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PRKCZ-201 ,PRKCZ ,Q05513
  • Number of Interaction partner in intact: 142
  • Number of Interaction partner in biogrid: 141
  • Number of Interaction partner in hippie: 388
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 106 609 53 53 2
ACAT1-201 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 29 32 1 1 10
ACLY-201 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 88 114 9 9 0
ACTN4-201 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 110 244 36 36 7
ACTR3-201 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 24 16 2 2 0
ADAP1-201 ADAP1 O75689 Arf-GAP with dual PH domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 24 31 3 3 0
ADCY5-202 ADCY5 O95622 Adenylate cyclase type 5 chr3 Not Cancer Driver No 1 hippie 181 271 17 17 3
ADH1C-204 ADH1C P00326 Alcohol dehydrogenase 1C chr4 Not Cancer Driver No 1 hippie 90 7 5 5 0
AFAP1-201 AFAP1 Q8N556 Actin filament-associated protein 1 chr4 Not Cancer Driver No 1 hippie 64 489 37 37 0
AGER-206 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 Not Cancer Driver No 1 intact, hippie 17 297 12 12 0
AHCY-201 AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 6
AHSA1-201 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 33 147 14 14 0
AHSG-202 AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 1 intact, hippie, biogrid 61 132 33 33 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 61 166 20 20 10
AJUBA-201 AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 Compendium Yes 1 hippie 42 308 14 14 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 2 intact, hippie 99 158 19 19 4
AKT2-206 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 57 84 9 9 2
AKT3-217 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 2 intact, hippie 71 131 19 19 3
ALDH18A1-202 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 Not Cancer Driver No 1 intact, hippie, biogrid 68 86 8 8 13
AMHR2-201 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 Not Cancer Driver No 1 biogrid 67 118 9 9 8
ANXA2-204 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 38 21 2 2 0
AP2A2-202 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 1 intact, hippie 77 145 10 10 0
AP2M1-201 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 40 41 7 7 1
AP3S1-201 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
API5-208 API5 Q9BZZ5 Apoptosis inhibitor 5 chr11 Not Cancer Driver No 1 hippie 38 92 4 4 0
APPL1-201 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 35 293 18 18 1
ARHGDIA-201 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 18 50 4 4 0
ARMC8-210 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie, biogrid 42 7 0 0 0
ASPH-203 ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 intact, hippie 80 374 33 33 1
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 intact, hippie, biogrid 76 115 14 14 6
ATP1B3-201 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 Not Cancer Driver No 1 hippie, biogrid 19 6 0 0 0
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 2 intact, hippie 13 112 7 7 0
BASP1-201 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 12 227 12 12 0
BCL10-202 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 1 intact, hippie 20 153 14 14 0
BEGAIN-202 BEGAIN Q9BUH8 Brain-enriched guanylate kinase-associated protein chr14 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 0
BLVRA-201 BLVRA P53004 Biliverdin reductase A chr7 Not Cancer Driver No 1 hippie 27 6 1 1 0
BRSK1-201 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 Not Cancer Driver No 1 hippie, biogrid 92 461 53 53 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 16 16 0
BTK-201 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 109 114 21 21 83
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 3 intact, hippie 14 103 5 5 2
CAD-201 CAD P27708 CAD protein chr2 Not Cancer Driver No 1 intact, hippie 211 368 27 27 1
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 28 245 16 16 0
CALU-201 CALU O43852 Calumenin chr7 Not Cancer Driver No 2 intact, hippie, biogrid 15 130 9 9 0
CAMSAP3-201 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 Not Cancer Driver No 1 intact, hippie 98 891 62 62 0
CAND1-208 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 118 88 6 6 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie, biogrid 57 334 36 36 0
CAP1-206 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 39 157 11 11 0
CASP3-201 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 19 64 1 1 0
CASP6-201 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 19 24 4 4 0
CASP7-203 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 28 75 7 7 0
CASP8-218 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 116 106 11 11 1
CASP9-201 CASP9 P55211 Caspase-9 chr1 Census Yes 1 hippie 26 71 7 7 0
CAVIN1-201 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 Not Cancer Driver No 1 hippie 48 281 34 34 0
CAVIN2-201 CAVIN2 O95810 Caveolae-associated protein 2 chr2 Not Cancer Driver No 1 hippie 93 396 86 86 0
