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PHGDH-208 ,PHGDH ,O43175
  • Number of Interaction partner in intact: 34
  • Number of Interaction partner in biogrid: 74
  • Number of Interaction partner in hippie: 253
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ABCC6-201 ABCC6 O95255 ATP-binding cassette sub-family C member 6 chr16 Not Cancer Driver No 1 hippie 149 133 17 17 78
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 96 43 5 5 4
ADH5-201 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 1 1 1
ADNP-205 ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 Not Cancer Driver No 1 hippie, biogrid 96 615 52 52 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
ALDOA-206 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie 36 65 7 7 3
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 101 771 75 75 2
ANO7-201 ANO7 Q6IWH7 Anoctamin-7 chr2 Not Cancer Driver No 1 hippie 111 150 23 23 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 2 intact, hippie 94 419 52 52 12
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARAF-202 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 61 181 26 26 0
ARIH1-201 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 1 hippie, biogrid 27 119 1 1 2
ASNS-202 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie, biogrid 58 11 0 0 3
ASS1-201 ASS1 P00966 Argininosuccinate synthase chr9 Not Cancer Driver No 1 hippie, biogrid 50 63 8 8 66
ASXL1-202 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 145 1307 125 125 0
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 25 183 12 12 0
BAG1-210 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 19 197 5 5 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 22 55 2 2 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 34 150 23 23 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 20 192 18 18 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 31 213 13 13 0
CAND1-208 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 118 88 6 6 0
CCDC25-201 CCDC25 Q86WR0 Coiled-coil domain-containing protein 25 chr8 Not Cancer Driver No 1 hippie, biogrid 12 75 3 3 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CCND1-201 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 hippie 47 32 25 25 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDC73-201 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 78 210 32 32 2
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 40 34 2 2 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 216 145 9 9 130
CHCHD3-201 CHCHD3 Q9NX63 MICOS complex subunit MIC19 chr7 Not Cancer Driver No 1 hippie 21 143 14 14 0
CHMP2B-201 CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 Not Cancer Driver No 1 hippie 22 186 20 20 4
CHMP4B-201 CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 21 201 20 20 2
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CLN3-243 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 hippie 42 69 5 5 8
CLN5-201 CLN5 O75503 Ceroid-lipofuscinosis neuronal protein 5 chr13 Not Cancer Driver No 1 hippie 25 16 1 1 11
CRY2-211 CRY2 Q49AN0 Cryptochrome-2 chr11 Not Cancer Driver No 1 hippie 54 100 8 8 0
CSNK1A1-202 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 34 46 2 2 0
CTBP2-205 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 36 94 4 4 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
CUL2-203 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 64 66 2 2 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CUL5-201 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 69 5 1 1 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
DCPS-201 DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 32 55 5 5 1
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX39B-202 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 36 34 6 6 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie, biogrid 98 100 10 10 0
EEF2K-201 EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 Not Cancer Driver No 1 hippie 80 311 30 30 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000636766 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 hippie 0 0 0 0 0
ENST00000647960 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 26 15 1 1 8
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPN1-202 EPN1 Q9Y6I3 Epsin-1 chr19 Not Cancer Driver No 2 hippie, biogrid 62 494 52 52 0
EPN3-201 EPN3 Q9H201 Epsin-3 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 59 525 54 54 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 3 intact, hippie 92 198 19 19 2
EZH2-203 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 74 284 32 32 11
FAF1-201 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 54 241 23 23 0
FBXO25-204 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 23 21 0 0 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FBXO7-201 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 49 243 24 24 1
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 289 232 15 15 17
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 92 231 26 26 69
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 289 1249 137 137 8
FUS-201 FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 27 525 27 27 16
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GABARAPL2-201 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 4 2 1 1 0
GAK-201 GAK O14976 Cyclin-G-associated kinase chr4 Not Cancer Driver No 1 intact, hippie 110 592 57 57 0
GALNT11-205 GALNT11 Q8NCW6 Polypeptide N-acetylgalactosaminyltransferase 11 chr7 Not Cancer Driver No 1 hippie, biogrid 49 91 14 14 0
GDPGP1-201 GDPGP1 Q6ZNW5 GDP-D-glucose phosphorylase 1 chr15 Not Cancer Driver No 1 hippie, biogrid 32 85 8 8 0
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
GPD1L-201 GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 Not Cancer Driver No 1 hippie, biogrid 28 13 1 1 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 21 10 0 0 0
GRWD1-201 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 32 188 9 9 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 34 148 6 6 0
GTF3C1-201 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 Not Cancer Driver No 1 hippie, biogrid 258 736 94 94 0
