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PKP1-202 ,PKP1 ,Q13835
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 122
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACO2-201 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 intact 77 172 16 16 5
ALDH2-201 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 Census Yes 1 hippie, biogrid 43 44 1 1 1
ANXA2-204 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie, biogrid 38 21 2 2 0
ANXA9-201 ANXA9 O76027 Annexin A9 chr1 Not Cancer Driver No 1 hippie, biogrid 35 42 5 5 0
ARAF-202 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 intact, hippie 61 181 26 26 0
ARMC8-210 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 intact, hippie 42 7 0 0 0
ATP6V0A1-202 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 1 hippie 73 86 12 12 3
BICDL2-203 BICDL2 A1A5D9 BICD family-like cargo adapter 2 chr16 Not Cancer Driver No 1 hippie 34 446 33 33 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BLMH-201 BLMH Q13867 Bleomycin hydrolase chr17 Not Cancer Driver No 1 hippie, biogrid 38 15 1 1 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 34 150 23 23 0
C18orf21-205 C18orf21 Q32NC0 UPF0711 protein C18orf21 chr18 Not Cancer Driver No 1 hippie, biogrid 12 113 4 4 0
CA8-201 CA8 P35219 Carbonic anhydrase-related protein chr8 Not Cancer Driver No 2 hippie, biogrid 44 35 2 2 1
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie, biogrid 21 19 0 0 0
CARD10-201 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 Not Cancer Driver No 1 hippie 78 478 35 35 0
CASP14-201 CASP14 P31944 Caspase-14 chr19 Not Cancer Driver No 1 hippie, biogrid 42 84 10 10 0
CCDC51-201 CCDC51 Q96ER9 Mitochondrial potassium channel chr3 Not Cancer Driver No 3 hippie, biogrid 37 138 15 15 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CCDC82-218 CCDC82 Q8N4S0 Coiled-coil domain-containing protein 82 chr11 Not Cancer Driver No 2 hippie, biogrid 44 327 23 23 0
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
CD109-201 CD109 Q6YHK3 CD109 antigen chr6 Not Cancer Driver No 1 hippie, biogrid 151 54 9 9 0
CEP76-201 CEP76 Q8TAP6 Centrosomal protein of 76 kDa chr18 Not Cancer Driver No 1 hippie 41 97 4 4 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHD4-206 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 312 978 118 118 6
CIDEA-201 CIDEA O60543 Lipid transferase CIDEA chr18 Not Cancer Driver No 3 hippie, biogrid 35 32 1 1 0
COASY-201 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie, biogrid 43 50 4 4 1
CPLANE2-201 CPLANE2 Q9BU20 Ciliogenesis and planar polarity effector 2 chr1 Not Cancer Driver No 1 hippie 28 21 3 3 0
CPLX3-201 CPLX3 Q8WVH0 Complexin-3 chr15 Not Cancer Driver No 1 hippie, biogrid 19 150 18 18 0
CSGALNACT1-217 CSGALNACT1 Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 64 132 22 22 3
CTSD-201 CTSD P07339 Cathepsin D chr11 Not Cancer Driver No 1 hippie, biogrid 49 6 2 2 2
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
DDX39B-202 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 36 34 6 6 0
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 91 302 32 32 18
DSC1-202 DSC1 Q08554 Desmocollin-1 chr18 Not Cancer Driver No 2 hippie, biogrid 161 268 53 53 0
DSG1-201 DSG1 Q02413 Desmoglein-1 chr18 Not Cancer Driver No 2 hippie, biogrid 197 504 106 106 0
DSP-201 DSP P15924 Desmoplakin chr6 Not Cancer Driver No 2 hippie, biogrid 354 1127 146 146 6
ENST00000649772 SPICE1 Q8N0Z3 Spindle and centriole-associated protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 88 733 76 76 0
ENST00000651531 TGM3 Q08188 Protein-glutamine gamma-glutamyltransferase E chr20 Not Cancer Driver No 1 hippie, biogrid 111 77 14 14 0
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FBXL4-202 FBXL4 Q9UKA2 F-box/LRR-repeat protein 4 chr6 Not Cancer Driver No 2 hippie, biogrid 60 25 1 1 7
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 289 232 15 15 17
FCF1-201 FCF1 Q9Y324 rRNA-processing protein FCF1 homolog chr14 Not Cancer Driver No 2 hippie, biogrid 19 46 3 3 0