CCDC115-201 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 Not Cancer Driver No 1 intact, hippie 18 89 8 8 2
CCT2-201 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 hippie 51 46 4 4 0
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie 65 72 8 8 1
CCT6A-201 CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie 54 5 1 1 0
CD44-208 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 58 547 50 50 0
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 2 intact, hippie 43 214 29 29 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDC42BPB-201 CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 2 hippie, biogrid 148 697 74 74 2
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 26 1 0 0 0
CFL1-201 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie 17 4 0 0 0
CHAT-201 CHAT P28329 Choline O-acetyltransferase chr10 Not Cancer Driver No 1 hippie 126 198 16 16 10
CHCHD2-201 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 10 114 7 7 1
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie 44 412 36 36 0
CLTC-201 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 132 71 5 5 1
COPB1-202 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 74 95 6 6 1
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 13 5 1 1 1
CPSF6-202 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 15 485 9 9 0
CPT1A-201 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 Not Cancer Driver No 1 intact, hippie 115 65 10 10 15
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie, biogrid 38 13 2 2 0
CSE1L-201 CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 77 32 4 4 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 intact, hippie 47 75 6 6 4
CSNK2A3-201 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 Not Cancer Driver No 1 intact, hippie 47 76 9 9 0
CSNK2B-203 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 18 19 0 0 3
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 8
CYCS-201 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 intact, hippie, biogrid 10 20 2 2 1
DAPK3-202 DAPK3 O43293 Death-associated protein kinase 3 chr19 Not Cancer Driver No 1 hippie 45 82 6 6 0
DCAF1-203 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 1 intact, hippie 66 495 21 21 0
DDA1-201 DDA1 Q9BW61 DET1- and DDB1-associated protein 1 chr19 Not Cancer Driver No 1 intact, hippie 6 70 6 6 0
DDB1-201 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact 98 50 8 8 3
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact, hippie, biogrid 20 13 3 3 1
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 91 302 32 32 18
DENND5A-201 DENND5A Q6IQ26 DENN domain-containing protein 5A chr11 Not Cancer Driver No 1 intact, hippie 105 232 17 17 0
DLG4-202 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 5 intact 74 233 34 34 0
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 29 154 13 13 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 34 174 18 18 0
DNAJC13-201 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 hippie 190 142 13 13 0
DYNLL1-201 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 intact, hippie 8 0 0 0 0
ECHS1-201 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 31 7 1 1 14
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie 98 100 10 10 0
EEF1B2-203 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie 22 71 7 7 0
EEF1D-246 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 hippie 30 153 20 20 0
EEF1G-201 EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 36 67 6 6 0
EEF2-201 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 86 79 9 9 1
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF3B-201 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 1 hippie 72 229 5 5 0
EIF3E-201 EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie 59 27 2 2 0
EIF3H-209 EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 hippie 24 109 7 7 0
EIF3L-215 EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 hippie 45 41 1 1 0
EIF4A1-201 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 1 hippie 32 35 4 4 0
EIF5A-202 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 29 21 3 3 5
ENST00000621281 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 38 2 2 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EPB41L4B-202 EPB41L4B Q9H329 Band 4.1-like protein 4B chr9 Not Cancer Driver No 1 intact, hippie 84 548 57 57 0
EPHB4-201 EPHB4 P54760 Ephrin type-B receptor 4 chr7 Not Cancer Driver No 1 biogrid 101 186 18 18 11
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
EZR-202 EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie, biogrid 51 296 26 26 0
F11R-202 F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie 42 72 12 12 0
FADD-201 FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 24 45 9 9 1
FARP2-201 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 100 252 29 29 0
FASN-201 FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 241 310 33 33 0