GTSE1-201 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 Not Cancer Driver No 1 intact, hippie 65 695 62 62 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HDAC5-213 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 93 720 61 61 0
HDAC6-201 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 122 409 35 35 0
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 290 22 22 4
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 82 252 28 28 0
HSPE1-201 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 6 3 0 0 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IK-201 IK Q13123 Protein Red chr5 Not Cancer Driver No 1 hippie, biogrid 39 482 33 33 0
ILF3-218 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie 57 676 39 39 0
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 30 72 7 7 0
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITSN1-206 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie 109 798 50 50 0
JOSD2-204 JOSD2 Q8TAC2 Josephin-2 chr19 Not Cancer Driver No 1 hippie 15 21 4 4 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
JUP-203 JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 81 242 24 24 0
KCTD15-213 KCTD15 Q96SI1 BTB/POZ domain-containing protein KCTD15 chr19 Not Cancer Driver No 1 hippie 32 89 13 13 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 771 7 2 2 22
L1TD1-201 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 91 543 72 72 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LDHB-201 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 32 15 1 1 10
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 46 65 13 13 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAD2L2-207 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 16 0 0 0 1
MAP1LC3A-201 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 19 24 1 1 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 4 17 0 0 0
MAP3K3-202 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 48 356 27 27 0
MAPK13-201 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 34 50 11 11 0
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MCU-202 MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 13 0 0 0
MDC1-201 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 175 1829 156 156 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MECOM-217 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 225 751 120 120 3
MEPCE-201 MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 46 449 29 29 0
METTL3-201 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 60 274 24 24 0
MORF4L1-201 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 32 163 11 11 0
MS4A4A-201 MS4A4A Q96JQ5 Membrane-spanning 4-domains subfamily A member 4A chr11 Not Cancer Driver No 1 intact, hippie 43 38 4 4 0
MTHFD1-220 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 hippie, biogrid 78 129 11 11 6
MYADM-204 MYADM Q96S97 Myeloid-associated differentiation marker chr19 Not Cancer Driver No 1 hippie, biogrid 50 0 0 0 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYL6-218 MYL6 P60660 Myosin light polypeptide 6 chr12 Not Cancer Driver No 1 hippie, biogrid 10 17 1 1 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NBR1-206 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie 88 562 41 41 0
NCSTN-201 NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 69 72 10 10 1
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NECAP1-201 NECAP1 Q8NC96 Adaptin ear-binding coat-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 31 140 19 19 0
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NFATC1-205 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 hippie, biogrid 127 727 99 99 0
NFX1-203 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 89 492 28 28 0
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NR4A1-204 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 Not Cancer Driver No 1 hippie 52 252 24 24 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDT9-201 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 25 177 14 14 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OCRL-202 OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 105 126 18 18 36
OGT-202 OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 111 90 9 9 2
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
PABPC1-201 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie, biogrid 53 317 32 32 0
PABPC4-202 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 68 255 40 40 0
PAGE4-201 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 13 102 13 13 0
PFKM-203 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 Not Cancer Driver No 1 hippie 56 70 5 5 8
PGAM1-201 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 12 70 4 4 0
PIAS4-201 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 40 143 18 18 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PJA1-203 PJA1 Q8NG27 E3 ubiquitin-protein ligase Praja-1 chrX Not Cancer Driver No 1 hippie 89 527 73 73 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 129 925 106 106 0
PLIN3-201 PLIN3 O60664 Perilipin-3 chr19 Not Cancer Driver No 1 hippie, biogrid 35 258 27 27 0
PLPBP-201 PLPBP O94903 Pyridoxal phosphate homeostasis protein chr8 Not Cancer Driver No 1 hippie 25 96 10 10 3
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 31 27 6 6 0
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie, biogrid 385 421 43 43 2
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PSAT1-202 PSAT1 Q9Y617 Phosphoserine aminotransferase chr9 Not Cancer Driver No 1 hippie, biogrid 39 3 0 0 3
PSPH-201 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 1 hippie, biogrid 31 21 2 2 3
RAD18-201 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 42 330 31 31 0
RAD23A-203 RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie, biogrid 41 284 34 34 0
RAD23B-201 RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 Not Cancer Driver No 1 hippie, biogrid 29 326 24 24 0
RBM39-201 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 53 228 16 16 0