FHIP1A-201 FHIP1A Q05DH4 FHF complex subunit HOOK-interacting protein 1A chr4 Not Cancer Driver No 1 intact 32 341 7 7 0
FLG-201 FLG P20930 Filaggrin chr1 Not Cancer Driver No 1 hippie, biogrid 1351 4059 1373 1373 0
FLG2-201 FLG2 Q5D862 Filaggrin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 89 2255 60 60 0
FNDC5-201 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 13 74 6 6 0
FOS-201 FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie, biogrid 37 247 28 28 0
FOXI2-201 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 intact, hippie 28 166 20 20 0
FSTL1-201 FSTL1 Q12841 Follistatin-related protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 36 51 5 5 0
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GABARAPL2-201 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 4 2 1 1 0
GABPA-202 GABPA Q06546 GA-binding protein alpha chain chr21 Not Cancer Driver No 1 hippie, biogrid 49 104 7 7 0
GDI2-203 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 intact 34 23 1 1 0
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 84 859 71 71 0
GOSR1-201 GOSR1 O95249 Golgi SNAP receptor complex member 1 chr17 Not Cancer Driver No 1 intact, hippie 14 108 8 8 0
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
GPATCH2L-201 GPATCH2L Q9NWQ4 G patch domain-containing protein 2-like chr14 Not Cancer Driver No 1 hippie, biogrid 39 380 31 31 0
GTF2IRD1-201 GTF2IRD1 Q9UHL9 General transcription factor II-I repeat domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 102 380 41 41 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 hippie, biogrid 378 366 163 163 15
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 33 290 22 22 4
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 hippie 70 489 49 49 0
HSF2BP-201 HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 hippie 27 23 0 0 1
IVL-201 IVL P07476 Involucrin chr1 Not Cancer Driver No 1 hippie, biogrid 28 589 28 28 0
JADE1-201 JADE1 Q6IE81 Protein Jade-1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 74 410 34 34 0
KDELR2-201 KDELR2 P33947 ER lumen protein-retaining receptor 2 chr7 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 1
KIF3A-202 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 Not Cancer Driver No 2 hippie, biogrid 49 409 35 35 0
KRT14-201 KRT14 P02533 Keratin, type I cytoskeletal 14 chr17 Not Cancer Driver No 1 hippie 40 185 22 22 39
KRT15-201 KRT15 P19012 Keratin, type I cytoskeletal 15 chr17 Not Cancer Driver No 1 hippie 66 193 17 17 0
KRT18-201 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie 46 179 17 17 4
KRT5-201 KRT5 P13647 Keratin, type II cytoskeletal 5 chr12 Not Cancer Driver No 1 hippie 75 195 36 36 46
KRT8-218 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie 49 225 23 23 3
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 90 261 33 33 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
LSM1-201 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 Not Cancer Driver No 1 intact 15 6 1 1 0
MBNL1-201 MBNL1 Q9NR56 Muscleblind-like protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 154 14 14 0
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MICU3-201 MICU3 Q86XE3 Calcium uptake protein 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 47 90 3 3 0
MOSPD2-201 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact, hippie 39 143 10 10 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NDUFS5-202 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 11 31 3 3 0
NEK2-202 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 Not Cancer Driver No 1 hippie 44 93 12 12 0
NFKBID-201 NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 hippie 41 125 16 16 0
NRSN1-204 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 41 18 6 6 0
OAZ3-202 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 Not Cancer Driver No 1 hippie, biogrid 22 33 1 1 0
ODF2-220 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 intact 99 609 72 72 0
OPN5-202 OPN5 Q6U736 Opsin-5 chr6 Not Cancer Driver No 1 hippie, biogrid 62 0 0 0 0
OR2A4-201 OR2A4 O95047 Olfactory receptor 2A4 chr6 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