FAT1-201 FAT1 Q14517 Protocadherin Fat 1 chr4 Census, Compendium Yes 1 hippie 432 1060 85 85 0
FBL-201 FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 1 intact, hippie 21 145 3 3 0
FEZ1-201 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 Not Cancer Driver No 1 hippie 47 278 37 37 0
FEZ2-204 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 Not Cancer Driver No 1 hippie 11 248 6 6 0
FKBP3-202 FKBP3 Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 21 131 14 14 0
FKBP4-201 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 39 134 11 11 0
FLNA-202 FLNA P21333 Filamin-A chrX Census Yes 1 hippie 314 1460 162 162 29
FLNC-201 FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 436 1451 234 234 7
FRS2-206 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 1 hippie 54 417 46 46 0
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 64 71 11 11 0
GABARAP-201 GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 7 12 0 0 0
GANAB-202 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 intact, hippie, biogrid 91 133 17 17 3
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 36 24 3 3 0
GART-203 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 66 50 4 4 0
GDI2-203 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie, biogrid 34 23 1 1 0
GID8-201 GID8 Q9NWU2 Glucose-induced degradation protein 8 homolog chr20 Not Cancer Driver No 1 hippie 23 60 5 5 0
GLG1-202 GLG1 Q92896 Golgi apparatus protein 1 chr16 Not Cancer Driver No 1 intact, hippie 97 103 4 4 0
GLO1-201 GLO1 Q04760 Lactoylglutathione lyase chr6 Not Cancer Driver No 1 hippie, biogrid 18 46 5 5 0
GLRX3-201 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie 32 24 1 1 0
GNB2-201 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 30 21 0 0 5
GOT2-201 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 45 25 3 3 1
GPI-201 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 2 intact, hippie, biogrid 56 73 10 10 23
GPX1-202 GPX1 P07203 Glutathione peroxidase 1 chr3 Not Cancer Driver No 1 biogrid 22 12 3 3 0
GRB14-201 GRB14 Q14449 Growth factor receptor-bound protein 14 chr2 Not Cancer Driver No 1 hippie 58 117 7 7 0
GRM5-202 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 Not Cancer Driver No 2 intact, hippie 228 324 34 34 0
GRWD1-201 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 32 188 9 9 0
GSK3A-201 GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 33 180 5 5 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 2 intact, hippie 34 148 6 6 0
GSN-204 GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie 51 318 18 18 1
GTF3C5-202 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 Not Cancer Driver No 1 hippie 54 157 17 17 0
HABP4-201 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie 21 415 21 21 0
HADHA-201 HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 52 19 0 0 5
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 54 41 9 9 12
HDAC6-201 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 122 409 35 35 0
HINT1-201 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 7 6 0 0 7
HMGB1-203 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 10 202 7 7 0
HMGB2-201 HMGB2 P26583 High mobility group protein B2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 26 207 26 26 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HPRT1-201 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX Not Cancer Driver No 1 intact, hippie, biogrid 19 3 0 0 57
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact, hippie 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 70 255 29 29 0
HSP90B1-201 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 intact, hippie, biogrid 56 269 17 17 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 19 200 7 7 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 49 282 26 26 0
HSPA6-201 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 92 237 23 23 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 82 252 28 28 0
HSPA9-201 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 47 284 19 19 2
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 2 intact, hippie 10 118 8 8 19
HSPE1-201 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 6 3 0 0 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IKBKB-216 IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 hippie 83 211 22 22 1
IL4R-202 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 Not Cancer Driver No 1 hippie 105 426 48 48 0
IMMT-204 IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 75 402 39 39 0
IPO5-230 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 82 52 2 2 0
IRAK1-203 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 hippie 60 338 35 35 0
IRS1-201 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 118 1075 104 104 2
IRS4-202 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie 98 801 80 80 0
ITSN2-201 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 intact, hippie 92 681 33 33 0
JAK1-201 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 hippie 109 120 6 6 2
