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PTGS2-201 ,PTGS2 ,P35354
  • Number of Interaction partner in intact: 8
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 37
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGTR1-201 AGTR1 P30556 Type-1 angiotensin II receptor chr3 Not Cancer Driver No 1 hippie 70 0 0 0 1
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ATN1-202 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact 111 1176 109 109 5
CASK-203 CASK O14936 Peripheral plasma membrane protein CASK chrX Not Cancer Driver No 1 intact, hippie 80 285 27 27 4
CASP8-218 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 intact 116 106 11 11 1
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 23 2 0 0 0
CELF2-209 CELF2 O95319 CUGBP Elav-like family member 2 chr10 Not Cancer Driver No 1 hippie 55 171 21 21 1
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
COPS3-201 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 hippie 36 67 7 7 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
COPS7A-215 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 Not Cancer Driver No 1 hippie 25 74 8 8 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CUL1-201 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 127 65 9 9 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 54 102 2 2 0
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie 17 12 0 0 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ELMO1-201 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 Not Cancer Driver No 1 hippie 158 98 21 21 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 36 171 11 11 0
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 intact, hippie 38 125 16 16 0
HNRNPD-201 HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 28 206 12 12 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 50 352 21 21 0
LMAN2L-201 LMAN2L Q9H0V9 VIP36-like protein chr2 Not Cancer Driver No 1 intact, hippie, biogrid 36 17 1 1 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
NUCB1-201 NUCB1 Q02818 Nucleobindin-1 chr19 Not Cancer Driver No 1 hippie 45 352 34 34 0
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 35 64 5 5 0
PSMD1-201 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 77 201 14 14 0
PTGER1-201 PTGER1 P34995 Prostaglandin E2 receptor EP1 subtype chr19 Not Cancer Driver No 1 hippie 3 26 0 0 0
PTGIS-201 PTGIS Q16647 Prostacyclin synthase chr20 Not Cancer Driver No 1 hippie 81 18 2 2 0
PTGS1-202 PTGS1 P23219 Prostaglandin G/H synthase 1 chr9 Not Cancer Driver No 1 hippie 92 28 3 3 0
PTGS2-201 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 Not Cancer Driver No 2 intact, hippie 68 31 4 4 0
RBX1-201 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 9 18 1 1 0
SELENOS-203 SELENOS Q9BQE4 Selenoprotein S chr15 Not Cancer Driver No 1 hippie 4 123 3 3 0
SKP2-202 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 37 52 5 5 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TP53BP1-201 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 159 1638 131 131 0
USP22-201 USP22 Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 chr17 Not Cancer Driver No 1 hippie 42 50 1 1 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12