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PIP5K1A-202 ,PIP5K1A ,Q99755
  • Number of Interaction partner in intact: 26
  • Number of Interaction partner in biogrid: 79
  • Number of Interaction partner in hippie: 131
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABT1-201 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 Not Cancer Driver No 1 hippie, biogrid 40 157 17 17 0
AGRN-201 AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie 145 467 32 32 6
AHCYL2-201 AHCYL2 Q96HN2 Adenosylhomocysteinase 3 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 57 209 12 12 0
APBA1-201 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 117 558 78 78 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie 22 4 2 2 2
ARF5-201 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 1 hippie 15 11 1 1 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 2 hippie, biogrid 16 5 0 0 0
ARHGAP22-201 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 107 449 65 65 0
ARIH1-201 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 3 hippie, biogrid 27 119 1 1 2
ARL14-201 ARL14 Q8N4G2 ADP-ribosylation factor-like protein 14 chr3 Not Cancer Driver No 1 intact, hippie 16 15 2 2 0
BRAF-220 BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 hippie 755 311 30 30 35
BTK-201 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 109 114 21 21 83
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
CADPS-203 CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 Not Cancer Driver No 1 hippie 201 336 41 41 0
CAMK2A-201 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 hippie, biogrid 62 62 10 10 7
CAMK2D-215 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 Not Cancer Driver No 2 intact, hippie, biogrid 0 0 0 0 0
CAPN2-201 CAPN2 P17655 Calpain-2 catalytic subunit chr1 Not Cancer Driver No 1 hippie, biogrid 52 46 6 6 0
CASP3-201 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 19 64 1 1 0
CASP8-218 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 intact 116 106 11 11 1
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
CCDC85A-201 CCDC85A Q96PX6 Coiled-coil domain-containing protein 85A chr2 Not Cancer Driver No 1 hippie, biogrid 114 403 92 92 0
CCDC97-201 CCDC97 Q96F63 Coiled-coil domain-containing protein 97 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 42 251 26 26 0
CD6-201 CD6 P30203 T-cell differentiation antigen CD6 chr11 Not Cancer Driver No 1 hippie, biogrid 70 270 36 36 0
CENPB-201 CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 2 hippie, biogrid 33 374 16 16 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CLEC4G-201 CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 intact 32 35 3 3 0
CSNK1A1-202 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie, biogrid 34 46 2 2 0
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
DCAF5-201 DCAF5 Q96JK2 DDB1- and CUL4-associated factor 5 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 93 522 63 63 0
DGKZ-205 DGKZ Q13574 Diacylglycerol kinase zeta chr11 Not Cancer Driver No 1 hippie, biogrid 65 411 30 30 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 34 174 18 18 0
DNAJC5-201 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 19 46 5 5 1
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
FLNC-201 FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie, biogrid 436 1451 234 234 7
FRYL-202 FRYL O94915 Protein furry homolog-like chr4 Not Cancer Driver No 1 hippie, biogrid 237 666 47 47 0
FTL-201 FTL P02792 Ferritin light chain chr19 Not Cancer Driver No 1 hippie, biogrid 15 36 6 6 2
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GCH1-204 GCH1 P30793 GTP cyclohydrolase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 14 102 3 3 35
GFOD1-203 GFOD1 Q9NXC2 Glucose-fructose oxidoreductase domain-containing protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 53 35 3 3 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GPC3-201 GPC3 P51654 Glypican-3 chrX Census Yes 2 hippie, biogrid 55 87 7 7 1
GPR156-202 GPR156 Q8NFN8 Probable G-protein coupled receptor 156 chr3 Not Cancer Driver No 2 hippie, biogrid 91 419 55 55 0
HEATR3-201 HEATR3 Q7Z4Q2 HEAT repeat-containing protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 56 134 7 7 2
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie, biogrid 129 16 2 2 10
HTATSF1-201 HTATSF1 O43719 HIV Tat-specific factor 1 chrX Not Cancer Driver No 1 hippie, biogrid 78 575 57 57 0
IMPDH1-208 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 Not Cancer Driver No 2 hippie, biogrid 60 12 1 1 7
IMPDH2-201 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 52 6 1 1 0
ITGB1BP2-201 ITGB1BP2 Q9UKP3 Integrin beta-1-binding protein 2 chrX Not Cancer Driver No 1 hippie 40 137 14 14 0
KBTBD7-201 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 63 107 6 6 0
KCNJ2-201 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 85 49 7 7 12
KCTD17-202 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 18 176 10 10 1
KLHDC3-202 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 Not Cancer Driver No 2 hippie, biogrid 34 12 0 0 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 771 7 2 2 22
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 88 408 46 46 0
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 36 94 8 8 0
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 29 55 4 4 1
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LIN28A-202 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 Not Cancer Driver No 1 intact 30 86 11 11 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