KBTBD7-201 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 1 hippie, biogrid 63 107 6 6 0
KCTD17-202 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 1 hippie 18 176 10 10 1
KCTD2-201 KCTD2 Q14681 BTB/POZ domain-containing protein KCTD2 chr17 Not Cancer Driver No 1 hippie 27 129 9 9 0
KCTD5-201 KCTD5 Q9NXV2 BTB/POZ domain-containing protein KCTD5 chr16 Not Cancer Driver No 1 hippie 18 32 3 3 0
KEAP1-201 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 217 57 7 7 0
KHSRP-201 KHSRP Q92945 Far upstream element-binding protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 68 684 65 65 0
KIF11-201 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 hippie 60 390 22 22 4
KIF5B-201 KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 intact, hippie, biogrid 88 586 47 47 0
KRT10-201 KRT10 P13645 Keratin, type I cytoskeletal 10 chr17 Not Cancer Driver No 1 hippie 33 297 13 13 10
LGALS1-201 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie 15 0 0 0 0
LLGL1-201 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 4 hippie, biogrid 78 266 9 9 0
LLGL2-203 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 5 intact, hippie, biogrid 98 266 15 15 0
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 99 18 0 0 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MAP1B-201 MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 hippie 169 1949 166 166 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 4 17 0 0 0
MAP2K1-201 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 83 96 22 22 5
MAP2K4-201 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 Census, Compendium Yes 1 hippie, biogrid 72 137 23 23 0
MAP2K5-201 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 hippie 26 85 6 6 0
MAP3K10-201 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 Not Cancer Driver No 1 biogrid 84 591 45 45 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPK15-201 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 Not Cancer Driver No 1 hippie, biogrid 66 236 32 32 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MAPK7-204 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 hippie 56 490 31 31 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 2 hippie, biogrid 5 328 5 5 0
MARCKSL1-201 MARCKSL1 P49006 MARCKS-related protein chr1 Not Cancer Driver No 1 intact, hippie, biogrid 16 195 16 16 0
MBP-202 MBP P02686 Myelin basic protein chr18 Not Cancer Driver No 1 hippie 26 309 26 26 0
MDH1-201 MDH1 P40925 Malate dehydrogenase, cytoplasmic chr2 Not Cancer Driver No 1 hippie, biogrid 32 18 1 1 1
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 26 8 1 1 3
MLKL-202 MLKL Q8NB16 Mixed lineage kinase domain-like protein chr16 Not Cancer Driver No 1 intact, hippie, biogrid 36 89 10 10 0
MMP25-201 MMP25 Q9NPA2 Matrix metalloproteinase-25 chr16 Not Cancer Driver No 1 biogrid 41 245 16 16 0
MRPL1-201 MRPL1 Q9BYD6 Large ribosomal subunit protein uL1m chr4 Not Cancer Driver No 1 hippie 28 46 1 1 0
MRPL12-201 MRPL12 P52815 Large ribosomal subunit protein bL12m chr17 Not Cancer Driver No 2 intact, hippie 16 22 4 4 1
MRPL18-201 MRPL18 Q9H0U6 Large ribosomal subunit protein uL18m chr6 Not Cancer Driver No 1 hippie 19 35 3 3 0
MRPL19-202 MRPL19 P49406 Large ribosomal subunit protein bL19m chr2 Not Cancer Driver No 1 hippie 14 64 2 2 0
MRPL37-202 MRPL37 Q9BZE1 Large ribosomal subunit protein mL37 chr1 Not Cancer Driver No 1 hippie 33 36 3 3 0
MRPL38-201 MRPL38 Q96DV4 Large ribosomal subunit protein mL38 chr17 Not Cancer Driver No 1 hippie 36 90 13 13 0
MRPL39-202 MRPL39 Q9NYK5 Large ribosomal subunit protein mL39 chr21 Not Cancer Driver No 1 hippie 25 38 2 2 0
MRPL45-203 MRPL45 Q9BRJ2 Large ribosomal subunit protein mL45 chr17 Not Cancer Driver No 1 hippie 23 62 5 5 0
MRPL46-201 MRPL46 Q9H2W6 Large ribosomal subunit protein mL46 chr15 Not Cancer Driver No 1 hippie 16 59 0 0 0
MRPL48-201 MRPL48 Q96GC5 Large ribosomal subunit protein mL48 chr11 Not Cancer Driver No 1 hippie 10 15 0 0 0
MRPL49-201 MRPL49 Q13405 Large ribosomal subunit protein mL49 chr11 Not Cancer Driver No 1 hippie 14 74 7 7 0
MRPL50-201 MRPL50 Q8N5N7 Large ribosomal subunit protein mL50 chr9 Not Cancer Driver No 1 hippie 22 3 0 0 0
MRPL52-202 MRPL52 Q86TS9 Large ribosomal subunit protein mL52 chr14 Not Cancer Driver No 1 hippie 7 75 5 5 0
MRPL53-201 MRPL53 Q96EL3 Large ribosomal subunit protein mL53 chr2 Not Cancer Driver No 2 intact, hippie 19 22 1 1 0
MRPL54-201 MRPL54 Q6P161 Large ribosomal subunit protein mL54 chr19 Not Cancer Driver No 1 hippie 15 54 4 4 0
MRPL55-203 MRPL55 Q7Z7F7 Large ribosomal subunit protein mL55 chr1 Not Cancer Driver No 1 hippie 14 67 9 9 0
MRPS2-201 MRPS2 Q9Y399 Small ribosomal subunit protein uS2m chr9 Not Cancer Driver No 1 intact, hippie 26 57 4 4 3
MSH2-201 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 hippie 55 37 1 1 63
MSH6-201 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 Census Yes 1 hippie 92 389 26 26 6
MTHFD1-220 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 intact, hippie, biogrid 78 129 11 11 6