P2RX6-202 P2RX6 O15547 P2X purinoceptor 6 chr22 Not Cancer Driver No 1 hippie, biogrid 22 43 1 1 0
PDE4DIP-205 PDE4DIP Q5VU43 Myomegalin chr1 Census, Compendium Yes 1 hippie, biogrid 380 1640 276 276 0
PEMT-204 PEMT Q9UBM1 Phosphatidylethanolamine N-methyltransferase chr17 Not Cancer Driver No 1 hippie, biogrid 14 1 0 0 0
PHF11-202 PHF11 Q9UIL8 PHD finger protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 22 82 9 9 0
PHF8-204 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 hippie, biogrid 104 603 58 58 1
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 46 99 8 8 24
PKP2-201 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 intact 139 435 77 77 8
PLD5-208 PLD5 Q8N7P1 Inactive phospholipase D5 chr1 Not Cancer Driver No 1 hippie, biogrid 124 62 14 14 0
POC5-202 POC5 Q8NA72 Centrosomal protein POC5 chr5 Not Cancer Driver No 1 hippie 35 356 26 26 0
POF1B-201 POF1B Q8WVV4 Protein POF1B chrX Not Cancer Driver No 1 hippie, biogrid 121 386 82 82 1
POLR2L-201 POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
PPP2R2B-203 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie, biogrid 66 76 11 11 1
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PTDSS1-202 PTDSS1 P48651 Phosphatidylserine synthase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 56 44 4 4 3
RANBP9-201 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 42 414 15 15 0
RBFOX1-211 RBFOX1 Q9NWB1 RNA binding protein fox-1 homolog 1 chr16 Compendium Yes 1 hippie, biogrid 139 182 72 72 0
RBM24-202 RBM24 Q9BX46 RNA-binding protein 24 chr6 Not Cancer Driver No 2 hippie, biogrid 24 20 3 3 0
SERPINB12-201 SERPINB12 Q96P63 Serpin B12 chr18 Not Cancer Driver No 1 hippie, biogrid 59 21 6 6 0
SERPINB3-201 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie, biogrid 116 47 23 23 0
SERPINB5-201 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie, biogrid 42 50 4 4 0
SGO2-201 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 hippie 111 1029 91 91 0
SLC37A4-201 SLC37A4 O43826 Glucose-6-phosphate exchanger SLC37A4 chr11 Not Cancer Driver No 1 hippie, biogrid 26 17 1 1 28
SMARCB1-213 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact 55 141 26 26 3
SPICE1-201 SPICE1 Q8N0Z3 Spindle and centriole-associated protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 88 734 78 78 0
SRRT-213 SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 Not Cancer Driver No 1 hippie, biogrid 96 596 68 68 0
SSUH2-216 SSUH2 Q9Y2M2 Protein SSUH2 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 46 77 6 6 1
ST6GALNAC6-205 ST6GALNAC6 Q969X2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 chr9 Not Cancer Driver No 1 hippie, biogrid 29 87 7 7 0
STX17-201 STX17 P56962 Syntaxin-17 chr9 Not Cancer Driver No 1 hippie, biogrid 24 81 6 6 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUZ12-201 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 55 483 32 32 3
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 36 202 12 12 21
TEX10-201 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 hippie, biogrid 74 103 10 10 0
TFG-201 TFG Q92734 Protein TFG chr3 Census, Compendium Yes 2 hippie, biogrid 25 292 19 19 2
TGM3-201 TGM3 Q08188 Protein-glutamine gamma-glutamyltransferase E chr20 Not Cancer Driver No 1 hippie, biogrid 111 86 15 15 0
TNS2-201 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 intact, hippie 97 800 47 47 0
TUBG1-201 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 42 44 9 9 3
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UCHL5-206 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 Not Cancer Driver No 1 hippie 23 41 2 2 0
USP1-201 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 45 405 20 20 0
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 67 316 45 45 1
WIPI1-201 WIPI1 Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 chr17 Not Cancer Driver No 1 hippie 33 113 9 9 0
ZC3HC1-202 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 44 252 19 19 0
ZDHHC19-201 ZDHHC19 Q8WVZ1 Palmitoyltransferase ZDHHC19 chr3 Not Cancer Driver No 1 hippie, biogrid 40 35 9 9 0