MAGEB2-201 MAGEB2 O15479 Melanoma-associated antigen B2 chrX Not Cancer Driver No 1 hippie, biogrid 87 128 32 32 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 4 17 0 0 0
MAP4K2-201 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 Not Cancer Driver No 1 hippie 59 243 16 16 0
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MED4-201 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 23 161 13 13 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MTMR4-201 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 Not Cancer Driver No 1 hippie 104 476 43 43 0
MYH9-201 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 247 1124 126 126 13
NEDD4-208 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 99 717 55 55 0
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 272 10 0 0 12
NRP1-206 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 2 hippie, biogrid 112 212 25 25 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
PELP1-208 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 75 605 35 35 0
PER2-201 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie, biogrid 118 783 72 72 1
PFDN2-201 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 2 hippie, biogrid 16 111 10 10 0
PGBD5-201 PGBD5 Q8N414 PiggyBac transposable element-derived protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 60 127 1 1 0
PIP4K2A-202 PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 Not Cancer Driver No 2 intact, hippie, biogrid 41 123 12 12 0
PIP5K1C-201 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 Not Cancer Driver No 3 intact, hippie, biogrid 82 359 51 51 1
PIP5KL1-202 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 Not Cancer Driver No 1 hippie 20 74 4 4 0
PLD1-201 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 hippie 126 133 21 21 1
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 71 98 5 5 0
PLXDC2-203 PLXDC2 Q6UX71 Plexin domain-containing protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 122 150 42 42 0
PREX1-201 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 Not Cancer Driver No 1 hippie, biogrid 232 310 48 48 0
PRKCA-202 PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 2 intact, hippie, biogrid 70 155 17 17 0
PRPS2-202 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 42 4 1 1 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 52 2 2 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RABGGTB-201 RABGGTB P53611 Geranylgeranyl transferase type-2 subunit beta chr1 Not Cancer Driver No 3 hippie, biogrid 40 4 1 1 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RAD21-201 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 2 intact, hippie, biogrid 84 421 56 56 3
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 50 20 1 1 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RHOQ-201 RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 19 0 0 0 0
RHOU-201 RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 28 63 6 6 0
RPL10-202 RPL10 P27635 Large ribosomal subunit protein uL16 chrX Census, Compendium Yes 1 intact, hippie 41 9 2 2 4
RPS16-201 RPS16 P62249 Small ribosomal subunit protein uS9 chr19 Not Cancer Driver No 1 hippie, biogrid 13 14 1 1 0
RUNDC3A-202 RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 Not Cancer Driver No 1 hippie, biogrid 33 176 8 8 0
SERBP1-204 SERBP1 Q8NC51 SERPINE1 mRNA-binding protein 1 chr1 Not Cancer Driver No 1 hippie 40 408 40 40 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 43 435 19 19 0
SKAP1-201 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 58 132 24 24 0
SMURF1-201 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 60 257 19 19 0
SNAPC1-201 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 Not Cancer Driver No 1 hippie, biogrid 24 159 11 11 0
SNAPC3-202 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 Not Cancer Driver No 1 hippie, biogrid 23 99 2 2 0
SNAPC4-206 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 Not Cancer Driver No 1 hippie, biogrid 118 1103 79 79 0
SNRNP70-206 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 28 417 27 27 0
SRSF6-201 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 29 259 12 12 0
STAG2-211 STAG2 Q8N3U4 Cohesin subunit SA-2 chrX Census, Compendium Yes 2 intact, hippie, biogrid 123 331 31 31 3
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 21 165 9 9 0
TEC-201 TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 66 57 11 11 0
TGFBR3-201 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 104 268 36 36 0
TMED9-201 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 12 22 2 2 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM41-201 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 44 388 19 19 0
TUT1-205 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 Not Cancer Driver No 1 intact, hippie 78 411 44 44 0
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
ZBTB7C-221 ZBTB7C A1YPR0 Zinc finger and BTB domain-containing protein 7C chr18 Not Cancer Driver No 1 hippie, biogrid 58 251 32 32 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 2 hippie, biogrid 36 929 33 33 0
ZKSCAN8-201 ZKSCAN8 Q15776 Zinc finger protein with KRAB and SCAN domains 8 chr6 Not Cancer Driver No 1 hippie, biogrid 55 280 29 29 0
ZNF467-201 ZNF467 Q7Z7K2 Zinc finger protein 467 chr7 Not Cancer Driver No 1 hippie, biogrid 55 347 27 27 0
ZNF653-201 ZNF653 Q96CK0 Zinc finger protein 653 chr19 Not Cancer Driver No 1 hippie, biogrid 62 375 41 41 0
ZSCAN31-201 ZSCAN31 Q96LW9 Zinc finger and SCAN domain-containing protein 31 chr6 Not Cancer Driver No 2 hippie, biogrid 51 195 23 23 0