MYCBP-201 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 55 4 4 0
NAP1L1-226 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 2 intact, hippie 31 207 18 18 0
NAP1L4-201 NAP1L4 Q99733 Nucleosome assembly protein 1-like 4 chr11 Not Cancer Driver No 1 intact, hippie 18 194 7 7 0
NASP-201 NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 intact, hippie, biogrid 61 618 53 53 0
NCF1-201 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 2 intact, hippie 31 181 11 11 1
NCL-201 NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 32 569 20 20 0
NCOA3-202 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 Not Cancer Driver No 1 hippie 134 1231 119 119 0
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NFATC2-202 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie 144 726 124 124 0
NIPSNAP1-201 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 26 9 0 0 0
NIPSNAP2-201 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 Not Cancer Driver No 3 intact, hippie 24 6 1 1 0
NMT2-202 NMT2 O60551 Glycylpeptide N-tetradecanoyltransferase 2 chr10 Not Cancer Driver No 1 intact, hippie 39 155 15 15 0
NOC2L-201 NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie 54 281 22 22 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 2 intact, hippie 25 249 19 19 0
NPM3-201 NPM3 O75607 Nucleoplasmin-3 chr10 Not Cancer Driver No 2 intact, hippie 18 78 7 7 0
NR5A1-202 NR5A1 Q13285 Steroidogenic factor 1 chr9 Not Cancer Driver No 1 biogrid 42 135 18 18 23
NSRP1-201 NSRP1 Q9H0G5 Nuclear speckle splicing regulatory protein 1 chr17 Not Cancer Driver No 1 hippie 43 524 41 41 0
NUMB-213 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie 50 489 42 42 0
OAT-201 OAT P04181 Ornithine aminotransferase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 38 17 0 0 26
OLA1-201 OLA1 Q9NTK5 Obg-like ATPase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 33 40 3 3 0
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 41 80 13 13 1
PA2G4-201 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 36 128 12 12 0
PAICS-207 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 intact, hippie, biogrid 16 35 1 1 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 36 300 19 19 2
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 2 intact, hippie 148 1147 128 128 2
PARD6A-201 PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 Not Cancer Driver No 8 intact, hippie, biogrid 23 178 11 11 0
PARD6B-201 PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 10 intact, hippie, biogrid 41 166 18 18 0
PARD6G-201 PARD6G Q9BYG4 Partitioning defective 6 homolog gamma chr18 Not Cancer Driver No 8 intact, hippie, biogrid 28 176 10 10 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 8 30 0 0 6
PAWR-201 PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 Not Cancer Driver No 1 hippie 23 328 22 22 0
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie, biogrid 19 22 2 2 1
PDCD5-207 PDCD5 O14737 Programmed cell death protein 5 chr19 Not Cancer Driver No 1 hippie, biogrid 13 91 7 7 0
PDIA3-201 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie, biogrid 34 98 6 6 0
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PDIA6-201 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 41 82 8 8 0
PDLIM7-202 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 30 247 14 14 0
PDPK1-202 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 hippie 23 121 9 9 0
PEBP1-201 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 17 77 11 11 0
PFKP-203 PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 Not Cancer Driver No 1 intact, hippie, biogrid 84 43 4 4 0
PFN1-201 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 13 7 1 1 3
PGD-201 PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 intact, hippie, biogrid 50 19 2 2 0
PGK1-201 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 44 40 3 3 9
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 23 74 11 11 0
PIAS4-201 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 40 143 18 18 0
PKD1-201 PKD1 P98161 Polycystin-1 chr16 Not Cancer Driver No 1 intact, hippie 299 695 50 50 91
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
POLD1-201 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 118 210 17 17 2
POLRMT-202 POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 117 258 25 25 6
PPA1-202 PPA1 Q15181 Inorganic pyrophosphatase chr10 Not Cancer Driver No 1 hippie, biogrid 22 24 0 0 0
PPFIBP1-202 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie 72 557 42 42 0
PPIA-204 PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 9 24 1 1 0
PPIF-201 PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie, biogrid 13 44 2 2 0
PPIL4-201 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 Not Cancer Driver No 1 hippie 40 237 23 23 0
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 19 23 3 3 0
PPP1R14A-201 PPP1R14A Q96A00 Protein phosphatase 1 regulatory subunit 14A chr19 Not Cancer Driver No 1 hippie 10 114 8 8 0
