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OTUD7B-202 ,OTUD7B ,Q6GQQ9
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 7
  • Number of Interaction partner in hippie: 101
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M-201 A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 203 144 20 20 0
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 54 28 2 2 12
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 hippie 94 87 10 10 1
ALB-201 ALB P02768 Albumin chr4 Compendium Yes 1 intact, hippie 127 6 0 0 2
ANO7-201 ANO7 Q6IWH7 Anoctamin-7 chr2 Not Cancer Driver No 1 hippie 111 150 23 23 0
ATXN1-202 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 intact, hippie 111 608 91 91 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 25 180 17 17 0
BAG6-237 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 intact, hippie 73 856 59 59 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 36 190 15 15 0
CASP6-201 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 19 24 4 4 0
CASP8-218 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 116 106 11 11 1
CCDC50-202 CCDC50 Q8IVM0 Coiled-coil domain-containing protein 50 chr3 Not Cancer Driver No 1 hippie 41 282 33 33 0
CCNB1-201 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 Not Cancer Driver No 1 hippie 30 146 10 10 0
CDC20-201 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 36 198 12 12 0
CDIP1-209 CDIP1 Q9H305 Cell death-inducing p53-target protein 1 chr16 Not Cancer Driver No 1 hippie 7 119 6 6 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
DAZAP2-201 DAZAP2 Q15038 DAZ-associated protein 2 chr12 Not Cancer Driver No 1 hippie 11 68 6 6 0
DBH-202 DBH P09172 Dopamine beta-hydroxylase chr9 Not Cancer Driver No 1 intact, hippie 102 72 18 18 3
DCTN1-226 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 1 intact, hippie 129 818 84 84 9
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 intact 61 378 23 23 0
DNALI1-206 DNALI1 O14645 Axonemal dynein light intermediate polypeptide 1 chr1 Not Cancer Driver No 1 intact, hippie 18 177 10 10 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF2S3-201 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX Not Cancer Driver No 1 hippie 41 51 5 5 1
EPAS1-201 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 hippie 109 451 54 54 4
EPM2AIP1-201 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 Not Cancer Driver No 1 hippie 40 22 0 0 0
ERN1-201 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 Not Cancer Driver No 1 hippie 91 251 17 17 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
FAM168A-201 FAM168A Q92567 Protein FAM168A chr11 Not Cancer Driver No 1 hippie, biogrid 15 141 10 10 0
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 134 241 18 18 32
FKBP1A-204 FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 Not Cancer Driver No 1 intact 11 39 6 6 0
FOXM1-202 FOXM1 Q08050 Forkhead box protein M1 chr12 Not Cancer Driver No 1 hippie 73 605 57 57 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GFAP-214 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 45 290 27 27 41
GRIN2C-201 GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 78 278 3 3 0
GSN-204 GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 51 318 18 18 1
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 3 hippie, biogrid 24 78 5 5 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HSFY1-201 HSFY2 Q96LI6 Heat shock transcription factor, Y-linked chrY Not Cancer Driver No 1 hippie 0 158 0 0 0
HSFY2-201 HSFY2 Q96LI6 Heat shock transcription factor, Y-linked chrY Not Cancer Driver No 1 hippie 0 158 0 0 0
HSPA2-201 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 intact, hippie 68 286 30 30 0
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 19
HTRA2-201 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 33 127 7 7 2
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 143 265 30 30 6
JPH3-201 JPH3 Q8WXH2 Junctophilin-3 chr16 Not Cancer Driver No 1 hippie 105 539 75 75 0
KDM1A-201 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 48 291 21 21 3
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 187 634 82 82 1
KLF11-201 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 45 310 32 32 2
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 29 55 4 4 1
LGR4-201 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 73 16 2 2 0
MAGI1-202 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 173 1181 140 140 0
MAP3K14-201 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 hippie 0 543 0 0 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MAVS-202 MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 55 415 44 44 0
MECP2-201 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 intact, hippie 44 482 43 43 32
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie 24 45 3 3 0
MSH3-201 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 Not Cancer Driver No 1 hippie, biogrid 65 218 11 11 0
MTSS2-201 MTSS2 Q765P7 Protein MTSS 2 chr16 Not Cancer Driver No 1 hippie 53 584 41 41 1
N4BP1-201 N4BP1 O75113 NEDD4-binding protein 1 chr16 Not Cancer Driver No 1 hippie 71 433 38 38 0
NDUFV2-201 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie 30 70 10 10 0
NF2-202 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 49 252 18 18 16
NUP155-201 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 128 221 17 17 1
NUP58-202 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 intact, hippie 48 379 35 35 0
OTUD7A-204 OTUD7A Q8TE49 OTU domain-containing protein 7A chr15 Not Cancer Driver No 2 hippie, biogrid 103 592 55 55 0
OTULIN-201 OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 Not Cancer Driver No 1 hippie 32 97 3 3 8
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie 8 30 0 0 6
PHYH-201 PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 34 41 2 2 14
PIK3C3-201 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 Not Cancer Driver No 1 hippie 101 192 28 28 0
PIK3R3-201 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 42 149 17 17 0
PMP22-201 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 intact 17 0 0 0 32
PPP1R32-201 PPP1R32 Q7Z5V6 Protein phosphatase 1 regulatory subunit 32 chr11 Not Cancer Driver No 1 hippie 61 383 49 49 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PRPF40A-213 PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 intact, hippie 39 695 29 29 0
PRPS1-204 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie 28 0 0 0 16
PSMB1-201 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie 20 15 2 2 0
RAN-212 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 18 14 0 0 0
RNF11-201 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 11 78 6 6 0
SNCA-205 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 15 107 10 10 5
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie 14 94 9 9 57
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 32 312 32 32 0
SPART-202 SPART Q8N0X7 Spartin chr13 Not Cancer Driver No 1 hippie 77 397 49 49 1
SPRED1-201 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 53 195 28 28 2
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 37 302 25 25 0
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 intact, hippie 36 202 12 12 21
TAX1BP1-202 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 43 429 29 29 0
TNFRSF10A-201 TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 39 175 14 14 0
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 38 111 14 14 9
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TRAF3-202 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 49 101 8 8 1
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TSC1-201 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 intact 94 735 53 53 11
TTR-201 TTR P02766 Transthyretin chr18 Not Cancer Driver No 1 hippie 18 25 5 5 50
UBB-201 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 2 intact, hippie 15 103 6 6 0
UBE2S-201 UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 Not Cancer Driver No 1 hippie 15 102 5 5 0
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 40 545 38 38 0
ULK1-201 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 1 hippie 125 591 66 66 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 2 hippie, biogrid 87 423 46 46 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 19 110 3 3 0
ZDHHC17-201 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 61 50 6 6 0