1
TMEM186-201 TMEM186 Q96B77 Transmembrane protein 186 chr16 Not Cancer Driver No 1 hippie 18 2 0 0 0
TMEM9-201 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 Not Cancer Driver No 1 hippie, biogrid 18 24 1 1 0
TOMM70-201 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 Not Cancer Driver No 1 intact, hippie 47 141 7 7 0
TOR3A-203 TOR3A Q9H497 Torsin-3A chr1 Not Cancer Driver No 3 intact, hippie, biogrid 38 16 0 0 0
TPP1-201 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 56 92 7 7 34
TTC19-201 TTC19 Q6DKK2 Tetratricopeptide repeat protein 19, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 20 76 1 1 0
TTYH1-202 TTYH1 Q9H313 Protein tweety homolog 1 chr19 Not Cancer Driver No 1 hippie, biogrid 40 21 1 1 0
TUBGCP3-201 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie, biogrid 70 157 12 12 0
UGGT1-201 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 intact, hippie 113 162 14 14 0
USP30-201 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 Not Cancer Driver No 1 intact, hippie 53 136 22 22 0
UST-201 UST Q9Y2C2 Uronyl 2-sulfotransferase chr6 Not Cancer Driver No 1 hippie, biogrid 49 57 6 6 0
VAC14-201 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 76 117 17 17 3
YME1L1-201 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 intact, hippie 80 136 10 10 1