PPP2CA-203 PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 32 12 1 1 7
PPP3CA-203 PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 1 hippie 63 140 24 24 7
PRDX1-202 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 23 40 7 7 0
PRDX3-201 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 17 23 2 2 2
PRDX4-202 PRDX4 Q13162 Peroxiredoxin-4 chrX Not Cancer Driver No 2 intact, hippie, biogrid 31 29 2 2 0
PRDX6-201 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 32 13 3 3 0
PRG2-201 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie 37 66 13 13 0
PRKACA-201 PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 intact, hippie 49 24 0 0 2
PRKACB-205 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 intact, hippie 35 26 2 2 3
PRKAR1A-216 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 26 66 5 5 15
PRKCA-202 PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 2 hippie, biogrid 70 155 17 17 0
PRKCD-201 PRKCD Q05655 Protein kinase C delta type chr3 Compendium Yes 2 hippie, biogrid 52 43 7 7 0
PRKCE-201 PRKCE Q02156 Protein kinase C epsilon type chr2 Not Cancer Driver No 1 biogrid 80 170 16 16 0
PRKCH-201 PRKCH P24723 Protein kinase C eta type chr14 Not Cancer Driver No 1 biogrid 66 92 10 10 0
PRKCI-201 PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 5 hippie, biogrid 79 120 12 12 0
PRKCQ-201 PRKCQ Q04759 Protein kinase C theta type chr10 Not Cancer Driver No 1 intact, hippie 124 28 8 8 0
PRKCSH-209 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 47 320 28 28 0
PRKCZ-201 PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie 47 117 11 11 0
PRKD1-201 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 164 190 31 31 2
PRPSAP2-201 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 Not Cancer Driver No 1 hippie 39 20 3 3 0
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 hippie 43 134 18 18 69
PSMC4-201 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 1 hippie 38 21 2 2 0
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 35 64 5 5 0
PSMD1-201 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 77 201 14 14 0
PSME3-210 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 16 25 5 5 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 52 2 2 0
PTPN14-201 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie 130 584 79 79 0
PTPRZ1-201 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 Not Cancer Driver No 1 biogrid 321 980 142 142 0
RACK1-227 RACK1 P63244 Small ribosomal subunit protein RACK1 chr5 Not Cancer Driver No 1 intact, hippie 27 13 0 0 0
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie 64 169 30 30 18
RALGDS-202 RALGDS Q12967 Ral guanine nucleotide dissociation stimulator chr9 Census, Compendium Yes 1 hippie 72 382 28 28 0
RCN2-203 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 intact, hippie 27 125 7 7 0
RELA-202 RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 53 401 32 32 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 2 hippie, biogrid 92 46 12 12 2
RICTOR-202 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 intact, hippie 144 365 34 34 0
RIPK1-201 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 59 277 28 28 1
RNF146-202 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 Not Cancer Driver No 1 hippie 23 206 15 15 0
RNH1-201 RNH1 P13489 Ribonuclease inhibitor chr11 Not Cancer Driver No 1 hippie 32 0 0 0 0
RPLP1-201 RPLP1 P05386 Large ribosomal subunit protein P1 chr15 Not Cancer Driver No 1 hippie 5 45 1 1 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
RPS12-201 RPS12 P25398 Small ribosomal subunit protein eS12 chr6 Not Cancer Driver No 1 hippie 13 0 0 0 0
RPS6KB1-201 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 Not Cancer Driver No 1 hippie 36 226 22 22 0
RPUSD4-201 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 44 98 15 15 0
SDHA-201 SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact, hippie, biogrid 87 72 9 9 7
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 intact, hippie, biogrid 6 60 5 5 0
SHMT2-201 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie, biogrid 45 58 4 4 1
SLC16A1-201 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 Not Cancer Driver No 1 hippie, biogrid 52 70 4 4 3
SLC1A5-203 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie, biogrid 42 61 7 7 0
SLC25A1-201 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie, biogrid 17 34 1 1 15
SLC25A3-215 SLC25A3 Q00325 Solute carrier family 25 member 3 chr12 Not Cancer Driver No 2 intact, hippie 31 32 4 4 1
SLC25A4-201 SLC25A4 P12235 ADP/ATP translocase 1 chr4 Not Cancer Driver No 1 intact, hippie 18 0 0 0 9
SLC25A5-201 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 2 intact, hippie 26 0 0 0 0
SLC25A6-201 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie 29 0 0 0 0
SLC35G1-202 SLC35G1 Q2M3R5 Solute carrier family 35 member G1 chr10 Not Cancer Driver No 1 intact, hippie 21 36 0 0 0
SLC39A1-202 SLC39A1 Q9NY26 Zinc transporter ZIP1 chr1 Not Cancer Driver No 1 hippie 33 22 0 0 0
