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PLEKHO1-201 ,PLEKHO1 ,Q53GL0
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 40
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADAM33-202 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 Not Cancer Driver No 1 hippie 81 169 23 23 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 99 158 19 19 4
AKT2-206 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 57 84 9 9 2
AKT3-217 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 hippie 71 131 19 19 3
AMY1A-201 AMY1C P0DTE8 Alpha-amylase 1C chr1 Not Cancer Driver No 1 biogrid 9 29 0 0 0
AMY1B-201 AMY1C P0DTE8 Alpha-amylase 1C chr1 Not Cancer Driver No 1 biogrid 9 29 0 0 0
AMY1C-202 AMY1C P0DTE8 Alpha-amylase 1C chr1 Not Cancer Driver No 1 biogrid 9 29 0 0 0
BNIP2-211 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 Not Cancer Driver No 1 hippie 22 146 12 12 0
BRICD5-202 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie 19 82 6 6 0
C4orf3-202 C4orf3 Q8WVX3 Uncharacterized protein C4orf3 chr4 Not Cancer Driver No 1 hippie 9 18 5 5 0
CAPZA1-201 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 31 42 3 3 0
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie, biogrid 21 19 0 0 0
CAPZB-201 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 2 hippie, biogrid 17 66 1 1 0
CENPV-201 CENPV Q7Z7K6 Centromere protein V chr17 Not Cancer Driver No 2 hippie, biogrid 9 151 2 2 0
CEP19-202 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 1 hippie 20 73 11 11 0
COL8A2-202 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 Not Cancer Driver No 1 hippie 12 561 4 4 4
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 47 75 6 6 4
CYP4F2-202 CYP4F2 P78329 Cytochrome P450 4F2 chr19 Not Cancer Driver No 1 hippie 110 17 2 2 0
DDX51-202 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 Not Cancer Driver No 2 hippie, biogrid 40 244 8 8 0
DNAJB1-201 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 26 196 20 20 0
DOK2-201 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 2 hippie, biogrid 40 255 21 21 0
FLNB-201 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 257 1187 123 123 19
FLNC-201 FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 2 hippie, biogrid 436 1451 234 234 7
FTSJ3-201 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 2 hippie, biogrid 75 535 48 48 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 2 hippie, biogrid 63 312 40 40 0
GLYR1-201 GLYR1 Q49A26 Cytokine-like nuclear factor N-PAC chr16 Not Cancer Driver No 1 hippie, biogrid 55 201 17 17 0
GNAO1-201 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 29 10 0 0 14
GTPBP10-201 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 Not Cancer Driver No 2 hippie, biogrid 31 52 1 1 0
GTPBP2-202 GTPBP2 Q9BX10 GTP-binding protein 2 chr6 Not Cancer Driver No 2 hippie, biogrid 45 91 5 5 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie, biogrid 129 16 2 2 10
IFI35-203 IFI35 P80217 Interferon-induced 35 kDa protein chr17 Not Cancer Driver No 1 hippie 24 63 10 10 0
KBTBD7-201 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 1 hippie, biogrid 63 107 6 6 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 771 7 2 2 22
LRP10-201 LRP10 Q7Z4F1 Low-density lipoprotein receptor-related protein 10 chr14 Not Cancer Driver No 1 hippie 75 237 26 26 0
MMD-201 MMD Q15546 Monocyte to macrophage differentiation factor chr17 Not Cancer Driver No 1 hippie 16 0 0 0 0
MYBBP1A-201 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 hippie, biogrid 100 468 37 37 0
NAPB-201 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 1 hippie 20 29 2 2 0
NLE1-202 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 Not Cancer Driver No 2 hippie, biogrid 43 21 2 2 0
NMNAT1-201 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 31 49 5 5 26
NOC2L-201 NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 2 hippie, biogrid 54 281 22 22 0
NOC3L-201 NOC3L Q8WTT2 Nucleolar complex protein 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 49 284 21 21 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NVL-201 NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 2 hippie, biogrid 78 270 26 26 0
OGT-202 OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 111 90 9 9 2
PDCD11-201 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 2 hippie, biogrid 167 487 49 49 0
PDIA6-201 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 hippie 41 82 8 8 0
PLEKHO1-201 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 1 hippie 44 343 36 36 0
PPAN-201 PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie 42 258 23 23 0
PPAN-P2RY11-202 PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie 43 276 25 25 0
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 35 64 5 5 0
RBM28-201 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie, biogrid 71 513 51 51 1
RPL26L1-201 RPL26L1 Q9UNX3 Ribosomal protein uL24-like chr5 Not Cancer Driver No 2 hippie, biogrid 15 107 9 9 0
RPL3-201 RPL3 P39023 Large ribosomal subunit protein uL3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 80 4 4 0
RPL5-202 RPL5 P46777 Large ribosomal subunit protein uL18 chr1 Census Yes 1 hippie, biogrid 39 96 10 10 2
RPS20-201 RPS20 P60866 Small ribosomal subunit protein uS10 chr8 Not Cancer Driver No 1 hippie 12 54 5 5 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SDAD1-201 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 44 291 15 15 0
SEC24D-201 SEC24D O94855 Protein transport protein Sec24D chr4 Not Cancer Driver No 2 hippie, biogrid 91 322 36 36 2
SMAD5-211 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 25 172 6 6 0
SMURF1-201 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 60 257 19 19 0
SPTY2D1-201 SPTY2D1 Q68D10 Protein SPT2 homolog chr11 Not Cancer Driver No 2 hippie, biogrid 69 674 68 68 0
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie, biogrid 54 458 45 45 0
SUPT5H-204 SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 115 574 58 58 0
THSD7B-201 THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 hippie 562 95 20 20 0
TMEM218-218 TMEM218 A2RU14 Transmembrane protein 218 chr11 Not Cancer Driver No 1 hippie 13 0 0 0 2
TNF-208 TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 22 45 2 2 0
TRAF3IP3-203 TRAF3IP3 Q9Y228 TRAF3-interacting JNK-activating modulator chr1 Not Cancer Driver No 1 hippie 75 353 54 54 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TRAM1L1-201 TRAM1L1 Q8N609 Translocating chain-associated membrane protein 1-like 1 chr4 Not Cancer Driver No 1 hippie 54 40 11 11 0
TRMT1L-201 TRMT1L Q7Z2T5 TRMT1-like protein chr1 Not Cancer Driver No 2 hippie, biogrid 51 242 12 12 0
TSPAN33-201 TSPAN33 Q86UF1 Tetraspanin-33 chr7 Not Cancer Driver No 1 hippie 19 0 0 0 0
TSPO2-202 TSPO2 Q5TGU0 Translocator protein 2 chr6 Not Cancer Driver No 1 hippie 17 7 3 3 0
UBA6-201 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 Not Cancer Driver No 2 hippie, biogrid 106 90 7 7 0
URB1-201 URB1 O60287 Nucleolar pre-ribosomal-associated protein 1 chr21 Not Cancer Driver No 2 hippie, biogrid 49 180 2 2 0
USP7-201 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 2 hippie, biogrid 135 215 34 34 7
VAMP3-201 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie 8 17 1 1 0
WDR45B-201 WDR45B Q5MNZ6 WD repeat domain phosphoinositide-interacting protein 3 chr17 Not Cancer Driver No 2 hippie, biogrid 38 8 0 0 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie 32 127 16 16 0