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RCC2-202 ,RCC2 ,Q9P258
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 134
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ACOT7-204 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 Not Cancer Driver No 1 hippie 29 77 9 9 0
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
AHCY-201 AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 6
AIM2-202 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 54 79 17 17 0
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 16 5 0 0 0
ASH2L-201 ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie 71 294 33 33 0
ATG5-204 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 33 25 6 6 1
AURKB-214 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 31 63 4 4 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
BUD31-201 BUD31 P41223 Protein BUD31 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 14 32 4 4 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDCA8-202 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 hippie 18 171 10 10 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 216 145 9 9 130
CHMP4B-201 CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 21 201 20 20 2
CIC-206 CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 216 1552 207 207 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
COQ2-206 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 16 25 0 0 17
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 41 84 12 12 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 biogrid 47 75 6 6 4
CSNK2A2-201 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 1 biogrid 25 13 1 1 0
CSNK2A3-201 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 Not Cancer Driver No 1 biogrid 47 76 9 9 0
CUL4B-231 CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 83 207 23 23 2
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DEF6-201 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 42 337 4 4 2
DIPK2A-201 DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 Not Cancer Driver No 1 intact, hippie 44 9 0 0 0
DOCK11-201 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX Not Cancer Driver No 1 hippie 222 240 22 22 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF2D-201 EIF2D P41214 Eukaryotic translation initiation factor 2D chr1 Not Cancer Driver No 1 hippie, biogrid 37 143 8 8 0
EIF6-203 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 22 17 2 2 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
EMC4-202 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 8 17 1 1 0
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
ENST00000652248 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 1 hippie, biogrid 14 43 11 11 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
ERG-201 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 68 297 38 38 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
ETV3-202 ETV3 P41162 ETS translocation variant 3 chr1 Not Cancer Driver No 1 intact, hippie 37 330 16 16 0
FAF1-201 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 54 241 23 23 0
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 289 1249 137 137 8
FTSJ1-202 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact, hippie 31 89 8 8 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 55 352 38 38 0
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GDI1-204 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX Not Cancer Driver No 1 hippie 54 34 4 4 2
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 21 10 0 0 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 34 148 6 6 0
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 145 751 95 95 3
HDGF-201 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 intact, hippie 25 203 21 21 0
HLA-B-249 HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 49 169 18 18 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HNRNPM-201 HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie, biogrid 77 463 50 50 0
HTRA4-201 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 42 15 0 0 0
IFI16-201 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 102 422 61 61 0
INTS14-201 INTS14 Q96SY0 Integrator complex subunit 14 chr15 Not Cancer Driver No 1 hippie 36 118 8 8 0
IQGAP1-201 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie 137 351 25 25 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KCMF1-201 KCMF1 Q9P0J7 E3 ubiquitin-protein ligase KCMF1 chr2 Not Cancer Driver No 1 hippie 43 270 30 30 0
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 46 65 13 13 0
LIN28A-202 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 Not Cancer Driver No 1 intact 30 86 11 11 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 402 91 13 13 20
MAP1LC3A-201 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 19 24 1 1 0
MAP4K2-201 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 Not Cancer Driver No 1 hippie 59 243 16 16 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MINK1-202 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie 86 742 42 42 0
MYLK4-201 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 49 78 9 9 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NCF1-201 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 intact, hippie 31 181 11 11 1
NCSTN-201 NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 69 72 10 10 1
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NF2-202 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 49 252 18 18 16
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
OTUB2-201 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie 22 0 0 0 0
PAGE4-201 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 13 102 13 13 0
PAK1IP1-201 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 Not Cancer Driver No 1 hippie 26 83 2 2 0
PAK4-203 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 46 344 27 27 0
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PHF8-204 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 intact, hippie 104 603 58 58 1
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PRKAB1-201 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 21 125 11 11 0
PRPF40A-213 PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 39 695 29 29 0
PRPF8-201 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 202 226 24 24 6
PSMC6-201 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 Not Cancer Driver No 1 hippie, biogrid 39 69 6 6 0
PSME3-210 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 16 25 5 5 0
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 425 76 5 5 37
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RACGAP1-201 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie 54 255 20 20 2
RAD18-201 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 42 330 31 31 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RCC1-214 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie, biogrid 44 146 16 16 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 64 420 31 31 0
RIOK1-202 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 52 303 30 30 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 99 232 31 31 3
RRP1B-201 RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 61 517 40 40 0
SERBP1-204 SERBP1 Q8NC51 SERPINE1 mRNA-binding protein 1 chr1 Not Cancer Driver No 1 hippie 40 408 40 40 0
SH2D3C-201 SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 81 443 52 52 0
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SNRNP70-206 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 28 417 27 27 0
SNRPD1-201 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 hippie, biogrid 4 80 0 0 0
SNRPD3-201 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 1 hippie, biogrid 14 43 11 11 0
SRSF5-217 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 23 189 15 15 0
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
TIFAB-201 TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 Not Cancer Driver No 1 intact, hippie 27 26 4 4 0
TNF-208 TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 22 45 2 2 0
TNFAIP3-206 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 Census, Compendium Yes 1 hippie 69 231 21 21 1
TNIK-204 TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 126 782 86 86 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TRADD-201 TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 intact, hippie 18 74 4 4 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 51 62 5 5 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
U2AF2-201 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie, biogrid 61 191 24 24 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 85 117 15 15 84
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 67 316 45 45 1
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WDR76-201 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 40 289 22 22 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
YBX1-201 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 intact 31 312 31 31 0
ZBTB38-201 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 95 649 49 49 0
ZC3H18-201 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 36 929 33 33 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0