SLFN11-214 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 125 34 7 7 0
SND1-201 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 97 258 33 33 0
SNRPD1-201 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 hippie 4 80 0 0 0
SNRPD2-201 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 hippie 16 67 8 8 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 14 94 9 9 57
SP1-201 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 67 601 53 53 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 7 intact, hippie, biogrid 41 271 24 24 30
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 2 hippie, biogrid 40 130 10 10 1
STAT6-201 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 Census, Compendium Yes 1 hippie 86 325 39 39 0
STK24-201 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 42 118 13 13 0
STK38-201 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie 36 78 4 4 0
STT3A-201 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie, biogrid 60 27 1 1 4
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 29 113 11 11 11
SUB1-201 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie, biogrid 8 108 4 4 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie, biogrid 8 70 6 6 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 hippie 62 233 23 23 0
TARS1-201 TARS1 P26639 Threonine--tRNA ligase 1, cytoplasmic chr5 Not Cancer Driver No 1 intact 84 112 16 16 2
TBCB-201 TBCB Q99426 Tubulin-folding cofactor B chr19 Not Cancer Driver No 1 hippie, biogrid 23 59 1 1 0
TECR-201 TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 intact, hippie, biogrid 33 0 0 0 1
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 1 hippie 263 813 147 147 0
TIMM50-219 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 intact, hippie 29 75 4 4 0
TKT-207 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 intact, hippie, biogrid 44 86 5 5 1
TLR4-201 TLR4 O00206 Toll-like receptor 4 chr9 Not Cancer Driver No 1 hippie 253 0 0 0 0
TLR9-201 TLR9 Q9NR96 Toll-like receptor 9 chr3 Not Cancer Driver No 1 hippie 107 35 3 3 0
TMEM160-201 TMEM160 Q9NX00 Transmembrane protein 160 chr19 Not Cancer Driver No 1 hippie, biogrid 3 46 0 0 0
TPR-201 TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 215 1994 184 184 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TRAP1-201 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 51 110 6 6 0
TRIM21-201 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 63 49 8 8 0
TRIM26-268 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 1 intact, hippie 38 153 5 5 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 intact, hippie 67 431 32 32 0
TRIM41-201 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 44 388 19 19 0
TUBA1C-201 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie 26 50 2 2 0
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie 50 39 2 2 4
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 29 63 5 5 5
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 51 54 6 6 10
TUBB4A-201 TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 hippie 65 61 5 5 2
TUBB4B-201 TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 43 65 7 7 1
TUBB6-201 TUBB6 Q9BUF5 Tubulin beta-6 chain chr18 Not Cancer Driver No 2 intact, hippie 57 52 4 4 1
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 36 51 4 4 1
TXNDC5-201 TXNDC5 Q8NBS9 Thioredoxin domain-containing protein 5 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 32 104 7 7 0
UBA1-201 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie, biogrid 82 166 14 14 4
UBA2-201 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 62 221 22 22 4
UBE2O-201 UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 intact, hippie 94 717 54 54 0
UCHL1-201 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 23 34 5 5 4
UQCRC1-201 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 41 55 3 3 2
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 31 48 5 5 1
USP20-203 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie 87 296 30 30 0
UTP14A-201 UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie 63 629 56 56 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 25 36 4 4 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 22 9 1 1 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 85 117 15 15 84
WDR26-214 WDR26 Q9H7D7 WD repeat-containing protein 26 chr1 Not Cancer Driver No 1 hippie 47 187 7 7 0
WWC1-201 WWC1 Q8IX03 Protein KIBRA chr5 Not Cancer Driver No 3 intact, hippie, biogrid 120 555 70 70 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie, biogrid 84 33 5 5 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 intact, hippie 19 110 3 3 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 1 hippie 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 19 81 7 7 0
ZNF71-201 ZNF71 Q9NQZ8 Endothelial zinc finger protein induced by tumor necrosis factor alpha chr19 Not Cancer Driver No 1 intact, hippie 105 179 36 36 0