RBX1-201 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 9 18 1 1 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 50 20 1 1 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 64 420 31 31 0
RIOK1-202 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 52 303 30 30 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
RNF5-203 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 Not Cancer Driver No 1 hippie 12 69 1 1 0
ROM1-201 ROM1 Q03395 Rod outer segment membrane protein 1 chr11 Not Cancer Driver No 1 intact, hippie 29 26 4 4 0
RPAP3-201 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 intact, hippie 34 334 20 20 0
RPS27A-201 RPS27A P62979 Ubiquitin-ribosomal protein eS31 fusion protein chr2 Not Cancer Driver No 1 hippie, biogrid 13 47 2 2 0
RPS6KB2-201 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 34 195 8 8 0
RPTOR-201 RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 149 242 18 18 0
S100A6-201 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie, biogrid 5 4 0 0 0
SAP18-207 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie, biogrid 14 100 9 9 0
SIRT2-201 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 Not Cancer Driver No 1 hippie 40 85 13 13 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC31A1-201 SLC31A1 O15431 High affinity copper uptake protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 12 28 3 3 0
SLC33A1-207 SLC33A1 O00400 Acetyl-coenzyme A transporter 1 chr3 Not Cancer Driver No 1 intact, hippie 43 54 5 5 2
SMARCA5-201 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 1 hippie, biogrid 73 364 26 26 0
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SMU1-201 SMU1 Q2TAY7 WD40 repeat-containing protein SMU1 chr9 Not Cancer Driver No 1 hippie, biogrid 35 15 0 0 0
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 41 98 8 8 0
SNW1-201 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 59 487 53 53 0
SON-202 SON P18583 Protein SON chr21 Not Cancer Driver No 1 hippie, biogrid 123 2114 111 111 0
SPDL1-201 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie 59 343 34 34 0
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
SRSF1-201 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 27 199 23 23 0
SRSF10-214 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie, biogrid 0 192 0 0 0
SRSF11-201 SRSF11 Q05519 Serine/arginine-rich splicing factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 25 362 19 19 0
SRSF5-217 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 23 189 15 15 0
SSRP1-201 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 hippie, biogrid 66 308 22 22 0
STAT1-201 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie, biogrid 100 144 16 16 23
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
STIP1-201 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 270 28 28 0
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 2 intact, hippie 49 233 20 20 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO4-201 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 6 69 4 4 0
SURF4-202 SURF4 O15260 Surfeit locus protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
SUZ12-201 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 55 483 32 32 3
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 36 202 12 12 21
TCERG1-201 TCERG1 O14776 Transcription elongation regulator 1 chr5 Not Cancer Driver No 1 hippie, biogrid 68 811 47 47 0
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 40 169 12 12 0
THRAP3-201 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie, biogrid 78 957 81 81 0
TMEM41B-204 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 16 48 2 2 0
TMPO-202 TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 50 414 32 32 0
TNFRSF1B-201 TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 40 231 21 21 0
TOP3B-201 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 76 151 11 11 0
TRA2A-201 TRA2A Q13595 Transformer-2 protein homolog alpha chr7 Not Cancer Driver No 1 hippie, biogrid 10 253 8 8 0
TRAF3IP1-201 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 46 512 33 33 3
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM55-202 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 100 278 59 59 0
TTN-215 TTN Q8WZ42 Titin chr2 Not Cancer Driver No 1 intact, hippie 3472 12945 1338 1338 10
TUBA1C-201 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 intact, hippie 26 50 2 2 0
TYMS-203 TYMS P04818 Thymidylate synthase chr18 Not Cancer Driver No 1 hippie, biogrid 18 41 0 0 0
U2AF1-201 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie, biogrid 0 73 0 0 2
U2AF2-201 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie, biogrid 61 191 24 24 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBE2L6-201 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 Not Cancer Driver No 1 hippie 13 7 1 1 0
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 25 32 4 4 0
UBE2N-201 UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie, biogrid 19 24 1 1 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 64 581 61 61 8
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UQCC3-201 UQCC3 Q6UW78 Ubiquinol-cytochrome-c reductase complex assembly factor 3 chr11 Not Cancer Driver No 1 hippie, biogrid 6 54 5 5 1
UQCRFS1-201 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 27 47 1 1 1
USP7-201 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie, biogrid 135 215 34 34 7
UTP14A-201 UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 63 629 56 56 0
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie, biogrid 20 184 11 11 0
VASN-201 VASN Q6EMK4 Vasorin chr16 Not Cancer Driver No 1 hippie, biogrid 29 234 7 7 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VTN-201 VTN P04004 Vitronectin chr17 Not Cancer Driver No 1 hippie, biogrid 52 168 20 20 0
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WDTC1-201 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 66 154 19 19 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 36 929 33 33 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZNF598-202 ZNF598 Q86UK7 E3 ubiquitin-protein ligase ZNF598 chr16 Not Cancer Driver No 1 hippie 68 567 47 47 0