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PTPN14-201 ,PTPN14 ,Q15678
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 49
  • Number of Interaction partner in hippie: 147
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD11-201 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 77 33 5 5 0
ACAD8-201 ACAD8 Q9UKU7 Isobutyryl-CoA dehydrogenase, mitochondrial chr11 Not Cancer Driver No 1 hippie 41 13 0 0 9
AFDN-211 AFDN P55196 Afadin chr6 Census Yes 1 hippie 162 1247 123 123 0
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie 41 109 11 11 0
AMMECR1L-201 AMMECR1L Q6DCA0 AMMECR1-like protein chr2 Not Cancer Driver No 1 hippie 31 84 6 6 0
AMOT-203 AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 2 hippie, biogrid 103 911 85 85 0
ANKRD50-201 ANKRD50 Q9ULJ7 Ankyrin repeat domain-containing protein 50 chr4 Not Cancer Driver No 1 hippie 160 434 55 55 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
ARMC8-210 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 42 7 0 0 0
ATE1-201 ATE1 O95260 Arginyl-tRNA--protein transferase 1 chr10 Not Cancer Driver No 1 hippie 27 189 10 10 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BICD1-210 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 105 661 70 70 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 83 546 51 51 10
BPIFB1-201 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 Not Cancer Driver No 1 hippie 69 7 0 0 0
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
CBY1-201 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 1 hippie 9 98 7 7 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CGN-201 CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 hippie 113 1182 111 111 0
COPS4-201 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 Not Cancer Driver No 1 hippie 35 13 0 0 0
CPS1-201 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie 300 73 18 18 123
CRLF3-201 CRLF3 Q8IUI8 Cytokine receptor-like factor 3 chr17 Not Cancer Driver No 1 hippie 34 80 5 5 0
CSNK1D-202 CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 hippie 38 133 13 13 2
CTDSPL-201 CTDSPL O15194 CTD small phosphatase-like protein chr3 Not Cancer Driver No 1 hippie 26 60 2 2 0
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie 90 268 25 25 4
CTNNA2-203 CTNNA2 P26232 Catenin alpha-2 chr2 Census Yes 1 hippie 328 308 108 108 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CUL2-203 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 hippie 64 66 2 2 0
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
DCLK1-202 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 1 hippie 148 253 49 49 0
DENND1A-203 DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 98 591 63 63 0
DENND4C-209 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 1 hippie 121 709 40 40 0
DNAJC5-201 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 19 46 5 5 1
EBAG9-201 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 27 175 25 25 0
EIF4E2-201 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 1 hippie 24 80 5 5 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EZR-202 EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 51 296 26 26 0
FAM120C-202 FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 127 511 66 66 0
FLOT1-201 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 122 10 10 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GIGYF1-207 GIGYF1 O75420 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 1 hippie 111 860 94 94 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GPS1-201 GPS1 Q13098 COP9 signalosome complex subunit 1 chr17 Not Cancer Driver No 1 hippie 53 106 10 10 0
HAX1-201 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 219 23 23 2
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 145 751 95 95 3
HECTD1-201 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie 210 992 85 85 0
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 45 83 1 1 2
INPP5E-201 INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 Not Cancer Driver No 1 hippie 32 273 9 9 15
JPH4-201 JPH4 Q96JJ6 Junctophilin-4 chr14 Not Cancer Driver No 2 hippie, biogrid 48 517 47 47 0
JUP-203 JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 81 242 24 24 0
KCNE3-201 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
KCTD3-201 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 1 hippie 90 326 39 39 0
KIF13B-206 KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 Not Cancer Driver No 1 hippie 131 970 56 56 0
KIF2A-202 KIF2A O00139 Kinesin-like protein KIF2A chr5 Not Cancer Driver No 1 hippie 47 336 22 22 2
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 771 7 2 2 22
KRT13-201 KRT13 P13646 Keratin, type I cytoskeletal 13 chr17 Not Cancer Driver No 1 hippie 54 181 22 22 6
KRT8-218 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 49 225 23 23 3
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 88 408 46 46 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 2 hippie, biogrid 122 790 74 74 0
LATS2-201 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 101 690 57 57 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 76 95 12 12 1
LIMA1-201 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 64 688 60 60 0
LRFN1-201 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 77 278 31 31 0
LRR1-201 LRR1 Q96L50 Leucine-rich repeat protein 1 chr14 Not Cancer Driver No 1 hippie 30 3 1 1 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
MAEA-202 MAEA Q7L5Y9 E3 ubiquitin-protein transferase MAEA chr4 Not Cancer Driver No 1 hippie 50 64 5 5 0
MAGI1-202 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 3 hippie, biogrid 173 1181 140 140 0
