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PKLR-201 ,PKLR ,P30613
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 30
  • Number of Interaction partner in hippie: 46
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ANXA1-201 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 36 61 7 7 0
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 hippie 106 224 28 28 0
BRCA2-201 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 biogrid 310 1545 152 152 46
BUB1B-201 BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie, biogrid 69 484 26 26 7
CLEC4G-201 CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 hippie 32 35 3 3 0
CPNE7-201 CPNE7 Q9UBL6 Copine-7 chr16 Not Cancer Driver No 1 hippie 53 51 5 5 0
CSK-201 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 biogrid 37 18 1 1 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 54 102 2 2 0
CYP4B1-201 CYP4B1 P13584 Cytochrome P450 4B1 chr1 Not Cancer Driver No 1 hippie, biogrid 96 8 2 2 0
DKK2-201 DKK2 Q9UBU2 Dickkopf-related protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 84 71 17 17 0
DVL2-201 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 72 515 52 52 0
EEF1A2-201 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie, biogrid 58 121 17 17 3
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 biogrid 147 188 33 33 3
EPHB2-204 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 biogrid 149 120 11 11 7
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
FCER1A-203 FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 64 13 0 0 0
ISX-202 ISX Q2M1V0 Intestine-specific homeobox chr22 Census Yes 1 hippie, biogrid 50 103 27 27 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
LRRC3B-201 LRRC3B Q96PB8 Leucine-rich repeat-containing protein 3B chr3 Not Cancer Driver No 1 hippie, biogrid 62 25 4 4 0
MAPK12-201 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 Not Cancer Driver No 1 biogrid 27 63 5 5 0
MRAS-202 MRAS O14807 Ras-related protein M-Ras chr3 Not Cancer Driver No 1 hippie, biogrid 17 50 10 10 3
MYOC-201 MYOC Q99972 Myocilin chr1 Not Cancer Driver No 1 hippie 76 197 36 36 49
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NT5DC1-201 NT5DC1 Q5TFE4 5'-nucleotidase domain-containing protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 33 58 2 2 0
ODF3-201 ODF3 Q96PU9 Outer dense fiber protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 16 176 11 11 0
OTUD5-201 OTUD5 Q96G74 OTU domain-containing protein 5 chrX Not Cancer Driver No 1 hippie, biogrid 32 430 24 24 4
PAICS-207 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 16 35 1 1 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 36 300 19 19 2
PCGF3-201 PCGF3 Q3KNV8 Polycomb group RING finger protein 3 chr4 Not Cancer Driver No 1 hippie, biogrid 26 47 6 6 0
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 19 22 2 2 1
PI15-201 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 66 4 1 1 0
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 53 58 11 11 0
PXN-201 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 41 342 14 14 0
RASL11A-201 RASL11A Q6T310 Ras-like protein family member 11A chr13 Not Cancer Driver No 1 hippie, biogrid 22 40 2 2 0
RFXANK-201 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 hippie, biogrid 13 122 4 4 1
SAV1-201 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 24 245 13 13 0
SBDS-201 SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 Census Yes 1 hippie, biogrid 26 12 1 1 2
SPIN4-201 SPIN4 Q56A73 Spindlin-4 chrX Not Cancer Driver No 1 hippie, biogrid 28 63 9 9 0
SRD5A2-201 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 20
SRPK3-202 SRPK3 Q9UPE1 SRSF protein kinase 3 chrX Not Cancer Driver No 1 hippie, biogrid 42 218 20 20 0
SUMO4-201 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 6 69 4 4 0
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 40 169 12 12 0
TMEM69-201 TMEM69 Q5SWH9 Transmembrane protein 69 chr1 Not Cancer Driver No 1 hippie, biogrid 12 4 0 0 0
UBE2J2-202 UBE2J2 Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 chr1 Not Cancer Driver No 1 hippie, biogrid 32 51 5 5 0
USP3-202 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 Not Cancer Driver No 1 hippie, biogrid 48 45 3 3 0
USPL1-201 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 Not Cancer Driver No 1 hippie, biogrid 65 579 33 33 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0