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PTPN7-220 ,PTPN7 ,P35236
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 66
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AATK-201 AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact, hippie 82 916 59 59 0
ACAD11-201 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 1 hippie 77 33 5 5 0
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie 41 109 11 11 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARMCX3-203 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie 29 77 7 7 0
CCDC57-202 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 79 604 44 44 0
CDH2-201 CDH2 P19022 Cadherin-2 chr18 Not Cancer Driver No 1 intact, hippie 182 464 107 107 7
CYFIP1-208 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 121 95 5 5 0
DCAF10-202 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 1 hippie 33 201 7 7 0
DCAF7-205 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 hippie 19 0 0 0 0
DDX39A-201 DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 36 37 2 2 0
DHPS-201 DHPS P49366 Deoxyhypusine synthase chr19 Not Cancer Driver No 1 intact, hippie 35 70 2 2 1
ECD-201 ECD O95905 Protein ecdysoneless homolog chr10 Not Cancer Driver No 1 hippie 44 257 15 15 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
ENST00000690765 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 hippie 19 0 0 0 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 147 188 33 33 3
ERBB3-201 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 265 398 59 59 3
ERBB4-202 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 intact, hippie 376 324 95 95 2
FUOM-201 FUOM A2VDF0 Fucose mutarotase chr10 Not Cancer Driver No 1 hippie 7 0 0 0 0
GLB1-201 GLB1 P16278 Beta-galactosidase chr3 Not Cancer Driver No 1 hippie 58 44 6 6 89
GMCL1-201 GMCL1 Q96IK5 Germ cell-less protein-like 1 chr2 Not Cancer Driver No 2 intact, hippie 23 80 2 2 0
HSPA1L-201 HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 intact, hippie 86 141 23 23 0
HSPH1-201 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 intact, hippie 69 323 31 31 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 143 265 30 30 6
IPO4-201 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie 78 87 3 3 0
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 99 18 0 0 1
MACROD1-201 MACROD1 Q9BQ69 ADP-ribose glycohydrolase MACROD1 chr11 Not Cancer Driver No 1 hippie 15 45 1 1 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 5 intact, hippie 52 2 0 0 6
MAPK11-201 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie 22 64 2 2 0
MAPK14-201 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 22 25 0 0 0
MAPK1IP1L-201 MAPK1IP1L Q8NDC0 MAPK-interacting and spindle-stabilizing protein-like chr14 Not Cancer Driver No 1 hippie 16 246 16 16 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MAPKAPK3-208 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 Not Cancer Driver No 1 hippie 24 117 8 8 1
ME1-201 ME1 P48163 NADP-dependent malic enzyme chr6 Not Cancer Driver No 1 intact, hippie 84 65 7 7 0
MTA2-201 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie 59 283 25 25 0
OPA1-204 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie 86 131 14 14 58
PAK4-203 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 46 344 27 27 0
PITRM1-201 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 Not Cancer Driver No 1 hippie 70 222 16 16 2
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie 48 23 3 3 4
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie 36 22 2 2 4
PNMA2-204 PNMA2 Q9UL42 Paraneoplastic antigen Ma2 chr8 Not Cancer Driver No 1 hippie 36 45 2 2 0
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 31 27 6 6 0
PPP2CA-203 PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 32 12 1 1 7
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 169 0 0 0 4
PPP2R2A-202 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 36 68 6 6 0
PPP2R2D-201 PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 32 66 6 6 0
PPP6R3-203 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 hippie 77 389 37 37 0
PREPL-206 PREPL Q4J6C6 Prolyl endopeptidase-like chr2 Not Cancer Driver No 1 hippie 89 91 17 17 0
PRKACA-201 PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 49 24 0 0 2
PRMT1-202 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 37 18 0 0 0
PSME3-210 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 16 25 5 5 0
PTK7-202 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 Not Cancer Driver No 1 hippie 113 359 43 43 0
PTOV1-201 PTOV1 Q86YD1 Prostate tumor-overexpressed gene 1 protein chr19 Not Cancer Driver No 1 hippie 41 122 7 7 0
PTPN7-220 PTPN7 P35236 Tyrosine-protein phosphatase non-receptor type 7 chr1 Not Cancer Driver No 1 hippie 39 165 17 17 0
RANBP6-201 RANBP6 O60518 Ran-binding protein 6 chr9 Not Cancer Driver No 1 hippie 99 46 3 3 0
RBBP7-203 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 hippie 42 138 8 8 0
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie 164 304 58 58 5
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
RPS12-201 RPS12 P25398 Small ribosomal subunit protein eS12 chr6 Not Cancer Driver No 1 hippie 13 0 0 0 0
RPS19BP1-201 RPS19BP1 Q86WX3 Active regulator of SIRT1 chr22 Not Cancer Driver No 1 hippie 3 112 3 3 0
SAV1-201 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 24 245 13 13 0
SIRPA-202 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie 60 282 41 41 0
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie 20 0 0 0 6
UBE2O-201 UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie 94 717 54 54 0
UGGT1-201 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 hippie 113 162 14 14 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 hippie 25 42 2 2 0