MAGI3-201 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 Not Cancer Driver No 2 hippie, biogrid 115 1041 83 83 0
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 64 376 38 38 1
MAST3-201 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 1 hippie 133 785 77 77 5
MOB1A-201 MOB1A Q9H8S9 MOB kinase activator 1A chr2 Not Cancer Driver No 1 hippie, biogrid 12 11 0 0 0
MOB1B-201 MOB1B Q7L9L4 MOB kinase activator 1B chr4 Not Cancer Driver No 1 hippie, biogrid 14 7 0 0 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NDEL1-201 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 Not Cancer Driver No 1 hippie 23 203 13 13 0
NF1-202 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 1 hippie 285 406 36 36 75
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 148 1147 128 128 2
PARD6B-201 PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 3 hippie, biogrid 41 166 18 18 0
PDLIM7-202 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 2 hippie, biogrid 30 247 14 14 0
PHF20-203 PHF20 Q9BVI0 PHD finger protein 20 chr20 Not Cancer Driver No 2 hippie, biogrid 100 667 61 61 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
POLE-201 POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 Census, Compendium Yes 1 hippie 234 240 31 31 3
PPM1H-201 PPM1H Q9ULR3 Protein phosphatase 1H chr12 Not Cancer Driver No 1 hippie 60 141 25 25 0
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 169 0 0 0 4
PPP2R2A-202 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 36 68 6 6 0
PRKCZ-201 PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie 47 117 11 11 0
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 425 76 5 5 37
PTPN14-201 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie 130 584 79 79 0
PXN-201 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie, biogrid 41 342 14 14 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RANBP10-201 RANBP10 Q6VN20 Ran-binding protein 10 chr16 Not Cancer Driver No 1 hippie 71 297 39 39 0
RC3H2-202 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 99 704 62 62 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 50 20 1 1 0
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RHPN1-201 RHPN1 Q8TCX5 Rhophilin-1 chr8 Not Cancer Driver No 2 hippie, biogrid 60 257 26 26 0
RMND5A-201 RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 Not Cancer Driver No 1 hippie 26 0 0 0 0
RND3-201 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 23 70 7 7 0
RTKN-202 RTKN Q9BST9 Rhotekin chr2 Not Cancer Driver No 1 hippie 53 265 30 30 0
S100A2-202 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 6 0 0 0
SAMD4B-212 SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 68 467 47 47 0
SAV1-201 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 24 245 13 13 0
SH3PXD2A-203 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 111 802 86 86 0
SIPA1L1-211 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 hippie 231 1176 166 166 0
SOCS7-205 SOCS7 O14512 Suppressor of cytokine signaling 7 chr17 Not Cancer Driver No 1 hippie 33 396 22 22 0
SRGAP2-203 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 98 543 57 57 0
SRSF12-201 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 1 hippie 24 205 20 20 0
STIP1-201 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 54 270 28 28 0
STK3-201 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie 48 241 22 22 0
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 21 165 9 9 0
STXBP4-201 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 2 hippie, biogrid 58 212 20 20 0
SYDE1-201 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 1 hippie 52 412 25 25 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TESK2-202 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 Not Cancer Driver No 1 hippie 57 243 31 31 0
TJP1-201 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie 143 1350 113 113 0
TRIM66-208 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 32 773 20 20 0
TRIP6-201 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 hippie 48 270 14 14 0
USP47-203 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 1 hippie 86 426 24 24 0
USP9X-202 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie 243 405 33 33 1
VASP-201 VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 16 335 11 11 0
VBP1-201 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 1 hippie, biogrid 16 47 5 5 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 85 117 15 15 84
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VPS33A-201 VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 Not Cancer Driver No 1 hippie 63 46 6 6 1
WDR26-214 WDR26 Q9H7D7 WD repeat-containing protein 26 chr1 Not Cancer Driver No 1 hippie 47 187 7 7 0
WWC1-201 WWC1 Q8IX03 Protein KIBRA chr5 Not Cancer Driver No 2 hippie, biogrid 120 555 70 70 0
WWC2-201 WWC2 Q6AWC2 Protein WWC2 chr4 Not Cancer Driver No 1 hippie 84 657 50 50 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
WWP1-202 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 104 432 55 55 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 4 hippie, biogrid 41 491 41 41 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 hippie, biogrid 19 110 3 3 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 10 55 0 0 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 19 81 7 7 0
ZBTB21-201 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 1 hippie 91 649 48 48 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0
ZNF638-201 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 1 hippie 173 1674 153 153 0
ZYX-201 ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 49 385 29 29 0