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PROX1-201 ,PROX1 ,Q92786
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 6
  • Number of Interaction partner in hippie: 39
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BRD3-201 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 64 567 53 53 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BRPF3-202 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 Not Cancer Driver No 1 hippie 104 633 49 49 0
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 20 192 18 18 0
CCL26-201 CCL26 Q9Y258 C-C motif chemokine 26 chr7 Not Cancer Driver No 1 intact 6 0 0 0 0
CEBPZ-201 CEBPZ Q03701 CCAAT/enhancer-binding protein zeta chr2 Not Cancer Driver No 1 hippie 64 492 33 33 0
CHD4-206 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 312 978 118 118 6
CREBBP-201 CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 217 1801 91 91 30
CTBP1-201 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 30 123 8 8 1
CTBP2-205 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 intact, hippie 36 94 4 4 0
CYP7A1-201 CYP7A1 P22680 Cytochrome P450 7A1 chr8 Not Cancer Driver No 1 intact 71 48 4 4 0
CYTH4-201 CYTH4 Q9UIA0 Cytohesin-4 chr22 Not Cancer Driver No 1 hippie, biogrid 52 54 9 9 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
ESRRA-201 ESRRA P11474 Steroid hormone receptor ERR1 chr11 Compendium Yes 1 hippie 27 101 9 9 0
ESRRG-209 ESRRG P62508 Estrogen-related receptor gamma chr1 Not Cancer Driver No 2 hippie, biogrid 112 77 20 20 0
FGF11-201 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie 13 68 2 2 0
GIT2-202 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 1 hippie 59 494 36 36 0
HDAC2-205 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 intact, hippie 34 145 11 11 0
HDAC3-201 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 intact, hippie 42 61 5 5 0
HNF1A-201 HNF1A P20823 Hepatocyte nuclear factor 1-alpha chr12 Census, Compendium Yes 1 hippie 83 567 66 66 38
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 113 127 44 44 5
IL18-201 IL18 Q14116 Interleukin-18 chr11 Not Cancer Driver No 1 intact 11 16 2 2 0
IRF4-201 IRF4 Q15306 Interferon regulatory factor 4 chr6 Census, Compendium Yes 1 hippie 85 155 42 42 0
LBH-201 LBH Q53QV2 Protein LBH chr2 Not Cancer Driver No 1 intact, hippie 11 72 7 7 0
MBD3L2-201 MBD3L2 Q8NHZ7 Methyl-CpG-binding domain protein 3-like 2 chr19 Not Cancer Driver No 1 hippie, biogrid 6 188 6 6 0
MKRN2-201 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 30 145 7 7 0
NR3C2-203 NR3C2 P08235 Mineralocorticoid receptor chr4 Not Cancer Driver No 1 hippie 120 487 63 63 14
NR5A1-202 NR5A1 Q13285 Steroidogenic factor 1 chr9 Not Cancer Driver No 1 hippie 42 135 18 18 23
NR5A2-203 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 Not Cancer Driver No 1 hippie 99 155 28 28 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
PAX6-203 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 51 338 37 37 35
PPARD-203 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie 51 70 5 5 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 60 44 3 3 3
PROX1-201 PROX1 Q92786 Prospero homeobox protein 1 chr1 Not Cancer Driver No 1 hippie 151 539 116 116 0
RBBP4-202 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie, biogrid 40 169 19 19 0
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 Not Cancer Driver No 1 hippie 43 181 11 11 4
S100A2-202 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 6 0 0 0
S100P-201 S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie, biogrid 3 3 1 1 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 80 113 15 15 5
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
TNFSF4-201 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 Not Cancer Driver No 1 intact 17 1 0 0 0
TRIM66-208 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 32 773 20 20 0
ZBTB3-204 ZBTB3 Q9H5J0 Zinc finger and BTB domain-containing protein 3 chr11 Not Cancer Driver No 1 intact, hippie 61 353 31 31 0